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Metabolic Engineering For Bioactive Compounds


Metabolic Engineering For Bioactive Compounds
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Metabolic Engineering For Bioactive Compounds


Metabolic Engineering For Bioactive Compounds
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Author : Vipin Chandra Kalia
language : en
Publisher: Springer
Release Date : 2017-10-07

Metabolic Engineering For Bioactive Compounds written by Vipin Chandra Kalia and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-07 with Medical categories.


This book comprehensively discusses the latest research in the area of metabolic engineering. Metabolic engineering solutions for bioactive compounds are now being derived by means of heterologous gene expression, in a wide range of organisms. The book provides an overview of the model systems being employed for metabolic manipulation to yield bioactive molecules, such as single-cell proteins, antibody generation, metabolites, proteases, chaperones, therapeutic proteins, nanomaterials, polymeric conjugates, dendrimers and nanoassemblies, Escherichia coli, Agrobacterium, Saccharomyces cerevisiae and cell lines, etc. In addition, it shares insights into the scope of these methods in the areas of prevention, diagnosis and treatment of diseases, e.g. immunotherapy for curing various diseases like cancer, allergies, autoimmune diseases, etc.



Biotechnology Of Bioactive Compounds


Biotechnology Of Bioactive Compounds
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Author : Vijai Kumar Gupta
language : en
Publisher: John Wiley & Sons
Release Date : 2015-04-20

Biotechnology Of Bioactive Compounds written by Vijai Kumar Gupta and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-20 with Technology & Engineering categories.


Bioactive compounds play a central role in high-value product development in the chemical industry. Bioactive compounds have been identified from diverse sources and their therapeutic benefits, nutritional value and protective effects in human and animal healthcare have underpinned their application as pharmaceuticals and functional food ingredients. The orderly study of biologically active products and the exploration of potential biological activities of these secondary metabolites, including their clinical applications, standardization, quality control, mode of action and potential biomolecular interactions, has emerged as one of the most exciting developments in modern natural medicine. Biotechnology of Bioactive Compounds describes the current stage of knowledge on the production of bioactive compounds from microbial, algal and vegetable sources. In addition, the molecular approach for screening bioactive compounds is also discussed, as well as examples of applications of these compounds on human health. The first half of the book comprises information on diverse sources of bioactive compounds, ranging from microorganisms and algae to plants and dietary foods. The second half of the book reviews synthetic approaches, as well as selected bioactivities and biotechnological and biomedical potential. The bioactive compounds profiled include compounds such as C-phycocyanins, glycosides, phytosterols and natural steroids. An overview of the usage of bioactive compounds as antioxidants and anti-inflammatory agents, anti-allergic compounds and in stem cell research is also presented, along with an overview of the medicinal applications of plant-derived compounds. Biotechnology of Bioactive Compounds will be an informative text for undergraduate and graduate students of bio-medicinal chemistry who are keen to explore the potential of bioactive natural products. It also provides useful information for scientists working in various research fields where natural products have a primary role.



Biotechnological Production Of Bioactive Compounds


Biotechnological Production Of Bioactive Compounds
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Author : Madan L. Verma
language : en
Publisher: Elsevier
Release Date : 2019-07-20

Biotechnological Production Of Bioactive Compounds written by Madan L. Verma and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-20 with Technology & Engineering categories.


Biotechnological Production of Bioactive Compounds provides insights on the most recent innovations, trends, concerns, solutions and practical challenges encountered in the fields of enzyme technology and nanobiotechnology for the production of bioactive materials with extra health benefits. As nanobiotechnology has improved the bioactive extraction process significantly, many bioactives, including bioflavonoids, omega-3 fatty acids, biopigments and low calorie sugar substitutes are a pivotal part of the food industry. The book highlights the production of extra health benefits "bioactives'' from plants and microbes and explains how the extraction efficiency of bioactives molecules improves significantly with the recent advances in nanobiotechnology. Researchers in the fields of biochemical engineering, biotechnology, bioremediation, environmental sustainability and those in pharma industries will find the information in this book very helpful and illuminating. - Outlines technological advances in bioactives extraction - Covers bioflavonoids, biopigments, omega-3-fatty acids and low sugar substitutes - Explains the mechanisms of Green cargo (biogenic nanoparticles) for the delivery of bioactive molecules



An Introduction To Metabolic And Cellular Engineering


An Introduction To Metabolic And Cellular Engineering
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Author : Sonia Cortassa
language : en
Publisher: World Scientific
Release Date : 2002

An Introduction To Metabolic And Cellular Engineering written by Sonia Cortassa and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Science categories.


Metabolic and cellular engineering is a powerful alliance of two technologies: genetics-molecular biology and fermentation technology.



Metabolic Engineering Of Plant Secondary Metabolism


Metabolic Engineering Of Plant Secondary Metabolism
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Author : R. Verpoorte
language : en
Publisher: Springer Science & Business Media
Release Date : 2000-11-30

Metabolic Engineering Of Plant Secondary Metabolism written by R. Verpoorte and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-11-30 with Medical categories.


Plant secondary metabolism is an economically important source of fine chemicals, such as drugs, insecticides, dyes, flavours, and fragrances. Moreover, important traits of plants such as taste, flavour, smell, colour, or resistance against pests and diseases are also related to secondary metabolites. The genetic modification of plants is feasible nowadays. What does the possibility of engineering plant secondary metabolite pathways mean? In this book, firstly a general introduction is given on plant secondary metabolism, followed by an overview of the possible approaches that could be used to alter secondary metabolite pathways. In a series of chapters from various authorities in the field, an overview is given of the state of the art for important groups of secondary metabolites. No books have been published on this topic so far. This book will thus be a unique source of information for all those involved with plants as chemical factories of fine chemicals and those involved with the quality of food and ornamental plants. It will be useful in teaching graduate courses in the field of metabolic engineering in plants.



Bioactive Compounds From Natural Sources


Bioactive Compounds From Natural Sources
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Author : Corrado Tringali
language : en
Publisher: CRC Press
Release Date : 2011-09-27

Bioactive Compounds From Natural Sources written by Corrado Tringali and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-27 with Health & Fitness categories.


The first edition of Bioactive Compounds from Natural Sources was published in a period of renewed attention to biologically active compounds of natural origin. This trend has continued and intensified-natural products are again under the spotlight, in particular for their possible pharmacological applications. Largely focusing on natural products



Plant Bioactive Molecules


Plant Bioactive Molecules
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Author : Massimo Maffei
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2019-01-18

Plant Bioactive Molecules written by Massimo Maffei and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-18 with Medical categories.


Plants have always been a source of nourishment and healing for living things. Their dual task of producing nutrients and medicines has played a key role in the evolution of herbivore and omnivore organisms. The so-called secondary metabolites are molecules with well-defined functional roles. These compounds are produced to defend plants from abiotic and biotic stresses. The complexity of the molecular structures produced by plants is only equal to their versatility and chemical diversity, while the harmonic intertwining of biosynthetic and metabolic pathways offers a perfect picture of the adaptive plasticity of plants to changing environmental conditions. This book is divided into three parts designed to provide the reader with a general overview, a biochemical and a biotechnological approach to plant bioactive molecules. The first part analyses the concepts of chemical diversity, sustainability and functional role of bioactive molecules, by exploring the sites of synthesis and accumulation, the plant defence strategies and the use of bioactive molecules as food supplements and as a source for natural products to fight diseases. The first part ends with the study of chemotaxonomy. The second part is dedicated to plant biochemistry, with the detailed description of the main biosynthetic pathways leading to the synthesis of phenols and flavonoids, terpenes, oxylipins and nitrogen-containing substances. The third and final part describes plant biotechnology and production of bioactive molecules with industrial processes, both in vivo and in vitro. Special attention is paid to cell and tissue cultures, roots and shoots cultures, technological aspects describing bioreactors, biofermenters and photobioreactors. The book concludes with a chapter describing the genetic engineering strategies for the production of plant bioactive molecules, facing with ethical problems, risks and benefits of using recombinant DNA in genetically modified organisms (GMOs) and the use of molecular pharming, with a general discussion on food safety.



Metabolic Engineering


Metabolic Engineering
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Author : Sang Yup Lee
language : en
Publisher: John Wiley & Sons
Release Date : 2021-06-02

Metabolic Engineering written by Sang Yup Lee and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-02 with Science categories.


Learn more about foundational and advanced topics in metabolic engineering in this comprehensive resource edited by leaders in the field Metabolic Engineering: Concepts and Applications delivers a one-stop resource for readers seeking a complete description of the concepts, models, and applications of metabolic engineering. This guide offers practical insights into the metabolic engineering of major cell lines, including E. Coli, Bacillus and Yarrowia Lipolytica, and organisms, including human, animal, and plant). The distinguished editors also offer readers resources on microbiome engineering and the use of metabolic engineering in bioremediation. Written in two parts, Metabolic Engineering begins with the essential models and strategies of the field, like Flux Balance Analysis, Quantitative Flux Analysis, and Proteome Constrained Models. It also provides an overview of topics like Pathway Design, Metabolomics, and Genome Editing of Bacteria and Eukarya. The second part contains insightful descriptions of the practical applications of metabolic engineering, including specific examples that shed light on the topics within. In addition to subjects like the metabolic engineering of animals, humans, and plants, you’ll learn more about: Metabolic engineering concepts and a historical perspective on their development The different modes of analysis, including flux balance analysis and quantitative flux analysis An illuminating and complete discussion of the thermodynamics of metabolic pathways The Genome architecture of E. coli, as well as genome editing of both bacteria and eukarya An in-depth treatment of the application of metabolic engineering techniques to organisms including corynebacterial, bacillus, and pseudomonas, and more Perfect for students of biotechnology, bioengineers, and biotechnologists, Metabolic Engineering: Concepts and Applications also has a place on the bookshelves of research institutes, biotechnological institutes and industry labs, and university libraries. It's comprehensive treatment of all relevant metabolic engineering concepts, models, and applications will be of use to practicing biotechnologists and bioengineers who wish to solidify their understanding of the field.



Metabolic Engineering In Plants


Metabolic Engineering In Plants
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Author : Tariq Aftab
language : en
Publisher: Springer Nature
Release Date : 2022-06-01

Metabolic Engineering In Plants written by Tariq Aftab and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-01 with Science categories.


This edited book highlights the plant and cell/organ culture systems, and environmental and genetic transformation-based modulation of biochemical pathways. Special focus is given to microRNA-based technology, heterologous systems expression of enzymes and pathways leading to products of interest, as well as applications using both model and non-model plant species. Metabolic engineering is usually defined as the re-routing of one or more enzymatic reactions to generate new compounds, increase the production of existing compounds, or facilitate the degradation of compounds. Plants are the foundation of numerous compounds which are synthesized via assimilated complex biosynthetic routes. Plants have evolved an incredible arrangement of metabolic pathways leading to molecules/compounds capable of responding promptly and effectively to stress situations imposed by biotic and abiotic factors, some of which supply the ever-growing needs of humankind for natural chemicals, such as pharmaceuticals, nutraceuticals, agrochemicals, food and chemical additives, biofuels, and biomass. However, in foreseeable future we will be forced to think about the accessibility of resources for the generations to come. For these reasons, the book proposes alternative options of food/food supplement, medicines and other essential items, by using plant metabolic engineering approach. This book is of interest to teachers, researchers and academic experts. Also, the book serves as additional reading material for undergraduate and graduate students of biotechnology and molecular biology of plants.



Plant Secondary Metabolic Regulation And Engineering


Plant Secondary Metabolic Regulation And Engineering
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Author : Fangyuan Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-17

Plant Secondary Metabolic Regulation And Engineering written by Fangyuan Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-17 with Science categories.