Metabolic Engineering Principles And Methodologies
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Metabolic Engineering
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Author : George Stephanopoulos
language : en
Publisher: Elsevier
Release Date : 1998-10-17
Metabolic Engineering written by George Stephanopoulos and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-10-17 with Science categories.
Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The objective is to identify specific genetics or environmental manipulations that result in improvements in yield and productivities of biotechnological processes. Key features of the book are pathway integration and the focus on metabolic flux as a fundamental determinant of cell physiology. The book keeps mathematical complexity to a minimum, and provides a glossary of biological terms to facilitate use of the book by a broader spectrum of readers. A web page exists to communicate updates of the codes and homework problems. - Demonstrates metabolic engineering in action with numerous examples of pathway modification - Includes methods for identifying key enzymes in metabolic networks - Contains a comprehensive review of metabolic biochemistry - Discusses metabolic regulation at the gene, enzyme, operon, and cell levels - Explains concepts of stoichiometry, kinetics, and thermodynamics of metabolic pathways - Minimizes mathematical complexity - Links to a Web page to communicate updates of the software code and homework problems
Metabolic Engineering Principles And Methodologies
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Author : Mr. Rohit Manglik
language : en
Publisher: EduGorilla Publication
Release Date : 2024-07-02
Metabolic Engineering Principles And Methodologies written by Mr. Rohit Manglik and has been published by EduGorilla Publication this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-02 with Science categories.
EduGorilla Publication is a trusted name in the education sector, committed to empowering learners with high-quality study materials and resources. Specializing in competitive exams and academic support, EduGorilla provides comprehensive and well-structured content tailored to meet the needs of students across various streams and levels.
Metabolic Engineering
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Author : Sang Yup Lee
language : en
Publisher: CRC Press
Release Date : 1999-09-29
Metabolic Engineering written by Sang Yup Lee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-09-29 with Science categories.
This unique reference/text presents the basic theory and practical applications of metabolic engineering (ME). It offers systematic analysis of complex metabolic pathways and ways of employing recombinant DNA techniques to alter cell behavior, metabolic patterns, and product formation. Treating ME as a distinct subfield of genetic engineering, the book demonstrates new means of enabling cells to produce valuable proteins, polypeptides, and primary and secondary metabolites. Written by more than 35 leading international experts in the field, this book discusses metabolic engineering in plant and mammalian cells, bacteria, and yeasts and assesses metabolic engineering applications in agriculture, pharmaceuticals, and environmental systems. It illuminates the potential of the "cell factory" model for production of chemicals and therapeutics and examines methods for developing new antiviral and antibacterial molecules and effective gene and somatic-cell therapies. Metabolic Engineering also addresses the use of metabolic flux analysis, metabolic control analysis, and online metabolic flux analysis.
Metabolic Engineering Principles And Methodologies
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Author : G. Stephanopoulos
language : en
Publisher:
Release Date : 1998
Metabolic Engineering Principles And Methodologies written by G. Stephanopoulos and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.
Bioseparations Science And Engineering
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Author : Roger G. Harrison
language : en
Publisher: Oxford University Press, USA
Release Date : 2015
Bioseparations Science And Engineering written by Roger G. Harrison and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Science categories.
An updated edition of a comprehensive and authoritative chemical engineering textbook on bioseparations science, updated to include new information on topics like moment analysis, chromatography, and evaporation.
Systems Metabolic Engineering
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Author : Christoph Wittmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-06-15
Systems Metabolic Engineering written by Christoph Wittmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-15 with Science categories.
Systems Metabolic Engineering is changing the way microbial cell factories are designed and optimized for industrial production. Integrating systems biology and biotechnology with new concepts from synthetic biology enables the global analysis and engineering of microorganisms and bioprocesses at super efficiency and versatility otherwise not accessible. Without doubt, systems metabolic engineering is a major driver towards bio-based production of chemicals, materials and fuels from renewables and thus one of the core technologies of global green growth. In this book, Christoph Wittmann and Sang-Yup Lee have assembled the world leaders on systems metabolic engineering and cover the full story – from genomes and networks via discovery and design to industrial implementation practises. This book is a comprehensive resource for students and researchers from academia and industry interested in systems metabolic engineering. It provides us with the fundaments to targeted engineering of microbial cells for sustainable bio-production and stimulates those who are interested to enter this exiting research field.
Metabolic Engineering
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Author : G. Stephanopoulos
language : en
Publisher:
Release Date : 1998
Metabolic Engineering written by G. Stephanopoulos and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Medical categories.
Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The objective is to identify specific genetics or environmental manipulations that result in improvements in yield and productivities of biotechnological processes. Key features of the book are pathway integration and the focus on metabolic flux as a fundamental determinant of cell physiology. The book keeps mathematical complexity to a minimum, and provides a glossary of biological terms to facilitate use of the book by a broader spectrum of readers. A web page exists to communicate updates of the codes and homework problems. Key Features * Demonstrates metabolic engineering in action with numerous examples of pathway modification * Includes methods for identifying key enzymes in metabolic networks * Contains a comprehensive review of metabolic biochemistry * Discusses metabolic regulation at the gene, enzyme, operon, and cell levels * Explains concepts of stoichiometry, kinetics, and thermodynamics of metabolic pathways * Minimizes mathematical complexity * Links to a Web page to communicate updates of the software code and homework problems
Bioreaction Engineering Principles
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Author : Jens Nielsen
language : en
Publisher: Springer
Release Date : 2012-12-06
Bioreaction Engineering Principles written by Jens Nielsen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Technology & Engineering categories.
This is the second edition of the text "Bioreaction Engineering Principles" by Jens Nielsen and John Villadsen, originally published in 1994 by Plenum Press (now part of Kluwer). Time runs fast in Biotechnology, and when Kluwer Plenum stopped reprinting the first edition and asked us to make a second, revised edition we happily accepted. A text on bioreactions written in the early 1990's will not reflect the enormous development of experimental as well as theoretical aspects of cellular reactions during the past decade. In the preface to the first edition we admitted to be newcomers in the field. One of us (JV) has had 10 more years of job training in biotechnology, and the younger author (IN) has now received international recognition for his work with the hottest topics of "modem" biotechnology. Furthermore we are happy to have induced Gunnar Liden, professor of chemical reaction engineering at our sister university in Lund, Sweden to join us as co-author of the second edition. His contribution, especially on the chemical engineering aspects of "real" bioreactors has been of the greatest value. Chapter 8 of the present edition is largely unchanged from the first edition. We wish to thank professor Martin Hjortso from LSU for his substantial help with this chapter.
Bioprocess Engineering Principles
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Author : Pauline M. Doran
language : en
Publisher: Elsevier
Release Date : 1995-04-03
Bioprocess Engineering Principles written by Pauline M. Doran and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-04-03 with Science categories.
The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in co-operation with chemical engineers to achieve pragmatic commercial goals. For many years aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists.This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant cells, plant and animal cell cultures, immobilised catalysts as well as traditional fermentation systems.* * First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists* Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems* Comprehensive, single-authored* 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems* 13 chapters, organized according to engineering sub-disciplines, are groupled in four sections - Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors* Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading* Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used* Suitable for course adoption - follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels.
Basic Biotechnology
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Author : Colin Ratledge
language : en
Publisher: Cambridge University Press
Release Date : 2006-05-25
Basic Biotechnology written by Colin Ratledge and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-05-25 with Medical categories.
Biotechnology is one of the major technologies of the twenty-first century. Its wide-ranging, multi-disciplinary activities include recombinant DNA techniques, cloning and the application of microbiology to the production of goods from bread to antibiotics. In this new edition of the textbook Basic Biotechnology, biology and bioprocessing topics are uniquely combined to provide a complete overview of biotechnology. The fundamental principles that underpin all biotechnology are explained and a full range of examples are discussed to show how these principles are applied; from starting substrate to final product. A distinctive feature of this text are the discussions of the public perception of biotechnology and the business of biotechnology, which set the science in a broader context. This comprehensive textbook is essential reading for all students of biotechnology and applied microbiology, and for researchers in biotechnology industries.