Metabolism Of Human Diseases


Metabolism Of Human Diseases
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Metabolism Of Human Diseases


Metabolism Of Human Diseases
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Author : Eckhard Lammert
language : en
Publisher: Springer
Release Date : 2014-06-11

Metabolism Of Human Diseases written by Eckhard Lammert and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-11 with Medical categories.


“Metabolism of Human Diseases” examines the physiology of key organs (e.g. brain, eye, lung, heart, blood vessels, blood, immune system, gastrointestinal tract, pancreas, liver, fat tissue, kidney, reproductive system, teeth, bone and joints) and how defective metabolism and signaling pathways within these organs contribute to common human diseases. The latter include depression, schizophrenia, epilepsy, Parkinson's disease, Alzheimer's disease, migraine, multiple sclerosis, Down syndrome, macular degeneration, glaucoma, asthma, COPD, pneumonia, atherosclerotic heart disease, heart failure, stroke, varicose veins, Sickle cell disease, hyperlipidemia, fever, sepsis, allergies, peptic ulcer, gastroenteritis, lactose intolerance, colon cancer, diabetes, cirrhosis, metabolic syndrome, hypertension, chronic kidney disease, gout, urinary tract infections, kidney stones, dental caries, osteoporosis, osteoarthritis, rheumatoid arthritis, breast cancer and prostate cancer. The book also describes commonly used drugs and explains their molecular targets. It provides the first comprehensive and detailed summary of the metabolism of individual organs and their physiological and pathological functioning. Thus it serves as a useful supplement to previous textbooks of human physiology. “Metabolism of Human Diseases” is a must-have, state-of-the-art textbook written by International experts for graduate students, postdocs and scientists in metabolic research, biochemistry, physiology and pharmacy as well as for physicians interested in molecular mechanisms underlying common human diseases.



Metabolism Of Human Diseases


Metabolism Of Human Diseases
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Author : Eckhard Lammert
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-06-02

Metabolism Of Human Diseases written by Eckhard Lammert and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-02 with Medical categories.


“Metabolism of Human Diseases” examines the physiology of key organs (e.g. brain, eye, lung, heart, blood vessels, blood, immune system, gastrointestinal tract, pancreas, liver, fat tissue, kidney, reproductive system, teeth, bone and joints) and how defective metabolism and signaling pathways within these organs contribute to common human diseases. The latter include depression, schizophrenia, epilepsy, Parkinson's disease, Alzheimer's disease, migraine, multiple sclerosis, Down syndrome, macular degeneration, glaucoma, asthma, COPD, pneumonia, atherosclerotic heart disease, heart failure, stroke, varicose veins, Sickle cell disease, hyperlipidemia, fever, sepsis, allergies, peptic ulcer, gastroenteritis, lactose intolerance, colon cancer, diabetes, cirrhosis, metabolic syndrome, hypertension, chronic kidney disease, gout, urinary tract infections, kidney stones, dental caries, osteoporosis, osteoarthritis, rheumatoid arthritis, breast cancer and prostate cancer. The book also describes commonly used drugs and explains their molecular targets. It provides the first comprehensive and detailed summary of the metabolism of individual organs and their physiological and pathological functioning. Thus it serves as a useful supplement to previous textbooks of human physiology. “Metabolism of Human Diseases” is a must-have, state-of-the-art textbook written by International experts for graduate students, postdocs and scientists in metabolic research, biochemistry, physiology and pharmacy as well as for physicians interested in molecular mechanisms underlying common human diseases.



Medical Biochemistry


Medical Biochemistry
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Author : Miriam D. Rosenthal
language : en
Publisher: Wiley
Release Date : 2009-03-30

Medical Biochemistry written by Miriam D. Rosenthal and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-30 with Science categories.


Metabolism includes various pathways of chemical reactions; understanding these pathways leads to an improved knowledge of the causes, preventions, and cures for human diseases. Medical Biochemistry: Human Metabolism in Health and Disease provides a concise yet thorough explanation of human metabolism and its role in health and diseases. Focusing on the physiological context of human metabolism without extensive consideration of the mechanistic principles of underlying enzymology, the books serves as both a primary text and resource for students and professional in medical, dental, and allied health programs.



Lipid Metabolism And Human Diseases


Lipid Metabolism And Human Diseases
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Author : Da-wei Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-28

Lipid Metabolism And Human Diseases written by Da-wei Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-28 with Science categories.


Lipids such as cholesterol, phospholipids, triglycerides, and free fatty acids, play various essential physiological roles. Dysregulation of lipid metabolism causes dyslipidemia, which is a critical factor in the development of various human diseases, such as cardiovascular disease, diabetes, non-alcoholic fatty liver disease, Alzheimer's disease, and Niemann-Pick disease. Therefore, lipid homeostasis in humans is strictly regulated by a well-balanced mechanism of intestinal uptake, endogenous synthesis and metabolism, and transport in lipoprotein particles and excretion. The human body evolves multiple mechanisms to maintain lipid homeostasis, such as low-density lipoprotein receptor mediates clearance of circulating low-density lipoprotein cholesterol; phospholipid transfer protein mediates the transfer of phospholipids from apoB-containing triglyceride-rich lipoprotein to high-density lipoprotein, etc.



Inborn Errors Of Metabolism In Humans


Inborn Errors Of Metabolism In Humans
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Author : Forrester Cockburn
language : en
Publisher:
Release Date : 1982

Inborn Errors Of Metabolism In Humans written by Forrester Cockburn and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medical categories.




Metabolism Of Minerals And Trace Elements In Human Disease


Metabolism Of Minerals And Trace Elements In Human Disease
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Author : Mohamed Abdulla
language : en
Publisher:
Release Date : 1989

Metabolism Of Minerals And Trace Elements In Human Disease written by Mohamed Abdulla and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Deficiency diseases categories.




Medical Biochemistry


Medical Biochemistry
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Author : Miriam D. Rosenthal
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-20

Medical Biochemistry written by Miriam D. Rosenthal and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-20 with Science categories.


Metabolism includes various pathways of chemical reactions; understanding these pathways leads to an improved knowledge of the causes, preventions, and cures for human diseases. Medical Biochemistry: Human Metabolism in Health and Disease provides a concise yet thorough explanation of human metabolism and its role in health and diseases. Focusing on the physiological context of human metabolism without extensive consideration of the mechanistic principles of underlying enzymology, the books serves as both a primary text and resource for students and professional in medical, dental, and allied health programs.



Inherited Metabolic Diseases


Inherited Metabolic Diseases
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Author : Georg F. Hoffmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-11-21

Inherited Metabolic Diseases written by Georg F. Hoffmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-21 with Medical categories.


The explosion of insights in the field of metabolic disease has shed new light on diagnostic as well as treatment options. ‘Inherited Metabolic Disease – A Clinical Approach’ is written with a reader-friendly consistent structure. It helps the reader to find the information in an easily accessible and rapid way when needed. Starting with an overview of the major groups of metabolic disorders it includes algorithms with questions and answers as well as numerous graphs, metabolic pathways, and an expanded index. Clinical and diagnostic details with a system and symptom based are given to facilitate an efficient and yet complete diagnostic work-up of individual patients. Further, it offers helpful advice for emergency situations, such as hypoglycemia, hyperammonemia, lactic acidosis or acute encephalopathy. Five different indices allow a quick but complete orientation for common important constellations. Last but not least, it has an appendix with a guide to rapid differential diagnosis of signs and symptoms and when not to suspect metabolic disease. It will help physicians to diagnose patients they may otherwise fail to diagnose and to reduce unnecessary referrals. For metabolic and genetic specialists especially the indices will be helpful as a quick look when being called for advice. It has all it needs to become a gold standard defining the clinical practice in this field.



Human Metabolism


Human Metabolism
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Author : Keith N. Frayn
language : en
Publisher: John Wiley & Sons
Release Date : 2019-03-13

Human Metabolism written by Keith N. Frayn and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-13 with Medical categories.


The updated bestselling guide to human metabolism and metabolic regulation The revised and comprehensively updated new edition of Human Metabolism (formerly Metabolic Regulation – A Human Perspective) offers a current and integrated review of metabolism and metabolic regulation. The authors explain difficult concepts in clear and concise terms in order to provide an accessible and essential guide to the topic. This comprehensive text covers a wide range of topics such as energy balance, body weight regulation, exercise, and how the body copes with extreme situations, and illustrates how metabolic regulation allows the human body to adapt to many different conditions. This fourth edition has been revised with a new full colour text design and helpful illustrations that illuminate the regulatory mechanisms by which all cells control the metabolic processes necessary for life. The text includes chapter summaries and additional explanatory text that help to clarify the information presented. In addition, the newly revised edition includes more content on metabolic pathways and metabolic diseases. This important resource: Is a valuable tool for scientists, practitioners and students across a broad range of health sciences including medicine, biochemistry, nutrition, dietetics, sports science and nursing Includes a full colour text filled with illustrations and additional diagrams to aid understanding Offers a companion website with additional learning and teaching resources. Written for students of medicine, biochemistry, nutrition, dietetics, sports science and nursing, Human Metabolism has been revised and updated to provide a comprehensive review of metabolism and metabolic regulation.



The Mrna Metabolism In Human Disease


The Mrna Metabolism In Human Disease
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Author : Luísa Romão
language : en
Publisher: Springer
Release Date : 2019-07-24

The Mrna Metabolism In Human Disease written by Luísa Romão and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-24 with Medical categories.


The eukaryotic gene expression pathway involves a number of interlinked steps, with messenger RNA (mRNA) being the key intermediate. The precursor mRNA is transcribed from DNA, processed by removal of introns and addition of the cap structure and the poly(A) tail. The mature mRNA is then exported to the cytoplasm where it is translated into protein and finally degraded. In this process, mRNA is associated with RNA-binding proteins forming ribonucleoprotein complexes, whose protein content evolves throughout the lifetime of the mRNA. While the complexity of eukaryotic gene expression allows the production of proteins to be controlled at many levels, it also makes the process vulnerable to errors. Although eukaryotic cells have evolved elaborate mRNA quality control mechanisms that ensure the fidelity of gene expression, some defects are not detected, thus affecting mRNA metabolism. This condition plays a fundamental role in the pathogenesis of several disease processes, such as neurodegeneration and oncogenesis. Besides, exciting recent data have shown that cellular RNAs can be modified post-transcriptionally via dynamic and reversible chemical modifications, the so-called epitranscriptome. These modifications can alter mRNA structure, being able to modulate different steps of the mRNA metabolism that can be associated with various human diseases, such as systemic lupus erythematosus and cancer. This book provides a collection of novel studies and hypotheses aimed to define the pathophysiological consequences of altered mRNA metabolism events in human cells, and is written for a wide spectrum of readers in the field of gene expression regulation. The last chapter highlights how the discovery of disease-causing defects (or modifications) in mRNA can provide a variety of therapeutic targets that can be used for the development of new RNA-based therapeutics. Hopefully, it may also contribute to inspire the drug-developing scientific community.