Metabolomics And Ethnopharmacology In The Development Of Herbal And Traditional Medicine
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Metabolomics And Ethnopharmacology In The Development Of Herbal And Traditional Medicine
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Author : Sayeed Ahmad
language : en
Publisher: Frontiers Media SA
Release Date : 2022-04-25
Metabolomics And Ethnopharmacology In The Development Of Herbal And Traditional Medicine written by Sayeed Ahmad and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-25 with Science categories.
Quality Control And Evaluation Of Herbal Drugs
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Author : Pulok K. Mukherjee
language : en
Publisher: Elsevier
Release Date : 2019-05-30
Quality Control And Evaluation Of Herbal Drugs written by Pulok K. Mukherjee and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-30 with Science categories.
Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs’ activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities
Mass Spectrometry Based Metabolomics In Clinical And Herbal Medicines
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Author : Aihua Zhang
language : en
Publisher: John Wiley & Sons
Release Date : 2021-08-20
Mass Spectrometry Based Metabolomics In Clinical And Herbal Medicines written by Aihua Zhang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-20 with Science categories.
Highlights the importance and benefit of mass spectrometry-based metabolomics for identifying biomarkers that accurately screen for potential biomarkers of diseases Mass spectrometry-based metabolomics offer new opportunities for biomarker discovery in complex diseases and may provide pathological understanding of diseases beyond traditional technologies. It is the systematic analysis of low-molecular-weight metabolites in biological samples and has been applied to discovering and identifying the perturbed pathways. Currently, mass spectrometry-based metabolomics has become an important tool in clinical research and the diagnosis of human disease. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines comprehensively presents the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics such as metabolites analysis, biomarker discovery, technical challenges, discovery of natural product, mechanism interpretation of action, discovery of active ingredients, clinical application and precision medicine, and enhancing their biomedical value in a real world of biomedicine, shedding light on the potential for spectrometry-based metabolomics. It highlights the value of mass spectrometry-based metabolomics and metabolism to address the complexity of herbal medicines in systems pharmacology, especially, to link phytochemical analysis with the assessment of pharmacological effect and therapeutic potential. Each chapter has been laid out with introduction, method, up-to-date literature, identification of biomarker, and applications Covers the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics in the discovery of biomarker, active ingredients, natural product, etc. Constitutes a unique and indispensable practical guide for any phytochemistry or related laboratory, and provides hands-on description of new techniques Provides a guide for new practitioners of pharmacologists, pharmacological scholars, drug developers, botanist, researchers of traditional medicines. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines provides a landmark of mass spectrometry-based metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all biomedical science fields.
Ethnopharmacology
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Author : Michael Heinrich
language : en
Publisher: John Wiley & Sons
Release Date : 2015-10-12
Ethnopharmacology written by Michael Heinrich and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-12 with Medical categories.
Ethnopharmacology is one of the world’s fastest-growing scientific disciplines encompassing a diverse range of subjects. It links natural sciences research on medicinal, aromatic and toxic plants with socio-cultural studies and has often been associated with the development of new drugs. The Editors of Ethnopharmacology have assembled an international team of renowned contributors to provide a critical synthesis of the substantial body of new knowledge and evidence on the subject that has emerged over the past decade. Divided into three parts, the book begins with an overview of the subject including a brief history, ethnopharmacological methods, the role of intellectual property protection, key analytical approaches, the role of ethnopharmacology in primary/secondary education and links to biodiversity and ecological research. Part two looks at ethnopharmacological contributions to modern therapeutics across a range of conditions including CNS disorders, cancer, bone and joint health and parasitic diseases. The final part is devoted to regional perspectives covering all continents, providing a state-of-the –art assessment of the status of ethnopharmacological research globally. A comprehensive, critical synthesis of the latest developments in ethnopharmacology. Includes a section devoted to ethnopharmacological contributions to modern therapeutics across a range of conditions. Contributions are from leading international experts in the field. This timely book will prove invaluable for researchers and students across a range of subjects including ethnopharmacology, ethnobotany, medicinal plant research and natural products research. Ethnopharmacology- A Reader is part of the ULLA Series in Pharmaceutical Sciences www.ullapharmsci.org
Chinmedomics
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Author : Xijun Wang
language : en
Publisher: Academic Press
Release Date : 2015-07-15
Chinmedomics written by Xijun Wang and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-15 with Science categories.
Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine uses new experimental techniques and research to open doors in drug discovery and development related to traditional Chinese medicine (TCM). This book features a unique approach that combines chemometric analysis with metabolomics studies to illuminate significant changes that have occurred in syndrome states while simultaneously analyzing the efficacy of chemical ingredients in herbal medicines. Chapters provide cutting-edge information on traditional medicine, analytical technology, natural products, metabolomics, bioinformatics and their applications. This book provides a valuable resource for pharmacologists, pharmaceutical scientists, medicinal plant researchers, pharmacognosists and chemists working with TCM and highlights ways to further research and advances in this area in the future. Presents a practical guide for new practitioners of Chinmedomics with insights on the current use and future development of this method Each chapter includes an introduction, method, references to the latest literature, possible mechanisms of action and applications Edited by the leading experts of research related to Chinmedomics
Evidence Based Validation Of Herbal Medicine
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Author : Pulok K. Mukherjee
language : en
Publisher: Elsevier
Release Date : 2022-07-12
Evidence Based Validation Of Herbal Medicine written by Pulok K. Mukherjee and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-12 with Business & Economics categories.
Evidence-Based Validation of Herbal Medicines: Translational Research on Botanicals brings together current thinking and practice in the characterization and validation of natural products. The book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand compounds responsible and their probable underlying mechanisms of action. This book brings together the views, expertise and experiences of scientific experts in the field of medicinal plant research, hence it will be useful for researcher who want to know more about the natural lead with their validation and also useful to exploit traditional medicines. Includes state-of-the-art methods for detecting, isolating and performing structure elucidation by degradation and spectroscopic techniques Highlights the trends in validation and value addition of herbal medicine with different scientific approaches used in therapeutics Contains several all-new chapters on topics such as traditional-medicine-inspired drug development to treat emerging viral diseases, medicinal plants in antimicrobial resistance, TLC bio profiling, botanicals as medicinal foods, bioprospecting and bioassay-guided isolation of medicinal plants, immunomodulators from medicinal plants, and more
Drug Discovery And Development
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Author : Bhushan Patwardhan
language : en
Publisher: Nipa
Release Date : 2023-06-14
Drug Discovery And Development written by Bhushan Patwardhan and has been published by Nipa this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-14 with Medical categories.
While biotechnological advances, genomics and high throughput screenings or combinatorial and asymmetric syntheses are opening new opportunities in drug discovery, the industry is facing serious innovation deficit. The total number of new molecules registered per year has dropped in contrast to expected increase. Post marketing failures of blockbuster drugs have become major concerns of industries. On the other side, globally there is a major shift to sue of traditional medicine involving complementary and alternative therapies. Ethnopharmacology and traditional medicines have contributed in past significantly in the process of natural product drug discovery. There are two clear tracks where ethnopharmacology has potential to contribute in future drug research. First, as a discovery engine to provide new targets, leads, and second, use of quality assured and standardized traditional medicines. In this scenario, it is important to understand the mechanisms of drug discovery and pharmaceutical development with a focus on herbal drugs and neutraceutical. This book provides historical perspective, future prospects and significance of ethnopharmacology in drug research. It also provides important steps in botanical drug discovery and development including bioprospecting, quality control, standardization, pharmaceutics, stability, pharmacokinetics, and bioavailability with examples from ethnopharmacology and herbal medicine. One of the important feature of this book is to give an excellent insight to Good Laboratory and Good Clinical Practices along with very useful summary steps involved in filing IND or NDA of botanical products. The book also gives Regulators' perspective of validating claims and how ethnopharmacological or traditional medicines need different approach.
Plants As Medicine And Aromatics
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Author : Mohd Kafeel Ahmad Ansari
language : en
Publisher: CRC Press
Release Date : 2023-02-27
Plants As Medicine And Aromatics written by Mohd Kafeel Ahmad Ansari and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-27 with Medical categories.
Since ancient times, plants serve as a valuable source of traditional herbal medicines. Unlike modern medicines, herbal medicines have consistently demonstrated health advantages, including a lack of serious adverse side effects, long-lasting curative impacts and overall cost-effectiveness. Even today, with various modern pharmaceutical medicines commonly available, plant-based medicines and aromatics are increasingly in demand throughout the health sector globally, where they are used not only for the treatment of disease, but also, preventatively for maintaining good health. People are seeking alternatives to modern medical treatments turning to phytomedicine for primary health care. However, an inadvertent consequence of this increased demand for herbal medicines has resulted in medicinal plants being threatened due to their initial small population sizes, narrow distribution areas, habitat specificity, and increasingly destructive non-sustainable harvesting. This book critically examines and reviews the status of medicinal plants and includes several important case studies of representative plant species. It contains information on aspects concerning phytochemistry, natural products, cultivation, conservation techniques, environmental interactions, and therapeutic features of medicinal aromatic plants. Features Evaluates plants as medicine and aromatics covering pharmacognosy and ecology of plants having therapeutic values. Discusses how plants can play a role in treatment of diseases and as potential therapeutics standards for maintaining good health. Presents conventional and contemporary approaches to conservation of such plants with commercial feasibility.
Metabolome Analysis
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Author : Silas G. Villas-Boas
language : en
Publisher: John Wiley & Sons
Release Date : 2007-02-16
Metabolome Analysis written by Silas G. Villas-Boas and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-16 with Science categories.
Providing information on the main approaches for the analysis of metabolites, this textbook: Covers basic methodologies in sample preparation and separation techniques, as well as the most recent techniques of mass spectrometry. Differentiates between primary and secondary metabolites. Includes four chapters discussing successful metabolome studies of different organisms. Highlights the analytical challenges of studying metabolites. Illustrates applications of metabolome analysis through the use of case studies.
Understanding Traditional Chinese Medicine
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Author : Friedrich G. Wallner
language : en
Publisher: Peter Lang Gmbh, Internationaler Verlag Der Wissenschaften
Release Date : 2009
Understanding Traditional Chinese Medicine written by Friedrich G. Wallner and has been published by Peter Lang Gmbh, Internationaler Verlag Der Wissenschaften this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Manners and customs categories.
This volume presents texts written by Austrian and Chinese experts in the field of Traditional Chinese Medicine. The issue the authors worked on is the basic problem how to make a different system of medical thinking plausible for the Western world, especially for Western medicine. This issue is considered from different viewpoints - from the viewpoint of Western medicine that is familiar with Chinese medicine and contrariwise from the viewpoint of Chinese Medicine that is familiar with its Western counterpart and from a philosophical viewpoint. In this way both differences in the theoretical systems of Western and Chinese medicine and problems of adequate translation are profundly discussed.