Metastasis Of Breast Cancer
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Metastasis Of Breast Cancer
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Author : R.E. Mansel
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-06-14
Metastasis Of Breast Cancer written by R.E. Mansel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-14 with Health & Fitness categories.
Written by experts in the subject area, the book covers a broad range of topics in the metastasis of breast cancer, from genetics, biology to clinical management. Main topics include genetic control, biology, growth factors, cell adhesion, cell motility and invasion, natures of bone metastasis, sentinel node therapies, hormonal links, new biomarkers and detection of micrometastasis and diagnosis. This timely book also covers the current treatment options.
Breast Cancer Metastasis And Drug Resistance
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Author : Aamir Ahmad
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-08
Breast Cancer Metastasis And Drug Resistance written by Aamir Ahmad and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-08 with Medical categories.
This volume comprehensively covers recent prrogress in breast cancer research. In an effort to successfully treat breast cancer, it is imperative to a) fully understand the disease with all its heterogeneity, b) understand the factors that influence the metastasis of breast cancer to distant organs making it lethal and c) understand the underlying processes that lead to the phenomenon of drug-resistance making the disease particularly incurable. The book explores all of these issues, including the phenomenon of epithelial-mesenchymal-transition, cancer stem cells as well as microRNAs in an attempt to better understand the disease in connection to its heterogeneity/metastasis/drug-resistance as well as to propose novel signaling pathways for therapeutic intervention. The profiling of tumors to molecularly classify breast cancers is also investigated so that customized targeted therapies can be developed.
Holland Frei Cancer Medicine
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Author : Robert C. Bast, Jr.
language : en
Publisher: John Wiley & Sons
Release Date : 2017-03-10
Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-10 with Medical categories.
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Breast Cancer Metastasis And Drug Resistance
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Author : Aamir Ahmad
language : en
Publisher: Springer Nature
Release Date : 2019-08-27
Breast Cancer Metastasis And Drug Resistance written by Aamir Ahmad and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-27 with Medical categories.
Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.
Metastasis
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Author : Lalage Wakefield
language : en
Publisher: IOS Press
Release Date : 2007
Metastasis written by Lalage Wakefield and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Breast categories.
Metastasis is the most dreaded aspect of the carcinogenic process. More than ninety percent of all cancer deaths are attributable to the consequences of the primary tumor successfully colonizing distant organs. Unlike the situation with colon cancer, a patient with breast cancer can never be considered 'cured', since as many as a third of breast cancer patients who have apparently curative surgery for their primary tumors ultimately relapse with metastatic disease, sometimes decades later. Much effort is now devoted to understanding this process of metastasis, and finding ways to predict and prevent its occurrence.This publication covers recent advances in the field, specifically as they relate to breast cancer. The availability of new tools and technological approaches has prompted a reconsideration of the very definition of a metastasis. Furthermore, a number of commonly held myths are being explored and a new definition of a metastasis, with important implications for clinical staging, is being proposed. Also, a novel conceptual framework for cancer progression based on the system-level dynamics of regulatory networks is presented and the role of chemokines in mediating some of
Handbook Of Metastatic Breast Cancer Second Edition
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Author : Charles Swanton
language : en
Publisher: CRC Press
Release Date : 2011-11-14
Handbook Of Metastatic Breast Cancer Second Edition written by Charles Swanton and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-14 with Medical categories.
Recent developments with novel systemic drugs, palliative surgical techniques and diagnostic imaging have given hope for the treatment of patients whose breast cancer has spread beyond its primary tumour. Written by a team from leading cancer centers in Europe, including the UK's Royal Marsden Hospital, the Handbook of Metastatic Breast Cancer, Second Edition provides advanced scientific information and guidance on clinical problems associated with metastatic breast cancer.
Chemoresistance And Metastasis In Breast Cancer Molecular Mechanisms And Novel Clinical Strategies
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Author : Qifeng Yang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-18
Chemoresistance And Metastasis In Breast Cancer Molecular Mechanisms And Novel Clinical Strategies written by Qifeng Yang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-18 with Medical categories.
100 Questions Answers About Metastatic Breast Cancer
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Author : Lillie D. Shockney
language : en
Publisher: Jones & Bartlett Learning
Release Date : 2021-03-15
100 Questions Answers About Metastatic Breast Cancer written by Lillie D. Shockney and has been published by Jones & Bartlett Learning this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-15 with Medical categories.
The American Cancer Society estimates over 275,000 new breast cancer diagnoses in American women for 2020. No one with breast cancer needs to be alone in their fight against this disease. That's where this book and the authoritative information within can help. This unique book provides both doctor and patient perspectives and offers answers to the most asked questions by patients and their loved ones. What is metastatic breast cancer? How will my oncologist decide how to treat my metastatic breast cancer? What is targeted therapy? Along with the answers to these and other questions, this book provides information on diagnosis, treatment, living with metastatic breast cancer, hormonal therapy, coping strategies, and more.
Advanced Breast Cancer
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Author : Musa Mayer
language : en
Publisher: Patient-Centered Guides
Release Date : 1998
Advanced Breast Cancer written by Musa Mayer and has been published by Patient-Centered Guides this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with BREAST--CANCER--POPULAR WORKS. categories.
This book discusses the realities of metastatic breast cancer. All aspects of the disease are covered: gathering information; coping with recurrent disease; making treatment choices; communicating with health professionals; and discussing end of life issues. Inspirational stories from those who have been there are also featured.
Mirnas And Target Genes In Breast Cancer Metastasis
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Author : Seema Sethi
language : en
Publisher: Springer
Release Date : 2014-10-13
Mirnas And Target Genes In Breast Cancer Metastasis written by Seema Sethi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-13 with Medical categories.
This SpringerBrief gives the latest research on the role of miRNAs in breast cancer metastasis. MicroRNAs (miRNAs) are recently described small endogenous noncoding RNAs implicated in the posttranscriptional control of gene expression. These tiny molecules are involved in developmental, physiologic phenomenon as well as pathologic processes including cancers. In fact, miRNAs have emerged as critical regulators of cancer progression, invasion and metastasis. This is mainly because a single miRNA can affect several downstream genes and signaling pathways with oncogenic or tumor suppressor actions depending on the target genes affected. Due to this multimodal downstream signaling effects, these small endogenous molecules hold great promise in metastasis prevention and treatment. Modulating the activity of miRNAs can provide opportunities for novel cancer interventions. Targeting miRNAs could become a novel prognostic and therapeutic strategy to prevent the future development of metastasis. Thus, miRNAs could also serve as a potential targets for anti-metastatic therapy. The book explores how the expression of miRNAs in the primary tumor could be silenced using antagomirs (chemically modified anti-miRNA oligonucleotides), which could prevent the development of metastasis; whereas once metastasis develops then it could be treated with miRNA mimics for inducing its expression for the treatment. Therefore, development of miRNA-based prophylactic therapies could serve as precision and personalized medicine against future development of metastasis of breast and other cancers.