Metastatic Bone Disease


Metastatic Bone Disease
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Metastatic Bone Disease


Metastatic Bone Disease
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Author : Ingo J. Diel
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Metastatic Bone Disease written by Ingo J. Diel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


"Metastatic Bone Disease: Fundamental and Clinical Aspects" is an expanded version of a workshop on bone metastases which was held in Heidelberg, Germany, in April 1993. Bone metastases very often develop from malignant tumors and lead to complications which considerably diminish the quality of life of the patient. Bone pain, pathological fractures, and hypercalcemic syndrome should be recognized and treated ear- ly, so as to prevent any further morbidity and immobilizati- on. Antiosteolytic substances such as biophosphonate can supplement the established palliative and supportive thera- pies. Highly qualified basic researchers and clinicians in pathophysiology, diagnosis, and treatment of metastatic bone disease have contributed to this book, providing a good overview ofpresent knowledge and research. The book will be of interest not only to specialists, but also to any physi- cian interested in oncology.



Metastatic Bone Disease


Metastatic Bone Disease
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Author : R. Lor Randall
language : en
Publisher: Springer Nature
Release Date :

Metastatic Bone Disease written by R. Lor Randall and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.




Metastatic Bone Disease


Metastatic Bone Disease
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Author : R. Lor Randall
language : en
Publisher: Springer
Release Date : 2015-12-01

Metastatic Bone Disease written by R. Lor Randall and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-01 with Medical categories.


Providing an integrated approach to the diagnosis and management of patients with metastatic bone disease (MBD), this comprehensive text combines discussion of the pathobiology of the disease with the latest oncological and orthopedic treatment modalities. After opening with an examination of the epidemiology and impact of MBD, the biology of bone metastases are discussed, along with considerations of the tissue of origin. Evaluation, biopsy and medical therapy, including metabolic agents and bio targeting. The heart of the book presents oncological approaches (supportive, radiation and interventional) and principles of orthopedic surgical oncology, with subsequent chapters covering specific anatomy, from the pelvis to the lower extremity and the spine. Chapters on emerging surgical technology and future directions conclude the text and redefine an integrated approach to patient care. Taken together, Metastatic Bone Disease is an excellent resource for orthopedic surgeons and cancer specialists alike.



Bone Metastases


Bone Metastases
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Author : Vassilios Vassiliou
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-19

Bone Metastases written by Vassilios Vassiliou and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-19 with Medical categories.


The second edition of this book serves both as an introductory and reference book focusing on the field of metastatic bone disease. Featuring contributions from experts in the field, this volume describes the molecular and cellular mechanisms involved in the formation of bone metastases, presents the newer advances made in the understanding of the clinical picture and symptoms of patients, analyses the role of bone markers in research and clinical practice and deals with all aspects of imaging modalities applied for the detection and evaluation of bone metastases. Moreover, the use of all available treatment methods, such as radiotherapy, surgery and systemic treatments for the management of patients with metastatic bone disease is discussed in detail. Overall this volume presents a thorough overview of all aspects of metastatic bone disease and provides a comprehensive and concise information resource for researchers, oncologists, orthopaedic surgeons and clinicians dealing with patients with metastatic bone disease.



Diagnosis And Management Of Metastatic Bone Disease


Diagnosis And Management Of Metastatic Bone Disease
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Author : Franklin Hindson Sim
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 1988

Diagnosis And Management Of Metastatic Bone Disease written by Franklin Hindson Sim and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medical categories.




Bone Metastases


Bone Metastases
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Author : Robert D. Rubens
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Bone Metastases written by Robert D. Rubens and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Bone Metastases brings together the many recent developments that are gradually improving the prospects for patients with secondary involvement of the skeleton in a primary cancer elsewhere. The morbidity from bone metastases is extensive, and the palliative and supportive treatment that sufferers require for many months or even years constitutes a major health problem. A multidisciplinary approach is essential since a variety of specialists are involved: radiation and medical oncologists, general and orthopaedic surgeons, general physicians, radiologists and nuclear medicine physicians, symptom control and terminal care specialists. The book's editors, themselves authorities in the fields of oncology and bone disease respectively, have brought together experts from all these disciplines to provide comprehensive coverage of metastatic bone disease. They cover the biology and pathophysiology, hypercalcaemia, imaging, assessment of response to treatment, types of treatment (systemic, radiotherapy, surgery), and symptomatic and supportive care. Particularly new approaches included are magnetic resonance imaging, the assessment of skeletal response and isotope therapy.



Bone Metastasis


Bone Metastasis
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Author : Gurmit Singh
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-28

Bone Metastasis written by Gurmit Singh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-28 with Medical categories.


A state-of-the-art review of the molecular underpinnings of bone-seeking cancers, current treatment approaches for them, and future therapeutic strategies. The authors illuminate the role of various autocrine, paracrine, and immunological factors involved in the progression and establishment of bone metastases, highlighting the physiological processes that lead to bone degradation, pain, angiogenesis, and dysregulation of bone turnover. They also discuss the various strategies that appear to have promise and are currently deployed in treatment or are at the experimental stage.



Bone Metastases


Bone Metastases
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Author : Robert David Rubens
language : en
Publisher: Springer
Release Date : 1991-01-01

Bone Metastases written by Robert David Rubens and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-01-01 with Bone Neoplasms categories.




Metastatic Bone Disease


Metastatic Bone Disease
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Author : R. Coleman
language : en
Publisher: Parthenon Publishing
Release Date : 1992-06

Metastatic Bone Disease written by R. Coleman and has been published by Parthenon Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-06 with Bone and bones categories.




Textbook Of Bone Metastases


Textbook Of Bone Metastases
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Author : Claude Jasmin
language : en
Publisher: John Wiley & Sons
Release Date : 2005-09-27

Textbook Of Bone Metastases written by Claude Jasmin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-09-27 with Medical categories.


The epidemiological and clinical importance of bone metastases has long been recognised. For example, the incidence of bone metastases in breast and prostate cancers is 70%, whereas it is only 30 to 40% in metastatic lung cancer. In clinical terms, bone metastases have substantial negative effects on the patient's quality of life. Bone metastases have generally received insufficient attention because of the difficulty in quantifying them, which has left them outside the scope of therapeutic trials This textbook is the result of the remarkable progress made in the understanding of the molecular and cellular mechanisms involved in osteogenesis and osteolysis, and their development for therapeutic purposes. The treatment of malignant hypercalcaemia has also been revolutionised by the use of bisphosphonates. The Textbook of Bone Metastases presents a broad approach to recent progress in all fields related to bone metastases, ranging from epidemiology to the physiopathology of bone metastases and therapeutics. It provides a better understanding of recent advances and, more importantly, will give clinicians all the information needed to help them in the clinical and therapeutic management of patients with bone metastases.