Methods And Applications Of Statistics In Clinical Trials Volume 2
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Methods And Applications Of Statistics In Clinical Trials Volume 2
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Author : Narayanaswamy Balakrishnan
language : en
Publisher: John Wiley & Sons
Release Date : 2014-06-16
Methods And Applications Of Statistics In Clinical Trials Volume 2 written by Narayanaswamy Balakrishnan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-16 with Medical categories.
Methods and Applications of Statistics in Clinical Trials, Volume 2: Planning, Analysis, and Inferential Methods includes updates of established literature from the Wiley Encyclopedia of Clinical Trials as well as original material based on the latest developments in clinical trials. Prepared by a leading expert, the second volume includes numerous contributions from current prominent experts in the field of medical research. In addition, the volume features: • Multiple new articles exploring emerging topics, such as evaluation methods with threshold, empirical likelihood methods, nonparametric ROC analysis, over- and under-dispersed models, and multi-armed bandit problems • Up-to-date research on the Cox proportional hazard model, frailty models, trial reports, intrarater reliability, conditional power, and the kappa index • Key qualitative issues including cost-effectiveness analysis, publication bias, and regulatory issues, which are crucial to the planning and data management of clinical trials
Methods And Applications Of Statistics In Clinical Trials Volume 2
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Author : Narayanaswamy Balakrishnan
language : en
Publisher: John Wiley & Sons
Release Date : 2014-06-09
Methods And Applications Of Statistics In Clinical Trials Volume 2 written by Narayanaswamy Balakrishnan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-09 with Medical categories.
Methods and Applications of Statistics in Clinical Trials, Volume 2: Planning, Analysis, and Inferential Methods includes updates of established literature from the Wiley Encyclopedia of Clinical Trials as well as original material based on the latest developments in clinical trials. Prepared by a leading expert, the second volume includes numerous contributions from current prominent experts in the field of medical research. In addition, the volume features: • Multiple new articles exploring emerging topics, such as evaluation methods with threshold, empirical likelihood methods, nonparametric ROC analysis, over- and under-dispersed models, and multi-armed bandit problems • Up-to-date research on the Cox proportional hazard model, frailty models, trial reports, intrarater reliability, conditional power, and the kappa index • Key qualitative issues including cost-effectiveness analysis, publication bias, and regulatory issues, which are crucial to the planning and data management of clinical trials
Methods And Applications Of Statistics In Clinical Trials Volume 1
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Author : Narayanaswamy Balakrishnan
language : en
Publisher: John Wiley & Sons
Release Date : 2014-03-05
Methods And Applications Of Statistics In Clinical Trials Volume 1 written by Narayanaswamy Balakrishnan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-05 with Medical categories.
A complete guide to the key statistical concepts essential for the design and construction of clinical trials As the newest major resource in the field of medical research, Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs presents a timely and authoritative reviewof the central statistical concepts used to build clinical trials that obtain the best results. The referenceunveils modern approaches vital to understanding, creating, and evaluating data obtained throughoutthe various stages of clinical trial design and analysis. Accessible and comprehensive, the first volume in a two-part set includes newly-written articles as well as established literature from the Wiley Encyclopedia of Clinical Trials. Illustrating a variety of statistical concepts and principles such as longitudinal data, missing data, covariates, biased-coin randomization, repeated measurements, and simple randomization, the book also provides in-depth coverage of the various trial designs found within phase I-IV trials. Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs also features: Detailed chapters on the type of trial designs, such as adaptive, crossover, group-randomized, multicenter, non-inferiority, non-randomized, open-labeled, preference, prevention, and superiority trials Over 100 contributions from leading academics, researchers, and practitioners An exploration of ongoing, cutting-edge clinical trials on early cancer and heart disease, mother-to-child human immunodeficiency virus transmission trials, and the AIDS Clinical Trials Group Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs is an excellent reference for researchers, practitioners, and students in the fields of clinicaltrials, pharmaceutics, biostatistics, medical research design, biology, biomedicine, epidemiology,and public health.
Methods And Applications Of Statistics In Clinical Trials Volume 1 And Volume 2
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Author : Narayanaswamy Balakrishnan
language : en
Publisher: Wiley
Release Date : 2014-05-27
Methods And Applications Of Statistics In Clinical Trials Volume 1 And Volume 2 written by Narayanaswamy Balakrishnan and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-27 with Medical categories.
This set includes Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs & Methods and Applications of Statistics in Clinical Trials, Volume 2: Planning, Analysis, and Inferential Methods. Volume 1 Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs successfully upholds the goals of the Wiley Encyclopedia of Clinical Trials by combining both previously-published and newly developed contributions written by over 100 leading academics, researchers, and practitioners in a comprehensive, approachable format. The result is a succinct reference that unveils modern, cutting-edge approaches to acquiring and understanding data throughout the various stages of clinical trial design and analysis. Volume 2 Featuring newly-written material as well as established literature from the Wiley Encyclopedia of Clinical Trials, this book provides a timely and authoritative review of techniques for planning clinical trials as well as the necessary inferential methods for analyzing collected data. This comprehensive volume features established and newly-written literature on the key statistical principles and concepts for designing modern-day clinical trials, such as hazard ratio, flexible designs, confounding, covariates, missing data, and longitudinal data. Examples of ongoing, cutting-edge clinical trials from today's research such as early cancer & heart disease, mother to child human immunodeficiency virus transmission, women's health initiative dietary, and AIDS clinical trials are also explored.
Studyguide For Methods And Applications Of Statistics In Clinical Trials
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Author : Cram101 Textbook Reviews
language : en
Publisher: Cram101
Release Date : 2014-06-18
Studyguide For Methods And Applications Of Statistics In Clinical Trials written by Cram101 Textbook Reviews and has been published by Cram101 this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-18 with categories.
Never HIGHLIGHT a Book Again! Includes all testable terms, concepts, persons, places, and events. Cram101 Just the FACTS101 studyguides gives all of the outlines, highlights, and quizzes for your textbook with optional online comprehensive practice tests. Only Cram101 is Textbook Specific. Accompanies: 9781118304761. This item is printed on demand.
Nonparametric Analysis Of Univariate Heavy Tailed Data
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Author : Natalia Markovich
language : en
Publisher: John Wiley & Sons
Release Date : 2008-03-11
Nonparametric Analysis Of Univariate Heavy Tailed Data written by Natalia Markovich and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-11 with Mathematics categories.
Heavy-tailed distributions are typical for phenomena in complex multi-component systems such as biometry, economics, ecological systems, sociology, web access statistics, internet traffic, biblio-metrics, finance and business. The analysis of such distributions requires special methods of estimation due to their specific features. These are not only the slow decay to zero of the tail, but also the violation of Cramer’s condition, possible non-existence of some moments, and sparse observations in the tail of the distribution. The book focuses on the methods of statistical analysis of heavy-tailed independent identically distributed random variables by empirical samples of moderate sizes. It provides a detailed survey of classical results and recent developments in the theory of nonparametric estimation of the probability density function, the tail index, the hazard rate and the renewal function. Both asymptotical results, for example convergence rates of the estimates, and results for the samples of moderate sizes supported by Monte-Carlo investigation, are considered. The text is illustrated by the application of the considered methodologies to real data of web traffic measurements.
Robust Statistics
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Author : Peter J. Huber
language : en
Publisher: John Wiley & Sons
Release Date : 2004
Robust Statistics written by Peter J. Huber and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Mathematics categories.
The first systematic, book-length treatment of the subject. Begins with a general introduction and the formal mathematical background behind qualitative and quantitative robustness. Stresses concepts. Provides selected numerical algorithms for computing robust estimates, as well as convergence proofs. Tables contain quantitative robustness information for a variety of estimates.
Loss Models
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Author : Stuart A. Klugman
language : en
Publisher: John Wiley & Sons
Release Date : 2013-08-05
Loss Models written by Stuart A. Klugman and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-05 with Business & Economics categories.
An essential resource for constructing and analyzing advanced actuarial models Loss Models: Further Topics presents extended coverage of modeling through the use of tools related to risk theory, loss distributions, and survival models. The book uses these methods to construct and evaluate actuarial models in the fields of insurance and business. Providing an advanced study of actuarial methods, the book features extended discussions of risk modeling and risk measures, including Tail-Value-at-Risk. Loss Models: Further Topics contains additional material to accompany the Fourth Edition of Loss Models: From Data to Decisions, such as: Extreme value distributions Coxian and related distributions Mixed Erlang distributions Computational and analytical methods for aggregate claim models Counting processes Compound distributions with time-dependent claim amounts Copula models Continuous time ruin models Interpolation and smoothing The book is an essential reference for practicing actuaries and actuarial researchers who want to go beyond the material required for actuarial qualification. Loss Models: Further Topics is also an excellent resource for graduate students in the actuarial field.
The Oxford Handbook Of Quantitative Methods Vol 2 Statistical Analysis
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Author : Todd D. Little
language : en
Publisher: Oxford University Press
Release Date : 2013-02-01
The Oxford Handbook Of Quantitative Methods Vol 2 Statistical Analysis written by Todd D. Little and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-01 with Psychology categories.
Research today demands the application of sophisticated and powerful research tools. Fulfilling this need, The Oxford Handbook of Quantitative Methods is the complete tool box to deliver the most valid and generalizable answers to todays complex research questions. It is a one-stop source for learning and reviewing current best-practices in quantitative methods as practiced in the social, behavioral, and educational sciences. Comprising two volumes, this handbook covers a wealth of topics related to quantitative research methods. It begins with essential philosophical and ethical issues related to science and quantitative research. It then addresses core measurement topics before delving into the design of studies. Principal issues related to modern estimation and mathematical modeling are also detailed. Topics in the handbook then segway into the realm of statistical inference and modeling with chapters dedicated to classical approaches as well as modern latent variable approaches. Numerous chapters associated with longitudinal data and more specialized techniques round out this broad selection of topics. Comprehensive, authoritative, and user-friendly, this two-volume set will be an indispensable resource for serious researchers across the social, behavioral, and educational sciences.
Planning Construction And Statistical Analysis Of Comparative Experiments
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Author : Francis G. Giesbrecht
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-26
Planning Construction And Statistical Analysis Of Comparative Experiments written by Francis G. Giesbrecht and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-26 with Mathematics categories.
A valuable guide to conducting experiments and analyzing dataacross a wide range of applications Experimental design is an important component of the scientificmethod. This book provides guidance on planning efficientinvestigations. It compiles designs for a wide range ofexperimental situations not previously found in accessible form.Focusing on applications in the physical, engineering, biological,and social sciences, Planning, Construction, and StatisticalAnalysis of Comparative Experiments is a valuable guide todesigning experiments and correctly analyzing and interpreting theresults. The authors draw on their years of experience in theclassroom and as statistical consultants to research programs oncampus, in government, and in industry. The object is always tostrike the right balance between mathematical necessities andpractical constraints. Serving both as a textbook for students of intermediatestatistics and a hands-on reference for active researchers, thetext includes: A wide range of applications, including agricultural sciences,animal and biomedical sciences, and industrial engineeringstudies General formulas for estimation and hypothesis testing,presented in a unified and simplified manner Guidelines for evaluating the power and efficiency of designsthat are not perfectly balanced New developments in the design of fractional factorials withnon-prime numbers of levels in mixed-level fractionalfactorials Detailed coverage on the construction of plans and therelationship among categories of designs Thorough coverage of balanced, lattice, cyclic, and alphadesigns Strategies for sequences of fractional factorials Data sets and SAS® code on a companion web site An ideal handbook for the investigator planning a researchprogram, the text comes complete with detailed plans of experimentsand alternative approaches for added flexibility.