Methods For Monitoring Mitochondrial Functions During Pathogen Infection

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Methods For Monitoring Mitochondrial Functions During Pathogen Infection
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Author :
language : en
Publisher: Elsevier
Release Date : 2025-03-10
Methods For Monitoring Mitochondrial Functions During Pathogen Infection written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-10 with Science categories.
Methods for Monitoring Mitochondrial Functions During Pathogen Infection, Volume 194 in the Methods in Cell Biology series highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Mitochondrial Labeling with Fluorescent Proteins for Enhanced Morphological Characterization and Visualization of Intercellular Mitochondrial Transfer, Visualizing mitochondrial electron transport chain complexes and super-complexes during infection of human macrophages with Legionella pneumophila, Quantitative assessment of mitochondrial membrane potential in macrophages in sepsis, Quantification of mitochondrial reactive oxygen species in macrophages during sepsis, and much more.Additional chapters cover Quantification of intracellular and mitochondrial ATP content in macrophages during lipopolysaccharide-induced inflammatory response, Analysis of cytosolic mtDNA release during Staphylococcus Aureus infection, Monitoring mitochondria dynamics upon infection using a tomographic approach, A screening system to determine bacterial effects on MADCAM1 expression by high endothelial venule cells, Isolation of mitochondria from Mycobacteria infected cells, Monitoring mitochondrial localization of Mycobacterial proteins, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Cell Biology series - Includes the latest information on the topic of development, characterization, and applications in CAR T Cells
Mitochondrial Dysfunction
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Author : Lawrence H. Lash
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Mitochondrial Dysfunction written by Lawrence H. Lash and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.
Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.
Molecular Detection Of Human Parasitic Pathogens
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Author : Dongyou Liu
language : en
Publisher: CRC Press
Release Date : 2012-07-05
Molecular Detection Of Human Parasitic Pathogens written by Dongyou Liu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-05 with Medical categories.
Traditionally, laboratory identification of parasites has relied upon various phenotypic procedures that detect their morphological, biological, and immunological features. Because these procedures tend to be time-consuming and technically demanding, molecular methods based on nucleic acid amplification technologies have been increasingly utilized
The Charnolosome As A Novel Nanothereranostic Biomarker
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Author : Sushil Sharma
language : en
Publisher: Elsevier
Release Date : 2024-09-30
The Charnolosome As A Novel Nanothereranostic Biomarker written by Sushil Sharma and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-30 with Science categories.
The Charnolosome as a Novel Nanothereranostic Biomarker: Overcoming Future Challenges in Medicine provides an overview of the charnolosome and its potential as a biomarker of cell injury. Based on the author's original discovery of the charnoly body in the developing, undernourished rat cerebellar Purkinje neurons, this book delves into the potential for utilizing this mitochondria and lysosomal-derived intracellular organelle as a nanotheranostic biomarker to prevent and cure various diseases.The book discusses the cellular, molecular, genetic, and epigenetic mechanisms of charnolosomes and charnolosome-derived nano-vesicles. It also investigates the molecular mechanisms underlying auto-inflammatory, autoimmune, and infectious diseases resulting from their compromised mitochondrial bioenergetics, and the potential use of the charnolosome in preventing and curing such conditions. - Shares the latest knowledge on the charnolosome and charnolosome-derived nano-vesicles and their significance at a cellular and molecular level - Considers the charnolosome in relation to a range of conditions, including neurodegenerative, metabolic, and multi-drug resistant systemic diseases - Presents future perspectives of the charnolosome in personalized nanotheranostics
Diagnostic Advances In Precision Medicine And Drug Development
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Author : Emmanuel Kwaku Ofori
language : en
Publisher: CRC Press
Release Date : 2025-06-18
Diagnostic Advances In Precision Medicine And Drug Development written by Emmanuel Kwaku Ofori and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-18 with Medical categories.
To arrive at the most appropriate decision regarding patient management, an essential step for medical practitioners is to determine a correct and accurate diagnosis of the patient’s condition. In recent years there have been significant technological efforts in chemistry, biochemistry, laboratory science, and biotechnology toward improving disease diagnosis and management in patients. Further, drug developers have utilized some of these novel diagnostic methods during preclinical and clinical trials that have led to creating efficiencies in their development processes. This book provides an overview of diagnostic procedures that aid in precision medicine and the drug development process. Presents innovative methodologies for diagnostic testing that will be beneficial to biomedical science researchers and health professionals Discusses recent significant technological advancement toward improving disease diagnosis Describes recent developments in spectroscopic and chromatographic methods that will be of interest to pharma companies and scientists in chemistry, biochemistry and pharmacology Gives an overview of the integration of artificial intelligence in digital health that will be beneficial to biotechnologists, bioengineers, health professionals and people in regulatory agencies Is suitable globally for graduate and postgraduate students studying laboratory medicine
Bibliography Of Agriculture
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Author :
language : en
Publisher:
Release Date : 1976
Bibliography Of Agriculture written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Agriculture categories.
T Cell Activation
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Author : Björn-Philipp Diercks
language : en
Publisher: Springer Nature
Release Date : 2025-04-12
T Cell Activation written by Björn-Philipp Diercks and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-12 with Science categories.
This volume provides detailed, up-to-date methods used in basic and applied research on T-cell activation. Chapters explore the fundamentals in T-cell biology a board range cutting-edge techniques from initial Ca2+ live-cell imaging to downstream effector functions in autoimmune disease. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, T- cell activation: Methods and Protocols will be an indispensable protocol collection for researchers studying T-cell activation in inflammation and immunity.
Mitochondria And Bacterial Pathogens Part B
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-05-31
Mitochondria And Bacterial Pathogens Part B written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-31 with Science categories.
Mitochondria and Bacterial Pathogens, Part B, Volume 375 discusses different pathogenic mechanisms that converge on the ability of bacteria to control the mitochondrial compartment of host cells. Chapters in this new release include Interaction between host cell mitochondria and Coxiella Burnetii, Control of mitochondrial functions by Pseudomonas aeruginosa in cystic fibrosis, Mitochondrial and bacterial ATP synthase: Structural similarities and divergences to exploit in the battle against M. tuberculosis, Role of mitochondria in the enteropathogenic Escherichia coli disease, Mitochondria dynamics and antibiotic resistance, and more. - Provides a collection of articles reporting on the role of mitochondria during bacterial infection - Covers Mitochondria, the evolutionary successors of an ancient endosymbiotic prokaryote, occupy a central position in the biology of modern eukaryotic cells - Includes content on numerous pathogenic bacteria and how they have evolved strategies to subvert the mitochondrial functions of host cells in support of proliferation and dissemination
Chemical Abstracts
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Author :
language : en
Publisher:
Release Date : 2002
Chemical Abstracts written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Chemistry categories.
The Role Of Autophagy In Infectious Diseases
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Author : Hua Niu
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-08
The Role Of Autophagy In Infectious Diseases written by Hua Niu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-08 with Science categories.