Methods Of Development Of New Anticancer Drugs

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Handbook Of Anticancer Drug Development
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Author : Daniel Budman
language : en
Publisher: Lippincott Raven
Release Date : 2003
Handbook Of Anticancer Drug Development written by Daniel Budman and has been published by Lippincott Raven this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Medical categories.
Perhaps no area of pharmacology has progressed further or faster than that of anticancer drugs. With this concise and informative resource, you'll explore the full spectrum of anticancer drug evolution -- from research and development, through clinical trials, to licensure and utilization.
Clinical Evaluation Of Antitumor Therapy
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Author : Franco M. Muggia
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Clinical Evaluation Of Antitumor Therapy written by Franco M. Muggia and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The methodology of drug development has been the subject of extensive dis cussion by a relatively small group of individuals in industry and government who have been intimately concerned with the identification and study of new anticancer drugs. The Chemotherapy Program of the National Cancer In stitute has represented the major focus of initial efforts in drug development, as summarized in the historical perspective presented in chapter 1 and its references. It is no coincidence that the Chemotherapy Program was the origin of the Division of Cancer Treatment, a government entity that has had a pivotal role in the growth of clinical oncology. In an analogous fashion this book presents the methodology employed in the clinical study of anticancer drugs within the broad context of cancer treatment. The research orientation promulgated in the study of new drugs is a central theme in most oncolo gists' approach to the clinical problem of cancer. Therefore, we hope that this book will introduce readers to treatment research in clinical oncology. For the oncologist, the clinical evaluation of antitumor therapy is both part of the day-to-day management of specific patients and the critical considera tion of developing therapeutic alternatives. For physicians in other fields of medicine it is important to acquaint themselves with the basic tools of the oncologist. For people without medical training, including patients who might be interested in treatment research, many of the chapters may be overly technical.
Biomedical Index To Phs Supported Research
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Author :
language : en
Publisher:
Release Date : 1993
Biomedical Index To Phs Supported Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medicine categories.
Biomedical Index To Phs Supported Research Pt A Subject Access A H
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Author :
language : en
Publisher:
Release Date : 1992
Biomedical Index To Phs Supported Research Pt A Subject Access A H written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medicine categories.
Cancer Treatment Reports
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Author :
language : en
Publisher:
Release Date : 1980
Cancer Treatment Reports written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Cancer categories.
The Story Of Taxol
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Author : Jordan Goodman
language : en
Publisher: Cambridge University Press
Release Date : 2001-03-05
The Story Of Taxol written by Jordan Goodman and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-03-05 with Health & Fitness categories.
Taxol is arguably the most celebrated, talked-about and controversial natural product in recent years. It is celebrated because of its efficacy as an anti-cancer drug and because its discovery has provided powerful support for policies concerned with biodiversity; talked about because in the late 1980s and early 1990s the American public was bombarded with news reports and special programmes about the molecule and its host, the Pacific yew; and controversial because during the early 1990s the drug and the tree became embroiled in a number of very sensitive political issues with wide implications for the conduct of public policy. The Story of Taxol tells this story.
Chemistry And Pharmacology Of Anticancer Drugs
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Author : David E. Thurston
language : en
Publisher: CRC Press
Release Date : 2021-03-18
Chemistry And Pharmacology Of Anticancer Drugs written by David E. Thurston and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-18 with Medical categories.
While drug therapies developed in the last 80 years have markedly improved treatment outcomes and the management of some types of cancers, the lack of effectiveness and side effects associated with the most common treatment types remain unacceptable. However, recent technological advances are leading to improved therapies based on targeting distinct biological pathways in cancer cells. Chemistry and Pharmacology of Anticancer Drugs is a comprehensive survey of all families of anticancer agents and therapeutic approaches currently in use or in advanced stages of clinical trials, including biological-based therapies. The book is unique in providing molecular structures for all anticancer agents, discussing them in terms of history of development, chemistry, mechanism of action, structure–function relationships, and pharmacology. It also provides relevant information on side effects, dosing, and formulation. The authors, renowned scientists in cancer research and drug discovery, also provide up-to-date information on the drug discovery process, including discussions of new research tools, tumor-targeting strategies, and fundamental concepts in the relatively new areas of precision medicine and chemoprevention. Chemistry and Pharmacology of Anticancer Drugs is an indispensable resource for cancer researchers, medicinal chemists and other biomedical scientists involved in the development of new anticancer therapies. Its breadth of coverage, clear explanations, and illustrations also make it suitable for undergraduate and postgraduate courses in medicine, pharmacy, nursing, dentistry, nutrition, the biomedical sciences, and related disciplines. Key Features: Summarizes the fundamental causes of cancer, modes of treatment, and strategies for cancer drug discovery Brings together a broad spectrum of information relating to the chemistry and pharmacology of all families of anticancer agents and therapies Includes up-to-date information on cutting-edge aspects of cancer treatments such as biomarkers, pharmacogenetics, and pharmacogenomics Features new chapters on the "Evolution of Anticancer Therapies", "Antibody-Based Therapies", and "Cancer Chemoprevention"
In Vitro Bioassay Techniques For Anticancer Drug Discovery And Development
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Author : Dhanya Sunil
language : en
Publisher: CRC Press
Release Date : 2022-07-12
In Vitro Bioassay Techniques For Anticancer Drug Discovery And Development written by Dhanya Sunil and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-12 with categories.
This comprehensive and useful handbook represents a definitive up-to-date compendium of key in vitro bioassay methods that are employed to quantify and validate the anticancer activity of a drug candidate before it makes its way into animal or clinical trials. In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development covers the screening and evaluation of potential drug candidates in a wide category of anticancer assays demonstrating the specific ways in which various pharmaceutical bioassays interpret the activity of drug molecules. The major emphasis of the book is to present those bioassays which can be readily set up and practiced in any laboratory with limited funds, facilities, or technical know-how. Key Features, Provides a user-friendly, one-stop, comprehensive and coherent foundation for in vitro anticancer drug development, An essential guide to young investigators starting a program on natural resources in the anticancer area from biodiversity-rich countries, This handbook presents old and new protocols that are relevant for cancer drug screening, The reader is offered an insight into the intricate processes in drug discovery and the importance and role of in vitro bioassays for screening compounds and their specific applications in the assessment of therapies for cancer, Useful for any pharmaceutical researcher or medicinal chemist researching the principles behind clinically relevant methods, ideas, and techniques in this field Book jacket.
Methods Of Development Of New Anticancer Drugs
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Author : Joseph Francis Saunders
language : en
Publisher:
Release Date : 1977
Methods Of Development Of New Anticancer Drugs written by Joseph Francis Saunders and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Cancer categories.
Annual Report
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Author : National Cancer Institute (U.S.). Division of Cancer Treatment
language : en
Publisher:
Release Date : 1982
Annual Report written by National Cancer Institute (U.S.). Division of Cancer Treatment and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Cancer categories.