Methods Of Randomization In Experimental Design

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Randomization In Clinical Trials

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Author : William F. Rosenberger
language : en
Publisher: John Wiley & Sons
Release Date : 2015-11-23

Randomization In Clinical Trials written by William F. Rosenberger and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-23 with Mathematics categories.

Praise for the First Edition “All medical statisticians involved in clinical trials should read this book...” - Controlled Clinical Trials Featuring a unique combination of the applied aspects of randomization in clinical trials with a nonparametric approach to inference, Randomization in Clinical Trials: Theory and Practice, Second Edition is the go-to guide for biostatisticians and pharmaceutical industry statisticians. Randomization in Clinical Trials: Theory and Practice, Second Edition features: Discussions on current philosophies, controversies, and new developments in the increasingly important role of randomization techniques in clinical trials A new chapter on covariate-adaptive randomization, including minimization techniques and inference New developments in restricted randomization and an increased focus on computation of randomization tests as opposed to the asymptotic theory of randomization tests Plenty of problem sets, theoretical exercises, and short computer simulations using SAS® to facilitate classroom teaching, simplify the mathematics, and ease readers’ understanding Randomization in Clinical Trials: Theory and Practice, Second Edition is an excellent reference for researchers as well as applied statisticians and biostatisticians. The Second Edition is also an ideal textbook for upper-undergraduate and graduate-level courses in biostatistics and applied statistics. William F. Rosenberger, PhD, is University Professor and Chairman of the Department of Statistics at George Mason University. He is a Fellow of the American Statistical Association and the Institute of Mathematical Statistics, and author of over 80 refereed journal articles, as well as The Theory of Response-Adaptive Randomization in Clinical Trials, also published by Wiley. John M. Lachin, ScD, is Research Professor in the Department of Epidemiology and Biostatistics as well as in the Department of Statistics at The George Washington University. A Fellow of the American Statistical Association and the Society for Clinical Trials, Dr. Lachin is actively involved in coordinating center activities for clinical trials of diabetes. He is the author of Biostatistical Methods: The Assessment of Relative Risks, Second Edition, also published by Wiley.

Encyclopedia Of Research Design

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Author : Neil J. Salkind
language : en
Publisher: SAGE
Release Date : 2010-06-22

Encyclopedia Of Research Design written by Neil J. Salkind and has been published by SAGE this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-22 with Philosophy categories.

"Comprising more than 500 entries, the Encyclopedia of Research Design explains how to make decisions about research design, undertake research projects in an ethical manner, interpret and draw valid inferences from data, and evaluate experiment design strategies and results. Two additional features carry this encyclopedia far above other works in the field: bibliographic entries devoted to significant articles in the history of research design and reviews of contemporary tools, such as software and statistical procedures, used to analyze results. It covers the spectrum of research design strategies, from material presented in introductory classes to topics necessary in graduate research; it addresses cross- and multidisciplinary research needs, with many examples drawn from the social and behavioral sciences, neurosciences, and biomedical and life sciences; it provides summaries of advantages and disadvantages of often-used strategies; and it uses hundreds of sample tables, figures, and equations based on real-life cases."--Publisher's description.

Methods Of Randomization In Experimental Design

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Author : Valentim R. Alferes
language : en
Publisher: SAGE Publications
Release Date : 2012-10-01

Methods Of Randomization In Experimental Design written by Valentim R. Alferes and has been published by SAGE Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-01 with Social Science categories.

In Methods of Randomization in Experimental Design, author Valentim R. Alferes presents the main procedures of random assignment and local control in between-subjects experimental designs and the counterbalancing schemes in within-subjects or cross-over experimental designs. Alferes uses a pedagogical strategy that allows the reader to implement all randomization methods by relying on the materials given in the appendices and using common features included in most word processor software. A companion website at www.sagepub.com/alferes provides downloadable IBM SPSS and R versions of SCRAED, a package that performs simple and complex random assignment in experimental design, including the 18 randomization methods presented in Chapters 2 and 3.

Good Research Practice In Non Clinical Pharmacology And Biomedicine

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Author : Anton Bespalov
language : en
Publisher: Springer Nature
Release Date : 2020-02-20

Good Research Practice In Non Clinical Pharmacology And Biomedicine written by Anton Bespalov and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-20 with Medical categories.

This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.

Handbook Of Statistical Methods For Randomized Controlled Trials

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Author : KyungMann Kim
language : en
Publisher: CRC Press
Release Date : 2021-08-23

Handbook Of Statistical Methods For Randomized Controlled Trials written by KyungMann Kim and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-23 with Mathematics categories.

Statistical concepts provide scientific framework in experimental studies, including randomized controlled trials. In order to design, monitor, analyze and draw conclusions scientifically from such clinical trials, clinical investigators and statisticians should have a firm grasp of the requisite statistical concepts. The Handbook of Statistical Methods for Randomized Controlled Trials presents these statistical concepts in a logical sequence from beginning to end and can be used as a textbook in a course or as a reference on statistical methods for randomized controlled trials. Part I provides a brief historical background on modern randomized controlled trials and introduces statistical concepts central to planning, monitoring and analysis of randomized controlled trials. Part II describes statistical methods for analysis of different types of outcomes and the associated statistical distributions used in testing the statistical hypotheses regarding the clinical questions. Part III describes some of the most used experimental designs for randomized controlled trials including the sample size estimation necessary in planning. Part IV describe statistical methods used in interim analysis for monitoring of efficacy and safety data. Part V describe important issues in statistical analyses such as multiple testing, subgroup analysis, competing risks and joint models for longitudinal markers and clinical outcomes. Part VI addresses selected miscellaneous topics in design and analysis including multiple assignment randomization trials, analysis of safety outcomes, non-inferiority trials, incorporating historical data, and validation of surrogate outcomes.

Methods In Psychological Research

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Author : Bryan J. Rooney
language : en
Publisher: SAGE Publications
Release Date : 2018-08-01

Methods In Psychological Research written by Bryan J. Rooney and has been published by SAGE Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-01 with Psychology categories.

Methods in Psychological Research introduces students to the rich world of research in psychology through student-friendly writing, compelling real-world examples, and frequent opportunities for practice. Using a relaxed yet supportive tone that eases student anxiety, authors Bryan J. Rooney and Annabel Ness Evans present a mixture of conceptual and practical discussions, and spark reader interest in research by covering meaningful topics that resonate with today’s students. In-text features like Conceptual Exercises, FYI sections, and FAQ sections with accompanying visual cues support learning throughout the research experience. The Fourth Edition equips students with the tools they need to understand research concepts, conduct their own experiments, and present their findings.

Field Trials Of Health Interventions

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Author : Peter G. Smith
language : en
Publisher:
Release Date : 2015

Field Trials Of Health Interventions written by Peter G. Smith and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Health & Fitness categories.

This is an open access title available under the terms of a CC BY-NC 4.0 International licence. It is free to read at Oxford Scholarship Online and offered as a free PDF download from OUP and selected open access locations. Before new interventions are released into disease control programmes, it is essential that they are carefully evaluated in field trials'. These may be complex and expensive undertakings, requiring the follow-up of hundreds, or thousands, of individuals, often for long periods. Descriptions of the detailed procedures and methods used in the trials that have been conducted have rarely been published. A consequence of this, individuals planning such trials have few guidelines available and little access to knowledge accumulated previously, other than their own. In this manual, practical issues in trial design and conduct are discussed fully and in sufficient detail, that Field Trials of Health Interventions may be used as a toolbox' by field investigators. It has been compiled by an international group of over 30 authors with direct experience in the design, conduct, and analysis of field trials in low and middle income countries and is based on their accumulated knowledge and experience. Available as an open access book via Oxford Medicine Online, this new edition is a comprehensive revision, incorporating the new developments that have taken place in recent years with respect to trials, including seven new chapters on subjects ranging from trial governance, and preliminary studies to pilot testing.

The Sage Encyclopedia Of Communication Research Methods

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Author : Mike Allen
language : en
Publisher: SAGE Publications
Release Date : 2017-04-11

The Sage Encyclopedia Of Communication Research Methods written by Mike Allen and has been published by SAGE Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-11 with Social Science categories.

Communication research is evolving and changing in a world of online journals, open-access, and new ways of obtaining data and conducting experiments via the Internet. Although there are generic encyclopedias describing basic social science research methodologies in general, until now there has been no comprehensive A-to-Z reference work exploring methods specific to communication and media studies. Our entries, authored by key figures in the field, focus on special considerations when applied specifically to communication research, accompanied by engaging examples from the literature of communication, journalism, and media studies. Entries cover every step of the research process, from the creative development of research topics and questions to literature reviews, selection of best methods (whether quantitative, qualitative, or mixed) for analyzing research results and publishing research findings, whether in traditional media or via new media outlets. In addition to expected entries covering the basics of theories and methods traditionally used in communication research, other entries discuss important trends influencing the future of that research, including contemporary practical issues students will face in communication professions, the influences of globalization on research, use of new recording technologies in fieldwork, and the challenges and opportunities related to studying online multi-media environments. Email, texting, cellphone video, and blogging are shown not only as topics of research but also as means of collecting and analyzing data. Still other entries delve into considerations of accountability, copyright, confidentiality, data ownership and security, privacy, and other aspects of conducting an ethical research program. Features: 652 signed entries are contained in an authoritative work spanning four volumes available in choice of electronic or print formats. Although organized A-to-Z, front matter includes a Reader’s Guide grouping entries thematically to help students interested in a specific aspect of communication research to more easily locate directly related entries. Back matter includes a Chronology of the development of the field of communication research; a Resource Guide to classic books, journals, and associations; a Glossary introducing the terminology of the field; and a detailed Index. Entries conclude with References/Further Readings and Cross-References to related entries to guide students further in their research journeys. The Index, Reader’s Guide themes, and Cross-References combine to provide robust search-and-browse in the e-version.

The Design And Statistical Analysis Of Animal Experiments

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Author : Simon T. Bate
language : en
Publisher: Cambridge University Press
Release Date : 2014-03-13

The Design And Statistical Analysis Of Animal Experiments written by Simon T. Bate and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-13 with Computers categories.

This book will provide scientists with a better understanding of statistics, improving their decision-making and reducing animal use.

Experimental And Quasi Experimental Designs For Research

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Author : Donald T. Campbell
language : en
Publisher: Ravenio Books
Release Date : 2015-09-03

Experimental And Quasi Experimental Designs For Research written by Donald T. Campbell and has been published by Ravenio Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-03 with Psychology categories.

We shall examine the validity of 16 experimental designs against 12 common threats to valid inference. By experiment we refer to that portion of research in which variables are manipulated and their effects upon other variables observed. It is well to distinguish the particular role of this chapter. It is not a chapter on experimental design in the Fisher (1925, 1935) tradition, in which an experimenter having complete mastery can schedule treatments and measurements for optimal statistical efficiency, with complexity of design emerging only from that goal of efficiency. Insofar as the designs discussed in the present chapter become complex, it is because of the intransigency of the environment: because, that is, of the experimenter’s lack of complete control.