Microbial Comparative Genomics And Pangenomics New Tools Approaches And Insights Into Gene And Genome Evolution
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Microbial Comparative Genomics And Pangenomics New Tools Approaches And Insights Into Gene And Genome Evolution
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Author : Paulo Jorge Dias
language : en
Publisher: Frontiers Media SA
Release Date : 2024-11-11
Microbial Comparative Genomics And Pangenomics New Tools Approaches And Insights Into Gene And Genome Evolution written by Paulo Jorge Dias and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-11 with Science categories.
Comparative Genomics is the field of knowledge dedicated to the analysis and comparison of genes and genomes. The scientific areas comprised in this field include subjects as diverse as (just naming a few): 1) the development of algorithms for the alignment of genes, whole genomes, short- and long sequencing reads, 2) the search for remote sequence similarity, 3) the discovery of motifs and sequence patterns, 4) the identification of gene families, 5) the detection of ortholog/paralog groups, 6) the reconstruction of evolutionary history of the genes, 7) the detection of signs of selective forces exerted over genes and genomes, 8) the reconstruction of ancestral DNA and genome sequences, 9) the detection and analysis of genome synteny, 10) the inference of ancestral gene order, among others. In addition, an important new sub-field of Comparative Genomics has emerged in the last decade, referred to as Pangenomics, making available improved tools to analyze the exponential genomic data accumulating since the development of Second- and Third-Generation Sequencing Technologies.
Pan Genomics Applications Challenges And Future Prospects
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Author : Debmalya Barh
language : en
Publisher: Academic Press
Release Date : 2020-03-06
Pan Genomics Applications Challenges And Future Prospects written by Debmalya Barh and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-06 with Science categories.
Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches, brings the main concepts and current approaches on pan-genomics research; the second, "case studies in pan-genomics, thoroughly discusses twelve case, and the last, "current approaches and future prospects in pan-multiomics, encompasses the developments on omics studies to be applied on bacteria related studies. This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health. - Covers the entire spectrum of pangenomics, highlighting the use of specific approaches, case studies and future perspectives - Discusses current bioinformatics tools and strategies for exploiting pangenomics data - Presents twelve case studies with different organisms in order to provide the audience with real examples of pangenomics applicability
The Pangenome
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Author : Hervé Tettelin
language : en
Publisher: Springer Nature
Release Date : 2020-04-30
The Pangenome written by Hervé Tettelin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-30 with Science categories.
This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.
Computational Genomics And Structural Bioinformatics In Microbial Science
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Author : Javid Ahmad Parray
language : en
Publisher: Academic Press
Release Date : 2025-02-24
Computational Genomics And Structural Bioinformatics In Microbial Science written by Javid Ahmad Parray and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-24 with Science categories.
Computational Genomics and Structural Bioinformatics in Microbial Science: Microbial Genomics (Volume 2) covers different aspects of microbial genomics, metagenomics, and functional studies of microbes through informative illustrations of current trends in computational tools and bioinformatics approach in environmental microbiology and clinical diagnosis. This book aims to provide readers with an overview of the microbial genome, computational genomics, and structural bioinformatics in microbial science, as well as the most recent developments in these fields. This book covers a range of topics, including the challenges and opportunities of computational epigenomics, bioinformatics tools for assessing metagenomic data, as well as computed comparative genomics and computational phenotyping of microorganisms relevant to agriculture. Microbial Genomics: Host Adaptation, virulence, and Evolution is a valuable resource for faculty members, researchers, and undergraduate and postgraduate students at universities, medical research labs, that are interested in microbial science specifically related to the microbial genome, computing genomics, and bioinformatics. - Provides informative illustrations of current trends in computational tools and bioinformatics approach - Presents bioinformatics of next generation sequencing in clinical microbiology diagnosis - Discusses structural bioinformatics and its applications
Phylogenomics
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Author : Rob DeSalle
language : en
Publisher: CRC Press
Release Date : 2020-08-18
Phylogenomics written by Rob DeSalle and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-18 with Computers categories.
Phylogenomics: A Primer, Second Edition is for advanced undergraduate and graduate biology students studying molecular biology, comparative biology, evolution, genomics, and biodiversity. This book explains the essential concepts underlying the storage and manipulation of genomics level data, construction of phylogenetic trees, population genetics, natural selection, the tree of life, DNA barcoding, and metagenomics. The inclusion of problem-solving exercises in each chapter provides students with a solid grasp of the important molecular and evolutionary questions facing modern biologists as well as the tools needed to answer them.
Population And Comparative Genomics Of Plant Pathogenic Bacteria
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Author : Jeffrey Jones
language : en
Publisher: Frontiers Media SA
Release Date : 2022-09-02
Population And Comparative Genomics Of Plant Pathogenic Bacteria written by Jeffrey Jones and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-02 with Science categories.
The Pangenome
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Author : Hervé Tettelin
language : en
Publisher:
Release Date : 2020-10-09
The Pangenome written by Hervé Tettelin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-09 with Science categories.
This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book's respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Evolutionary Genomics
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Author : Maria Anisimova
language : en
Publisher: Humana Press
Release Date : 2012-03-08
Evolutionary Genomics written by Maria Anisimova and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-08 with Medical categories.
Together with early theoretical work in population genetics, the debate on sources of genetic makeup initiated by proponents of the neutral theory made a solid contribution to the spectacular growth in statistical methodologies for molecular evolution. Evolutionary Genomics: Statistical and Computational Methods is intended to bring together the more recent developments in the statistical methodology and the challenges that followed as a result of rapidly improving sequencing technologies. Presented by top scientists from a variety of disciplines, the collection includes a wide spectrum of articles encompassing theoretical works and hands-on tutorials, as well as many reviews with key biological insight. Volume 2 begins with phylogenomics and continues with in-depth coverage of natural selection, recombination, and genomic innovation. The remaining chapters treat topics of more recent interest, including population genomics, -omics studies, and computational issues related to the handling of large-scale genomic data. Written in the highly successful Methods in Molecular BiologyTM series format, this work provides the kind of advice on methodology and implementation that is crucial for getting ahead in genomic data analyses. Comprehensive and cutting-edge, Evolutionary Genomics: Statistical and Computational Methods is a treasure chest of state-of the-art methods to study genomic and omics data, certain to inspire both young and experienced readers to join the interdisciplinary field of evolutionary genomics.
Insights On Plant Associated Microorganisms Diversity Systematics And Genomics
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Author : James T. Tambong
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-16
Insights On Plant Associated Microorganisms Diversity Systematics And Genomics written by James T. Tambong and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-16 with Science categories.
Computational Biology And Chemistry
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Author : Payam Behzadi
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-12
Computational Biology And Chemistry written by Payam Behzadi and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12 with Science categories.
The use of computers and software tools in biochemistry (biology) has led to a deep revolution in basic sciences and medicine. Bioinformatics and systems biology are the direct results of this revolution. With the involvement of computers, software tools, and internet services in scientific disciplines comprising biology and chemistry, new terms, technologies, and methodologies appeared and established. Bioinformatic software tools, versatile databases, and easy internet access resulted in the occurrence of computational biology and chemistry. Today, we have new types of surveys and laboratories including "in silico studies" and "dry labs" in which bioinformaticians conduct their investigations to gain invaluable outcomes. These features have led to 3-dimensioned illustrations of different molecules and complexes to get a better understanding of nature.