Microbial Genomics And Drug Discovery
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Microbial Genomics And Drug Discovery
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Author : Thomas J. Dougherty
language : en
Publisher: CRC Press
Release Date : 2003-05-14
Microbial Genomics And Drug Discovery written by Thomas J. Dougherty and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-05-14 with Medical categories.
Exploring innovative routes of drug discovery in the postgenomic era, Microbial Genomics and Drug Discovery examines bioinformatic and genomic approaches for the identification, detection, selection, and validation of new antibacterial targets and vaccine candidates. The book discusses potential pathways for effective infection control, inhibition of antibacterial resistance, and acceleration of the drug discovery process. This comprehensive reference describes procedures to recognize common targets in various bacterial species for the design of broad-spectrum antibiotics and clearly illustrates the use of pathway tools in a genomics-based drug discovery project.
Microbial Genomes
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Author : Claire M. Fraser
language : en
Publisher: Humana Press
Release Date : 2010-12-09
Microbial Genomes written by Claire M. Fraser and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-09 with Science categories.
This collection of diverse articles by the pioneers of modern genomics takes stock of the current state of the field and elucidates the contribution that sequencing genomes has made to our understanding of microbial metabolism and evolution. Through twenty-eight thought-provoking chapters, the authors describe some of the most common computational methods and their applications to studying pathogenic microorganisms, show how genomics can be used to reconstruct the history and dynamism of the microbial world, and discuss issues as diverse as reconstruction of metabolic pathways, cell cycle processes, microbial evolution, metagenomics, and vaccine development. Additional chapters deal with microarrays and expression analysis and the role of genomic in drug discovery.
Microbial Resources
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Author : Ipek Kurtböke
language : en
Publisher: Academic Press
Release Date : 2017-03-31
Microbial Resources written by Ipek Kurtböke and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-31 with Medical categories.
Microbial Resources: From Functional Existence in Nature to Applications provides an exciting interdisciplinary journey through the rapidly developing field of microbial resources, including relationships to aspects of microbiology. Covers the functional existence of microorganisms in nature, as well as the transfer of this knowledge for industrial and other applications. Examines the economic perspective of revealing the potential value of microbial material and figuring it into socio-economic value; legal perspectives; and how to organize a fair allotment of socio-economic benefits to all stakeholders who have effectively contributed to the preservation, study, and exploitation of microbiological material. Covers aspects of foundational information related to microbiology, microbial ecology, and diversity, as well as new advances in microbial genomics Provides information on the utilization of microbial resources in biotechnology Covers legislative issues and related law in biodiscovery Fills a need for a very broad audience and is a good resource for microbiologists seeking to know the extent of microbiology approaches, the policies associated with microbiology, and potential career paths for researchers Has significant added value due to the inclusion of comprehensive coverage of the biology, ecology, biochemistry and international legislation surrounding these applications
Microbial Functional Genomics
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Author : Jizhong Zhou
language : en
Publisher: John Wiley & Sons
Release Date : 2004-03-19
Microbial Functional Genomics written by Jizhong Zhou and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-03-19 with Science categories.
Microbial Functional Genomics offers a timely summary of the principles, approaches, and applications. It presents a comprehensive review of microbial functional genomics, covering microbial diversity, microbial genome sequencing, genomic technologies, genome-wide functional analysis, applied functional genomics, and future directions. An introduction will offer a definition of the field and an overview of the historical and comparative genomics aspects.
Marine Biotechnology In The Twenty First Century
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2002-05-29
Marine Biotechnology In The Twenty First Century written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-05-29 with Science categories.
Dramatic developments in understanding the fundamental underpinnings of life have provided exciting opportunities to make marine bioproducts an important part of the U.S. economy. Several marine based pharmaceuticals are under active commercial development, ecosystem health is high on the public's list of concerns, and aquaculture is providing an ever greater proportion of the seafood on our tables. Nevertheless, marine biotechnology has not yet caught the public's, or investor's, attention. Two workshops, held in October 1999 and November 2001 at the National Academies, were successful in highlighting new developments and opportunities in environmental and biomedical applications of marine biotechnology, and also in identifying factors that are impeding commercial exploitation of these products. This report includes a synthesis of the 2001 sessions addressing drug discovery and development, applications of genomics and proteomics to marine biotechnology, biomaterials and bioengineering, and public policy and essays contributed by the workshop speakers.
Pathogen Genomics
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Author : Karen Joy Shaw
language : en
Publisher:
Release Date : 2002-05-17
Pathogen Genomics written by Karen Joy Shaw and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-05-17 with categories.
Microbial Genomics Clinical Pharmaceutical And Industrial Applications
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Author : Huseyin Tombuloglu
language : en
Publisher: Academic Press
Release Date : 2024-05-01
Microbial Genomics Clinical Pharmaceutical And Industrial Applications written by Huseyin Tombuloglu and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-01 with Science categories.
Microbial Genomics: Clinical, Pharmaceutical and Industrial Applications focuses on the various applications of microbial genomics in clinical, pharmaceutical, and industrial fields. The book consists of four parts devoted to bacterial, viral, and fungal genomics, as well as their applications in clinical, pharmaceutical, and industrial fields. Chapters are written by experts in their respective disciplines and are tightly organized with an introduction to detailed descriptions, available software implementation, applications, advanced topics, summaries, analytic questions, exercises, and suggested readings. Throughout this book, the latest genomics and biotechnological developments and discoveries as well as open problems and future challenges on microbial genomics are highlighted. Readers will be introduced to state-of-the-art developments and trends of microbial genomics, its clinical, pharmaceutical, and industrial applications.
Post Genomic Approaches In Drug And Vaccine Development
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Author : Kishore R. Sakharkar
language : en
Publisher: CRC Press
Release Date : 2022-09-01
Post Genomic Approaches In Drug And Vaccine Development written by Kishore R. Sakharkar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-01 with Science categories.
Over the past decade, genome sequencing projects and the associated efforts have facilitated the discovery of several novel disease targets and the approval of several innovative drugs. To further exploit this data for human health and disease, there is a need to understand the genome data itself in detail, discover novel targets, understand their role in physiological pathways and associated diseases, with the aim to translate these discoveries to clinical and preventive medicine. It is equally important to understand the labors and limitations in integrating clinical phenotypes with genomic, transcriptomic, proteomic and metabolomic approaches. T
Frontiers In Anti Infective Drug Discovery Volume 8
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Author : Atta-ur-Rahman
language : en
Publisher: Bentham Science Publishers
Release Date : 2020-10-05
Frontiers In Anti Infective Drug Discovery Volume 8 written by Atta-ur-Rahman and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-05 with Medical categories.
This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The eighth volume of this series features 8 chapters that cover methods for antimicrobial drug discovery (with 2 chapters that focus on genomics) as well as updates on drug development against Helicobacter pylori and emerging coronaviruses, among other interesting topics: - Eradication of Helicobacter pylori Infection with Non-Bismuth Quadruple Concomitant Therapy - Drug Discovery Strategies Against Emerging Coronaviruses: A Global Threat - Opportunities Offered By Fragment-Based Drug Design in Antibiotic Development - Phage therapy as a Tool for Control of Foodborne Diseases: Advantages and Limitations - Subtractive Genomics Approaches: Towards Anti-Bacterial Drug Discovery - Recent Advances in the Discovery of Antimicrobials through Metagenomics - Phyto-Nano-Antimicrobials: Synthesis, Characterization, Discovery, and Advances - Aptamers as Anti-infective Agents.
Drug Resistance In Bacteria Fungi Malaria And Cancer
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Author : Gunjan Arora
language : en
Publisher: Springer
Release Date : 2017-03-21
Drug Resistance In Bacteria Fungi Malaria And Cancer written by Gunjan Arora and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-21 with Medical categories.
This book is a compilation of past and recent knowledge in the field of emerging drug resistance. The book covers major aspects of drug resistance in bacteria, fungi, malaria, and cancer.Human survival on earth is constantly threatened by disease and syndrome. From the early days, the aim of research in medicine was to find therapeutic agents that can improve the quality of human life. Although humans are dependent on natural compounds from early days their dependence of drugs increased excessively in last century. The advances in chemistry and biology have helped researchers to identify the drugs that have improved treatment of many diseases. The primary factor for treatment of these diseases is dependent on the efficacy of drugs available. The development of resistance to these drugs is one of the major hindrances. Although there are number of books available on this topic, “drug resistance” biology across kingdoms has never been discussed in a coherent way.