Microdialysis In The Neurosciences

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Microdialysis In The Neurosciences

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Author : T.E. Robinson
language : en
Publisher: Elsevier
Release Date : 2013-10-22

Microdialysis In The Neurosciences written by T.E. Robinson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.

Techniques in the Behavioral and Neural Sciences, Volume 7: Microdialysis in the Neurosciences focuses on the neurochemical methods employed in behavioral and neural sciences. The selection first elaborates on the introduction to intracerebral microdialysis, quantitative microdialysis, and microdialysis compared with other in vivo release models. Discussions focus on computational methods, post-mortem tissue analysis, perfusion methods, and features, development, and future applications of microdialysis. The text then takes a look at the practical aspects of using microdialysis for determination of brain interstitial concentrations and microdialysis and liquid chromatography. The publication examines the procedures for microdialysis with smallbore HPLC, use of microdialysis in pharmacokinetics and pharmacodynamics, and brain dialysis of monoamines. Topics include significance of monoamine concentrations in dialysates; criteria for brain dialysis of monoamines; distribution of drugs to the interstitium of various tissues; methods to measure the extracellular concentration by microdialysis; and application to studies on drug abuse. The manuscript then elaborates on the feasibility of repeated microdialysis for within-subjects design experiments and microdialysis and automated on-line analysis approach to study central cholinergic transmission in vivo. The text is a dependable reference for readers interested in the use of microdialysis in neurosciences.

Microdialysis In The Neurosciences

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Author : Terry E. Robinson
language : en
Publisher: Elsevier Science Limited
Release Date : 1991

Microdialysis In The Neurosciences written by Terry E. Robinson and has been published by Elsevier Science Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.

Until very recently most experimental studies on brain chemistry were conducted with postmortem tissue. However, because of shortcomings with postmortem methods and also the desire to directly relate neurochemistry to behavior, there has been a rapid growth of interest towards in vivo neurochemical methods. The recent availability of small diameter hollow dialysis fibres and very sensitive analytical techniques has made microdialysis practical for the routine measurement of many endogenous neurochemicals in vivo. With its adoption in the neurosciences as the preferred technique for in vivo sampling, microdialysis techniques provide the focus for this present volume. This book provides a single reference source for detailed methodological information on the conduct of microdialysis experiments for studying neurotransmitter dynamics in vivo. The emphasis is on practical considerations, and contributors have been encouraged to share their "tricks of the trade" to help other researchers quickly and easily adopt these methodologies in their own laboratories. A comprehensive overview of developments in microdialysis technology and allied analytical techniques is provided, both thought-provoking to experienced researchers, as well as a valuable aid to novices establishing these techniques for themselves.

Neuroscience Methods

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Author : Rosemary Martin
language : en
Publisher: CRC Press
Release Date : 2019-08-16

Neuroscience Methods written by Rosemary Martin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-16 with Science categories.

Unique in its coverage of such an extensive range of methods, Neuroscience Methods: A Guide for Advanced Students provides easy-to-understand descriptions of the many different techniques that are currently being used to study the brain at the molecular and cellular levels. This valuable reference text will help rescue undergraduate and postgraduate students from continuing bewilderment at the methods sections of current neuroscience publications. Topics covered include in vivo and in vitro preparations, electrophysiological, histochemical, hybridization and genetic techniques, measurement of cellular ion concentrations, methods of drug application, production of antibodies, expression systems, and neural grafting.

Modern Techniques In Neuroscience Research

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Author : Uwe Windhorst
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Modern Techniques In Neuroscience Research written by Uwe Windhorst and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

Nothing tends so much to the advancement of knowledge as the application of a new instrument. - Sir Humphry Davy, 1778-1829 Neuroscience has become a rapidly expanding endeavor that relies on a number of other sciences, such as mathematics, physics, chemistry, engineering, computer sci ence, general biology and medicine, genetics etc. In fact, many of its recent success es result from the application of ideas and methods borrowed from these fields. In sofar, it is a true interdisciplinary undertaking. This convergence of influences ac counts for part of its enormous attractiveness and fascination to students and re searchers from diverse walks of life, or science, for that matter. It is probably fair to say that a great number of neuroscience's most creative and productive proponents have been lured into this field not only by the excitement about the possibility to un mask the secrets of the human mind, but also by the appeal of a vast unknown land needing cultivation and tools to cultivate it. Danger may arise for any science if it is dominated by methods and techniques of investigation rather than by problems to be solved and concepts to be developed. This might concentrate efforts onto the technically feasible and doable, rather than On the real issues. But, On the other hand, especially the young and growing sciences are heavily dependent on the development and application of methods, often even before a problem relying on these methods may become apparent.

Microdialysis In The Neurosciences

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Author : Terry E. Robinson
language : en
Publisher: Elsevier Science Limited
Release Date : 1991-01-01

Microdialysis In The Neurosciences written by Terry E. Robinson and has been published by Elsevier Science Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-01-01 with Medical categories.

Microdialysis in the Neurosciences...

Electrochemical Methods For Neuroscience

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Author : Adrian C. Michael
language : en
Publisher: CRC Press
Release Date : 2006-12-13

Electrochemical Methods For Neuroscience written by Adrian C. Michael and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-13 with Medical categories.

Since the first implant of a carbon microelectrode in a rat 35 years ago, there have been substantial advances in the sensitivity, selectivity and temporal resolution of electrochemical techniques. Today, these methods provide neurochemical information that is not accessible by other means. The growing recognition of the versatility of electrochemi

Current Protocols In Neuroscience

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Author : Jacqueline N. Crawley
language : en
Publisher: Current Protocols
Release Date : 1997-06-01

Current Protocols In Neuroscience written by Jacqueline N. Crawley and has been published by Current Protocols this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-06-01 with Medical categories.

Current Protocols in Neuroscience (CPN) draws from techniques in molecular neurobiology, neurophysiology, neuroanatomy, neuropharmacology, and behavioral neuroscience to meet the specific needs of researchers in the full range of disciplines that is involved in studying the brain, nervous system, and corresponding behaviors. The editorial board of CPN have assembled an outstanding range of methods to enable users to explore their fields in greater depth and branch into related areas. The one-volume, looseleaf manual features carefully edited techniques with authors' troubleshooting tips and helpful comments that come from extensive experience in using these procedures. Quarterly updates, filed into the looseleaf, keep you and your laboratory current with the latest developments in this rapidly changing field. The initial purchase includes one year of updates and then subscribers may renew their annual subscriptions. Current Protocols publishes a family of laboratory manuals for bioscientists, including Molecular Biology, Immunology, Human Genetics, Protein Science, Cytometry, Cell Biology, Pharmacology, and Toxicology.

Handbook Of Neurochemistry And Molecular Neurobiology

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Author : Glen Baker
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-03-26

Handbook Of Neurochemistry And Molecular Neurobiology written by Glen Baker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-26 with Medical categories.

The Handbook is intended to be a service to the neuroscience community, to help in finding available and useful information, to point out gaps in our knowledge, and to encourage continued studies. It represents the valuable contributions of the many authors of the chapters and the guidance of the editors and most important, it represents support for research in this discipline. Based on the rapid advances in the years since the second edition

Guide To Research Techniques In Neuroscience

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Author : Matt Carter
language : en
Publisher: Academic Press
Release Date : 2022-03-26

Guide To Research Techniques In Neuroscience written by Matt Carter and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-26 with Medical categories.

Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - "Walk-through" boxes that guide readers through experiments step-by-step

Neural Plasticity And Memory

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Author : Federico Bermudez-Rattoni
language : en
Publisher: CRC Press
Release Date : 2007-04-17

Neural Plasticity And Memory written by Federico Bermudez-Rattoni and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-17 with Psychology categories.

A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq