Microfluidic Organ On A Chip Revolutionary Platforms For Disease Comprehension And Treatment
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Microfluidic Organ On A Chip Revolutionary Platforms For Disease Comprehension And Treatment
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Author : Shi-Cong Tao
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-11
Microfluidic Organ On A Chip Revolutionary Platforms For Disease Comprehension And Treatment written by Shi-Cong Tao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-11 with Science categories.
Existing culture systems have a limited ability to reproduce the complicated and dynamic microenvironment of a functioning organ. To solve the issues of conventional culture techniques, multidisciplinary researchers, involving medical doctors, stem cell and developmental biology experts, engineers and physical scientists, have emerged to innovate methods and devices. A microfluidic organ-on-a-chip (μOOC) is a cell culture device, based on microfluidic technology, which contains continuously perfused chambers with cells to simulate organ-level physiology/pathology. The μOOC is not to build a whole living organ, but rather to synthesize minimal functional units that recapitulate organ-/tissue-level functions. The μOOC can be applied to study not only the convention stimulation on cells by molecular/drugs, but also physical forces (fluid shear stress, cyclic strain and mechanical compression), organ-specific cell-cell intercommunication, and organ-organ coupling responses. There is an emerging need for innovative approaches for the production, control, analysis, and utilization of the μOOC, and even the multiple interconnected μOOC (Human-on-a-Chip). Although the μOOC has attracted much attention and is continuous being studied, there are still many difficult problems to be solved. Some of the most mentioned challenges include microenvironmental (biochemical, biophysical, biomechanical, nutrient, etc.) control, modeling tissue–tissue and multiorgan interactions, and reducing variability (automated control, high-throughput manipulation/analysis, integration of biosensing and etc.).
Highlights From Frontiers In Bioengineering And Biotechnology In 2020
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Author : Ranieri Cancedda
language : en
Publisher: Frontiers Media SA
Release Date : 2021-07-23
Highlights From Frontiers In Bioengineering And Biotechnology In 2020 written by Ranieri Cancedda and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-23 with Science categories.
Frontiers in Bioengineering and Biotechnology has evolved to become an established go-to open access publishing option for multidisciplinary bioengineering and biotechnology research and in the process has grown considerably over the last few years achieving our first Journal Impact Factor 2018 in 2019. Here we are pleased to introduce this special eBook entitled ‘Highlights from Frontiers in Bioengineering and Biotechnology in 2020’ edited by our 10 Specialty Chief Editors of Frontiers in Bioengineering and Biotechnology aiming to support Frontiers’ strong community by recognizing highly deserving authors. The work presented here highlights the broad diversity of exciting research performed across the journal and aims to put a spotlight on few areas of interest within each section. This collection showcases one or two exceptional articles published in 2020 per section of the journal. Each article has been specially handpicked by each of our 10 Specialty Chief Editors who have written a short paragraph to explain their selection and why this article is a particularly important and exciting addition to their respective fields. Our eBook thus spans Biomaterials, Biomechanics, Bionics and Biomimetics, Bioprocess Engineering, Biosafety and Biosecurity, Industrial Biotechnology, Nanobiotechnology, Preclinical Cell and Gene Therapy, Synthetic Biology and Tissue Engineering and Regenerative Medicine. All research presented here displays advances in the field of Bioengineering and Biotechnology. We hope you enjoy our selection of key articles; please ensure you are signed into your Frontiers Loop profile to download the free eBook. We also thank all authors, editors and reviewers of Frontiers in Bioengineering and Biotechnology for their contributions to our journal and look forward to another exciting year in 2021. Dr. Ranieri Cancedda (Field Chief Editor)
Molecular Diagnostics Promises And Possibilities
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Author : Mousumi Debnath
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-01-29
Molecular Diagnostics Promises And Possibilities written by Mousumi Debnath and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-29 with Medical categories.
A rapid development in diverse areas of molecular biology and genetic engineering resulted in emergence of variety of tools. These tools are not only applicable to basic researches being carried out world over, but also exploited for precise detection of abnormal conditions in plants, animals and human body. Although a basic researcher is well versed with few techniques used by him/her in the laboratory, they may not be well acquainted with methodologies, which can be used to work out some of their own research problems. The picture is more blurred when the molecular diagnostic tools are to be used by physicians, scientists and technicians working in diagnostic laboratories in hospitals, industry and academic institutions. Since many of them are not trained in basics of these methods, they come across several gray areas in understanding of these tools. The accurate application of molecular diagnostic tools demands in depth understanding of the methodology for precise detection of the abnormal condition of living body. To meet the requirements of a good book on molecular diagnostics of students, physicians, scientists working in agricultural, veterinary, medical and pharmaceutical sciences, it needs to expose the reader lucidly to: Give basic science behind commonly used tools in diagnostics Expose the readers to detailed applications of these tools and Make them aware the availability of such diagnostic tools The book will attract additional audience of pathologists, medical microbiologists, pharmaceutical sciences, agricultural scientists and veterinary doctors if the following topics are incorporated at appropriate places in Unit II or separately as a part of Unit-III in the book. Molecular diagnosis of diseases in agricultural crops Molecular diagnosis of veterinary diseases. Molecular epidemiology, which helps to differentiate various epidemic strains and sources of disease outbreaks. Even in different units of the same hospital, the infections could be by different strains of the same species and the information becomes valuable for infection control strategies. Drug resistance is a growing problem for bacterial, fungal and parasitic microbes and the molecular biology tools can help to detect the drug resistance genes without the cultivation and in vitro sensitivity testing. Molecular diagnostics offers faster help in the selection of the proper antibiotic for the treatment of tuberculosis, which is a major problem of the in the developing world. The conventional culture and drug sensitivity testing of tuberculosis bacilli is laborious and time consuming, whereas molecular diagnosis offers rapid drug resistant gene detection even from direct clinical samples. The same approach for HIV, malaria and many more diseases needs to be considered. Molecular diagnostics in the detection of diseases during foetal life is an upcoming area in the foetal medicine in case of genetic abnormalities and infectious like TORCH complex etc. The book will be equally useful to students, scientists and professionals working in the field of molecular diagnostics.
Converging Technologies For Improving Human Performance
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Author : Mihail C. Roco
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Converging Technologies For Improving Human Performance written by Mihail C. Roco and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Technology & Engineering categories.
M. C. Roco and W.S. Bainbridge In the early decades of the 21st century, concentrated efforts can unify science based on the unity of nature, thereby advancing the combination of nanotechnology, biotechnology, information technology, and new technologies based in cognitive science. With proper attention to ethical issues and societal needs, converging in human abilities, societal technologies could achieve a tremendous improvement outcomes, the nation's productivity, and the quality of life. This is a broad, cross cutting, emerging and timely opportunity of interest to individuals, society and humanity in the long term. The phrase "convergent technologies" refers to the synergistic combination of four major "NBIC" (nano-bio-info-cogno) provinces of science and technology, each of which is currently progressing at a rapid rate: (a) nanoscience and nanotechnology; (b) biotechnology and biomedicine, including genetic engineering; (c) information technology, including advanced computing and communications; (d) cognitive science, including cognitive neuroscience. Timely and Broad Opportunity. Convergence of diverse technologies is based on material unity at the nanoscale and on technology integration from that scale.
3d Printing And Biofabrication
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Author :
language : en
Publisher:
Release Date : 19??
3d Printing And Biofabrication written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 19?? with categories.
Fundamentals Of Biomems And Medical Microdevices
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Author : Steven Saliterman
language : en
Publisher: SPIE Press
Release Date : 2006
Fundamentals Of Biomems And Medical Microdevices written by Steven Saliterman and has been published by SPIE Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.
The world is on the threshold of a revolution that will change medicine and how patients are treated forever. Bringing together the creative talents of electrical, mechanical, optical and chemical engineers, materials specialists, clinical-laboratory scientists, and physicians, the science of biomedical microelectromechanical systems (bioMEMS) promises to deliver sensitive, selective, fast, low cost, less invasive, and more robust methods for diagnostics, individualized treatment, and novel drug delivery. This book is an introduction to this multidisciplinary technology and the current state of micromedical devices in use today. The first text of its kind dedicated to bioMEMS training. Fundamentals of BioMEMS and Medical Microdevices is Suitable for a single semester course for senior and graduate-level students, or as an introduction to others interested or already working in the field.
Stereolithography
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Author : Paulo Jorge Bártolo
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-03-18
Stereolithography written by Paulo Jorge Bártolo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-18 with Technology & Engineering categories.
Stereolithography: Materials, Processes and Applications will focus on recent advances in stereolithography covering aspects related to the most recent advances in the field, in terms of fabrication processes (two-photon polymerization, micro-stereolithography, infrared stereolithography and stereo-thermal-lithography), materials (novel resins, hydrogels for medical applications and highly reinforced resins with ceramics and metals), computer simulation and applications.
Bionanomaterials
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Author : Ravindra Pratap Singh
language : en
Publisher: IOP Publishing Limited
Release Date : 2021-06-28
Bionanomaterials written by Ravindra Pratap Singh and has been published by IOP Publishing Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-28 with Medical categories.
This reference text brings together comprehensive reviews of the latest research in the field of bionanomaterials, with a focus on fundamentals and biomedical applications. The major applications covered include nanobiosensing, nanomedicine, diagnostics, therapeutics, tissue engineering and green bionanotechnology.
Computer Aided Tissue Engineering
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Author : Michael A.K. Liebschner
language : en
Publisher: Humana Press
Release Date : 2012-06-14
Computer Aided Tissue Engineering written by Michael A.K. Liebschner and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-14 with Science categories.
The recent revolution in the biological sciences and bioengineering, along with the advancements of modern design and manufacturing, biomaterials, biology, and biomedicine, have brought about the new field of computer-aided tissue engineering. Advances in this fascinating new area of study encompass broad applications in large-scale tissue engineering fabrication, artificial organs, orthopaedic implants, and biological chips. Computer-Aided Tissue Engineering highlights the interdisciplinary nature of this topic and reviews the current state of computer-aided three-dimensional tissue modeling, tissue classification, and tissue fabrication and implantation. Particular focus is placed on rapid prototyping and direct digital fabrication for cell and organs, construction of tissue analogs, and precursors to 3D tissue scaffolds. Written for the highly successful Methods in Molecular BiologyTM series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Current and practical, Computer-Aided Tissue Engineering provides a coherent framework for researchers interested in these vital technologies and for clinicians who plan to implement them.
Microfluidic Technologies For Human Health
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Author : Utkan Demirci
language : en
Publisher: World Scientific
Release Date : 2012
Microfluidic Technologies For Human Health written by Utkan Demirci and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
Ch. 1. A microscale bioinspired cochlear-like sensor / Robert D. White, Robert Littrell, and Karl Grosh -- ch. 2. Systematic evaluation of the efficiencies of proteins and chemicals in pharmaceutical applications / Morgan Hamon and Jong Wook Hong -- ch. 3. Microfluidic glucose sensors / Jithesh V. Veetil [und weitere] -- ch. 4. Applications of microfabrication and microfluidic techniques in mesenchymal stem cell research / Abhijit Majumder [und weitere] -- ch. 5. Patient-specific modeling of low-density lipoprotein transport in coronary arteries / Ufuk Olgac -- ch. 6. Point-of-care microdevices for global health diagnostics of infectious diseases / Sau Yin Chin [und weitere] -- ch. 7. Integrated microfluidic sample preparation for chip-based molecular diagnostics / Jane Y. Zhang [und weitere] -- ch. 8. Microfluidic devices for cellular proteomic studies / Yihong Zhan and Chang Lu -- ch. 9. Microfluidics for neuroscience: novel tools and future implications / Vivian M. Hernandez and P. Hande Ozdinler -- ch. 10. Microfluidics: on-chip platforms as in vitro disease models / Shan Gao, Erkin Seker, and Martin L. Yarmush -- ch. 11. Application of microfluidics in stem cell and tissue engineering / Sasha H. Bakhru, Christopher Highley, and Stefan Zappe -- ch. 12. Microfluidic "on-the-fly" fabrication of microstructures for biomedical applications / Edward Kang, Sau Fung Wong, and Sang-Hoon Lee -- ch. 13. Microfluidics as a promising tool toward distributed viral detection / Elodie Sollier and Dino Di Carlo -- ch. 14. Electrophoresis and dielectrophoresis for lab-on-a-chip (LOC) analyses / Yagmur Demircan, Gurkan Yilmaz, and Haluk Kulah -- ch. 15. Ultrasonic embossing of carbon nanotubes for the fabrication of polymer microfluidic chips for DNA sample purification / Puttachat Khuntontong, Min Gong, and Zhiping Wang -- ch. 16. Ferrofluidics / A. Rezzan Kose and Hur Koser -- ch. 17. Antibody-based blood bioparticle capture and separation using microfluidics for global health / ZhengYuan Luo [und weitere] -- ch. 18. Applications of quantum dots for fluorescence imaging in biomedical research / ShuQi Wang [und weitere]