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Microfluidics And Biosensors In Cancer Research


Microfluidics And Biosensors In Cancer Research
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Microfluidics And Biosensors In Cancer Research


Microfluidics And Biosensors In Cancer Research
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Author : David Caballero
language : en
Publisher: Springer Nature
Release Date : 2022-06-27

Microfluidics And Biosensors In Cancer Research written by David Caballero and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-27 with Medical categories.


This book offers a comprehensive overview of the development and application of microfluidics and biosensors in cancer research, in particular, their applications in cancer modeling and theranostics. Over the last decades, considerable effort has been made to develop new technologies to improve the diagnosis and treatment of cancer. Microfluidics has proven to be a powerful tool for manipulating biological fluids with high precision and efficiency and has already been adopted by the pharmaceutical and biotechnology industries. With recent technological advances, particularly biosensors, microfluidic devices have increased their usefulness and importance in oncology and cancer research. The aim of this book is to bring together in a single volume all the knowledge and expertise required for the development and application of microfluidic systems and biosensors in cancer modeling and theranostics. It begins with a detailed introduction to the fundamental aspects of tumor biology, cancer biomarkers, biosensors and microfluidics. With this knowledge in mind, the following sections highlight important advances in developing and applying biosensors and microfluidic devices in cancer research at universities and in the industry. Strategies for identifying and evaluating potent disease biomarkers and developing biosensors and microfluidic devices for their detection are discussed in detail. Finally, the transfer of these technologies into the clinical environment for the diagnosis and treatment of cancer patients will be highlighted. By combining the recent advances made in the development and application of microfluidics and biosensors in cancer research in academia and clinics, this book will be useful literature for readers from a variety of backgrounds. It offers new visions of how this technology can influence daily life in hospitals and companies, improving research methodologies and the prognosis of cancer patients.



Biosensor Based Advanced Cancer Diagnostics


Biosensor Based Advanced Cancer Diagnostics
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Author : Raju Khan
language : en
Publisher: Elsevier
Release Date : 2021-08-27

Biosensor Based Advanced Cancer Diagnostics written by Raju Khan and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-27 with Medical categories.


Early diagnosis of cancer and other non-oncological disorders gives a significant advantage for curing the disease and improving patient's life expectancy. Recent advances in biosensor-based techniques which are designed for specific biomarkers can be exploited for early diagnosis of diseases. Biosensor Based Advanced Cancer Diagnostics covers all available biosensor-based approaches and comprehensive technologies; along with their application in diagnosis, prognosis and therapeutic management of various oncological disorders. Besides this, current challenges and future aspects of these diagnostic approaches have also been discussed. This book offers a view of recent advances and is also helpful for designing new biosensor-based technologies in the field of medical science, engineering and biomedical technology. Biosensor Based Advanced Cancer Diagnostics helps biomedical engineers, researchers, molecular biologists, oncologists and clinicians with the development of point of care devices for disease diagnostics and prognostics. It also provides information on developing user friendly, sensitive, stable, accurate, low cost and minimally invasive modalities which can be adopted from lab to clinics. This book covers in-depth knowledge of disease biomarkers that can be exploited for designing and development of a range of biosensors. The editors have summarized the potential cancer biomarkers and methodology for their detection, plus transferring the developed system to clinical application by miniaturization and required integration with microfluidic systems. Covers design and development of advanced platforms for rapid diagnosis of cancerous biomarkers Takes a multidisciplinary approach to sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical systems, and device packaging for point-of-care applications Offers an insight into how to develop cost-effective diagnostics for early detection of cancer



Electrochemical Biosensors


Electrochemical Biosensors
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Author : Serge Cosnier
language : en
Publisher: CRC Press
Release Date : 2015-01-26

Electrochemical Biosensors written by Serge Cosnier and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-26 with Science categories.


Since four decades, rapid detection and monitoring in clinical and food diagnostics and in environmental and biodefense have paved the way for the elaboration of electrochemical biosensors. Thanks to their adaptability, ease of use in relatively complex samples, and their portability, electrochemical biosensors now are one of the mainstays of analy



Chemical Carcinogenesis


Chemical Carcinogenesis
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Author : Trevor M. Penning
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-03-03

Chemical Carcinogenesis written by Trevor M. Penning and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-03 with Medical categories.


This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many cancers. The multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action will be a focal point. The balance between metabolic activation to form biological reactive intermediates and their detoxification, ensuing DNA-lesions and their repair will be profiled. It will describe the chemical changes that occur in DNA that result from endogenous insults including epigenetic changes that lead to gene silencing. It will describe major mechanisms of mutagenesis, affects on tumor suppressor genes and proto-oncogenes, and how cell-cycle check points can be by-passed by the "stealth-like" properties of chemical carcinogens. Environmental agents that can promote tumor formation will be discussed. The monograph will have wide appeal as a knowledge base for graduate students, post-doctoral fellows and faculty interested in this aspect of cancer causation and research.



Biosensors And Molecular Technologies For Cancer Diagnostics


Biosensors And Molecular Technologies For Cancer Diagnostics
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Author : Keith E. Herold
language : en
Publisher: Taylor & Francis
Release Date : 2012-05-29

Biosensors And Molecular Technologies For Cancer Diagnostics written by Keith E. Herold and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-29 with Medical categories.


Bridging the gap between research and clinical application, Biosensors and Molecular Technologies for Cancer Diagnostics explores the use of biosensors as effective alternatives to the current standard methods in cancer diagnosis and detection. It describes the major aspects involved in detecting and diagnosing cancer as well as the basic elements



Microfluidic Biosensors


Microfluidic Biosensors
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Author : Wing Cheung Mak
language : en
Publisher: Elsevier
Release Date : 2022-11-05

Microfluidic Biosensors written by Wing Cheung Mak and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-05 with Technology & Engineering categories.


Microfluidic Biosensors provides a comprehensive overview covering the most recent emerging technologies on the design, fabrication, and integration of microfluidics with transducers. These form various integrated microfluidic biosensors with device configurations ranging from 2D to 4D levels. Coverage also includes advanced printed microfluidic biosensors, flexible microfluidics for wearable biosensors, autonomous lab-on-a-chip biosensors, CMOS-base microanalysis systems, and microfluidic devices for mobile phone biosensing. The editors and contributors of this book represent both academia and industry, come from a varied range of backgrounds, and offer a global perspective. This book discusses the design and principle of microfluidic systems and uses them for biosensing applications. The microfluidic fabrication technologies covered in this book provide an up-to-date view, allowing the community to think of new ways to overcome challenges faced in this field. The focus is on existing and emerging technologies not currently being analyzed extensively elsewhere, providing a unique perspective and much-needed content. The editors have crafted this book to be accessible to all levels of academics from graduate students, researchers, and professors working in the fields of biosensors, microfluidics design, material science, analytical chemistry, biomedical devices, and biomedical engineering. It can also be useful for industry professionals working for microfluidic device manufacturers, or in the industry of biosensors and biomedical devices. - Presents an in-depth overview of microfluidic biosensors and associated emerging technologies such as printed microfluidics and novel transducers - Addresses a range of microfluidic biosensors with device configurations ranging from 2D to 4D levels - Includes the commercialization aspects of microfluidic biosensors that provide insights for scientists and engineers in research and development



2021 Ieee 34th International Conference On Micro Electro Mechanical Systems Mems


2021 Ieee 34th International Conference On Micro Electro Mechanical Systems Mems
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Author :
language : en
Publisher:
Release Date : 2021

2021 Ieee 34th International Conference On Micro Electro Mechanical Systems Mems written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.




Metal Oxides For Biomedical And Biosensor Applications


Metal Oxides For Biomedical And Biosensor Applications
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Author : Kunal Mondal
language : en
Publisher: Elsevier
Release Date : 2021-12-04

Metal Oxides For Biomedical And Biosensor Applications written by Kunal Mondal and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-04 with Technology & Engineering categories.


Metal Oxides for Biomedical and Biosensor Applications gives an in-depth overview of the emerging research in the biomedical and biosensing applications of metal oxides, including optimization of their surface and bulk properties. Sections cover biomedical applications of metal oxides for use in cell cultures, antibacterial and antimicrobial treatments, dental applications, drug delivery, cancer therapy, immunotherapy, photothermal therapy, tissue engineering, and metal oxide-based biosensor development. As advanced and biofunctionalized nano/micro structured metal oxides are finding applications in microfluidics, optical sensors, electrochemical sensors, DNA-based biosensing, imaging, diagnosis and analysis, this book provides a comprehensive update on the topic. Additional sections cover research challenges, technology limitations, and future trends in metal oxides and their composites regarding their usage in biomedical applications. - Includes an overview of the important applications of metal oxides for biomedical and biosensing technologies - Addresses the relationship between material properties, such as structure, morphology, composition and performance - Reviews the design and fabrication strategies of metal oxides for use in medical and biosensing applications



Aptamers Engineered Nanocarriers For Cancer Therapy


Aptamers Engineered Nanocarriers For Cancer Therapy
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Author : Prashant Kesharwani
language : en
Publisher: Woodhead Publishing
Release Date : 2022-09-25

Aptamers Engineered Nanocarriers For Cancer Therapy written by Prashant Kesharwani and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-25 with Technology & Engineering categories.


Aptamers Engineered Nanocarriers for Cancer Therapy details the selection technologies, biological characteristics, and clinical uses of aptamer-based nano agents for cancer therapeutics. The book helps facilitate speedy solutions for some of the problems pertaining to the manufacture of nano-aptamers – such as toxicity, thermal stability, cost efficiency, tumor penetration and blood stability. Key chapters cover cell-SELEX technology for aptamer selection, mechanisms of multi-drug resistance of cancer, the relevance of aptamers as anticancer therapies, as well as the broad range of aptamer-functionalized nanostructures available. This book provides exciting insights into this relatively new approach to cancer therapeutics, and will be of interest to materials scientists, biomedical engineers, molecular biologists, biochemists and clinical scientists, with a focus on cancer therapy. - Reviews the mechanisms behind multi-drug resistance (MDR) in cancer and how aptamer-mediated novel therapeutic agents and strategies can facilitate MDR reversal - Covers a range of aptamers engineered nanostructures, including PLGA nanoparticles, silica nanoparticles, quantum dots, nucleic acid aptamers, and more - Discusses the challenges associated with using aptamers as cancer therapeutics and how this translates into clinical use



Biomedical Applications Of Microfluidic Devices


Biomedical Applications Of Microfluidic Devices
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Author : Michael R. Hamblin
language : en
Publisher: Academic Press
Release Date : 2020-11-12

Biomedical Applications Of Microfluidic Devices written by Michael R. Hamblin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-12 with Technology & Engineering categories.


Biomedical Applications of Microfluidic Devices introduces the subject of microfluidics and covers the basic principles of design and synthesis of actual microchannels. The book then explores how the devices are coupled to signal read-outs and calibrated, including applications of microfluidics in areas such as tissue engineering, organ-on-a-chip devices, pathogen identification, and drug/gene delivery. This book covers high-impact fields (microarrays, organ-on-a-chip, pathogen detection, cancer research, drug delivery systems, gene delivery, and tissue engineering) and shows how microfluidics is playing a key role in these areas, which are big drivers in biomedical engineering research. This book addresses the fundamental concepts and fabrication methods of microfluidic systems for those who want to start working in the area or who want to learn about the latest advances being made. The subjects covered are also an asset to companies working in this field that need to understand the current state-of-the-art. The book is ideal for courses on microfluidics, biosensors, drug targeting, and BioMEMs, and as a reference for PhD students. The book covers the emerging and most promising areas of biomedical applications of microfluidic devices in a single place and offers a vision of the future. - Covers basic principles and design of microfluidics devices - Explores biomedical applications to areas such as tissue engineering, organ-on-a-chip, pathogen identification, and drug and gene delivery - Includes chemical applications in organic and inorganic chemistry - Serves as an ideal text for courses on microfluidics, biosensors, drug targeting, and BioMEMs, as well as a reference for PhD students