Microrna Medical Evidence
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Microrna Medical Evidence
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Author : Gaetano Santulli
language : en
Publisher: Springer
Release Date : 2015-12-11
Microrna Medical Evidence written by Gaetano Santulli and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-11 with Science categories.
This volume explores microRNA function in a wide array of human disorders, providing a clinical basis for precision medicine and personalized therapies using these molecules. The twenty-one chapters, all authored by internationally-renowned experts, open with an introduction contextualizing microRNA manipulation within today’s initiatives towards precision medicine. The following chapters explore the clinical role of microRNAs in the diagnosis and treatment of metabolic and cardiovascular disorders, focusing on mitochondrial fitness, arterial hypertension, cardiovascular remodeling, cerebrovascular disease, pulmonary hypertension, diabetic kidney disease, and kidney transplantation. The subsequent chapters discuss the importance of microRNAs in the wound healing process and in skin disease, in the pathogenesis of allergy, in human ovulation, and in infection. The book concludes with chapters which outline the emerging role of microRNAS in doping and detail microRNA profiling. microRNA: Medical Evidence is an ideal companion to both microRNA: Basic Scienceand microRNA: Cancer. Taken together, these three books provide a state-of-the-art overview of this rapidly-expanding and fascinating field, from the molecular level to clinical practice. It will be invaluable to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA in basic science, cancer and clinical practice.
Microrna Medical Evidence
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Author : Gaetano Santulli
language : en
Publisher:
Release Date : 2015
Microrna Medical Evidence written by Gaetano Santulli and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
This volume explores microRNA function in a wide array of human disorders, providing a clinical basis for precision medicine and personalized therapies using these molecules. The twenty-one chapters, all authored by internationally-renowned experts, open with an introduction contextualizing microRNA manipulation within today's initiatives towards precision medicine. The following chapters explore the clinical role of microRNAs in the diagnosis and treatment of metabolic and cardiovascular disorders, focusing on mitochondrial fitness, arterial hypertension, cardiovascular remodeling, cerebrovascular disease, pulmonary hypertension, diabetic kidney disease, and kidney transplantation. The subsequent chapters discuss the importance of microRNAs in the wound healing process and in skin disease, in the pathogenesis of allergy, in human ovulation, and in infection. The book concludes with chapters which outline the emerging role of microRNAS in doping and detail microRNA profiling. microRNA: Medical Evidence is an ideal companion to both microRNA: Basic Science and microRNA: Cancer. Taken together, these three books provide a state-of-the-art overview of this rapidly-expanding and fascinating field, from the molecular level to clinical practice. It will be invaluable to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA in basic science, cancer and clinical practice.
Microrna Basic Science
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Author : Gaetano Santulli
language : en
Publisher:
Release Date : 2015
Microrna Basic Science written by Gaetano Santulli and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
This volume explores microRNA pathophysiology, focusing on basic concepts in molecular and cellular biology. Chapters contributed by leading scientists examine recently discovered pathways in several processes, including aging, diabetes, cardiovascular disease, hematopoiesis, and mitochondrial fitness. The authors contextualize microRNAs within epigenetics and micropeptidomics, angiongenesis and atherosclerosis, endometrial pathophysiology, and more. Throughout, numerous color photographs, diagrams of molecular pathways, and tables enhance the text. microRNA: Basic Science is an ideal companion to both microRNA: Medical Evidence and microRNA: Cancer. Taken together, these three books provide a state-of-the-art overview of this rapidly-expanding and fascinating field, from the molecular level to clinical practice. It will be invaluable to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA in basic science, cancer and clinical practice.
Microrna Basic Science
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Author : Gaetano Santulli
language : en
Publisher: Springer
Release Date : 2015-12-11
Microrna Basic Science written by Gaetano Santulli and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-11 with Science categories.
This volume explores microRNA pathophysiology, focusing on basic concepts in molecular and cellular biology. Chapters contributed by leading scientists examine recently discovered pathways in several processes, including aging, diabetes, cardiovascular disease, hematopoiesis, and mitochondrial fitness. The authors contextualize microRNAs within epigenetics and micropeptidomics, angiongenesis and atherosclerosis, endometrial pathophysiology, and more. Throughout, numerous color photographs, diagrams of molecular pathways, and tables enhance the text. microRNA: Basic Science is an ideal companion to both microRNA: Medical Evidenceand microRNA: Cancer. Taken together, these three books provide a state-of-the-art overview of this rapidly-expanding and fascinating field, from the molecular level to clinical practice. It will be invaluable to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA in basic science, cancer and clinical practice.
Microrna Cancer
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Author : Gaetano Santulli
language : en
Publisher:
Release Date : 2015
Microrna Cancer written by Gaetano Santulli and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
This volume thoroughly explores of the functional role of microRNAs in cancer. It not only expertly describes the molecular mechanisms underlying the malignant transformation process but also compiles cutting-edge research on microRNAs in several forms of cancer, including colorectal cancer, pancreatic cancer, leukemia/lymphoma, prostate cancer, lung cancer, ovarian cancer, and bone cancer. Distinguished experts, currently working in prestigious institutions, elegantly discuss these fundamental themes. The text, which opens with a foreword by the renowned Dr. Carlo M. Croce, is enhanced by abundant color photographs, schemes, diagrams, and tables that fully support and complement the content. microRNA: Cancer is an ideal companion to both microRNA: Basic Science and microRNA: Medical Evidence. Taken together, these three books provide a state-of-the-art overview of this rapidly-expanding and fascinating field, from the molecular level to clinical practice. It will be invaluable to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA in basic science, cancer and clinical practice.
Microrna Cancer
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Author : Gaetano Santulli
language : en
Publisher: Springer
Release Date : 2015-12-11
Microrna Cancer written by Gaetano Santulli and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-11 with Science categories.
This volume thoroughly explores of the functional role of microRNAs in cancer. It not only expertly describes the molecular mechanisms underlying the malignant transformation process but also compiles cutting-edge research on microRNAs in several forms of cancer, including colorectal cancer, pancreatic cancer, leukemia/lymphoma, prostate cancer, lung cancer, ovarian cancer, and bone cancer. Distinguished experts, currently working in prestigious institutions, elegantly discuss these fundamental themes. The text, which opens with a foreword by the renowned Dr. Carlo M. Croce, is enhanced by abundant color photographs, schemes, diagrams, and tables that fully support and complement the content. microRNA: Cancer is an ideal companion to both microRNA: Basic Science andmicroRNA: Medical Evidence. Taken together, these three books provide a state-of-the-art overview of this rapidly-expanding and fascinating field, from the molecular level to clinical practice. It will be invaluable to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA in basic science, cancer and clinical practice.
Microrna In Development And In The Progression Of Cancer
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Author : Shree Ram Singh
language : en
Publisher: Springer Science & Business
Release Date : 2014-04-21
Microrna In Development And In The Progression Of Cancer written by Shree Ram Singh and has been published by Springer Science & Business this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-21 with Medical categories.
miRNAs are a class of endogenous, small non-protein coding RNA molecules (~ 22 nucleotides) which are novel post-transcriptional regulators of gene expression. Since we have hundreds of miRNAs, the major challenge is now to understand their specific biological function. In fact the experimental evidence suggests that signaling pathways could be ideal candidates for miRNA-mediated regulation. Several studies suggest that miRNAs affect the responsiveness of cells to signaling molecules such as WNT, Notch, TGF-β and EGFR. Altered expression of particular miRNAs has been implicated in the onset and development of cancer and could be used as potential biomarkers for the disease. Recently, many studies have found miRNAs have crucial regulatory roles in Cancer stem cells (CSCs) a kind of tumor initiating cells (TICs) and dormancy. Findings also suggest that DNA methylation may be important in regulating the expression of many miRNAs in several cancer initiating cells. Several miRNAs are known to either upregulated or downregulated in CSCs when compared to non-cancerous cells from the same tissues. CSCs are a small subpopulation of cells identified in a variety of tumors and involve in self-renewal, differentiation, chemoresistance and tumorigenesis. The volume will give a comprehensive account of important advancements in the area of miRNAs and cancer.
Microrna Profiling
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Author : Sweta Rani
language : en
Publisher: Springer Nature
Release Date : 2022-11-28
Microrna Profiling written by Sweta Rani and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-28 with Science categories.
This second edition provides updated and comprehensive methods on miRNA biogenesis and their role in the development and progression of various human diseases. Chapters detail miRNA biogenesis, isolating RNA, extracellular vesicles (EVs), circulating miRNAs, analyzing miRNA and miRDeep-P2, protocols for total RNA isolation from cells, cell-derived products, isolation and characterization of exosomes, serum, plasma specimens, and software tools. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, MicroRNA Profiling: Methods and Protocols, Second Edition aims to provide comprehensive and accessible methods to undergraduate, graduate, and established scientist.
Micrornas In Medicine
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Author : Charles H. Lawrie
language : en
Publisher: Wiley-Blackwell
Release Date : 2013-12-20
Micrornas In Medicine written by Charles H. Lawrie and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-20 with Science categories.
MicroRNAs in Medicine provides an access point into the current literature on microRNA for both scientists and clinicians, with an up-to-date look at what is happening in the emerging field of microRNAs and their relevance to medicine. Each chapter is a comprehensive review, with descriptions of the latest microRNA research written by international leaders in their field. Opening with an introduction to what microRNAs are and how they function, the book goes on to explore the role of microRNAs in normal physiological functions, infectious diseases, non-infectious diseases, cancer, circulating microRNAs as non-invasive biomarkers, and finally their potential as novel therapeutics. Including background information on the field as well as reviews of the latest research breakthroughs, MicroRNAs in Medicine is a one-stop source of information to satisfy the specialists and non-specialists alike, appealing to students, researchers, and clinicians interested in understanding the potential of microRNAs in medicine and research.
Circulating Micrornas In Disease Diagnostics And Their Potential Biological Relevance
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Author : Peter Igaz
language : en
Publisher: Springer
Release Date : 2015-11-25
Circulating Micrornas In Disease Diagnostics And Their Potential Biological Relevance written by Peter Igaz and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-25 with Medical categories.
MicroRNAs as the endogenous mediators of RNA interference have experienced an unprecedented career in recent years, highlighting their pathogenic, diagnostic and potential therapeutic relevance. Beside tissue microRNAs, they are also found in body fluids, most notably in blood. Significant differences of circulating microRNA levels have been found in various diseases, making them candidates for minimally invasive markers of disease, for example tumor malignancy. The book focuses on the potential diagnostic applicability of circulating microRNAs in various diseases and their potential biological significance.