Mitochondrial Physiology And Pathology
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Mitochondrial Physiology And Pathology
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Author : Gary Fiskum
language : en
Publisher: Van Nostrand Reinhold Company
Release Date : 1986
Mitochondrial Physiology And Pathology written by Gary Fiskum and has been published by Van Nostrand Reinhold Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Medical categories.
Mitochondria
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Author : Francesco Bruni
language : en
Publisher: Mdpi AG
Release Date : 2021-11-09
Mitochondria written by Francesco Bruni and has been published by Mdpi AG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-09 with Science categories.
Mitochondria play an increasingly central role in the context of cellular physiology. These organelles possess their own genome (mtDNA), which is functionally coordinated with the nuclear genome. Mitochondrial gene expression is mediated by molecular processes (replication, transcription, translation, and assembly of respiratory chain complexes) that all take place within the mitochondria. Several aspects of mtDNA expression have already been well characterized, but many more either are under debate or have yet to be discovered. Understanding the molecular processes occurring in mitochondria also has clinical relevance. Dysfunctions affecting these important metabolic 'hubs' are associated with a whole range of severe disorders, known as mitochondrial diseases. In recent years, significant progress has been made to understand the pathogenic mechanisms underlying mitochondrial dysfunction; however, to date, mitochondrial diseases are complex genetic disorders without any effective therapy. Current therapeutic strategies and clinical trials are aimed at mitigating clinical manifestations and slowing the disease progression to improve the quality of life of patients. The goal of the Special Issue 'Mitochondria: from Physiology to Pathology' published in Life (ISSN: 2075-1729) was to collect research and review articles covering the physiological and pathological aspects related to mtDNA maintenance and gene expression, mitochondrial biogenesis, protein import, organelle metabolism, and quality control.
Mitochondrial Physiology And Pathology
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Author :
language : en
Publisher:
Release Date : 2009
Mitochondrial Physiology And Pathology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Mitochondria From Physiology To Pathology
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Author : Francesco Bruni
language : en
Publisher:
Release Date : 2021
Mitochondria From Physiology To Pathology written by Francesco Bruni and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
Mitochondria play an increasingly central role in the context of cellular physiology. These organelles possess their own genome (mtDNA), which is functionally coordinated with the nuclear genome. Mitochondrial gene expression is mediated by molecular processes (replication, transcription, translation, and assembly of respiratory chain complexes) that all take place within the mitochondria. Several aspects of mtDNA expression have already been well characterized, but many more either are under debate or have yet to be discovered. Understanding the molecular processes occurring in mitochondria also has clinical relevance. Dysfunctions affecting these important metabolic 'hubs' are associated with a whole range of severe disorders, known as mitochondrial diseases. In recent years, significant progress has been made to understand the pathogenic mechanisms underlying mitochondrial dysfunction; however, to date, mitochondrial diseases are complex genetic disorders without any effective therapy. Current therapeutic strategies and clinical trials are aimed at mitigating clinical manifestations and slowing the disease progression to improve the quality of life of patients. The goal of the Special Issue 'Mitochondria: from Physiology to Pathology' published in Life (ISSN: 2075-1729) was to collect research and review articles covering the physiological and pathological aspects related to mtDNA maintenance and gene expression, mitochondrial biogenesis, protein import, organelle metabolism, and quality control.
Role Of Mitochondrial Quality Control In Myocardial And Microvascular Physiology And Pathophysiology
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Author : Hao Zhou
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-01
Role Of Mitochondrial Quality Control In Myocardial And Microvascular Physiology And Pathophysiology written by Hao Zhou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-01 with Science categories.
The heart is a strong muscular pump that enables tissue and organ perfusion. Therefore, a continuous supply of fresh blood is vital for cardiac function. In coronary artery disease, plaques or thrombi induce rapid occlusion, which restricts blood flow to the heart. The primary effect of coronary artery disease is substantial cardiomyocyte death, which prevents the heart from effectively pumping blood to vital organs.
Mitochondrial Physiology And Pathology Concepts Of Programmed Death Of Organlles Cells And Organisms
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Author : Vladimir P. Skulachev
language : en
Publisher:
Release Date : 1999
Mitochondrial Physiology And Pathology Concepts Of Programmed Death Of Organlles Cells And Organisms written by Vladimir P. Skulachev and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.
Mitochondrial Dna And The Immuno Inflammatory Response New Frontiers To Control Specific Microbial Diseases
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Author : Dilvani Oliveira Santos
language : en
Publisher: Bentham Science Publishers
Release Date : 2022-08-02
Mitochondrial Dna And The Immuno Inflammatory Response New Frontiers To Control Specific Microbial Diseases written by Dilvani Oliveira Santos and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-02 with Medical categories.
Mitochondria are multifunctional organelles that actively participate in the immune-inflammatory response in various pathologies. This volume updates readers on knowledge about mitochondria function. The editors have compiled six chapters about inflammation in its broadest sense, with contributions from active groups of cell biologists, infectologists and pathologists. The chapters in this volume focus on research related to five notable diseases: (1) two diseases (one bacterial and one viral) in which the exacerbation of the inflammatory response can lead to neuropathies: leprosy (one of the oldest diseases in the world) and Zika fever (a disease relatively new in Brazil) (2) three diseases (two bacterial and one viral) in which the exacerbation of the inflammatory response can lead to irreversible lung damage that can cause rapid death: tuberculosis, pneumonia and the most recent global disease, COVID- 19. New information about mitochondrial biology is presented, such as the effect of aerobic physical exercise as a stimulator for mitochondria multiplication, and the role of mitochondrial damage in inducing immune-inflammatory responses to pathogens. The contents shed light on mitochondrial biochemical pathways that could serve as potential therapeutic targets. This is an important reference for scholars (cell biologists, microbiologists) in universities, hospitals and scientific research centers working on biological and biomedical problems, and for health professionals involved in infection control.
Studies On The Physiology And Pathology Of The Blood
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Author : Proctor Fund for the Study of Chronic Disease
language : en
Publisher:
Release Date : 1922
Studies On The Physiology And Pathology Of The Blood written by Proctor Fund for the Study of Chronic Disease and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1922 with Blood categories.
Pathobiology Of Human Disease
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Author :
language : en
Publisher: Elsevier
Release Date : 2014-08-01
Pathobiology Of Human Disease written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-01 with Science categories.
Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human - Organ Systems - Molecular Pathology/Basic Mechanisms of Diseases - Animal Models/Other Model Systems - Experimental Pathology - Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. - Reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting - Articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of "Normal" and "Disease" anatomy and histology images - Fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions
Cerebrovascular Bibliography
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Author :
language : en
Publisher:
Release Date : 1969
Cerebrovascular Bibliography written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1969 with categories.