Mitotic And Meiotic Analysis Of The Centromere From Chromosome Iii Of The Yeast Saccharomyces Cerevisiae
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Mitotic And Meiotic Analysis Of The Centromere From Chromosome Iii Of The Yeast Saccharomyces Cerevisiae
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Author : Arlene M. Gaudet
language : en
Publisher:
Release Date : 1989
Mitotic And Meiotic Analysis Of The Centromere From Chromosome Iii Of The Yeast Saccharomyces Cerevisiae written by Arlene M. Gaudet and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Cell division categories.
The Centromere
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Author : K. H. Andy Choo
language : en
Publisher: Oxford University Press, USA
Release Date : 1997
The Centromere written by K. H. Andy Choo and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.
The centromere is an essential structure on all eukaryotic chromosomes that allows the equipartition of chromosomes during mitotic and meiotic cell divisions. Since its cytogenetic recognition as a constructed part of a chromosome many decades ago, great advances have been made in ourunderstanding of this intriguing structure, especially at the molecular level. This book brings together all available information on the centromere. It covers in details the DNA and protein components of this structure, and their individual functions, in species as diverse as budding and fissionyeasts, nematodes, Drosophila, mice, and humans; newly discovered roles of the centromere in marshalling "passenger" proteins; important emerging concepts such as latent centromeres and epigenetic factors; cytogenetic problems associated with centromere abnormalities; and practical application ofcentromere studies, such as in the construction of human artificial chromosomes for gene therapy. Supported by ample illustrations, the book is written with sufficient simplicity and detail to suit both specialist and non-specialist scholars. It is the first book on the subject
Centromere
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Author : Durdica Ugarkovic
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-06-12
Centromere written by Durdica Ugarkovic and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-12 with Science categories.
The centromere is a chromosomal region that enables the accurate segregation of chromosomes during mitosis and meiosis. It holds sister chromatids together, and through its centromere DNA–protein complex known as the kinetochore binds spindle microtubules to bring about accurate chromosome movements. Despite this conserved function, centromeres exhibit dramatic difference in structure, size, and complexity. Extensive studies on centromeric DNA revealed its rapid evolution resulting often in significant difference even among closely related species. Such a plasticity of centromeric DNA could be explained by epigenetic c- trol of centromere function, which does not depend absolutely on primary DNA sequence. According to epigenetic centromere concept, which is thoroughly d- cussed by Tanya Panchenko and Ben Black in Chap. 1 of this book, centromere activation or inactivation might be caused by modifications of chromatin. Such acquired chromatin epigenetic modifications are then inherited from one cell di- sion to the next. Concerning centromere-specific chromatin modification, it is now evident that all centromeres contain a centromere specific histone H3 variant, CenH3, which replaces histone H3 in centromeric nucleosomes and provides a structural basis that epigenetically defines centromere and differentiates it from the surrounding chromatin. Recent insights into the CenH3 presented in this chapter add important mechanistic understanding of how centromere identity is initially established and subsequently maintained in every cell cycle.
Studies On Chromosome Iii Of Saccharomyces Cerevisiae
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Author : Kathryne Mason Mooney
language : en
Publisher:
Release Date : 1978
Studies On Chromosome Iii Of Saccharomyces Cerevisiae written by Kathryne Mason Mooney and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Chromosomes categories.
Construction And Analysis Of Modified Chromosomes In Saccharomyces Cerevisiae
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Author : Richard Tobin Surosky
language : en
Publisher:
Release Date : 1985
Construction And Analysis Of Modified Chromosomes In Saccharomyces Cerevisiae written by Richard Tobin Surosky and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Chromosomes categories.
Centromeres And Kinetochores
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Author : Ben E. Black
language : en
Publisher: Springer
Release Date : 2017-08-23
Centromeres And Kinetochores written by Ben E. Black and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-23 with Science categories.
This book presents the latest advances concerning the regulation of chromosome segregation during cell division by means of centromeres and kinetochores. The authors cover both state-of-the-art techniques and a range of species and model systems, shedding new light on the molecular mechanisms controlling the transmission of genetic material between cell divisions and from parent to offspring. The chapters cover five major areas related to the current study of centromeres and kinetochores: 1) their genetic and epigenetic features, 2) key breakthroughs at the molecular, proteomic, imaging and biochemical level, 3) the constitutive centromere proteins, 4) the role of centromere proteins in the physical process of chromosome segregation and its careful orchestration through elaborate regulation, and 5) intersections with reproductive biology, human health and disease, as well as chromosome evolution. The book offers an informative and provocative guide for newcomers as well as those already acquainted with the field.
The Kinetochore
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Author : Peter De Wulf
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-16
The Kinetochore written by Peter De Wulf and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-16 with Medical categories.
Kinetochores orchestrate the faithful transmission of chromosomes from one generation to the next. Kinetochores were first depicted over 100 years ago, but kinetochore research has progressed by leaps and bounds since the first description of their constituent DNA and proteins in the 1980s. “The Kinetochore: from Molecular Discoveries to Cancer Therapy” presents a thorough up-to-date analysis of kinetochore and centromere composition, formation, regulation, and activity, both in mitosis and meiosis, in humans and “model” eukaryotic species, and at natural and mutant neocentromeres. Recently initiated translational research on kinetochores is also discussed as kinetochores are being mined as a very rich target for the next generations of anti-cancer drugs.
The Major Transitions In Evolution
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Author : John Maynard Smith
language : en
Publisher: Oxford University Press
Release Date : 1997-10-30
The Major Transitions In Evolution written by John Maynard Smith and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-10-30 with Nature categories.
During evolution there have been several major changes in the way genetic information is organized and transmitted from one generation to the next. These transitions include the origin of life itself, the first eukaryotic cells, reproduction by sexual means, the appearance of multicellular plants and animals, the emergence of cooperation and of animal societies. This is the first book to discuss all these major transitions and their implications for our understanding of evolution.Clearly written and illustrated with many original diagrams, this book will be welcomed by students and researchers in the fields of evolutionary biology, ecology, and genetics.
Mitotic Chromosome And Spindle Dynamics In Saccharomyces Cerevisiae
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Author : Aaron French Straight
language : en
Publisher:
Release Date : 1998
Mitotic Chromosome And Spindle Dynamics In Saccharomyces Cerevisiae written by Aaron French Straight and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Chromosomes categories.
The Molecular Biology Of The Yeast Saccharomyces Life Cycle And Inheritance
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Author : Jeffrey N. Strathern
language : en
Publisher:
Release Date : 1981
The Molecular Biology Of The Yeast Saccharomyces Life Cycle And Inheritance written by Jeffrey N. Strathern and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Science categories.