Moda 11 Advances In Model Oriented Design And Analysis
DOWNLOAD
Download Moda 11 Advances In Model Oriented Design And Analysis PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Moda 11 Advances In Model Oriented Design And Analysis book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Moda 11 Advances In Model Oriented Design And Analysis
DOWNLOAD
Author : Joachim Kunert
language : en
Publisher: Springer
Release Date : 2016-06-06
Moda 11 Advances In Model Oriented Design And Analysis written by Joachim Kunert and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-06 with Mathematics categories.
This volume contains pioneering contributions to both the theory and practice of optimal experimental design. Topics include the optimality of designs in linear and nonlinear models, as well as designs for correlated observations and for sequential experimentation. There is an emphasis on applications to medicine, in particular, to the design of clinical trials. Scientists from Europe, the US, Asia, Australia and Africa contributed to this volume of papers from the 11th Workshop on Model Oriented Design and Analysis.
Moda 9 Advances In Model Oriented Design And Analysis
DOWNLOAD
Author : Alessandra Giovagnoli
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-06-10
Moda 9 Advances In Model Oriented Design And Analysis written by Alessandra Giovagnoli and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-10 with Mathematics categories.
Statisticians and experimentalists will find the latest trends in optimal experimental design research. Some papers are pioneering contributions, leading to new open research problems. It is a colection of peer reviewed papers.
Moda 10 Advances In Model Oriented Design And Analysis
DOWNLOAD
Author : Dariusz Ucinski
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-21
Moda 10 Advances In Model Oriented Design And Analysis written by Dariusz Ucinski and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-21 with Mathematics categories.
This book collects the proceedings of the 10th Workshop on Model-Oriented Design and Analysis (mODa). A model-oriented view on the design of experiments, which is the unifying theme of all mODa meetings, assumes some knowledge of the form of the data-generating process and naturally leads to the so-called optimum experimental design. Its theory and practice have since become important in many scientific and technological fields, ranging from optimal designs for dynamic models in pharmacological research, to designs for industrial experimentation, to designs for simulation experiments in environmental risk management, to name but a few. The methodology has become even more important in recent years because of the increased speed of scientific developments, the complexity of the systems currently under investigation and the mounting pressure on businesses, industries and scientific researchers to reduce product and process development times. This increased competition requires ever increasing efficiency in experimentation, thus necessitating new statistical designs. This book presents a rich collection of carefully selected contributions ranging from statistical methodology to emerging applications. It primarily aims to provide an overview of recent advances and challenges in the field, especially in the context of new formulations, methods and state-of-the-art algorithms. The topics included in this volume will be of interest to all scientists and engineers and statisticians who conduct experiments.
Biostatistics In Biopharmaceutical Research And Development
DOWNLOAD
Author : Ding-Geng Chen
language : en
Publisher: Springer Nature
Release Date : 2024-12-24
Biostatistics In Biopharmaceutical Research And Development written by Ding-Geng Chen and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-24 with Medical categories.
The Deming Conference on Applied Statistics has long been deemed an influential event in the biostatistics and biopharmaceutical profession. It provides learning experience on recent developments in statistical methodologies in biopharmaceutical applications and FDA regulations. This book honors 80 years of contributions and dedication of the Deming Conference in biostatistics, and biopharmaceutical clinical trial methodology and applications. All chapters are contributed by world-class and prominent Deming speakers, who've contributed their cutting-edge research and developments to the community. Volume 1 covers Historical Milestones in Clinical Trial Design, FDA biopharmaceutical design guidance, and emerging development in Clinical Trial Design Methodology. This book aims to booster research, education, and training in biostatistics and in biopharmaceutical research and development. Chapter "Response-adaptive Randomization Designs Based on Optimal Allocation Proportion" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Complex Data Modeling And Computationally Intensive Statistical Methods
DOWNLOAD
Author : Pietro Mantovan
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-01-27
Complex Data Modeling And Computationally Intensive Statistical Methods written by Pietro Mantovan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-27 with Computers categories.
Selected from the conference "S.Co.2009: Complex Data Modeling and Computationally Intensive Methods for Estimation and Prediction," these 20 papers cover the latest in statistical methods and computational techniques for complex and high dimensional datasets.
Optimal Experimental Design
DOWNLOAD
Author : Jesús López-Fidalgo
language : en
Publisher: Springer Nature
Release Date : 2023-09-12
Optimal Experimental Design written by Jesús López-Fidalgo and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-12 with Mathematics categories.
This textbook provides a concise introduction to optimal experimental design and efficiently prepares the reader for research in the area. It presents the common concepts and techniques for linear and nonlinear models as well as Bayesian optimal designs. The last two chapters are devoted to particular themes of interest, including recent developments and hot topics in optimal experimental design, and real-world applications. Numerous examples and exercises are included, some of them with solutions or hints, as well as references to the existing software for computing designs. The book is primarily intended for graduate students and young researchers in statistics and applied mathematics who are new to the field of optimal experimental design. Given the applications and the way concepts and results are introduced, parts of the text will also appeal to engineers and other applied researchers.
Handbook Of Methods For Designing Monitoring And Analyzing Dose Finding Trials
DOWNLOAD
Author : John O'Quigley
language : en
Publisher: CRC Press
Release Date : 2017-04-27
Handbook Of Methods For Designing Monitoring And Analyzing Dose Finding Trials written by John O'Quigley and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-27 with Mathematics categories.
Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of early phase studies. The need to accelerate drug development in a rapidly evolving context of targeted therapies, immunotherapy, combination treatments and complex group structures has provided the stimulus to these advances. Typically, we deal with very small samples, sequential methods that need to be efficient, while, at the same time adhering to ethical principles due to the involvement of human subjects. Statistical inference is difficult since the standard techniques of maximum likelihood do not usually apply as a result of model misspecification and parameter estimates lying on the boundary of the parameter space. Bayesian methods play an important part in overcoming these difficulties, but nonetheless, require special consideration in this particular context. The purpose of this handbook is to provide an expanded summary of the field as it stands and also, through discussion, provide insights into the thinking of leaders in the field as to the potential developments of the years ahead. With this goal in mind we present: An introduction to the field for graduate students and novices A basis for more established researchers from which to build A collection of material for an advanced course in early phase clinical trials A comprehensive guide to available methodology for practicing statisticians on the design and analysis of dose-finding experiments An extensive guide for the multiple comparison and modeling (MCP-Mod) dose-finding approach, adaptive two-stage designs for dose finding, as well as dose–time–response models and multiple testing in the context of confirmatory dose-finding studies. John O’Quigley is a professor of mathematics and research director at the French National Institute for Health and Medical Research based at the Faculty of Mathematics, University Pierre and Marie Curie in Paris, France. He is author of Proportional Hazards Regression and has published extensively in the field of dose finding. Alexia Iasonos is an associate attending biostatistician at the Memorial Sloan Kettering Cancer Center in New York. She has over one hundred publications in the leading statistical and clinical journals on the methodology and design of early phase clinical trials. Dr. Iasonos has wide experience in the actual implementation of model based early phase trials and has given courses in scientific meetings internationally. Björn Bornkamp is a statistical methodologist at Novartis in Basel, Switzerland, researching and implementing dose-finding designs in Phase II clinical trials. He is one of the co-developers of the MCP-Mod methodology for dose finding and main author of the DoseFinding R package. He has published numerous papers on dose finding, nonlinear models and Bayesian statistics, and in 2013 won the Royal Statistical Society award for statistical excellence in the pharmaceutical industry.
Surveys In Combinatorics 2017
DOWNLOAD
Author : Anders Claesson
language : en
Publisher: Cambridge University Press
Release Date : 2017-06-30
Surveys In Combinatorics 2017 written by Anders Claesson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-30 with Mathematics categories.
This book includes nine articles representing a timely snapshot of the state of the art in the different areas of combinatorics.
Modern Adaptive Randomized Clinical Trials
DOWNLOAD
Author : Oleksandr Sverdlov
language : en
Publisher: CRC Press
Release Date : 2015-06-30
Modern Adaptive Randomized Clinical Trials written by Oleksandr Sverdlov and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-30 with Mathematics categories.
Is adaptive randomization always better than traditional fixed-schedule randomization? Which procedures should be used and under which circumstances? What special considerations are required for adaptive randomized trials? What kind of statistical inference should be used to achieve valid and unbiased treatment comparisons following adaptive random
Modern Experimental Design
DOWNLOAD
Author : Thomas P. Ryan
language : en
Publisher: John Wiley & Sons
Release Date : 2007-02-02
Modern Experimental Design written by Thomas P. Ryan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-02 with Mathematics categories.
A complete and well-balanced introduction to modern experimental design Using current research and discussion of the topic along with clear applications, Modern Experimental Design highlights the guiding role of statistical principles in experimental design construction. This text can serve as both an applied introduction as well as a concise review of the essential types of experimental designs and their applications. Topical coverage includes designs containing one or multiple factors, designs with at least one blocking factor, split-unit designs and their variations as well as supersaturated and Plackett-Burman designs. In addition, the text contains extensive treatment of: Conditional effects analysis as a proposed general method of analysis Multiresponse optimization Space-filling designs, including Latin hypercube and uniform designs Restricted regions of operability and debarred observations Analysis of Means (ANOM) used to analyze data from various types of designs The application of available software, including Design-Expert, JMP, and MINITAB This text provides thorough coverage of the topic while also introducing the reader to new approaches. Using a large number of references with detailed analyses of datasets, Modern Experimental Design works as a well-rounded learning tool for beginners as well as a valuable resource for practitioners.