Modeling And Control Of Infectious Diseases In The Host
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Modeling And Control Of Infectious Diseases In The Host
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Author : Esteban A. Hernandez-Vargas
language : en
Publisher: Academic Press
Release Date : 2019-02-15
Modeling And Control Of Infectious Diseases In The Host written by Esteban A. Hernandez-Vargas and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-15 with Technology & Engineering categories.
Modeling and Control of Infectious Diseases in the Host: With MATLAB and R provides a holistic understanding of health and disease by presenting topics on quantitative decision-making that influence the development of drugs. The book presents modeling advances in different viral infections, dissecting detailed contributions of key players, along with their respective interactions. By combining tailored in vivo experiments and mathematical modeling approaches, the book clarifies the relative contributions of different underlying mechanisms within hosts of the most lethal viral infections, including HIV, influenza and Ebola. Illustrative examples for parameter fitting, modeling and control applications are explained using MATLAB and R. Provides a multi-scale framework to link within-host infection dynamics (individual level) to between-host transmission fitness (epidemiological level) in viral infectious diseases Includes PK/PD modeling and simulation approaches to improve efficiency and decision-making at preclinical development phases Presents a theoretic approach to schedule drug treatments
Modeling Infectious Diseases In Humans And Animals
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Author : Matt J. Keeling
language : en
Publisher: Princeton University Press
Release Date : 2011-09-19
Modeling Infectious Diseases In Humans And Animals written by Matt J. Keeling and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-19 with Science categories.
For epidemiologists, evolutionary biologists, and health-care professionals, real-time and predictive modeling of infectious disease is of growing importance. This book provides a timely and comprehensive introduction to the modeling of infectious diseases in humans and animals, focusing on recent developments as well as more traditional approaches. Matt Keeling and Pejman Rohani move from modeling with simple differential equations to more recent, complex models, where spatial structure, seasonal "forcing," or stochasticity influence the dynamics, and where computer simulation needs to be used to generate theory. In each of the eight chapters, they deal with a specific modeling approach or set of techniques designed to capture a particular biological factor. They illustrate the methodology used with examples from recent research literature on human and infectious disease modeling, showing how such techniques can be used in practice. Diseases considered include BSE, foot-and-mouth, HIV, measles, rubella, smallpox, and West Nile virus, among others. Particular attention is given throughout the book to the development of practical models, useful both as predictive tools and as a means to understand fundamental epidemiological processes. To emphasize this approach, the last chapter is dedicated to modeling and understanding the control of diseases through vaccination, quarantine, or culling. Comprehensive, practical introduction to infectious disease modeling Builds from simple to complex predictive models Models and methodology fully supported by examples drawn from research literature Practical models aid students' understanding of fundamental epidemiological processes For many of the models presented, the authors provide accompanying programs written in Java, C, Fortran, and MATLAB In-depth treatment of role of modeling in understanding disease control
Infectious Diseases Of Humans
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Author : Roy M. Anderson
language : en
Publisher: Oxford University Press
Release Date : 1991
Infectious Diseases Of Humans written by Roy M. Anderson and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.
This book deals with infectious diseases -- viral, bacterial, protozoan and helminth -- in terms of the dynamics of their interaction with host populations. The book combines mathematical models with extensive use of epidemiological and other data. This analytic framework is highly useful for the evaluation of public health strategies aimed at controlling or eradicating particular infections. Such a framework is increasingly important in light of the widespread concern for primary health care programs aimed at such diseases as measles, malaria, river blindness, sleeping sickness, and schistosomiasis, and the advent of AIDS/HIV and other emerging viruses. Throughout the book, the mathematics is used as a tool for thinking clearly about fundamental and applied problems having to do with infectious diseases. The book is divided into two parts, one dealing with microparasites (viruses, bacteria and protozoans) and the other with macroparasites (helminths and parasitic arthropods). Each part begins with simple models, developed in a biologically intuitive way, and then goes on to develop more complicated and realistic models as tools for public health planning. The book synthesizes previous work in this rapidly growing field (much of which is scattered between the ecological and the medical literature) with a good deal of new material.
Modeling Disease Spread And Control
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Author : Tariq Halasa
language : en
Publisher: Frontiers Media SA
Release Date : 2018-01-18
Modeling Disease Spread And Control written by Tariq Halasa and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with categories.
Mathematical models are useful tools to understand the epidemiology and agent-host interaction of diseases. They are developed and applied since over a century, but with increasing computer capacity, they become increasingly prominent as part of evidence based decision making. Mathematical models are frequently used to construct preparedness and contingency plans for highly contagious diseases such as foot-and-mouth disease. This allows proposing effective strategies to control the spread of the disease in case of an incursion, and avails useful tools to support decision making during an outbreak. They are also used to monitor, prevent and control endemic diseases within populations or farms. In addition, mathematical models improve our understanding of the contact structure between farms, pointing out risky elements in the contact network for disease introduction or further spread within the population. This Research Topic presents valuable studies presenting different aspects and implementations of mathematical modeling for disease spread and control in the veterinary field. The areas covered include model construction, network analysis, tools for decision makers, and costeffective control of endemic diseases.
Modelling Parasite Transmission And Control
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Author : Edwin Michael
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-12-31
Modelling Parasite Transmission And Control written by Edwin Michael and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-31 with Medical categories.
It is clear that many fascinating problems still remain to be addressed in parasite transmission modelling, from better understanding of transmission processes and natural history of infection to investigating the impact of ecological and spatial scales, climate change, host immunity and social behaviour, parasite-host evolutionary dynamics and parasite community ecology on parasite transmission. This book captures some of the advances made in recent years and provides indications of ways forward for addressing these questions by shedding light on developments in conceptual frameworks and modelling tools as well as the emergence of new data forms for aiding model construction, testing and analysis. Another important advance has been the parallel development of robust computationally-intensive statistical methods to allow model testing and parameterization by aiding the fitting of models to complex data. This is an exciting area of work, which we believe will broaden the scope of mathematical modelling in investigating parasite transmission processes. In particular, we expect this advance will now allow modellers to begin the successful development and analysis of mechanistically-rich models of parasite transmission that will facilitate better integration of the variety of mechanisms increasingly recognized as important in simultaneously affecting transmission, including abiotic processes, trophic and evolutionary interactions, movement in space, and behaviour and even physiology of the individual. We foresee a continuing bright future for using mathematical modelling to clarify parasite transmission dynamics and address problems related to effective parasite control. Ultimately, through this improved application of models to research and management, we expect that parasite control would be an achievable goal bringing benefits to a vast number of our fellow human beings.
Modeling The Transmission And Prevention Of Infectious Disease
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Author : Christon J. Hurst
language : en
Publisher: Springer
Release Date : 2017-08-31
Modeling The Transmission And Prevention Of Infectious Disease written by Christon J. Hurst and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-31 with Science categories.
This volume focuses on blocking disease transmission and the ecological perspective of pathogens and pathogenic processes. The chapters on blocking transmission cover the environmental safety of space flight, biocides and biocide resistance, as well as infection control in healthcare facilities. The book also offers insights into the ecological aspects of infectious disease, introducing the reader to the role of indigenous gut microbiota in maintaining human health and current discussions on environmentally encountered bacterial and fungal pathogens including species that variously cause the necrotizing skin disease Buruli ulcer and coccidioidomycosis. Further, it explores the influenza A virus as an example for understanding zoonosis. It is a valuable resource for microbiologists and biomedical scientists alike.
Epidemics
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Author : Ottar N. Bjørnstad
language : en
Publisher: Springer
Release Date : 2018-10-30
Epidemics written by Ottar N. Bjørnstad and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-30 with Medical categories.
This book is designed to be a practical study in infectious disease dynamics. The book offers an easy to follow implementation and analysis of mathematical epidemiology. The book focuses on recent case studies in order to explore various conceptual, mathematical, and statistical issues. The dynamics of infectious diseases shows a wide diversity of pattern. Some have locally persistent chains-of-transmission, others persist spatially in ‘consumer-resource metapopulations’. Some infections are prevalent among the young, some among the old and some are age-invariant. Temporally, some diseases have little variation in prevalence, some have predictable seasonal shifts and others exhibit violent epidemics that may be regular or irregular in their timing. Models and ‘models-with-data’ have proved invaluable for understanding and predicting this diversity, and thence help improve intervention and control. Using mathematical models to understand infectious disease dynamics has a very rich history in epidemiology. The field has seen broad expansions of theories as well as a surge in real-life application of mathematics to dynamics and control of infectious disease. The chapters of Epidemics: Models and Data using R have been organized in a reasonably logical way: Chapters 1-10 is a mix and match of models, data and statistics pertaining to local disease dynamics; Chapters 11-13 pertains to spatial and spatiotemporal dynamics; Chapter 14 highlights similarities between the dynamics of infectious disease and parasitoid-host dynamics; Finally, Chapters 15 and 16 overview additional statistical methodology useful in studies of infectious disease dynamics. This book can be used as a guide for working with data, models and ‘models-and-data’ to understand epidemics and infectious disease dynamics in space and time.
Modeling Disease Spread And Control
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Author :
language : en
Publisher:
Release Date : 2018
Modeling Disease Spread And Control written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
Mathematical models are useful tools to understand the epidemiology and agent-host interaction of diseases. They are developed and applied since over a century, but with increasing computer capacity, they become increasingly prominent as part of evidence based decision making. Mathematical models are frequently used to construct preparedness and contingency plans for highly contagious diseases such as foot-and-mouth disease. This allows proposing effective strategies to control the spread of the disease in case of an incursion, and avails useful tools to support decision making during an outbreak. They are also used to monitor, prevent and control endemic diseases within populations or farms. In addition, mathematical models improve our understanding of the contact structure between farms, pointing out risky elements in the contact network for disease introduction or further spread within the population. This Research Topic presents valuable studies presenting different aspects and implementations of mathematical modeling for disease spread and control in the veterinary field. The areas covered include model construction, network analysis, tools for decision makers, and cost-effective control of endemic diseases.
Modeling And Control Of Infectious Diseases In The Host
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Author : Esteban A. Hernandez-Vargas
language : en
Publisher: Academic Press
Release Date : 2019-02-14
Modeling And Control Of Infectious Diseases In The Host written by Esteban A. Hernandez-Vargas and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-14 with Technology & Engineering categories.
Modeling and Control of Infectious Diseases in the Host: With MATLAB and R provides a holistic understanding of health and disease by presenting topics on quantitative decision-making that influence the development of drugs. The book presents modeling advances in different viral infections, dissecting detailed contributions of key players, along with their respective interactions. By combining tailored in vivo experiments and mathematical modeling approaches, the book clarifies the relative contributions of different underlying mechanisms within hosts of the most lethal viral infections, including HIV, influenza and Ebola. Illustrative examples for parameter fitting, modeling and control applications are explained using MATLAB and R. Provides a multi-scale framework to link within-host infection dynamics (individual level) to between-host transmission fitness (epidemiological level) in viral infectious diseases Includes PK/PD modeling and simulation approaches to improve efficiency and decision-making at preclinical development phases Presents a theoretic approach to schedule drug treatments
Applications Of Epidemiological Models To Public Health Policymaking
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Author : Zhilan Feng
language : en
Publisher: World Scientific
Release Date : 2014
Applications Of Epidemiological Models To Public Health Policymaking written by Zhilan Feng and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Medical categories.
Mathematical models can be very helpful to understand the transmission dynamics of infectious diseases. This book presents examples of epidemiological models and modeling tools that can assist policymakers to assess and evaluate disease control strategies. Contents: Development and Analysis of Models for Infectious Diseases; Application of Models to Real Disease Data; User-Friendly Modeling Tools for Public Health Policymakers. Readership: Researchers in mathematical biology, mathematical modeling, infectious diseases and complex systems.