Modeling Cellular Systems
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Modeling Cellular Systems
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Author : Frederik Graw
language : en
Publisher: Springer
Release Date : 2017-05-08
Modeling Cellular Systems written by Frederik Graw and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-08 with Technology & Engineering categories.
This contributed volume comprises research articles and reviews on topics connected to the mathematical modeling of cellular systems. These contributions cover signaling pathways, stochastic effects, cell motility and mechanics, pattern formation processes, as well as multi-scale approaches. All authors attended the workshop on "Modeling Cellular Systems" which took place in Heidelberg in October 2014. The target audience primarily comprises researchers and experts in the field, but the book may also be beneficial for graduate students.
Introduction To Modeling Biological Cellular Control Systems
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Author : Weijiu Liu
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-04-26
Introduction To Modeling Biological Cellular Control Systems written by Weijiu Liu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-26 with Mathematics categories.
This textbook contains the essential knowledge in modeling, simulation, analysis, and applications in dealing with biological cellular control systems. In particular, the book shows how to use the law of mass balance and the law of mass action to derive an enzyme kinetic model - the Michaelis-Menten function or the Hill function, how to use a current-voltage relation, Nernst potential equilibrium equation, and Hodgkin and Huxley's models to model an ionic channel or pump, and how to use the law of mass balance to integrate these enzyme or channel models into a complete feedback control system. The book also illustrates how to use data to estimate parameters in a model, how to use MATLAB to solve a model numerically, how to do computer simulations, and how to provide model predictions. Furthermore, the book demonstrates how to conduct a stability and sensitivity analysis on a model.
The Regulation Of Cellular Systems
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Author : Reinhart Heinrich
language : en
Publisher: Taylor & Francis US
Release Date : 1996-08-31
The Regulation Of Cellular Systems written by Reinhart Heinrich and has been published by Taylor & Francis US this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-08-31 with Gardening categories.
This book deals with problems and approaches to cellular systems and will cover a wide range of cell types and cell systems, including nerve cells. It will be of interest to cell biologists interested in modeling, and to any students interested in the field. It will also apppeal to the theoretical and mathematical biology community, and would have relevance to individuals interested in evolutionary issues as they bear on cellular metabolic models. It will be a solid theoretical book, with an empirical base and an evolution connection, that fits exactly to the initial theme of the theoretical biology series.
Cellular Automaton Modeling Of Biological Pattern Formation
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Author : Andreas Deutsch
language : en
Publisher: Birkhäuser
Release Date : 2018-03-09
Cellular Automaton Modeling Of Biological Pattern Formation written by Andreas Deutsch and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-09 with Mathematics categories.
This text explores the use of cellular automata in modeling pattern formation in biological systems. It describes several mathematical modeling approaches utilizing cellular automata that can be used to study the dynamics of interacting cell systems both in simulation and in practice. New in this edition are chapters covering cell migration, tissue development, and cancer dynamics, as well as updated references and new research topic suggestions that reflect the rapid development of the field. The book begins with an introduction to pattern-forming principles in biology and the various mathematical modeling techniques that can be used to analyze them. Cellular automaton models are then discussed in detail for different types of cellular processes and interactions, including random movement, cell migration, adhesive cell interaction, alignment and cellular swarming, growth processes, pigment cell pattern formation, tissue development, tumor growth and invasion, and Turing-type patterns and excitable media. In the final chapter, the authors critically discuss possibilities and limitations of the cellular automaton approach in modeling various biological applications, along with future research directions. Suggestions for research projects are provided throughout the book to encourage additional engagement with the material, and an accompanying simulator is available for readers to perform their own simulations on several of the models covered in the text. QR codes are included within the text for easy access to the simulator. With its accessible presentation and interdisciplinary approach, Cellular Automaton Modeling of Biological Pattern Formation is suitable for graduate and advanced undergraduate students in mathematical biology, biological modeling, and biological computing. It will also be a valuable resource for researchers and practitioners in applied mathematics, mathematical biology, computational physics, bioengineering, and computer science. PRAISE FOR THE FIRST EDITION “An ideal guide for someone with a mathematical or physical background to start exploring biological modelling. Importantly, it will also serve as an excellent guide for experienced modellers to innovate and improve their methodologies for analysing simulation results.” —Mathematical Reviews
Statistical Mechanics Of Cellular Systems And Processes
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Author : Muhammad H. Zaman
language : en
Publisher: Cambridge University Press
Release Date : 2009-03-26
Statistical Mechanics Of Cellular Systems And Processes written by Muhammad H. Zaman and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-26 with Science categories.
Cells are complex objects, representing a multitude of structures and processes. In order to understand the organization, interaction and hierarchy of these structures and processes, a quantitative understanding is absolutely critical. Traditionally, statistical mechanics-based treatment of biological systems has focused on the molecular level, with larger systems being ignored. This book integrates understanding from the molecular to the cellular and multi-cellular level in a quantitative framework that will benefit a wide audience engaged in biological, biochemical, biophysical and clinical research. It will build new bridges of quantitative understanding that link fundamental physical principles governing cellular structure and function with implications in clinical and biomedical contexts.
Mathematical Modeling In Systems Biology
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Author : Brian P. Ingalls
language : en
Publisher: MIT Press
Release Date : 2022-06-07
Mathematical Modeling In Systems Biology written by Brian P. Ingalls and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-07 with Science categories.
An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.
Quantitative Biology
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Author : Michael E. Wall
language : en
Publisher: CRC Press
Release Date : 2012-08-25
Quantitative Biology written by Michael E. Wall and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-25 with Science categories.
Quantitative methods are revolutionizing modern molecular and cellular biology. Groundbreaking technical advances are fueling the rapid expansion in our ability to observe, as seen in multidisciplinary studies that integrate theory, computation, experimental assays, and the control of microenvironments. Integrating new experimental and theoretical methods, Quantitative Biology: From Molecular to Cellular Systems gives both new and established researchers a solid foundation for starting work in this field. The book is organized into three sections: Fundamental Concepts covers bold ideas that inspire novel approaches in modern quantitative biology. It offers perspectives on evolutionary dynamics, system design principles, chance and memory, and information processing in biology. Methods describes recently developed or improved techniques that are transforming biological research. It covers experimental methods for studying single-molecule biochemistry, small-angle scattering from biomolecules, subcellular localization of proteins, and single-cell behavior. It also describes theoretical methods for synthetic biology and modeling random variations among cells. Molecular and Cellular Systems focuses on specific biological systems where modern quantitative biology methods are making an impact. It incorporates case studies of biological systems for which new concepts or methods are increasing our understanding. Examples include protein kinase at the molecular level, the genetic switch of phage lambda at the regulatory system level, and Escherichia coli chemotaxis at the cellular level. In short, Quantitative Biology presents practical tools for the observation, modeling, design, and manipulation of biological systems from the molecular to the cellular levels.
Cellular Biophysics And Modeling
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Author : Greg Conradi Smith
language : en
Publisher: Cambridge University Press
Release Date : 2019-03-14
Cellular Biophysics And Modeling written by Greg Conradi Smith and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-14 with Mathematics categories.
What every neuroscientist should know about the mathematical modeling of excitable cells, presented at an introductory level.
Cellular Automata Modeling Of Physical Systems
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Author : Bastien Chopard
language : en
Publisher: Cambridge University Press
Release Date : 1998-12-10
Cellular Automata Modeling Of Physical Systems written by Bastien Chopard and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-12-10 with Computers categories.
Self-contained, pedagogic introduction to powerful techniques for graduate students and researchers in physics and computer science.
An Introduction To Computational Systems Biology
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Author : Karthik Raman
language : en
Publisher: Chapman & Hall/CRC
Release Date : 2023-05-29
An Introduction To Computational Systems Biology written by Karthik Raman and has been published by Chapman & Hall/CRC this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-29 with Biological systems categories.
Emphasises a hands-on approach to modelling Strong emphasis on coding and software tools for systems biology Covers the entire spectrum of modelling, from static networks, to dynamic models Thoughtful exercises to test and enable student understanding of concepts Current chapters on exciting new developments like whole-cell modelling and community modelling