Modeling In Computational Biology And Biomedicine
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Modeling In Computational Biology And Biomedicine
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Author : Frédéric Cazals
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-06
Modeling In Computational Biology And Biomedicine written by Frédéric Cazals and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-06 with Mathematics categories.
Computational biology, mathematical biology, biology and biomedicine are currently undergoing spectacular progresses due to a synergy between technological advances and inputs from physics, chemistry, mathematics, statistics and computer science. The goal of this book is to evidence this synergy by describing selected developments in the following fields: bioinformatics, biomedicine and neuroscience. This work is unique in two respects - first, by the variety and scales of systems studied and second, by its presentation: Each chapter provides the biological or medical context, follows up with mathematical or algorithmic developments triggered by a specific problem and concludes with one or two success stories, namely new insights gained thanks to these methodological developments. It also highlights some unsolved and outstanding theoretical questions, with a potentially high impact on these disciplines. Two communities will be particularly interested in this book. The first one is the vast community of applied mathematicians and computer scientists, whose interests should be captured by the added value generated by the application of advanced concepts and algorithms to challenging biological or medical problems. The second is the equally vast community of biologists. Whether scientists or engineers, they will find in this book a clear and self-contained account of concepts and techniques from mathematics and computer science, together with success stories on their favorite systems. The variety of systems described represents a panoply of complementary conceptual tools. On a practical level, the resources listed at the end of each chapter (databases, software) offer invaluable support for getting started on a specific topic in the fields of biomedicine, bioinformatics and neuroscience.
Single Cell Based Models In Biology And Medicine
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Author : Alexander Anderson
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-07
Single Cell Based Models In Biology And Medicine written by Alexander Anderson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-07 with Mathematics categories.
Many different single-cell-based models have been developed and applied to biological and medical problems. Computational approaches used are Monte-Carlo simulations, energy minimisation techniques, volume conservation laws, solutions of the equations of motion for each individual cell or for each point on the cell membrane. They differ in the level of detail that defines the cell structure and subsequently in the number of individual cells that the model can incorporate. This volume presents a collection of mathematical and computational single-cell-based models and their application. The main sections cover four general model groupings: hybrid cellular automata, cellular potts, lattice-free cells, and viscoelastic cells. Each section is introduced by a discussion of the applicability of the particular modelling approach and its advantages and disadvantages, which will make the book suitable for students starting research in mathematical biology as well as scientists modelling multicellular processes.
Modeling In Computational Biology And Biomedicine
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Author : D. Ric Cazals
language : en
Publisher:
Release Date : 2012-11-08
Modeling In Computational Biology And Biomedicine written by D. Ric Cazals and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-08 with categories.
Systems Biomedicine
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Author : Edison T. Liu
language : en
Publisher: Academic Press
Release Date : 2009-09-17
Systems Biomedicine written by Edison T. Liu and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-17 with Science categories.
Systems biology is a critical emerging field that quantifies and annotates the complexity of biological systems in order to construct algorithmic models to predict outcomes from component input. Applications in medicine are revolutionizing our understanding of biological processes and systems. Systems Biomedicine is organized around foundations, computational modeling, network biology, and integrative biology, with the extension of examples from human biology and pharmacology, to focus on the applications of systems approaches to medical problems. An integrative approach to the underlying genomic, proteomic, and computational biology principles provides researchers with guidance in the use of qualitative systems and hypothesis generators. To reflect the highly interdisciplinary nature of the field, careful detail has been extended to ensure explanations of complex mathematical and biological principles are clear with minimum technical jargon. - Organized to reflect the important distinguishing characteristics of systems strategies in experimental biology and medicine - Provides precise and comprehensive measurement tools for constructing a model of the system and tools for defining complexity as an experimental dependent variable - Includes a thorough discussion of the applications of quantitative principles to biomedical problems
Modeling In Systems Biology
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Author : Ina Koch
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-10-21
Modeling In Systems Biology written by Ina Koch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-21 with Computers categories.
The emerging, multi-disciplinary field of systems biology is devoted to the study of the relationships between various parts of a biological system, and computer modeling plays a vital role in the drive to understand the processes of life from an holistic viewpoint. Advancements in experimental technologies in biology and medicine have generated an enormous amount of biological data on the dependencies and interactions of many different molecular cell processes, fueling the development of numerous computational methods for exploring this data. The mathematical formalism of Petri net theory is able to encompass many of these techniques. This essential text/reference presents a comprehensive overview of cutting-edge research in applications of Petri nets in systems biology, with contributions from an international selection of experts. Those unfamiliar with the field are also provided with a general introduction to systems biology, the foundations of biochemistry, and the basics of Petri net theory. Further chapters address Petri net modeling techniques for building and analyzing biological models, as well as network prediction approaches, before reviewing the applications to networks of different biological classification. Topics and features: investigates the modular, qualitative modeling of regulatory networks using Petri nets, and examines an Hybrid Functional Petri net simulation case study; contains a glossary of the concepts and notation used in the book, in addition to exercises at the end of each chapter; covers the topological analysis of metabolic and regulatory networks, the analysis of models of signaling networks, and the prediction of network structure; provides a biological case study on the conversion of logical networks into Petri nets; discusses discrete modeling, stochastic modeling, fuzzy modeling, dynamic pathway modeling, genetic regulatory network modeling, and quantitative analysis techniques; includes a Foreword by Professor Jens Reich, Professor of Bioinformatics at Humboldt University and Max Delbrück Center for Molecular Medicine in Berlin. This unique guide to the modeling of biochemical systems using Petri net concepts will be of real utility to researchers and students of computational biology, systems biology, bioinformatics, computer science, and biochemistry.
Probabilistic Modeling In Bioinformatics And Medical Informatics
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Author : Dirk Husmeier
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-05-06
Probabilistic Modeling In Bioinformatics And Medical Informatics written by Dirk Husmeier and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-05-06 with Computers categories.
Probabilistic Modelling in Bioinformatics and Medical Informatics has been written for researchers and students in statistics, machine learning, and the biological sciences. The first part of this book provides a self-contained introduction to the methodology of Bayesian networks. The following parts demonstrate how these methods are applied in bioinformatics and medical informatics. All three fields - the methodology of probabilistic modeling, bioinformatics, and medical informatics - are evolving very quickly. The text should therefore be seen as an introduction, offering both elementary tutorials as well as more advanced applications and case studies.
Modelling Methodology For Physiology And Medicine
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Author : Ewart Carson
language : en
Publisher: Elsevier
Release Date : 2000-12-31
Modelling Methodology For Physiology And Medicine written by Ewart Carson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-12-31 with Mathematics categories.
Modelling Methodology for Physiology and Medicine offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modelling methodology that is widely applicable to physiology and medicine. The book opens with a clear and integrated treatment of advanced methodology for developing mathematical models of physiology and medical systems. Readers are then shown how to apply this methodology beneficially to real-world problems in physiology and medicine, such as circulation and respiration. - Builds upon and enhances the readers existing knowledge of modelling methodology and practice - Editors are internationally renowned leaders in their respective fields
Modelling In Medicine And Biology Viii
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Author : C. A. Brebbia
language : en
Publisher: WIT Press
Release Date : 2009
Modelling In Medicine And Biology Viii written by C. A. Brebbia and has been published by WIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Technology & Engineering categories.
Featuring contributions from the eighth International Conference on Modelling in Medicine and Biology, this volume covers a broad spectrum of topics including the application of computers to simulate biomedical phenomena. It will be of interest to medical and physical scientists and engineers.
Mathematical Modeling Of Biological Processes
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Author : Avner Friedman
language : en
Publisher: Springer
Release Date : 2014-09-19
Mathematical Modeling Of Biological Processes written by Avner Friedman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-19 with Mathematics categories.
This book on mathematical modeling of biological processes includes a wide selection of biological topics that demonstrate the power of mathematics and computational codes in setting up biological processes with a rigorous and predictive framework. Topics include: enzyme dynamics, spread of disease, harvesting bacteria, competition among live species, neuronal oscillations, transport of neurofilaments in axon, cancer and cancer therapy, and granulomas. Complete with a description of the biological background and biological question that requires the use of mathematics, this book is developed for graduate students and advanced undergraduate students with only basic knowledge of ordinary differential equations and partial differential equations; background in biology is not required. Students will gain knowledge on how to program with MATLAB without previous programming experience and how to use codes in order to test biological hypothesis.