Modeling Neurodegeneration In Yeast
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Modeling Neurodegeneration In Yeast
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Author : Ralf J. Braun
language : en
Publisher: Frontiers Media SA
Release Date : 2021-10-21
Modeling Neurodegeneration In Yeast written by Ralf J. Braun and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-21 with Science categories.
Tdp 43 And Neurodegeneration
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Author : Vijay Kumar
language : en
Publisher: Academic Press
Release Date : 2021-10-23
Tdp 43 And Neurodegeneration written by Vijay Kumar and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-23 with Medical categories.
Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43's structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases. This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders. - Reviews TDP-43 structure, folding, function, and pathology - Identifies TDP-43 role in ALS, FTP, and other neurodegenerative diseases - Presents a systems and precision biology perspective of TDP-43 - Discusses therapeutics of TDP-43 proteinopathies - Translates bench research to application bedside
Molecular Biology Of Neurodegenerative Diseases Visions For The Future
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-11-05
Molecular Biology Of Neurodegenerative Diseases Visions For The Future written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-05 with Science categories.
Molecular Biology of Neurodegenerative Diseases: Visions for the Future, Volume 168 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Alzheimer's disease, Prion-like propagation of alpha-synuclein, What - if anything - can we learn about neurodegenerative diseases from yeast?, Mitochondrial rejuvenation and replacement as a novel strategy for treatment of age-related neurodegenerative diseases, Propagation and removal of cerebral amyloid angiopathy, and much more. - Includes comprehensive coverage of molecular biology - Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided - Contains contributions from renowned experts in the field
Molecular Biology Of Neurodegenerative Diseases
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Author :
language : en
Publisher: Academic Press
Release Date : 2012-05-22
Molecular Biology Of Neurodegenerative Diseases written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-22 with Science categories.
Neurodegenerative diseases result in progressive degeneration and / or death of nerve cells which leads to problems with movement and mental functioning. Examples include Parkinson's, Alzheimer's and Huntington's disease. Much research is taking place to try to identify ways to prevent or lessen the impact of these diseases. This volume reviews the latest research and developments in the molecular biology of neurodegenerative diseases. - Contributions from leading authorities - Informs and updates on all the latest developments in the field
Yeasts In Biotechnology And Human Health
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Author : Isabel Sá-Correia
language : en
Publisher: Springer
Release Date : 2019-03-25
Yeasts In Biotechnology And Human Health written by Isabel Sá-Correia and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-25 with Science categories.
This book discusses genome-based strategies to provide a holistic understanding of yeasts in Human Health and as model organisms in basic research or industrial production. Using numerous Saccharomyces cerevisiae strains and various non-conventional yeast species isolated from diverse origins, it describes essential biological processes, the biotechnological exploitation of yeast and pathogenesis control. It also demonstrates how functional and comparative genomics and the development of genome engineering tools are used in modern yeast research. The use of yeasts as experimental eukaryotic models increasingly gained prominence when several Nobel Prizes in Physiology/Medicine and Chemistry were awarded for innovative research, using yeast strains to elucidate molecular mechanisms in a wide range of human physiological processes and diseases, such as autophagy, cell cycle regulation and telomerase activity. This book offers useful insights for scientists in yeast research, clinical scientists working with yeast infectious models and for industrial researchers using applied microbiology.
Molecular Chaperones And Neurodegeneration
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Author : Cintia Roodveldt
language : en
Publisher: Frontiers Media SA
Release Date : 2017-12-06
Molecular Chaperones And Neurodegeneration written by Cintia Roodveldt and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-06 with categories.
Molecular chaperones or heat-shock proteins (HSPs) play essential roles in safeguarding structural stability and preventing misfolding and aggregation of proteins, and maintaining the proteome functionality in the cell. For over two decades until the present time, new functions have been discovered and several molecular mechanisms have been elucidated for many chaperones, while the field is being continuously challenged by new open questions. Probably as a consequence of the increasing research on the molecular bases of neurodegenerative diseases, and the realisation that many such disorders are linked to protein misfolding processes, unleashing the roles and mechanisms of chaperones in the context of neurodegeneration has become a prime scientific goal. This e-book contains a diversity of reviews, perspective and original research articles highlighting the importance and potential of this emerging subject.
Small Molecules In Neurodegeneration
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Author : Nawab John Dar
language : en
Publisher: CRC Press
Release Date : 2025-03-13
Small Molecules In Neurodegeneration written by Nawab John Dar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-13 with Medical categories.
Neurodegenerative diseases, like Alzheimer's, Parkinson's, and Huntington's, cast a long shadow over millions of lives, stealing memories, independence, and futures. The rising tide of these age-related disorders threatens to overwhelm healthcare systems worldwide, prompting an urgent search for effective treatments. While current options offer temporary relief, they fail to halt the relentless march of these devastating conditions. However, a beacon of hope shines at the intersection of cutting-edge neuroscience and the world of small molecules. These tiny chemical warriors, with their inherent advantages of cost-effectiveness, scalability, and diverse functionalities, are emerging as powerful weapons in the fight against neurodegeneration. This book stands as a testament to this increasing revolution. It investigates deep into the intricacies of small molecules, exploring their potential to unravel the mysteries of neurodegenerative diseases and pave the way for innovative therapeutic interventions. Key Features: Provides a comprehensive and accessible overview of the emerging field of small molecules in neurodegenerative diseases. Bridges the gap in current literature by addressing the specific impact of small molecules on these devastating conditions. Offers an in-depth exploration of the various mechanisms by which small molecules can combat neurodegeneration. Serves as a valuable resource for a wide audience, from students to professionals in the field. Lays the foundation for a deeper understanding of neurodegenerative diseases and unlocks new avenues for the development of effective therapies.
Fungal Genomics
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Author : Minou Nowrousian
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-03-24
Fungal Genomics written by Minou Nowrousian and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-24 with Science categories.
The volume is divided into four sections, the first of which, Genome Sequences and Beyond, illustrates the impact of genome-based information and techniques on research ranging from model organisms like yeast to less-studied basal fungal lineages. Furthermore, it highlights novel types of analysis made possible by multi-genome comparisons as well as the impact of genomics on culture collections and vice versa. The second section, Cell and Developmental Biology, addresses questions that are important for fungal biology, e.g. the development of fungal fruiting bodies, and biology in general, e.g. chromatin organization and circadian rhythms. The third section, Genomics for Biotechnology, covers the search for plant biomass-converting enzymes in fungal genomes and work with industrially important fungi. The fourth section, focusing on Pathogenicity, offers chapters on the genomic analysis of plant and animal/human pathogens. It illustrates how genomics at all levels, from genome to metabolome, is used to study mechanisms of the interactions of fungi with other organisms.
Stem Cells In Neurodegeneration Disease Modeling And Therapeutics
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Author : Kim A. Staats
language : en
Publisher: Frontiers Media SA
Release Date : 2021-08-17
Stem Cells In Neurodegeneration Disease Modeling And Therapeutics written by Kim A. Staats and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-17 with Science categories.
Animal Models For Neurodegenerative Disease
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Author : Jesús Avila
language : en
Publisher: Royal Society of Chemistry
Release Date : 2011
Animal Models For Neurodegenerative Disease written by Jesús Avila and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
In recent years, medical developments have resulted in an increase in human life expectancy. The editors have extensive knowledge and experience in this field and the book is aimed at undergraduates, postgraduates, and academics. The chapters cover Alzheimer's disease, Parkinson's disease, Huntington's, and other neurodegenerative disorders.