Modeling Of Blood Flow In Stenosed Lad Coronary Artery
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Modeling Of Blood Flow In Stenosed Lad Coronary Artery
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Author : Zahraa A. Al-Saffar
language : en
Publisher: LAP Lambert Academic Publishing
Release Date : 2013
Modeling Of Blood Flow In Stenosed Lad Coronary Artery written by Zahraa A. Al-Saffar and has been published by LAP Lambert Academic Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.
Atherosclerosis is the most common causes of vascular diseases.So;looking for the physical factors and correlations that explain the phenomena of existence the atherosclerosis disease in LAD artery in some people rather than the others is achieved in this study by analysis data from coronary angiography as well as estimating the blood velocity from coronary angiography scans without having a required data on velocity by using some mathematical equations and physical laws. It found some information that may explain the ability of small arteries to develop the lesions with time mainly in proximal site of LAD artery. For investigation the fluid-structural response to pulsatile Newtonian and non-Newtonian blood flow through an axisymmetric stenosed coronary artery;the simulation is built up by using ANSYS11 to evaluate the biomechanical parameters in the atherosclerotic process. Rigid and Newtonian cases were investigated to provide an understanding on the effects of incorporating Fluid-Structural Interaction (FSI) into model. non-Newtonian Carreau model was investigated with FSI. For validation of the models and methods used, the computation results are compared with previous studies.
Cfd Analysis Of Blood Flow Through Stenosed Arteries
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Author : Narmada Surigala
language : en
Publisher:
Release Date : 2015
Cfd Analysis Of Blood Flow Through Stenosed Arteries written by Narmada Surigala and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Femoral artery categories.
The pathological complications of atherosclerosis, namely heart disease and stroke, remain the leading cause of mortality in the world. Cardiovascular illness is highly prevalent among the American population. One manifesto of cardiovascular disease is Peripheral Artery Disease (PAD) which is caused by atherosclerosis in the arteries. Atherosclerosis is a vascular disease that reduces arterial lumen size through plaque deposition and arterial wall thickening. The flow patterns in the arteries are highly modulating along with the cardiac cycle and a strong function of the waveform created by the heartbeat. In this study, a computational simulation model is developed to analyze blood flow distribution in a femoral artery network based on Navier-Stokes equation. A comparative analysis of blood flow through femoral artery is done based on Newtonian and non-Newtonian blood flow by using Carreau-Yasuda model subjected to a waveform based on a cardiac cycle. The non-Newtonian CFD flow analysis model is use to analyze blood flow distributions in a femoral artery along with the adjacent capillary porous tissue medium. This simulation model is used to analyze the flow and stress field in a healthy and atherosclerosis affected femoral arteries. Velocity, pressure and Wall Shear Stress fields over cardiac cycle are analyzed to demonstrate that adverse flow field created upstream and downstream of the blockage that may cause enhanced growth in size of the blockage.
Regulation Of Coronary Blood Flow
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Author : Michitoshi Inoue
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-09
Regulation Of Coronary Blood Flow written by Michitoshi Inoue and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-09 with Medical categories.
Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
Numerical Modeling Of Blood Flow In Human Left Coronary Artery And In Vitro Study Of Endothelial Cell Activation By Shear Stress
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Author : Saravan Kumar Shanmugavelayudam
language : en
Publisher:
Release Date : 2009
Numerical Modeling Of Blood Flow In Human Left Coronary Artery And In Vitro Study Of Endothelial Cell Activation By Shear Stress written by Saravan Kumar Shanmugavelayudam and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Panvascular Medicine
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Author : Peter Lanzer
language : en
Publisher: Springer
Release Date : 2015-03-30
Panvascular Medicine written by Peter Lanzer and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-30 with Medical categories.
Vascular management and care has become a truly multidisciplinary enterprise as the number of specialists involved in the treatment of patients with vascular diseases has steadily increased. While in the past, treatments were delivered by individual specialists, in the twenty-first century a team approach is without doubt the most effective strategy. In order to promote professional excellence in this dynamic and rapidly evolving field, a shared knowledge base and interdisciplinary standards need to be established. Pan Vascular Medicine, 2nd edition has been designed to offer such an interdisciplinary platform, providing vascular specialists with state-of-the art descriptive and procedural knowledge. Basic science, diagnostics, and therapy are all comprehensively covered. In a series of succinct, clearly written chapters, renowned specialists introduce and comment on the current international guidelines and present up-to-date reviews of all aspects of vascular care.
Numerical Simulation Of Blood Flow In Arterial Stenosis Under Steady And Pulsatile Flow Conditions
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Author : Parth Pranavbhai Dave
language : en
Publisher:
Release Date : 2011
Numerical Simulation Of Blood Flow In Arterial Stenosis Under Steady And Pulsatile Flow Conditions written by Parth Pranavbhai Dave and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Electronic dissertations categories.
Cardiovascular diseases (CVDs) are among the leading causes of death in the world. In this study, an attempt was made to model the flow dynamics of blood in abnormally narrowed artery. Finite volume solver FLUENT was used for the analysis with the aim of understanding the consequences of increasing the degree of stenosis using a two-equation turbulence model. The compliant nature of the artery was neglected, and Newtonian behavior of the blood flow was assumed for the larger arteries. Steady-flow simulations with 75% area reductions were used to establish the validity of the current models by employing the standard and transitional variant of the k -w turbulence models. Subsequently, it was found that transitional k -w model was suitable for the low Reynolds number internal flows associated with the transition to turbulence, although only a minor departure in terms of the turbulence intensity peak was observed. Unsteady blood flow was introduced by employing a sinusoidal pulsatile waveform at the inlet. The pulsatile nature of the blood flow was investigated in the range of the constriction ratio from 60% to 90%, with an inlet-specified pulse. It was hypothesized that the severity of the stenosis played a major role in the initiation of the turbulence, since no major turbulence was reported for the 60% and 75% area reductions, while increasing the constriction ratio of 90% significantly altered the flow dynamics and triggered the transition to turbulence much earlier than anticipated. The outcome of current numerical efforts was expressed in terms of wall shear stress, a hemodynamically relevant parameter.
Coronary Pressure
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Author : N.H. Pijls
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Coronary Pressure written by N.H. Pijls and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
Cardiologists must answer three important questions when evaluating and treating patients with a coronary artery stenosis. As a physiologist: "What is the effect of this stenosis on coronary blood flow and myocardial function?"; as a clinician: " Is this lesion responsible for the patient's symptoms?"; and finally as an interventionalist: "Will revascularization of this artery improve the patient?" Fundamentally, the answer to these questions can be given to a large extent by measuring coronary pressure. That is the rationale of writing this book. 1. 1 Historical overview. Andreas Gruentzig and most interventional cardiologists in the early days of PTCA, had the intuitive feeling that pressure measurements could help to establish the severity of a coronary stenosis and to monitor the progress and result of a coronary intervention. At that time, measuring coronary pressure by the balloon catheter was part of a standard procedure. A residual transstenotic gradient of less than 15 mmHg was generally considered as a good result. Later, however, it turned out that measuring these (resting) gradients with balloon catheters was inaccurate an only had a limited prognostic value. Moreover, because there was no consistent theory to correlate pressure measurements to blood flow, the interest in measuring coronary pressures faded and disappeared almost completely with the introduction of new balloon catheters not intended for pressure measurement.
Characterization Of Physiological Flow In Stenosed And Stented Coronary Artery Bifurcations
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Author : Marjan Molavi-Zarandi
language : en
Publisher:
Release Date : 2013
Characterization Of Physiological Flow In Stenosed And Stented Coronary Artery Bifurcations written by Marjan Molavi-Zarandi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.
"Myocardial infarction (MI) is a severe form of heart disease caused by the blockage of coronary arteries. Percutaneous coronary angioplasty of coronary artery bifurcation is associated with complications. The Medina classification is used by physicians to categorize the bifurcation lesions. However, the Medina classification is an anatomical classification which does not discriminate the complex disease. For example, there are reported cases, which are still unexplained, implying that there is anatomically significant appearance of a coronary stenosis in bifurcation disease detected by coronary angiography, intravascular ultrasound measurement (IVUS) and quantitative coronary angiography (QCA) which does not correlate with standard fractional flow reserve (FFR) measurement (Ben-Dor et al. 2011, Koo et al. 2005, Sarno et al. 2009, Meijboom et al. 2008, Ziaee et al. 2004). As another problem, there are some reports that patients may develop clinically significant myocardial ischemia from coronary artery steal (Kosar et al. 2009). The functional state of a patient with stenosis can be determined by coronary flow, pressure and other biomechanical parameters like wall shear stress (WSS). The characterization of physiological flow on the basis of functional and biomechanical parameters is essential to assess the intuitiveness of the Medina classification and to be able to identify the riskier disease to employ the most effective treatment strategy. However, the impacts of the bifurcation angle, location of stenoses and their percentages have not systematically been studied in stenosed bifurcation with respect to a classification scheme. To this end, computational models of normal and stenosed coronary artery bifurcations are developed and physiological flow are studied. The effect of percentage of stenosis, lesion length and location is determined aiming at deriving a functionally base classification scheme that could resolve the above mentioned clinical observations. The results of this work showed that in true bifurcation lesions, the lower blood flow in the Side Branch (SB) creates a critical condition for this branch in bifurcation lesion (1, 0, 1) compared to bifurcation lesions (1, 1, 1) and (0, 1, 1) respectively. It should be noted that bifurcation lesion (1, 0, 1) corresponds to the steal condition. Occlusion of the SB is an important contributing factor in increasing the MI rate. Our results demonstrated that the non-stenotic main branch distal steals flow away from the artery in the presence of a proximal main branch and side branch stenoses. Stenosed bifurcation (1, 0, 1) leads to increase flow disturbance in the SB associated with low WSS. Examination of degree and location of stenoses and the SB angle showed the degrees of stenosis and the plaque location have more effect on the blood flow ratio and WSS distribution. A new classification scheme was proposed to make it functional as a global scheme for the assessment of coronary bifurcation lesions.Treatment of coronary bifurcation lesions is mostly performed by stent implantation. The key in the treatment of bifurcations lesion is the SB. Several stenting techniques are used for bifurcation stenting. Direct comparisons of different strategies and their outcomes remain limited. In this work computational models of normal and stented coronary artery bifurcations are developed and the influence of two stent configurations on alteration of WSS in the stented vessel is studied. Comparison of two stenting techniques showed that the deployment of a stent in the SB results in higher values of WSS distal to the main branch; which may help reduce the development of the restenosis." --
Cfd Analysis Of Coronary Artery Blood Flow From Stenting And Various Levels Of Stenosis
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Author : Luke Matthew Chapdelaine
language : en
Publisher:
Release Date : 2020
Cfd Analysis Of Coronary Artery Blood Flow From Stenting And Various Levels Of Stenosis written by Luke Matthew Chapdelaine and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
Festskrift Til Thorleif Sj Vold P 70 Rsdagen
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Author :
language : en
Publisher:
Release Date : 1984
Festskrift Til Thorleif Sj Vold P 70 Rsdagen written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with categories.