Molecular Approaches To Nephrology
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Molecular Approaches To Nephrology
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Author : F. Paolo Schena
language : en
Publisher:
Release Date : 1993
Molecular Approaches To Nephrology written by F. Paolo Schena and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Hemodialysis categories.
Kidney Research
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Author : Tim D. Hewitson
language : en
Publisher: Springer Nature
Release Date : 2023-07-10
Kidney Research written by Tim D. Hewitson and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-10 with Medical categories.
This third edition provides updated and new chapters on recent innovations in basic renal research. Chapters are divided into three sections covering in vitro, in vivo, and ex vivo models of kidney disease, recent advances in imaging techniques and protocols for performing analytical and functional measurements in the kidney; techniques that are both topical and of widespread relevance to the study of kidney biology and disease. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and methods, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Kidney Research: Experimental Protocols, Third Edition aims to be comprehensive guide for researchers in the field.
Molecular And Genetic Basis Of Renal Disease
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Author : David B. Mount
language : en
Publisher: Elsevier Health Sciences
Release Date : 2008-01-01
Molecular And Genetic Basis Of Renal Disease written by David B. Mount and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-01 with Medical categories.
This companion to Brenner and Rector's The Kidney offers a state-of-the-art summary of the most recent advances in renal genetics. Molecular and Genetic Basis for Renal Disease provides the nephrologist with a comprehensive look at modern investigative tools in nephrology research today, and reviews the molecular pathophysiology of the nephron as well as the most common genetic and acquired renal diseases. A comprehensive clinical review of Medelian renal disease is also be included. Detailed review of the molecular anatomy and pathophysiology of the nephron that provides relevant basic science to consider when diagnosing and managing patients with these disorders.
Renal Development And Disease
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Author : Michael S. Goligorsky
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 2002
Renal Development And Disease written by Michael S. Goligorsky and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Gene expression categories.
Functional genomics is best defined as a tool-kit consisting of a variety of molecular, cellular, and whole-animal approaches, all directed towards elucidation of the role played by genes and their encoded products in maintaining physiological performance or triggering pathologic events. These elements are not controlled by a single gene, but by an ensemble of genes and their products which support the integrated functions of an organ. Understanding the 'wholeness' of these ensembles represents thus a major challenge for functional genomics: It is the spatial and temporal mapping of these processes that constitutes the ultimate goal of biomedical research. This publication is intended to facilitate the recognition of the challenge ahead to provide the tools to address the special requirements of kidney research. Several reviews included describe technical approaches to gene screening, other reviews offer examples of the complexities of gene function in various disease states or their models and an introduction to the use of proteomics to study renal disease. The thoughts and experimental examples gathered in this publication will be a first step in the enormous task ahead towards a better understanding of renal function in health and disease.
Kidney Development
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Author : Odyssé Michos
language : en
Publisher: Humana Press
Release Date : 2012-05-27
Kidney Development written by Odyssé Michos and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-27 with Science categories.
Over the last decade the development of new molecular biology tools, advanced microscopy, live imaging and systems biology approaches have revolutionized our conception of how embryonic development proceeds. One fundamental aspect of development biology is the concept of morphogenesis: understanding how a group of multipotent cells organize and differentiate into a complex organ. In Kidney Development: Methods and Protocols, expert researchers in the field detail different approaches to tackle kidney development. These approaches include culture and live imaging aspects of kidney development, analyzing the 3-dimensional aspects of branching morphogenesis as well as nephrogenesis, manipulation of the gene/protein expression during kidney development as well as in the adult kidney, and how to assess kidney malformation and disease. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Kidney Development: Methods and Protocols seeks to aid scientists in the further study of the process of morphogenesis which is fundamental important not only for studying developmental biology but also for regenerative medicine.
Methods In Kidney Cell Biology Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-08-03
Methods In Kidney Cell Biology Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-03 with Science categories.
Methods in Kidney Cell Biology, Volume 153, represents state-of-the-art techniques in renal research that are ideal for veterans, graduate students, postdoctoral fellows, and clinical scientists and principal investigators. Topics in the new release include Single glomerular proteomics – a novel method in translational glomerular cell biology, Measurement of cytosolic and intraciliary calcium in live cells, Differentiation of human kidney organoids from pluripotent stem cells, Quantifying autophagic flux in kidney tissue using structured illumination microscopy, the Generation of primary cells from ADPKD and normal human kidneys, ADPKD cell proliferation and Cl-dependent fluid secretion, In vitro cyst formation of ADPKD cells, and much more. Written by experts in their field who have perfected the methods they write about Covers a wide range of topics, from state-of-the-art techniques that may require specialized equipment, to tried-and-true classic methods in their most refined form Includes cutting-edge, recently developed methods
Methods In Renal Toxicology
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Author : Rudolfs K. Zalups
language : en
Publisher: CRC Press
Release Date : 1996-03-14
Methods In Renal Toxicology written by Rudolfs K. Zalups and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-03-14 with Medical categories.
The only up-to-date compilation of renal methods available, this book is the definitive resource for any renal researcher eager to stay ahead. Methods in Renal Toxicology presents a vast array of methods for the study of renal cellular and tubular structure, function, and biochemistry under physiological, toxicological, and pathological conditions. It provides detailed descriptions in easy-to-understand language of methods designed to enhance your research efforts. Methods in Renal Toxicology puts you on the cutting edge with valuable chapters detailing molecular methods and transgene and gene targeting - the most recent approaches to the study of renal toxicology. Overall, the book's topics range from non-invasive assessments of renal function in the whole animal and clinical settings to cellular and molecular approaches. Specifically, the book delves into measurements of clearance and urinary markers, histopathology, and methods to assess renal carcinogenesis, mutagenesis, oxidative stress, mitochondria injury, cellular repair, and drug metabolism and transport. A variety of in vitro methods are also described, including the isolated perfused kidney, micropuncture, microperfusion, microdissection, renal slices, isolated perfused tubules, suspensions of tubules and isolated cells, and primary cell cultures and cell lines. Methods in Renal Toxicology is a must-have resource for all renal investigators. Nowhere else can you find concise descriptions of traditional and up-to-the-minute renal toxicology methods in such a practical, well-written single-volume guide.
Methods In Kidney Cell Biology Part B
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-09-01
Methods In Kidney Cell Biology Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-01 with Science categories.
Methods in Kidney Cell Biology, Part B, Volume 154 represents state-of-the-art techniques in renal research that are ideal for veterans, graduate students, postdoctoral fellows, clinical scientists and principal investigators. Topics in the new release include Single glomerular proteomics – a novel method in translational glomerular cell biology, Measurement of cytosolic and intraciliary calcium in live cells, Differentiation of human kidney organoids from pluripotent stem cells, Quantifying autophagic flux in kidney tissue using structured illumination microscopy, the Generation of primary cells from ADPKD and normal human kidneys, ADPKD cell proliferation and Cl-dependent fluid secretion, In vitro cyst formation of ADPKD cells, and much more. Written by experts in their field who have perfected stated methods Covers a wide range of topics, from state-of-the-art techniques that may require specialized equipment, to tried-and-true classic methods in their most refined form Includes cutting-edge, recently developed methods
Diabetic Nephropathy
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Author : Luigi Gnudi
language : en
Publisher: Humana
Release Date : 2019-11-08
Diabetic Nephropathy written by Luigi Gnudi and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-08 with Science categories.
This book provides a toolkit of novel research approaches for investigators to study diabetic nephropathy, including critical experimental models from the fly to the fish, cells in culture, and in vivo mammalian approaches. The collection also explores powerful techniques to image the kidney, such as traditional histological techniques as well as electron, confocal, and two-photon microscopy, pathophysiology of the diabetic kidney, and gene editing and regenerative medicine. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Diabetic Nephropathy: Methods and Protocols seeks to foster new research directions and inspire ideas to enhance our understanding of diabetic nephropathy and to develop treatments for this condition.
Biomarkers Of Kidney Disease
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Author : Charles L. Edelstein
language : en
Publisher: Academic Press
Release Date : 2010-10-27
Biomarkers Of Kidney Disease written by Charles L. Edelstein and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-27 with Medical categories.
A biomarker is a molecule that is measured as a marker of normal biological processes, disease processes or the response to a diagnostic or therapeutic intervention. Kidney diseases like acute kidney injury, chronic kidney disease, diabetic nephropathy, glomerular disease, renal cancer and preeclampsia still have a high morbidity. Measurement of biomarkers in the blood or urine that detect patients at risk of kidney diseases or that detect kidney diseases in the earliest stage may ultimately result in preventative or earlier or more effective treatments for kidney diseases. Biomarkers of Kidney Disease reviews the basic and clinical research on biomarkers of the common kidney diseases including acute kidney injury, chronic kidney disease, renal cancer, diabetic nephropathy, glomerular disease and preeclampsia. The characteristics of an ideal biomarker of kidney diseases and statistical analysis of biomarker studies is detailed. The latest techniques for biomarker detection like metabolomics and proteomics is covered in the book. This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation and preeclampsia. Presents a comprehensive, translational source for all aspects of renal biomarkers in one reference work Experts in renal disease biomarkers (from all areas of academic and medical research) take readers from the bench research (cellular and molecular mechanism) to new therapeutic approaches