Molecular Aspects Of Cancer And Its Therapy
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Molecular Aspects Of Cancer And Its Therapy
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Author : A. Mackiewicz
language : en
Publisher: Birkhäuser
Release Date : 2012-12-06
Molecular Aspects Of Cancer And Its Therapy written by A. Mackiewicz and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
On the basis of the agreement signed between UNESCO and the Government of the Republic of Poland the International Institute for Cell and Molecular Biology of UNESCO was officially inaugurated in October 1995 in Warsaw, Poland, as part of the activity of the Global Network for Molecular and Cell Biology (MCBN) of UNESCO. The occasion was marked by the bringing together in Warsaw of a broad spectrum of cell and molecular biologists from around the world under the auspices of the Global MCBN UNESCO. At the conclusion of that week-long celebration it became clear that Polish cell and molecular biology had come of age in terms of its depth, vigor and impact on the global scene. At the suggestion of Professor Angelo Azzi, chairman of Global MCBN UNESCO, we considered the challenge of compiling a volume in the Molecular and Cell Biology Updates tMCBU) Series that would address the molecular basis of cancer and its therapy, but one that would additionally serve to highlight Polish contributions to this field of research. We accepted the challenge presented to us by Professor Azzi and are grateful to all contributors of the present volume for making this a pleasant and stimulating project. We requested each contributor to present his personal perspective of respective topics. As a consequence, we hope that each contribution has a distinctive individual flavor which reflects the role played by individual research groups in advancing science.
The Molecular Basis Of Cancer
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Author : John Mendelsohn
language : en
Publisher: Saunders
Release Date : 1995
The Molecular Basis Of Cancer written by John Mendelsohn and has been published by Saunders this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with CELICA, TRANSFORMACIJA NEOPLASTIČNA - genetika categories.
This comprehensive, new reference will provide clinicians and other professionals who manage cancer patients, the scientific tools necessary to fully understand the disease and its therapy. The sequence of chapters leads the reader from the basic mechanisms of malignant transformation of cells, to the molecular and biological features of tumour growth and metastasis in the body, then to the molecular abnormalities found in common types of cancer, and finally to the molecular basis for new approaches to cancer therapy. The text reveals the very latest scientific research in cancer treatment and supplies the foundation for new approaches to evaluation and therapy of cancer patients.
The Molecular Basis Of Cancer
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Author : John Mendelsohn
language : en
Publisher: Elsevier Health Sciences
Release Date : 2008-04-01
The Molecular Basis Of Cancer written by John Mendelsohn and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-01 with Medical categories.
Successfully fighting cancer starts with understanding how it begins. This thoroughly revised 3rd Edition explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of cancer. A team of leading experts thoroughly explain the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Incorporating cutting-edge advances and the newest research, the book provides thorough descriptions of everything from molecular abnormalities in common cancers to new approaches for cancer therapy. Features sweeping updates throughout, including molecular targets for the development of anti-cancer drugs, gene therapy, and vaccines...keeping you on the cutting edge of your specialty. Offers a new, more user-friendly full-color format so the information that you need is easier to find. Presents abundant figures-all redrawn in full color-illustrating major concepts for easier comprehension. Features numerous descriptions of the latest clinical strategies-helping you to understand and take advantage of today’s state-of-the-art biotechnology advances.
The Molecular Basis Of Cancer
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Author : John Mendelsohn
language : en
Publisher: Elsevier Health Sciences
Release Date : 2014-02-20
The Molecular Basis Of Cancer written by John Mendelsohn and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-20 with Medical categories.
2015 BMA Medical Book Awards Highly Commended in Oncology Category!The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday clinical application. Effectively determine the course of malignancy and design appropriate treatment protocols by understanding the scientific underpinnings of cancer. Visually grasp and retain difficult concepts easily thanks to a user-friendly format with abundant full-color figures. Find critical information quickly with chapters following a logical sequence that moves from pathogenesis to therapy. Stay current with the latest discoveries in molecular and genomic research. Sweeping revisions throughout include eight brand-new chapters on: Tumor Suppressor Genes; Inflammation and Cancer; Cancer Systems Biology: The Future; Biomarkers Assessing Risk of Cancer; Understanding and Using Information About Cancer Genomes; The Technology of Analyzing Nucleic Acids in Cancer; Molecular Abnormalities in Kidney Cancer; and Molecular Pathology. Access the entire text and illustrations online, fully searchable, at Expert Consult.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
The Molecular Basis Of Cancer
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Author : Peter B. Farmer
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Molecular Basis Of Cancer written by Peter B. Farmer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This book aims to describe the current state of knowledge and possible future developments in a number of major areas of research into the nature, causes and treatment of cancer. The contributing authors have been encouraged to discuss their subjects at the molecular level. It will become apparent to the reader that considerable developments in the understanding of the fundamental nature of cancer, in molecular terms, are constantly being made. This is particularly the case in the area of oncogene research where differences between tumour and normal cells can now be defined in terms of altered expression of DNA sequences. An understanding of the methods available for detecting cancer, of the process of carcinogenesis and of the means available for treating cancer can only be achieved with a precise knowledge of the basic biochemical and molecular processes involved. Since it is all to easy for the research scientist to become totally absorbed within the specialised area of research in which he is involved, the first chapter is an attempt to encourage a broader field of vision by introducing the clinician's view of the cancer problem, which illustrates the broad spectrum of basic problems that need to be solved by the cancer researcher.
The Molecular Basis Of Cancer
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Author : John Mendelsohn
language : en
Publisher: Saunders
Release Date : 2014-02-19
The Molecular Basis Of Cancer written by John Mendelsohn and has been published by Saunders this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-19 with Medical categories.
The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday clinical application. Effectively determine the course of malignancy and design appropriate treatment protocols by understanding the scientific underpinnings of cancer. Visually grasp and retain difficult concepts easily thanks to a user-friendly format with abundant full-color figures. Find critical information quickly with chapters following a logical sequence that moves from pathogenesis to therapy. Stay current with the latest discoveries in molecular and genomic research. Sweeping revisions throughout include eight brand-new chapters on: Tumor Suppressor Genes; Inflammation and Cancer; Cancer Systems Biology: The Future; Biomarkers Assessing Risk of Cancer; Understanding and Using Information About Cancer Genomes; The Technology of Analyzing Nucleic Acids in Cancer; Molecular Abnormalities in Kidney Cancer; and Molecular Pathology. Access the entire text and illustrations online, fully searchable, at Expert Consult.
Molecular Basis Of Breast Cancer
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Author : Jose Russo
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-28
Molecular Basis Of Breast Cancer written by Jose Russo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-28 with Medical categories.
This richly-illustrated atlas-like book provides a foundation for the biological and molecular understanding of how the mammary gland develops and how breast cancer originates. The main goal is to comprehensively review in ten chapters fundamental knowledge in breast cancer. New paradigms are described in which induction of differentiation in the mammary gland can promote prevention and cure of breast cancer. The text is extremely helpful both for clinicians treating patients and researchers looking for new avenues of development.
The Molecular Basis Of Human Cancer
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Author : William B. Coleman
language : en
Publisher: Springer Science & Business Media
Release Date : 2002
The Molecular Basis Of Human Cancer written by William B. Coleman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
The Molecular Basis of Human Cancer covers general molecular concepts in neoplastic transformation, state of the art, detailed descriptions of molecular mechanisms in specific human cancers, and rapidly evolving aspects of cancer research and treatment that are based on molecular mechanisms. Also included is coverage of future issues in human cancer research and treatment, including genetic counseling, molecular diagnosis, molecular pharmacology, and gene therapy. This volume provides an excellent background for the novice on general concepts and established principles governing human neoplastic transformation and tumorigenesis. It also supplies detailed information in organ-specific cancers for the more advanced reader. In addition, the book includes excellent coverage of various topics related to current trends in cancer research and treatment, providing the reader with insight into cutting edge aspects of the cancer field.
Gene Therapy Of Cancer
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Author : Wolfgang Walther
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-01
Gene Therapy Of Cancer written by Wolfgang Walther and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-01 with Medical categories.
Since the discovery of the molecular structure of genes and the unveiling of the molecular basis of numerous human diseases, scientists have been fas- nated with the possibility of treating certain diseases by transducing foreign DNA into the affected cells. Initially, it was proposed that the foreign DNA could either replace defective nonfunctional genes, or code for therapeutic proteins. This concept has evolved into the rapidly growing field of gene therapy. Even though surgery, radiotherapy, and chemotherapy are widely ava- able and routinely used for cancer treatment, these therapies fail to cure approximately 50 percent of cancer patients. Therefore, since it is a disease characterized by aberrant gene expression, cancer has been a target of gene therapy research since the inception of this treatment modality. Numerous cancer gene therapy strategies are currently being investigated, including gene replacement therapy, the regulation of gene expression to modulate immu- logical responses to tumors, the direct killing of tumor cells, and direct int- ference with tumor growth. In this context, gene transfer systems, tumor-specific expression vectors, and novel therapeutic genes have been extensively st- ied. All these strategies aim for the selective destruction of human malignant disease while circumventing the destruction of nonmalignant cells and tissues thereby minimizing toxicity to the patient.