Molecular Clocks And Light Signalling
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Molecular Clocks And Light Signalling
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Author : Derek J. Chadwick
language : en
Publisher: John Wiley & Sons
Release Date : 2004-06-25
Molecular Clocks And Light Signalling written by Derek J. Chadwick and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-06-25 with Science categories.
The ability at the molecular level to keep track of time is a property shared by organisms ranging from the simplest unicells to humans. The primary feature of these biological clocks is their ability to entrain to environmental stimuli. The dominant stimulus comes from environmental light cues, which requires the existence of photopigments sensitive to light. The exact identity of the molecules involved in circadian photoreception has remained elusive. The classical view of the circadian system is of diverse physiological rhythms regulated by a centralized clock structure. This book presents evidence that challenges this view. Experiments in both vertebrate and invertebrate systems demonstrate that the circadian timing system is dispersed throughout the animal and suggest that possibly every cell contains an autonomous clock mechanism. A variety of tissues and cells contain have been shown to maintain an oscillation when placed in vitro and removed from any external cues or signals that originate from the classical clock structures and/or the environment. This book draws together contributions from an international and interdisciplinary group of experts whose work is focused on all aspects of the topic. Coverage includes the mechanisms of light signalling to the vertebrate clock, the connections between central and peripheral clocks, circadian gene expression patterns and output pathways of clock mechanisms.
Visions Of Cardiomyocyte
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Author : Angelos Tsipis
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-01-29
Visions Of Cardiomyocyte written by Angelos Tsipis and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-29 with Medical categories.
In the field of cardiology, some of the most dramatic advances in recent years have come from understanding the molecular and cellular basis of cardiovascular disease. Knowledge of the pathological basis of disease in some cases allows the development of new strategies for prevention and treatment. This book was planned not only to convey new facts on cardiovascular diseases, but also to boost the excitement and challenges of research in the dynamic area of modern molecular and cellular biology of cardiology. The integration of multilevel biological data and the connection with clinical practice reveal the potential of personalized medicine, with future implications for prognosis, diagnosis, and management of cardiovascular diseases.
Translation And Processing Of Light By The Non Image Forming Visual System Context Mechanisms And Applications
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Author : Fabian-Xosé Fernandez
language : en
Publisher: Frontiers Media SA
Release Date : 2021-10-18
Translation And Processing Of Light By The Non Image Forming Visual System Context Mechanisms And Applications written by Fabian-Xosé Fernandez and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-18 with Medical categories.
The Biology Of Sole
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Author : José A. Munoz-Cueto
language : en
Publisher: CRC Press
Release Date : 2019-05-13
The Biology Of Sole written by José A. Munoz-Cueto and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-13 with Nature categories.
This book reviews up-to-date knowledge on the biology of sole (Solea senegalensis and S. solea). These flatfish species are increasingly important in Europe both from the ecological and production point of view. This book is divided into two sections: A. general fisheries, aquaculture and engineering overviews; B. physiological, developmental, rhythmic, welfare and genetic aspects which will be of immense interest for the aquaculture industry. Experts, from both academia and research institutes, provide their expertise on sole biology.
Development Of Circadian Clock Functions Volume Ii
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Author : Daisuke Ono
language : en
Publisher: Frontiers Media SA
Release Date : 2024-07-31
Development Of Circadian Clock Functions Volume Ii written by Daisuke Ono and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-31 with Science categories.
The temporal order of physiological functions such as sleep/wakefulness is regulated by the circadian clock. This intrinsic clock starts ticking in the embryo and matures during development, with attenuation of the clock function in the elderly, illustrated by attenuation of synchrony, entrainment, and outputs of cellular circadian rhythms in the SCN. This age-related diminution can contribute to the emergence of diseases, such as sleep disorders, infertility, diabetes, mental disorders etc. Over the course of our lives, a variety of internal and external factors are under the influence of the circadian clock. This inherent developmental plasticity of the circadian system is critical for the establishment of normal bodily functions to adapt to the changing environment on earth. In mammals, the central circadian clock is located in the suprachiasmatic nucleus (SCN) of the hypothalamus. Circadian rhythms in the SCN are observed during the embryonic period, and input and output pathways from the SCN are formed after birth. During postnatal development, functions of neurotransmitters in the SCN are changed, which have an influence on special temporal patterns of circadian rhythms in the SCN and outputs signals to the outside of the SCN. During postnatal development properties of circadian rhythms in the SCN and its inputs and outputs can be modulated by environmental light conditions. Recent optical manipulation and imaging techniques have revealed that cell type specific functions for circadian rhythms. However, it remains unclear which cell types or networks in the brain are modulated during postnatal development, and how these cells regulate circadian rhythms depending on postnatal period.
The Retina And Its Disorders
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Author : Joseph Besharse
language : en
Publisher: Academic Press
Release Date : 2011-04-19
The Retina And Its Disorders written by Joseph Besharse and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-19 with Medical categories.
This selection of articles from the Encyclopedia of the Eye covering retina, optics/optic nerve and comparative topics constitutes the first reference for scientists, post docs, and graduate students with an interest beyond standard textbook materials. It covers the full spectrum of research on the retina - from the basic biochemistry of how nerve cells are created to information on neurotransmitters, comparisons of the structure and neuroscience of peripheral vision systems in different species, and all the way through to injury repair and other clinical applications. - The first single volume to integrate comparative studies into a comprehensive resource on the neuroscience of the retina - Chapters are carefully selected from the Encyclopedia of the Eye by one of the world's leading vision researchers - The best researchers in the field provide their conclusions in the context of the latest experimental results
Encyclopedia Of The Eye
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Author : Joseph Besharse
language : en
Publisher: Academic Press
Release Date : 2010-05-27
Encyclopedia Of The Eye written by Joseph Besharse and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-27 with Science categories.
As the first comprehensive reference for the eye, its support structures, diseases, and treatments, Encyclopedia of the Eye is an important resource for all visual scientists, ophthalmologists, and optometrists, as well as researchers in immunology, infectious disease, cell biology, neurobiology and related disciplines. This four-volume reference is unique in its coverage of information on all tissues important for vision, including the retina, cornea and lens. It also covers the physiological and pathophysiologic processes that affect all eye tissues. This Encyclopedia is invaluable for graduate students and postdoctoral fellows who are seeking an introduction to an area of eye research. Each chapter explains the basic concepts and provides references to relevant chapters within the Encyclopedia and more detailed articles across the wider research literature. The Encyclopedia is also particularly useful for visual scientists and practitioners who are researching a new area, seeking deeper understanding of important research articles in fields adjacent to their own, or reviewing a grant outside their immediate area of expertise. Written by experts at a level that permits students to grasp key elements of a specific subject Provides an entryway into the major features of current eye research No other source puts this much information, so well-indexed and with so many helpful full color figures and graphics, in the hands of the ophthalmic scientist
The Clock Mirage
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Author : Joseph Mazur
language : en
Publisher: Yale University Press
Release Date : 2020-04-14
The Clock Mirage written by Joseph Mazur and has been published by Yale University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-14 with Science categories.
A tour of clocks throughout the centuries—from the sandglass to the telomere—to reveal the physical, biological, and social nature of time What is time? This question has fascinated philosophers, mathematicians, and scientists for thousands of years. Why does time seem to speed up with age? What is its connection with memory, anticipation, and sleep cycles? Award-winning author and mathematician Joseph Mazur provides an engaging exploration of how the understanding of time has evolved throughout human history and offers a compelling new vision, submitting that time lives within us. Our cells, he notes, have a temporal awareness, guided by environmental cues in sync with patterns of social interaction. Readers learn that, as a consequence of time’s personal nature, a forty-eight-hour journey on the Space Shuttle can feel shorter than a six-hour trip on the Soyuz capsule, that the Amondawa of the Amazon do not have ages, and that time speeds up with fever and slows down when we feel in danger. With a narrative punctuated by personal stories of time’s effects on truck drivers, Olympic racers, prisoners, and clockmakers, Mazur’s journey is filled with fascinating insights into how our technologies, our bodies, and our attitudes can change our perceptions. Ultimately, time reveals itself as something that rides on the rhythms of our minds. The Clock Mirage presents an innovative perspective that will force us to rethink our relationship with time, and how best to use it.
Signaling Pathways In Liver Diseases
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Author : Jean-Francois Dufour
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-08-15
Signaling Pathways In Liver Diseases written by Jean-Francois Dufour and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-08-15 with Medical categories.
This book serves as a source of information to facilitate the reading of the literature and the planning of trials. Supplies in one place all the information on this active and complex research topic and may stimulate more research that can lead to more exchanges between the laboratory, the clinical ward and the operating room. Fills the need of surgeons to understand the molecular mechanisms in hepatology. Provides a quick and comprehensive overview.
Hypothalamic Integration Of Energy Metabolism
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Author : A. Kalsbeek
language : en
Publisher: Elsevier
Release Date : 2006-08-21
Hypothalamic Integration Of Energy Metabolism written by A. Kalsbeek and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-08-21 with Science categories.
The prevalence of obesity in developed countries is fast becoming a health issue on par with infectious diseases and malnutrition. Research in this area has grown substantially and includes the neurochemical pathways of the hypothalamus and its role in regulating energy expenditures in the body. This volume in the Progress in Brain Research series examines the emerging role of the hypothalamus as a crucial link between the sensing of nutrients and the control of insulin sensitivity, glucose uptake, and glucose production, the integrative role of the hypothalamus in thyroid and bone metabolism, the interaction between circadian information and energy metabolism, and the important interplay between the immune system and energy metabolism.· All contributors are recognized experts in their respective specialities· Provides expanded coverage of hypothalamic mechanisms involved in energy metabolism· Includes many outstanding full-colour illustrations· Contains special sections on circadian rhythms, immune system, thyroid and bone metabolism