Molecular Considerations And Evolving Surgical Management Issues In The Treatment Of Patients With A Brain Tumor
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Molecular Considerations And Evolving Surgical Management Issues In The Treatment Of Patients With A Brain Tumor
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Author : Terry Lichtor
language : en
Publisher: BoD – Books on Demand
Release Date : 2015-03-25
Molecular Considerations And Evolving Surgical Management Issues In The Treatment Of Patients With A Brain Tumor written by Terry Lichtor and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-25 with Medical categories.
A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years. In particular, recent new avenues regarding the role of microRNAs along with further understanding of the importance of angiogenesis, immunotherapy and explanations for the resistance of the tumors to radiation therapy have been developed. A discussion of certain surgical management issues including improvements in imaging along with issues concerning tumor induced epilepsy is included. It is hopeful that this new information will lead to efficacious treatment strategies for these tumors which remain a challenge. In this book, a review of the latest information on these topics along with a variety of new therapeutic treatment strategies with an emphasis on molecular targeted therapies is provided.
Resistance To Targeted Therapies Against Adult Brain Cancers
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Author : Amanda Tivnan
language : en
Publisher: Springer
Release Date : 2016-11-26
Resistance To Targeted Therapies Against Adult Brain Cancers written by Amanda Tivnan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-26 with Medical categories.
This volume will bring together a review of research being carried out by international experts in this field, detailing treatment and research approaches in several forms of malignant brain tumors. These include glioblastoma (GBM), a highly aggressive and fatal form of astrocytoma which accounts for 80% of newly diagnosed brain tumor patients per year, and meningioma, of which 10% are malignant and extremely resistant to targeted therapies. The volume will also include a discussion of methods to overcome blood-brain barrier exclusion for more efficient targeted drug delivery in all forms of brain cancer treatment. The volume will include information on the repurposing of drugs in an attempt to circumvent drug resistance, use of small molecule inhibitors in GBM treatment, mechanisms of secondary brain metastasis, drug resistance, and state-of-the-art imaging of targeted therapies.
Cannabis
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Author : Ernest Small
language : en
Publisher: CRC Press
Release Date : 2016-10-14
Cannabis written by Ernest Small and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-14 with Science categories.
Cannabis sativa is best known as the source of marijuana, the world’s most widely consumed illicit recreational drug. However, the plant is also extremely useful as a source of stem fiber, edible seed oil, and medicinal compounds, all of which are undergoing extremely promising research, technological applications, and business investment. Indeed, despite its capacity for harm as a recreational drug, cannabis has phenomenal potential for providing new products to benefit society and for generating extensive employment and huge profits. Misguided policies, until recently, have prevented legitimate research on the beneficial properties of cannabis, but there is now an explosion of societal, scientific, and political support to reappraise and remove some of the barriers to usage. Unfortunately, there is also a corresponding dearth of objective analysis. Towards redressing the limitation of information, Cannabis: A Complete Guide is a comprehensive reference summarizing botanical, business, chemical, ecological, genetic, historical, horticultural, legal, and medical considerations that are critical for the wise advancement and management of cannabis in its various forms. This book documents both the risks and benefits of what is indisputably one of the world’s most important species. The conflicting claims for medicinal virtues and toxicological vices are examined, based mainly on the most recent authoritative scientific reviews. The attempt is made consistently to reflect majority scientific opinion, although many aspects of cannabis are controversial. Aside from the relevance to specialists, the general public should find the presentation attractive because of the huge interest today in marijuana. Unfortunately, society has become so specialized and compartmentalized that most people have limited appreciation of the importance of science to their lives, except when a topic like marijuana becomes sensationalized. This review of cannabis can serve as a vehicle for public education in the realm of science and technology. Indeed, towards the goal of disseminating the important information in this book to a wide audience, the presentation is user-friendly, concise, and well-illustrated in the hope that non-specialists will find the topics both informative and entertaining.
Computational Diffusion Mri
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Author : Elisenda Bonet-Carne
language : en
Publisher: Springer Nature
Release Date : 2020-11-06
Computational Diffusion Mri written by Elisenda Bonet-Carne and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-06 with Mathematics categories.
This volume gathers papers presented at the Workshop on Computational Diffusion MRI (CDMRI 2019), held under the auspices of the International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), which took place in Shenzhen, China on October 17, 2019. This book presents the latest advances in the rapidly expanding field of diffusion MRI. It shares new perspectives on the latest research challenges for those currently working in the field, but also offers a valuable starting point for anyone interested in learning about computational techniques in diffusion MRI. The book includes rigorous mathematical derivations, a wealth of rich, full-colour visualisations and extensive clinically relevant results. As such, it will be of interest to researchers and practitioners in the fields of computer science, MRI physics and applied mathematics. Readers will find contributions covering a broad range of topics, from the mathematical foundations of the diffusion process and signal generation, to new computational methods and estimation techniques for the in vivo recovery of microstructural and connectivity features, as well as diffusion-relaxometry and frontline applications in research and clinical practice. This edition includes invited works from high-profile researchers with a specific focus on three new and important topics that are gaining momentum within the diffusion MRI community, including diffusion MRI signal acquisition and processing strategies, machine learning for diffusion MRI, and diffusion MRI outside the brain and clinical applications.
Glioblastoma State Of The Art And Future Perspectives
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Author : Ghazaleh Tabatabai
language : en
Publisher: MDPI
Release Date : 2020-12-10
Glioblastoma State Of The Art And Future Perspectives written by Ghazaleh Tabatabai and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-10 with Science categories.
Glioblastoma is an aggressive incurable primary tumor of the central nervous system. Median overall survival is in the range of 1.5 years even in selected clinical trials populations. Many features contribute to this therapeutic challenge including high intratumoral and intertumoral heterogeneity, resistance to therapy, migration and invasion, immunosuppression. With the access of novel highthroughput technologies, significant progress has been made to understand molecular and immunological signatures underlying the pathology of glioblastoma. Clinical trial designs have shifted from investigating broad “one-for-all” treatment approaches to precision oncology designs. The collection of contributions in this book aim at providing researchers and clinicians an update on different aspects of glioblastoma, i.e. progress in basic, preclinical and clinical research.
Cardiorespiratory Fitness In Cardiometabolic Diseases
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Author : Peter Kokkinos
language : en
Publisher: Springer
Release Date : 2019-03-18
Cardiorespiratory Fitness In Cardiometabolic Diseases written by Peter Kokkinos and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-18 with Medical categories.
This book examines the links between physical activity (PA), cardiorespiratory fitness (CRF), and cardiovascular and metabolic diseases. It presents an overview of the role of PA and CRF in the prevention and management of risk factors associated with cardiometabolic diseases such as hypertension, peripheral vascular disease, stroke, type 2 diabetes, metabolic syndrome, dyslipidemia, obesity, and atherosclerosis. In addition, it explores how these risks vary with different populations such as the elderly and people of various racial backgrounds. The book also highlights risks associated with exercise and presents a prescription for appropriate and efficacious exercise to minimize risk and maximize health benefits for the heart. Cardiorespiratory Fitness in Prevention and Management of Cardiometabolic Disease is an essential resource for physicians, exercise physiologists, medical students, residents, fellows, nurses, and researchers in cardiology, cardiorespiratory fitness, exercise science, health promotion and disease prevention, public health, and epidemiology.
Brain Tumors
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Author : Amit Agrawal
language : en
Publisher: BoD – Books on Demand
Release Date : 2022-04-20
Brain Tumors written by Amit Agrawal and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-20 with Medical categories.
Brain tumors comprise a spectrum of histological patterns. Their presentation and management depend on their location, size, and grade of lesions. This book is a collection of high-quality research work from global experts on brain tumors, including meningiomas, and their treatment.
Epilepsy And Brain Tumors
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Author : Herbert B. Newton
language : en
Publisher: Elsevier
Release Date : 2015-03-06
Epilepsy And Brain Tumors written by Herbert B. Newton and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-06 with Medical categories.
Patients with brain tumor-related epilepsy (BTRE) suffer from two serious pathologies simultaneously – a brain tumor and a secondary form of epilepsy. Although there has been remarkable progress in BTRE research in recent years, it remains an on-going challenge for clinicians and continues to stimulate much debate in the scientific community. This volume is the first to be completely dedicated to BTRE, and in doing so it explores issues faced by the health care team as well as some of the novel and promising directions that future research may take. Epilepsy and Brain Tumors is not only a complete reference on BTRE but also a practical guide based on clinical experiences, with a comprehensive collection of presentations from international experts who share some of the latest discoveries and their approaches to tackling a wide range of difficult and complex issues. Includes coverage of epidemiology, pathology and treatment of both primary and metastatic brain tumors Offers additional insight into supportive care, incidence in children, focal epileptogenesis, clinical evaluation, antiepileptic drugs, surgical treatment, cognitive rehabilitation, and more Chapters authored and edited by leaders in the field around the globe – the broadest, most expert coverage available
Adult Craniopharyngiomas
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Author : Emmanuel Jouanneau
language : en
Publisher: Springer Nature
Release Date : 2020-04-09
Adult Craniopharyngiomas written by Emmanuel Jouanneau and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-09 with Medical categories.
This volume focuses on adult craniopharyngiomas, offering various perspectives. The first part of the book provides an up-to-date overview of the pathogenesis and management of adult craniopharyngiomas, helping readers understand the pathogenesis and molecular pathways. It highlights the importance of animal models for addressing molecular keys and for developing targeted therapies. The second part deals with clinical management, detailing the latest results in the era of endoscopic surgery, including the major contribution of the extended nasal endoscopic approaches for suprasellar and retrochiasmatic tumors. The book also discusses the key aspects of these tumors and how to manage them. The last part of the book addresses the future therapies and recurrences after surgery and radiotherapy. This volume is of interest to neurosurgeons, endocrinologists, paediatricians, radiologists and oncologists.
Brain Tumor Imaging
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Author : Elke Hattingen
language : en
Publisher: Springer
Release Date : 2015-09-02
Brain Tumor Imaging written by Elke Hattingen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-02 with Medical categories.
This book describes the basics, the challenges and the limitations of state of the art brain tumor imaging and examines in detail its impact on diagnosis and treatment monitoring. It opens with an introduction to the clinically relevant physical principles of brain imaging. Since MR methodology plays a crucial role in brain imaging, the fundamental aspects of MR spectroscopy, MR perfusion and diffusion-weighted MR methods are described, focusing on the specific demands of brain tumor imaging. The potential and the limits of new imaging methodology are carefully addressed and compared to conventional MR imaging. In the main part of the book, the most important imaging criteria for the differential diagnosis of solid and necrotic brain tumors are delineated and illustrated in examples. A closing section is devoted to the use of MR methods for the monitoring of brain tumor therapy. The book is intended for radiologists, neurologists, neurosurgeons, oncologists and other scientists in the biomedical field with an interest in neuro-oncology.