Molecular Genetic Analysis Of Populations
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Molecular Genetic Analysis Of Populations
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Author : A. R. Hoelzel
language : en
Publisher: Oxford University Press
Release Date : 1998-03-19
Molecular Genetic Analysis Of Populations written by A. R. Hoelzel and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-03-19 with Science categories.
Methods enabling the direct study of genetic variation in natural populations have improved considerably. The new edition explores these updated techniques in DNA analysis and provides a revised and refined laboratory guide to investigating variation in DNA molecules.
Mathematical And Statistical Methods For Genetic Analysis
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Author : Kenneth Lange
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Mathematical And Statistical Methods For Genetic Analysis written by Kenneth Lange and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
During the past decade, geneticists have cloned scores of Mendelian disease genes and constructed a rough draft of the entire human genome. The unprecedented insights into human disease and evolution offered by mapping, cloning, and sequencing will transform medicine and agriculture. This revolution depends vitally on the contributions of applied mathematicians, statisticians, and computer scientists. Mathematical and Statistical Methods for Genetic Analysis is written to equip students in the mathematical sciences to understand and model the epidemiological and experimental data encountered in genetics research. Mathematical, statistical, and computational principles relevant to this task are developed hand in hand with applications to population genetics, gene mapping, risk prediction, testing of epidemiological hypotheses, molecular evolution, and DNA sequence analysis. Many specialized topics are covered that are currently accessible only in journal articles. This second edition expands the original edition by over 100 pages and includes new material on DNA sequence analysis, diffusion processes, binding domain identification, Bayesian estimation of haplotype frequencies, case-control association studies, the gamete competition model, QTL mapping and factor analysis, the Lander-Green-Kruglyak algorithm of pedigree analysis, and codon and rate variation models in molecular phylogeny. Sprinkled throughout the chapters are many new problems.
Molecular Genetic Analysis Of Populations
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Author : A. Rus Hoelzel
language : en
Publisher:
Release Date : 1992
Molecular Genetic Analysis Of Populations written by A. Rus Hoelzel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Science categories.
A Primer Of Molecular Population Genetics
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Author : Asher D. Cutter
language : en
Publisher:
Release Date : 2019
A Primer Of Molecular Population Genetics written by Asher D. Cutter and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Science categories.
What are the genomic signatures of adaptations in DNA? How often does natural selection dictate changes to DNA? How does the ebb and flow in the abundance of individuals over time get marked onto chromosomes to record genetic history? Molecular population genetics seeks to answer such questions by explaining genetic variation and molecular evolution from micro-evolutionary principles. It provides a way to learn about how evolution works and how it shapes species by incorporating molecular details of DNA as the heritable material. It enables us to understand the logic of how mutations originate, change in abundance in populations, and become fixed as DNA sequence divergence between species. With the revolutionary advances in genomic data acquisition, understanding molecular population genetics is now a fundamental requirement for today's life scientists. These concepts apply in analysis of personal genomics, genome-wide association studies, landscape and conservation genetics, forensics, molecular anthropology, and selection scans. This book introduces, in an accessible way, the bare essentials of the theory and practice of molecular population genetics.
Molecular Genetic Approaches In Conservation
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Author : Thomas B. Smith
language : en
Publisher: Oxford University Press
Release Date : 1996-10-24
Molecular Genetic Approaches In Conservation written by Thomas B. Smith and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-10-24 with Science categories.
Molecular techniques are proving invaluable in determining the phylogenetic status of potentially endangered species, for investigating mechanisms of speciation, and for measuring the genetic structure of populations. It is increasingly important for ecologists and evolutionary and conservation biologists to understand and use such molecular techniques, but most workers in these areas have not been trained in molecular biology. This book lays out the principles and basic techniques for the molecular tools appropriate for addressing issues in conservation, and it presents case studies showing how these tools have been used successfully in conservation biology. Examples include the genetic analysis of population structure, various uses of DNA in conservation genetics, and estimation of migration parameters from genetic data. Wildlife managers, as well as researchers in these areas, will find this a valuable book.
Molecular Genetic And Statistical Techniques For Behavioral And Neural Research
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Author : Robert T. Gerlai
language : en
Publisher: Academic Press
Release Date : 2018-04-24
Molecular Genetic And Statistical Techniques For Behavioral And Neural Research written by Robert T. Gerlai and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-24 with Science categories.
Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. - Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials - Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior - Written and edited by leading international experts
An Introduction To Statistical Genetic Data Analysis
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Author : Melinda C. Mills
language : en
Publisher: MIT Press
Release Date : 2020-02-18
An Introduction To Statistical Genetic Data Analysis written by Melinda C. Mills and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-18 with Science categories.
A comprehensive introduction to modern applied statistical genetic data analysis, accessible to those without a background in molecular biology or genetics. Human genetic research is now relevant beyond biology, epidemiology, and the medical sciences, with applications in such fields as psychology, psychiatry, statistics, demography, sociology, and economics. With advances in computing power, the availability of data, and new techniques, it is now possible to integrate large-scale molecular genetic information into research across a broad range of topics. This book offers the first comprehensive introduction to modern applied statistical genetic data analysis that covers theory, data preparation, and analysis of molecular genetic data, with hands-on computer exercises. It is accessible to students and researchers in any empirically oriented medical, biological, or social science discipline; a background in molecular biology or genetics is not required. The book first provides foundations for statistical genetic data analysis, including a survey of fundamental concepts, primers on statistics and human evolution, and an introduction to polygenic scores. It then covers the practicalities of working with genetic data, discussing such topics as analytical challenges and data management. Finally, the book presents applications and advanced topics, including polygenic score and gene-environment interaction applications, Mendelian Randomization and instrumental variables, and ethical issues. The software and data used in the book are freely available and can be found on the book's website.
Fungal Genetics
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Author : Cees Bos
language : en
Publisher: CRC Press
Release Date : 1996-03-12
Fungal Genetics written by Cees Bos and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-03-12 with Science categories.
This is a concise guide to the combined use of classical and molecular methods for the genetic analysis and breeding of fungi. It presents basic concepts and experimental designs, and demonstrates the power of fungal genetics for applied research in biotechnology and phytopathology. Case studies of Saccharomyces cerevisiae, Candida albicans, Aspergillus niger, Neurospora crassa, Podospora anserina, Phytophthora infestans and others are included.
Dna Fingerprinting Approaches And Applications
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Author : Terry Burke
language : en
Publisher: Birkhäuser
Release Date : 1991-08
Dna Fingerprinting Approaches And Applications written by Terry Burke and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-08 with Juvenile Nonfiction categories.
Although DNA fingerprinting is a very young branch of molecular genetics, being barely six years old, its recent impact on science, law and politics has been dramatic. The application of DNA finger printing to forensic and legal medicine has guaranteed a high public profile for this technology, and indeed, scarcely a week goes by with out the press reporting yet another crime successfully solved by molec ular genetics. Less spectacularly, but equally importantly, DNA typing methods are steadily diffusing into an ever wider set of applications and research fields, ranging from medicine through to conservation biology. To date, two DNA fingerprinting workshops have been held in the UK, one in 1988 organised by Terry Burke at the University of Leicester, and the second in 1989 at the University of Nottingham, co-ordinated by David Parkin. In parallel with these workshops, which have provided an important focus for researchers, Bill Amos and Josephine Pemberton in Cambridge have established an informal newsletter "Fingerprint News" which is playing a major role as a forum for DNA fingerprinters. By 1989, it was clear that the field had broadened sufficiently to warrant a full international meeting. As a result, Gaudenz Dolf took on the task of organising the first, of what I hope will be many, International Symposium of DNA Fingerprinting held at Bern during Ist-3rd October 1990. The success of the meeting can be judged from the remarkable attendance, with 270 delegates from no less than 30 countries.
Environmental Epigenetics
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Author : L. Joseph Su
language : en
Publisher: Springer
Release Date : 2015-05-18
Environmental Epigenetics written by L. Joseph Su and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-18 with Medical categories.
This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.