Molecular Imaging In Neuroscience
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Molecular Imaging In Neuroscience
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Author : Najam Arfeen Sharif
language : en
Publisher: IRL Press
Release Date : 1993
Molecular Imaging In Neuroscience written by Najam Arfeen Sharif and has been published by IRL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Autoradiography categories.
This book reflects the recent dramatic advances in the use of modern imaging techniques to visualize and quantify the various components of cell structure and cell functional activity in the nervous system. Readers will find detailed protocols for imaging neurotransmitter and receptor mRNAs using radioactive and non-radioactive in situ hybridization technology. Methods for visualizing transmitter and drug receptors using quantitative autoradiography, sequence-specific antibodies, and immunocytochemistry are also clearly described. Plus, the book covers the imaging of biological activity in living cells, including methods of monitoring intracellular pH and calcium mobilization using selective ion-sensitive dyes in conjunction with flow cytometry and video microscopy. This is an essential guide for researchers wanting to exploit these powerful new techniques for their studies in neuropharmacology, neuroanatomy, neurogenetics, neuropathology, and pharmaceutical research. receptors, and receptor function in the nervous system. They represent the state of the art for studying brain function and dysfunction in the laboratory. It will be of major interest to neuroscientists and pharmacologists.
Molecular Imaging In The Clinical Neurosciences
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Author : Gerhard Gründer
language : en
Publisher: Humana Press
Release Date : 2012-07-24
Molecular Imaging In The Clinical Neurosciences written by Gerhard Gründer and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-24 with Medical categories.
While researchers with Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) essentially addressed questions from the whole spectrum of cardiology, oncology, and the neurosciences, it was most notably the latter that provided completely new insights into physiological and disturbed human brain function. In Molecular Imaging in the Clinical Neurosciences, experts in the field provide the reader with up-to-date information on the basic principles of molecular imaging and its major applications in the clinical neurosciences. Beginning with a section offering a comprehensive review of the methodological foundations from physics, chemistry, and mathematics including mathematical modeling, essential for meaningful data analysis, this detailed volume then continues with sections on the major biological principles and neurochemical targets relevant in current neuroimaging research and the major clinical applications from the fields of psychiatry and neurology. Written for the popular Neuromethods series, this work contains the kind of key description and implementation advice that guarantees successful results. Authoritative and cutting-edge, Molecular Imaging in the Clinical Neurosciences serves as a helpful source of knowledge for both basic and clinical scientists from psychology, psychiatry, neurology, nuclear medicine, nuclear chemistry, and the associated disciplines, all of which makes molecular imaging such a rewarding, interdisciplinary field of work.
Molecular Imaging Of The Brain
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Author : M. M. Kaila
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-09-20
Molecular Imaging Of The Brain written by M. M. Kaila and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-20 with Technology & Engineering categories.
This book examines multi-quantum magnetic resonance imaging methods and the diagnostics of brain disorders. It consists of two Parts. The part I is initially devoted towards the basic concepts of the conventional single quantum MRI techniques. It is supplemented by the basic knowledge required to understand multi-quantum MRI. Practical illustrations are included both on recent developments in conventional MRI and the MQ-MRI. This is to illustrate the connection between theoretical concepts and their scope in the clinical applications. The Part II initially sets out the basic details about quadrupole charge distribution present in certain nuclei and their importance about the functions they perform in our brain. Some simplified final mathematical expressions are included to illustrate facts about the basic concepts of the quantum level interactions between magnetic dipole and the electric quadrupole behavior of useful nuclei present in the brain. Selected practical illustrations, from research and clinical practices are included to illustrate the newly emerging ideas and techniques. The reader should note that the two parts of the book are written with no interdependence. One can read them quite independently.
Brain Imaging In Behavioral Neuroscience
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Author : Cameron S. Carter
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-11-04
Brain Imaging In Behavioral Neuroscience written by Cameron S. Carter and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-04 with Medical categories.
This volume highlights the remarkable new developments in brain imaging, including those that apply magnetic resonance imaging (MRI) and Positron Emission Tomography (PET), that allow us to non invasively study the living human brain in health and in disease. These technological advances have allowed us to obtain new and powerful insights into the structure and function of the healthy brain as it develops across the life cycle, as well as the molecular make up of brain systems and circuits as they develop and change with age. New brain imaging technologies have also given us new insights into the causes of many common brain disorders, including ADHD, schizophrenia, depression and Alzheimer’s disease, which collectively affect a large segment of the population. These new insights have major implications for understanding and treating these brain disorders, and are providing clinicians with the first ever set of biomarkers that can be used to guide diagnosis and monitor treatment effects. The advances in brain imaging over the last 20 years, summarized in this volume, represent a major advance in modern biomedical sciences.
Imaging In Cns Drug Discovery And Development
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Author : David Borsook
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-03-10
Imaging In Cns Drug Discovery And Development written by David Borsook and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-10 with Medical categories.
Drug development today needs to balance agility, speed, and risk in defining probability of success for molecules, mechanisms, and therapeutic concepts. New techniques such as fMRI promise to be part of a sequence that could transform drug development. Although numerous review articles exist that discuss the use of imaging in drug development, no one source is available that combines the various techniques and includes a discussion of disease mapping. Imaging in CNS Drug Discovery and Development, Implications for Disease and Therapy will serve to distill the most salient developments in the use of imaging in drug development and disease mapping. It will launch evolving concepts that integrate new imaging technologies and paradigms with molecular medicine and molecular profiling ("monics") as well as consider the ethical issues that arise as a result of disease or state diagnosis and the use of imaging in the public eye.
Imaging In Movement Disorders Imaging In Atypical Parkinsonism And Familial Movement Disorders
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Author :
language : en
Publisher: Academic Press
Release Date : 2018-11-05
Imaging In Movement Disorders Imaging In Atypical Parkinsonism And Familial Movement Disorders written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-05 with Medical categories.
Imaging in Movement Disorders: Imaging in Atypical Parkinsonism and Familial Movement Disorders, Volume 142, addresses the use of imaging modalities across the spectrum of movement disorders and dementias. Over the last decades, advances in neuroimaging tools have played a pivotal role in expanding our understanding of disease aetiology and pathophysiology, identifying biomarkers to monitor disease progression, aiding differential diagnosis and in the identification of novel targets for therapeutic intervention. This updated volume covers PET Molecular Imaging in Atypical Parkinsonism, SPECT Molecular Imaging in Atypical Parkinsonism, Structural MRI in Atypical Parkinsonism, Functional MRI in Atypical Parkinsonism, and more. Offers a complete review of the applications of neuroimaging tools in Atypical Parkinsonism, familial Parkinson’s disease and Huntington’s disease Discusses the role of neuroimaging modalities, including SPECT, PET, and structural and functional MRI Includes sections on potential clinical applications and future directions
Brain Imaging Using Pet
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Author : Michio Senda
language : en
Publisher: Gulf Professional Publishing
Release Date : 2002
Brain Imaging Using Pet written by Michio Senda and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
Discusses PET technique and instrumentation, as well as developments in a range of fields such as kinetics, enzyme/neurotransmitter transport, language acquisition, and neuropathology. This title offers an analysis of brain imaging and techniques, from the foundations to the practical applications of the modern techniques used in PET.
Make Life Visible
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Author : Yoshiaki Toyama
language : en
Publisher: Springer Nature
Release Date : 2019-10-02
Make Life Visible written by Yoshiaki Toyama and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-02 with Medical categories.
This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology inthe broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license.
Imaging In Movement Disorders Imaging Applications In Non Parkinsonian And Other Movement Disorders
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Author : Marios Politis
language : en
Publisher: Academic Press
Release Date : 2018-11-21
Imaging In Movement Disorders Imaging Applications In Non Parkinsonian And Other Movement Disorders written by Marios Politis and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-21 with Medical categories.
Imaging in Movement Disorders: Imaging in Other Movement Disorders and Dementia, Volume 143 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including idiopathic and sporadic forms of Parkinson’s disease, Huntington’s disease, Atypical Parkinsonism, Dystonia, Essential Tremor, and more. Specific chapters cover Neuroimaging Applications in Dystonia, Neuroimaging Applications in Essential Tremor, Neuroimaging applications in Restless Leg Syndrome, Neuroimaging Application in Tourette's Syndrome and TIC Disorders, Neuroimaging Applications in Functional Movement Disorders, and Neuroimaging Applications in Cerebellar Disorders. Addition sections cover Molecular Imaging of Parkinson's Disease Cognitive Impairment, Structural MRI in Parkinson's Disease Cognitive Impairment, Functional MRI in Parkinson's Disease Cognitive Impairment, Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional MRI of Dementia with Lewy Bodies, Transcranial Sonography in Movement Disorders, Imaging transplantation in Movement Disorders, Hybrid PET-MRI Applications in Movement Disorders, amongst other topics. Offers a complete review of the application of neuroimaging tools in Dystonia, Essential Tremor, Restless Leg Syndrome, Tourette’s syndrome, and Tic and Movement Disorders Covers the role of neuroimaging research in movement disorder dementias Presents the importance of imaging techniques as biomarkers of disease progression and treatment response in therapeutic trials
Brain Imaging
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Author : Henry N. Wagner
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-01-29
Brain Imaging written by Henry N. Wagner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-29 with Medical categories.
This book describes what molecular imaging is, how it developed, what are its basic principles, and what it has told us and can tell us about the chemistry of the human brain. Everyone today is conscious of the fact that there is chemistry going on in the brain, and that it is affected by widely used pharmaceuticals and illicit drugs. This book will elucidate these topics in an interesting, historical and philosophical way. The book is a valuable reference resource for all those in nuclear medicine and radiology as well the educated general public.