Molecular Mechanisms Of Signalling And Membrane Transport
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Molecular Mechanisms Of Signalling And Membrane Transport
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Author : Karel W.A. Wirtz
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Molecular Mechanisms Of Signalling And Membrane Transport written by Karel W.A. Wirtz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
Proceedings of the NATO Study Institute on Molecular Mechanisms of Signalling and Targeting, held on the Island of Spetsai, Greece, August 18-30, 1996
Cellular Signal Processing
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Author : Friedrich Marks
language : en
Publisher: Garland Science
Release Date : 2017-05-17
Cellular Signal Processing written by Friedrich Marks and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-17 with Medical categories.
Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.
Molecular Mechanisms Controlling Transmembrane Transport
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Author : Eckhard Boles
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-06-16
Molecular Mechanisms Controlling Transmembrane Transport written by Eckhard Boles and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-06-16 with Science categories.
All living cells are strictly separated from their surroundings by a membranous lipid bilayer. Into these membranes a variety of transport proteins are embedded that ensure the uptake and secretion of various molecules and ions. In order to respond properly to a changing nutrient supply or demand, as well as to external stress factors, cells must be able to adapt both amount and activity of the corresponding transporters. This book provides readers with state-of-the-art knowledge on the various regulatory mechanisms that control transmembrane transporter expression, activity and their subcellular localisation.
Molecular Mechanisms Of Membrane Traffic
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Author : D. James Morre
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Molecular Mechanisms Of Membrane Traffic written by D. James Morre and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
The study of membrane traffic in reconstituted cell-free systems has generated an unprecedented amount of new information on the biochemistry, molecular biology and genetics of membrane-based molecular events that underly normal and abnormal cellular function. Many of the individual steps have now been isolated and dissected in simple systems that permit detailed molecular analyses of transport mechanisms and their regulation. Reconstituted events of intercompartment transport include inter-membrane recognition, and controlled membrane fusion-fission reactions. Among the many advances is the growi ng awareness of a remarkabl e evolutionary conservation of many of the components involved in the many steps of membrane traffic, this realization has accelerated greatly the pace of progress in the field. This book provides a collection of participant contributions from the 1992 Summer Research Conference, "Mol ecul ar Mechani sms of Membrane Traffi c, " jointly sponsored with NATO by the American Society of Cell Biology. The conference was held May 9-13, at the Airlie Conference Center in the Virginia countryside, near Warrenton. The conference was attended by 158 scientists. A unique feature was the high proportion of young scientists among the participants. Approximately 65% were students, postdoctoral fe 11 ows and young investigators. Each attendee contri buted to the conference with either a pl atform or poster presentation.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Molecular Mechanisms Of Water Transport Across Biological Membranes
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Author : Wilfred D. Stein
language : en
Publisher: Gulf Professional Publishing
Release Date : 2002-04-02
Molecular Mechanisms Of Water Transport Across Biological Membranes written by Wilfred D. Stein and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-04-02 with Science categories.
International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. This volume looks at water movements from a wide range of levels. It examines how water interacts with the major components of the cell, including proteins and lipids. It discusses how water moves across cell membranes by diffusion, how it is chanelled across these membranes or, in certain cases, pumped across, and how water movements are controlled. This book demonstrates how water and ion movements are closely linked in order to provide a better understanding of their behavior. *Essential Physical chemistry of water at biological interfaces *Up-to-date reviews of water behavior in cells *Water in integrated systems *Current information on water channels across membranes
Capturing Atomic Level Mechanisms For Membrane Transport And Signaling With Biomolecular Simulation
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Author : Naomi Rose Latorraca
language : en
Publisher:
Release Date : 2019
Capturing Atomic Level Mechanisms For Membrane Transport And Signaling With Biomolecular Simulation written by Naomi Rose Latorraca and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.
Proteins embedded in cell membranes translate a broad range of environmental cues--including the presence of nutrients, drugs, ions and photons--into molecular signals to induce appropriate cellular responses. Membrane proteins thus represent a control panel of the cell and constitute key drug targets for the treatment of a range of diseases. Designing medications to effectively modulate these proteins, however, remains exceedingly challenging and would benefit dramatically from an atomic-level understanding of how these proteins work. Here, I have used molecular dynamics (MD) simulations--which describe how every atom in a biological system evolves with high resolution in space and time--to reveal functional mechanisms for transporters and receptors, two essential classes of membrane proteins. This approach allowed us to address several long-standing questions in molecular biology. For example, we captured the complete process of substrate translocation through an alternating-access membrane transporter. These simulations, which revealed structural rearrangements in the protein that control substrate passage across the membrane as well as the driving forces underlying those transitions, suggest a structural foundation for the design of highly specific and more efficacious transporter-targeted medications. We also revealed the mechanism by which G protein--coupled receptors stimulate arrestins, intracellular regulators of cell signaling. By identifying atomic-level interactions at the GPCR--arrestin interface that drive arrestin activation, we provide a framework for designing drugs that could selectively block or stimulate arrestin signaling, thereby reducing unwanted side effects. In each study, we worked closely with our experimental collaborators to validate predictions derived from our computational results.
Membrane Transport In Plants And Fungi
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Author : Society for Experimental Biology (Great Britain)
language : en
Publisher:
Release Date : 1994
Membrane Transport In Plants And Fungi written by Society for Experimental Biology (Great Britain) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Biological transport categories.
Receptors Membrane Transport And Signal Transduction
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Author : A.E. Evangelopoulos
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Receptors Membrane Transport And Signal Transduction written by A.E. Evangelopoulos and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
A NATO Advanced study Institute on "Receptors, Membrane Trans port and Signal Transduction", was held on the Island of Spet sai, Greece, from August 16-27, 1988, in order to consider re cent developments in membrane receptor research, membrane trans port and signal transduction mechanisms. These topics were put in the larger context of current knowledge on the structure and function of membranes; connections between different fields of research were established by in-depth dis cussions of energy transduction and transport mechanisms. The general principles of regulation by signal transduction and protein phosphorylation/dephosphorylation were presented in the context of specific cellular processes. Discussions included al so the role of protein tyrosine kinases which are structurally related to oncogene products and, therefore, implicated in va rious aspects of cell development and transformation. This book presents the content of the major lectures and a se lection of the most relevant posters presented during the course of the Institute. The book is intended to make the proceedings of the Institute accessible to a larger audience and to offer a comprehensive account of those topics on receptors, membrane transport and signal transduction that were discussed extensive ly during the course of the Institute. February 1989 The Editors CONTENTS I. G-PROTEINS, ADENYLATE CYCLASE AND PROTEIN PHOSPHORYLATION Selective regulation of G proteins by Cell surface receptors ......... .
Molecular Mechanisms Of Signal Transduction
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Author : Johannes Lukas Bos
language : en
Publisher: IOS Press
Release Date : 2000
Molecular Mechanisms Of Signal Transduction written by Johannes Lukas Bos and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Science categories.
This book contains overviews of topics that have been discussed. It includes contributions from leading experts in the field on small GTPases, protein kinesis, receptors and transcription factors. A particular focus was the influence of oxygen radicals on signalling processes. It also contains the contributions of scientists early in their career, who have made an excellent contribution to the institute.