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Molecular Pathogenesis And Signal Transduction By Helicobacter Pylori


Molecular Pathogenesis And Signal Transduction By Helicobacter Pylori
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Molecular Pathogenesis And Signal Transduction By Helicobacter Pylori


Molecular Pathogenesis And Signal Transduction By Helicobacter Pylori
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Author : Nicole Tegtmeyer
language : en
Publisher: Springer
Release Date : 2017-01-23

Molecular Pathogenesis And Signal Transduction By Helicobacter Pylori written by Nicole Tegtmeyer and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-23 with Medical categories.


This volume reviews the current state of research concerning bacterial virulence factors and the infection biology of Helicobacter pylori, which is the leading cause of peptic ulcers and gastric cancer worldwide. The chapters include cutting-edge findings on this fascinating microbe and discuss the general strategies of H. pylori infection and persistence, news on important H. pylori virulence factors, crosstalk with the microbiota, hot novel models and signaling mechanisms, risk factors of gastric disease and stomach cancer, and the impact of H. pylori infection on non-gastric diseases. Written by internationally respected scientists, this book will appeal to clinicians, researchers and advanced students alike.



Helicobacter Pylori Biology And Clinical Practice


Helicobacter Pylori Biology And Clinical Practice
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Author : C. Stewart Goodwin
language : en
Publisher: CRC Press
Release Date : 2018-01-18

Helicobacter Pylori Biology And Clinical Practice written by C. Stewart Goodwin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Science categories.


Helicobacter pylori: Biology and Clinical Practice is the first book to fully describe H. pylori and the pathogenesis of H. pylori infections. It delineates the genome of H. pylori, discusses the molecular biology of the unique urease enzyme, and examines the clinical application of these discoveries. The book describes the epidemiology of H. pylori and its relevance to gastric cancer, and it offers clear guidance to clinicians for the diagnosis and treatment of peptic ulcer and non-ulcer dyspepsia in adults and children. Vaccine principles and possibilities are presented for the first time. Edited by the leader of the microbiology team that achieved the first culture of H. pylori, and named the Helicobacter genus, this book is essential for bacteriologists, gastroenterologists, microbiologists, infectious disease specialists, and other researchers interested in H. pylori.



Helicobacter Pylori In The 21st Century


Helicobacter Pylori In The 21st Century
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Author : Philip Sutton
language : en
Publisher: CABI
Release Date : 2010

Helicobacter Pylori In The 21st Century written by Philip Sutton and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.


This book provides a broad overview of the current understanding of Helicobacter pylori emphasizing its world health impacts. It includes 13 chapters organized into 3 parts: "Pathologies and Treatment", "Host Response" and "Bacterial Defence". Part I (5 chapters) reviews the epidemiology of H. pylori infection, H. pylori infection in Asia, gastric adenocarcinoma, antimicrobial resistance and approaches to treatment, and extragastric manifestations of H. pylori infection. Part II (4 chapters) describes H. pylori-induced acquired immunity and immunoregulation, host genetic factors and susceptibility to H. pylori pathogenesis, innate immune initiators and effectors in H. pylori infection, and H. pylori vaccines. Part III (4 chapters) discusses the importance of H. pylori lipopolysaccharides in gastric adaptation and pathogenesis, H. pylori virulence factors, H. pylori adhesion to the gastric surface, and helicobacteromics. This book is an essential resource for researchers, students and medics in infectious and Helicobacter-associated diseases.



Molecular Pathogenesis Of Gastrointestinal Infections


Molecular Pathogenesis Of Gastrointestinal Infections
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Author : T. Wadström
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-08

Molecular Pathogenesis Of Gastrointestinal Infections written by T. Wadström and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-08 with Medical categories.


The meeting that provided the material for this book was the 58th Symposium of the Federation of European Microbiological Societies (FEMS) entitled MOLECULAR PATHOGENESIS OF GASTROINTESTINAL INFECTIONS which was held in Helsingor, Denmark from 2nd to 4th September, 1990. The aim of this meeting was to bring together scientists from a range of discipline- microbiology, cell biology, molecular biology and immunology - to consider how microbes, including parasites, colonize and infect the gastrointestinal tract. The programme was designed to focus particular attention on the range of strategies whereby enterovirulent bacteria and parasites colonize the gastrointestinal mucin layer, how they adhere to and penetrate the epithelial layer by entering the cells or passing between them, and how various protein toxins may facilitate these processes. Speakers were especially encouraged to highlight the recent expansion in our knowledge of the molecular mechanisms by which enterotoxigenic and enteropathogenic Escherichia coli, shigellae, salmonellae and Yersinia enterocolitica cause intestinal disease. There were also discussions of recently-discovered gastrointestinal pathogens such as Clostridium difficile and Helicobacter pylori as well as accounts of how virulent determinants can be used to develop new diagnostic methods based on DNA gene probes and the polymerase chain reaction (PCR). These presentations provided the basis for the chapters in this book.



Ending The War Metaphor


Ending The War Metaphor
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2006-07-09

Ending The War Metaphor written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-07-09 with Medical categories.


Infectious diseases have existed longer than us, as long as us, or are relatively newer than us. It may be the case that a disease has existed for many, many years but has only recently begun affecting humans. At the turn of the century the number of deaths caused by infections in the United States had been falling steadily but since the '80s has seen an increase. In the past 30 years alone 37 new pathogens have been identified as human disease threats and 12% of known human pathogens have been classified as either emerging or remerging. Whatever the story, there is currently a "war" on infectious diseases. This war is simply the systematic search for the microbial "cause" of each disease, followed by the development of antimicrobial therapies. The "war" on infectious diseases, however, must be revisited in order to develop a more realistic and detailed picture of the dynamic interactions among and between host organisms and their diverse populations of microbes. Only a fraction of these microbes are pathogens. Thus, in order to explore the crafting of a new metaphor for host-microbe relationships, and to consider how such a new perspective might inform and prioritize biomedical research, the Forum on Microbial Threats of the Institute of Medicine (IOM) convened the workshop, Ending the War Metaphor: The Changing Agenda for Unraveling the Host-Microbe Relationship on March 16-17, 2005. Workshop participants examined knowledge and approaches to learning about the bacterial inhabitants of the human gut, the best known host-microbe system, as well as findings from studies of microbial communities associated with other mammals, fish, plants, soil, and insects. The perspective adopted by this workshop is one that recognizes the breadth and diversity of host-microbe relationships beyond those relative few that result in overt disease. Included in this summary are the reports and papers of individuals participating in the Forum as well as the views of the editors.



Helicobacter Pylori


Helicobacter Pylori
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Author : Yoshio Yamaoka
language : en
Publisher: Caister Academic Press Limited
Release Date : 2008

Helicobacter Pylori written by Yoshio Yamaoka and has been published by Caister Academic Press Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Science categories.


Helicobacter pylori is an important human pathogen that infects up to 50% of the human population. As the leading cause of peptic ulcers, gastritis, and gastric cancer worldwide, the organism has been the subject of intensive research to unravel the mysteries of its genetics and cellular biology. In fact, the number of publications in this field has risen dramatically in recent years making it extremely difficult for even the most diligent reader to stay abreast of progress. This book distills the most important cutting-edge findings in the field to produce a timely and comprehensive review. With contributions from leading international helicobacter researchers, topics include: lipopolysaccharides, outer membrane proteins, motility and chemotaxis, type IV secretions systems, metal metabolism, molecular mechanisms of host adaptation, genomotyping, and proteonomics. As a useful introduction to the subject for new researchers and as an invaluable reference for the experienced researcher, this book is essential reading for all researchers working with Helicobacter and related organisms.



Type Iv Secretion In Gram Negative And Gram Positive Bacteria


Type Iv Secretion In Gram Negative And Gram Positive Bacteria
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Author : Steffen Backert
language : en
Publisher: Springer
Release Date : 2018-03-13

Type Iv Secretion In Gram Negative And Gram Positive Bacteria written by Steffen Backert and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-13 with Medical categories.


Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host cell functions to trigger bacterial uptake, promote intracellular growth, suppress defense mechanisms and of how bacteria spread antibiotic resistances, thus facilitating bacterial colonization and disease development. The book is an invaluable source of information for researchers and clinicians.



Wnt Signaling In Immune Cell Regulation During Microbial Infection And Cancer


Wnt Signaling In Immune Cell Regulation During Microbial Infection And Cancer
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Author : Malini Sen
language : en
Publisher: Frontiers Media SA
Release Date : 2020-07-14

Wnt Signaling In Immune Cell Regulation During Microbial Infection And Cancer written by Malini Sen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-14 with categories.




Gastritis


Gastritis
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Author : Bruna Maria Roesler
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-12-18

Gastritis written by Bruna Maria Roesler and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-18 with Medical categories.


The isolation and identification of Helicobacter pylori as the cause of gastrointestinal diseases had major implications for public health and led to curative treatments that reduced suffering from many acute and chronic conditions. Although alternative therapies have been used to improve eradication, current treatments still rely on a combination of antimicrobial agents often associated with antisecretory agents, such as proton pump inhibitors. In this book there is a comprehensive overview by contributors on H. pylori infection in diverse areas, including a general overview of H. pylori infection, and discussions about the principal therapeutic regimens of bacterium eradication, considering antimicrobial resistance. Also, certain aspects of autoimmune gastritis, an important condition that has been related to microorganism infection, is also considered. H. pylori is clearly a very interesting bacterium and great studies and discussions about all its aspects are welcomed by the medical and scientific communities.



Helicobacter Pylori Research


Helicobacter Pylori Research
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Author : Steffen Backert
language : en
Publisher: Springer
Release Date : 2018-05-27

Helicobacter Pylori Research written by Steffen Backert and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-27 with Medical categories.


This book provides the current updated knowledge on all essential aspects in the rapidly evolving area of Helicobacter pylori research. H. pylori is a class I carcinogen and one of the most common infections in the world. While most people colonized by H. pylori will remain asymptomatic, up to 20 % of them may develop serious gastroduodenal disease such as peptic ulcers or gastric cancer. H. pylori is the only known bacterium linked to the development of cancer and consequently is an important focus of research. Outstanding international experts from diverse scientific disciplines contribute here to give detailed insights into the current understanding concerning the physiology and role of this pathogen. Both basic science and clinical research with actual practical consequences are taken into account. The chapters target microbiology, epidemiology, genetics, biochemistry, interactions with the immune system, signal transduction, pathogenic mechanisms in the gastroduodenal mucosa, gastric disease development, and therapy including antibiotics or probiotics treatment as well as vaccination strategies. This book is an important reference not only for clinicians but also microbiologists. It provides in a single volume an up-to-date summary of our current knowledge of this microbe and the multiple ways in which it impacts upon public health in all parts of the world.