Molecular Pathology Of The Pituitary


Molecular Pathology Of The Pituitary
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Molecular Pathology Of The Pituitary


Molecular Pathology Of The Pituitary
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Author : George Kontogeorgos
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2004-01-01

Molecular Pathology Of The Pituitary written by George Kontogeorgos and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-01 with Medical categories.


Molecular pathology, a newly emerging field of research, is providing a deeper insight and understanding of the pituitary structure and its function in health and disease. This volume covers the basic principles of molecular pathology and summarizes the current knowledge of pituitary development as well as pituitary adenoma morphology and pathogenesis. Molecular, state-of-the-art techniques currently used for research and clinical applications are presented and the results of these fascinating and sophisticated modern tools are illustrated. The contents cover topics such as the mechanisms involved in pituitary development and cytogenesis, tumor development and functional differentiation, cell death, the molecular cytogenetics of defective genes and chromosomes, and pituitary tumor formation and progression. The contributors all are internationally well-known and esteemed experts. The chapters are comprehensive and up to date and focus on recent advances and should stimulate further studies. The present volume of Frontiers of Hormone Research will be of particular interest not only to basic scientists, but also pathologists, clinical endocrinologists and neurosurgeons.



Molecular Pathology Of Pituitary Adenomas


Molecular Pathology Of Pituitary Adenomas
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Author : Cristiana Tanase
language : en
Publisher: Elsevier
Release Date : 2011-10-31

Molecular Pathology Of Pituitary Adenomas written by Cristiana Tanase and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-31 with Medical categories.


The pituitary gland is an important one since it controls several of the other hormone glands, such as the thyroid and adrenals. A pituitary adenoma is an abnormal growth or tumor in this gland, and they are the subject of very active clinical and pathological research. This book examines the latest developments in this field and discusses the most important molecules implicated in apoptosis, angiogenesis and signal transduction. A good understanding of these processes is needed to identify the best therapies. Facilitates the understanding of the processes involved and how they are translated into therapy Illustrations are used to explain the complex mechanisms involved



Pituitary Today Ii


Pituitary Today Ii
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Author : Eduardo Arzt
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2010-01-01

Pituitary Today Ii written by Eduardo Arzt and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-01 with Medical categories.


Update on basic and clinical research on pituitary function and disease.



Molecular Pathology Of Endocrine Diseases


Molecular Pathology Of Endocrine Diseases
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Author : Jennifer L. Hunt
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-05-17

Molecular Pathology Of Endocrine Diseases written by Jennifer L. Hunt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-17 with Medical categories.


The past two decades have seen an ever accelerating growth in knowledge about molecular pathology of human diseases, which received a large boost with the sequencing of the human genome in 2003. Mole- lar diagnostics, molecular targeted therapy, and genetic therapy are now routine in many medical centers. The molecular field now impacts every field in medicine, whether clinical research or routine patient care. There is a great need for basic researchers to understand the potential clinical implications of their research whereas private practice clinicians of all types (general internal medicine and internal medicine specialists, medical oncologists, radiation oncologists, surgeons, pediatricians, family practitioners), clinical inves- gators, pathologists and medical laboratory directors, and radiologists require a basic understanding of the fundamentals of molecular pathogenesis, diagnosis, and treatment for their patients. Traditional textbooks in molecular biology deal with basic science and are not readily applicable to the medical setting. Most medical textbooks that include a mention of molecular pathology in the clinical setting are limited in scope and assume that the reader already has a working knowledge of the basic science of molecular biology. Other texts emphasize technology and testing procedures without integrating the clinical perspective. There is an urgent need for a text that fills the gap between basic science books and clinical practice.



Surgical Pathology Of The Pituitary Gland


Surgical Pathology Of The Pituitary Gland
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Author : Ricardo V. Lloyd
language : en
Publisher: W.B. Saunders Company
Release Date : 1993

Surgical Pathology Of The Pituitary Gland written by Ricardo V. Lloyd and has been published by W.B. Saunders Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.


Intended for pathologists and endocrinologists, this book covers the diagnosis, surgical and medical treatment of pituitary adenomas. It includes special techniques used to study pituitary adenomas, including electron microscopy, cell culture and molecular biology. The text combines traditional morphologic approaches with more recent information derived from studies with the tools of the new biology. It combines extensive coverage of diagnosis with various aspects of the pituitary adenomas. The integrated approach provides a foundation for making specific diagnoses of pituitary disorders and also indicates the future directions of pituitary pathology. The emphasis is on diagnostic criteria for pituitary tumours. Chapters on medical and surgical management of pituitary adenomas provide a balanced perspective on the approach to the patient with pituitary tumours.



Oncogenesis And Molecular Biology Of Pituitary Tumors


Oncogenesis And Molecular Biology Of Pituitary Tumors
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Author : Shlomo Melmed
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 1996

Oncogenesis And Molecular Biology Of Pituitary Tumors written by Shlomo Melmed and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.


This comprehensive volume focuses on mechanisms leading to pituitary tumor formation and progression. The individual chapters provide timely updates on developments in the rapidly expanding field of pituitary tumor pathogenesis. Researchers from leading centers describe the fundamental functional anatomy of the pituitary, the structure and function of the hypothalamic hormone receptors as they relate to human pituitary adenomas, as well as disordered transcription factors, growth factors and signaling proteins in pituitary tumorigenesis. They also present transgenic models of pituitary tumor formation and report on chromosomal deletions observed in both hereditary and sporadic adenomas. The book is an essential and timely resource for basic and clinical endocrinologists, neurosurgeons and neuro-oncologists as it provides a state-of-the-art summary of our current understanding of the pathogenesis of these common tumors.



Gigantism And Acromegaly


Gigantism And Acromegaly
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Author : Constantine A. Stratakis
language : en
Publisher: Academic Press
Release Date : 2021-06-01

Gigantism And Acromegaly written by Constantine A. Stratakis and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-01 with Medical categories.


Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim’s appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. Accessible, up-to-date overview of the characteristics, state-of-the-art diagnostic procedures, and management of acromegaly and gigantism Provides a unique compendium of endocrinology, genetics, clinical diagnosis and therapeutics Contains contributions from internationally known experts who have treated patients with acromegaly and gigantism



The Pituitary


The Pituitary
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Author : Shlomo Melmed
language : en
Publisher: Academic Press
Release Date : 2010-12-09

The Pituitary written by Shlomo Melmed and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-09 with Medical categories.


The pituitary, albeit a small gland, is known as the "master gland" of the endocrine system and contributes to a wide spectrum of disorders, diseases, and syndromes. Since the publication of the second edition of The Pituitary, in 2002, there have been major advances in the molecular biology research of pituitary hormone production and action and there is now a better understanding of the pathogenesis of pituitary tumors and clinical syndromes resulting in perturbation of pituitary function. There have also been major advances in the clinical management of pituitary disorders. Medical researchers and practitioners now better understand the morbidity and mortality associated with pituitary hormone hyposecretion and hypersecretion. Newly developed drugs, and improved methods of delivering established drugs, are allowing better medical management of acromegaly and prolactinoma. These developments have improved the worldwide consensus around the definition of a "cure" for pituitary disease, especially hormone hypersecretion, and hence will improve the success or lack of success of various forms of therapy. It is therefore time for a new edition of The Pituitary. The third edition will continue to be divided into sections that summarize normal hypothalamic-pituitary development and function, hypothalamic-pituitary failure, and pituitary tumors; additional sections will describe pituitary disease in systemic disorders and diagnostic procedures, including imaging, assessment of the eyes, and biochemical testing. The first chapter will be completely new – placing a much greater emphasis on physiology and pathogenesis. Two new chapters will be added on the Radiation and Non-surgical Management of the Pituitary and Other Pituitary Lesions. Other chapters will be completely updated and many new author teams will be invited. The second edition published in 2002 and there have been incredible changes in both the research and clinical aspects of the pituitary over the past 8 years – from new advances in growth hormones to pituitary tumor therapy. Presents a comprehensive, translational source of information about the pituitary in one reference work Pituitary experts (from all areas of research and practice) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches Clear presentation by endocrine researchers of the cellular and molecular mechanisms underlying pituitary hormones and growth factors as well as new techniques used in detecting lesions (within the organ) and other systemic disorders Clear presentation by endocrinologists and neuroendocrine surgeons of how imaging, assessment of the eyes, and biochemical testing can lead to new therapeutic approaches



Endocrine Pathology


Endocrine Pathology
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Author : Virginia A. Livolsi
language : en
Publisher:
Release Date : 2002

Endocrine Pathology written by Virginia A. Livolsi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Endocrine glands categories.


This full-color benchside reference covers the complete spectrum of issues related to the pathology of endocrine glands and organs. Over 20 international experts bring you superior coverage of the neoplastic and non-neoplastic diseases that affect the pituitary, thyroid, parathyroid, paraganglia and adrenal medulla, gastrointestinal tract, pancreas, and neuroendocrine lung. They also address endocrine active lesions of the ovary, testis, skin, and placenta. Each chapter discusses general pathology, gross morphology, histology, immunohistochemistry and cytology, and includes coverage of flow cytometry, genetics, and molecular biology where appropriate.



Tumors Of The Central Nervous System Volume 10


Tumors Of The Central Nervous System Volume 10
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Author : M.A. Hayat
language : en
Publisher: Springer
Release Date : 2012-12-22

Tumors Of The Central Nervous System Volume 10 written by M.A. Hayat and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-22 with Medical categories.


Adding to a vitally important cycle of publications covering the latest research developments in our understanding of neoplasms affecting the human central nervous system, this edition focuses on numerous aspects of pineal, pituitary, and spinal tumors. As with the previous volumes in the series, this latest work addresses a central imperative in cancer research—the need to standardize classifications, written definitions and investigative guidelines in order to achieve a measure of shared objectivity among academics engaged in one of the most important medical endeavors of our era. It brings together the very latest work by oncologists, neurosurgeons, physicians, research scientists, and pathologists, providing the medical community with a wealth of data and results that, taken together, will advance the cause of cancer research. The volume synthesizes work on diagnosis, drug development, and therapeutic approaches that are typically scattered in a variety of journals and books. It features promising recent work in applying molecular genetics to clinical practice and evidence-based therapy, covering molecular profiling of tumors as well as a number of surgical treatments such as resection and radiosurgery. Together with its counterpart publications, it represents a much-needed central resource that will inform and guide future research efforts.