Molecular Recognition Of Dna Double Helix

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Molecular Recognition Of Dna Double Helix

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Author : Abhijit Saha
language : en
Publisher: Springer
Release Date : 2018-03-22

Molecular Recognition Of Dna Double Helix written by Abhijit Saha and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-22 with Science categories.

In this book, the molecular recognition of DNA using small molecules is discussed, with a study of the photochemistry of BrU-labeled DNA. The purposes of the study were to develop small molecules for regenerative medicine, to develop a method to detect the recognition site of small molecules, and to detect the most important biological phenomena using the photochemistry of BrU-labeled DNA. The study began with the design and development of small molecules that can induce pluripotency genes. To deal with the important issue of cell permeability of the original compound, a new analogue of the original with improved gene expression was designed and synthesized. Using the photochemistry of BrU-labeled DNA, crucial biological phenomena such as cooperativity between transcription factors were detected. For the first time, the cooperativity was examined by excess electron transfer assay. DNA was also studied very carefully in order to understand the mechanism of the double-strand break in the UVA micro-irradiation technique. The mechanism of the double strand remained untouched. Nevertheless, the double-strand break mechanism was clearly demonstrated by Hoechst dye, as shown in this book.

Molecular Recognition Within The Minor Groove Of The Dna Double Helix

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Author : Paul Richard Evans
language : en
Publisher:
Release Date : 1997

Molecular Recognition Within The Minor Groove Of The Dna Double Helix written by Paul Richard Evans and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with DNA. categories.

Recent Trends In Molecular Recognition

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Author : F. Diederich
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17

Recent Trends In Molecular Recognition written by F. Diederich and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Science categories.

Reasoning in terms of molecular recognition may be traced back to Emil Fischer, who practiced the art of chemistry at Humboldt University in Prussian Berlin a century ago. Today, it is clearly recognized that molecular recognition impacts and determines all life processes. It has become a key research field in both chemistry and biology and the emerging interface of what now is being called "chemical biology". The technological advances derived from this knowledge are particularly important, diverse, and directly evident in the pharmaceutical industry. Under the auspices of the Ernst Schering Research Foundation, a workshop held in Berlin in February 1998 addressed novel basic developments of potential relevance to drug research efforts. A balance of timely research topics in molecular recognition is presented in the lectures delivered by a multidisciplinary international panel of renowned scholars and documented in this volume.

Molecular Recognition Of Dna Synthesis Of Novel Bases For Triple Helix Formation

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Author :
language : en
Publisher:
Release Date : 1991

Molecular Recognition Of Dna Synthesis Of Novel Bases For Triple Helix Formation written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with categories.

Molecular Recognition Of Proteins And Dna

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Author : Ho Leung Ng
language : en
Publisher:
Release Date : 2001

Molecular Recognition Of Proteins And Dna written by Ho Leung Ng and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.

Dna Structure And Recognition

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Author : Stephen Neidle
language : en
Publisher: Oxford University Press, USA
Release Date : 1994

Dna Structure And Recognition written by Stephen Neidle and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Literary Criticism categories.

This book is a concise, comprehensive survey of DNA structure, from first principles to the ways in which drugs and proteins interact with DNA. Such an understanding of DNA structure is essential for more detailed study in areas such as gene regulation and DNA-targeted drug action.

Molecular Biology Of The Cell

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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002

Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.

Molecular Recognition By Anti Dna Autoantibodies

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Author : Shawn Yvette Stevens
language : en
Publisher:
Release Date : 1997

Molecular Recognition By Anti Dna Autoantibodies written by Shawn Yvette Stevens and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with categories.

Advances In Dna Sequence Specific Agents

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Author : Laurence H. Hurley
language : en
Publisher: Elsevier Science Limited
Release Date : 1996

Advances In Dna Sequence Specific Agents written by Laurence H. Hurley and has been published by Elsevier Science Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Science categories.

DNA sequence specificity is a sub-specialty in the general area of molecular recognition. This area includes macromolecular-molecular interactions (e.g., protein-DNA), oligomer-DNA interacitons (e.g., triple strands), and ligand-DNA interactions (e.g., drug-DNA). It is this latter group of DNA sequence specificity interactions that is the subject of Volumes 1 and 2 of Advances in DNA Sequence Specific Agents. As was the case for Volume 1, Part A also covers methodology, but in Volume 2 we include calorimetric titrations, molecular modeling, X-ray crystallographic and NMR structural studies, and transcriptional assays. Part B also follows the same format as Volume 1 and describes the sequence specificities and covalent and noncovalent interactions of small ligands with DNA. This volume is aimed in general at scientists who have an interest in deciphering the molecular mechanisms for sequence recognition of DNA. The methods have general applicability to small molecules as well as oligomers and proteins, while the examples provide general principles involved in sequence recognition.

Structural Dna Nanotechnology

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Author : Nadrian C. Seeman
language : en
Publisher: Cambridge University Press
Release Date : 2015

Structural Dna Nanotechnology written by Nadrian C. Seeman and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Computers categories.

Written by the founder of the field, this is a comprehensive and accessible introduction to structural DNA nanotechnology.