Molecular Science Of Fluctuations Toward Biological Functions
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Molecular Science Of Fluctuations Toward Biological Functions
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Author : Mazahide Terazima
language : en
Publisher: Springer
Release Date : 2016-02-09
Molecular Science Of Fluctuations Toward Biological Functions written by Mazahide Terazima and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-09 with Science categories.
In this monograph, the importance of fluctuations for biological reactions is discussed from various points of view. Understanding the biological reactions at the molecular level is one of the major targets in many scientific fields, including not only basic biology but also physics, physical chemistry, and medical science. One of the key factors in the process is “fluctuation”. Thermal energy causes biological molecules to be in constant fluctuation even while they are carrying out their biological functions. How do biological systems overcome the thermal fluctuations to realize the physiologically relevant reactions? Scientists in a number of fields—physics, chemistry, pharmacology, medicine, and others—have contributed chapters that elucidate the nature of the fluctuations and the relationship between fluctuations and biological functions. The fluctuations discussed in this volume are detected by the transient grating method, nuclear magnetic resonance, X-ray diffraction and scattering, and computer simulation, among other methods. The book presents various results of the studies of fluctuations in biological processes that were obtained with these methods by the leading scientists in their fields.
Molecular Theory Of Fluctuation In Life Phenomena
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Author : Fumio Hirata
language : en
Publisher: Springer Nature
Release Date : 2025-04-24
Molecular Theory Of Fluctuation In Life Phenomena written by Fumio Hirata and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-24 with Science categories.
This book describes molecular processes taking place in living cells, in which “water” or “solvation” play essential roles. The molecular processes include conformational stability, fluctuation, relaxation, self-organization, molecular recognition, and chemical reactions. In all those processes, so-called solvation free-energy, and its first and second derivatives with respect to the atomic coordinates of biomolecules play key roles. Such derivatives of the free energy may not be calculated by any method of molecular simulation, because the calculation requires an analytical formula of the solvation free energy as a function of the atomic coordinates of a biomolecule. In this book, the theory is applied to analyze phenomena closely related to the conformational and density fluctuation of biomolecular systems, including the entropy and spectroscopy of both biomolecules and solvents. The theory is further developed to give microscopic expressions to the well-regarded phenomenological theories of chemical reactions, including the Michaelis–Menten theory of the enzymatic reaction, and the theory of the electron-transfer reaction by R. Marcus. Also clarified in the book is physical basis of Anfinsen’s hypothesis concerning the protein folding. This book is beneficial for graduate students and researchers in the field of life science and technology, especially for those studying pharmaceutical design and biomimetic technology such as artificial enzymes.
Memoirs Of The Institute Of Scientific And Industrial Research Osaka University
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Author : Ōsaka Daigaku. Sangyō Kagaku Kenkyūjo
language : en
Publisher:
Release Date : 2011
Memoirs Of The Institute Of Scientific And Industrial Research Osaka University written by Ōsaka Daigaku. Sangyō Kagaku Kenkyūjo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Research categories.
Advances In Chemical Physics Volume 137
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Author : Stuart A. Rice
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-30
Advances In Chemical Physics Volume 137 written by Stuart A. Rice and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-30 with Science categories.
The Advances in Chemical Physics series provides the chemical physics field with a forum for critical, authoritative evaluations of advances in every area of the discipline. This special volume focuses on atoms and photos near meso- and nanobodies, an important area of nontechnology. Nanoscale particles are those between 1 and 100 nm, and they obey neither the laws of quantum physics nor of classical physics due to an extensive delocalization of the valence electrons, which can vary depending on size. This means that different physical properties can be obtained from the same atoms or molecules existing in a nanoscale particle size due entirely to differing sizes and shapes. Nanostructured materials have unique optical, magnetic, and electronic properties depending on the size and shape of the nanomaterials. A great deal of interest has surfaced in this arena as of late due to the potential technological applications.
Science
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Author : John Michels (Journalist)
language : en
Publisher:
Release Date : 2011
Science written by John Michels (Journalist) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.
Exploring Life Phenomena With Statistical Mechanics Of Molecular Liquids
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Author : Fumio Hirata
language : en
Publisher: CRC Press
Release Date : 2020-02-12
Exploring Life Phenomena With Statistical Mechanics Of Molecular Liquids written by Fumio Hirata and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-12 with History categories.
In a living body, a variety of molecules are working in a concerted manner to maintain its life, and to carry forward the genetic information from generation to generation. A key word to understand such processes is "water," which plays an essential role in life phenomena. This book sheds light on life phenomena, which are woven by biomolecules as warp and water as weft, by means of statistical mechanics of molecular liquids, the RISM and 3D-RISM theories, both in equilibrium and non-equilibrium. A considerable number of pages are devoted to basics of mathematics and physics, so that students who have not majored in physics may be able to study the book by themselves. The book will also be helpful to those scientists seeking better tools for the computer-aided-drug-discovery. Explains basics of the statistical mechanics of molecular liquids, or RISM and 3D-RISM theories, and its application to water. Provides outline of the generalized Langevin theory and the linear response theory, and its application to dynamics of water. Applies the theories to functions of biomolecular systems. Applies the theories to the computer aided drug design. Provides a perspective for future development of the method.
Comprehensive Foodomics
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Author :
language : en
Publisher: Elsevier
Release Date : 2020-11-12
Comprehensive Foodomics written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-12 with Science categories.
Comprehensive Foodomics, Three Volume Set offers a definitive collection of over 150 articles that provide researchers with innovative answers to crucial questions relating to food quality, safety and its vital and complex links to our health. Topics covered include transcriptomics, proteomics, metabolomics, genomics, green foodomics, epigenetics and noncoding RNA, food safety, food bioactivity and health, food quality and traceability, data treatment and systems biology. Logically structured into 10 focused sections, each article is authored by world leading scientists who cover the whole breadth of Omics and related technologies, including the latest advances and applications. By bringing all this information together in an easily navigable reference, food scientists and nutritionists in both academia and industry will find it the perfect, modern day compendium for frequent reference. List of sections and Section Editors: Genomics - Olivia McAuliffe, Dept of Food Biosciences, Moorepark, Fermoy, Co. Cork, Ireland Epigenetics & Noncoding RNA - Juan Cui, Department of Computer Science & Engineering, University of Nebraska-Lincoln, Lincoln, NE Transcriptomics - Robert Henry, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, Australia Proteomics - Jens Brockmeyer, Institute of Biochemistry and Technical Biochemistry, University Stuttgart, Germany Metabolomics - Philippe Schmitt-Kopplin, Research Unit Analytical BioGeoChemistry, Neuherberg, Germany Omics data treatment, System Biology and Foodomics - Carlos Leon Canseco, Visiting Professor, Biomedical Engineering, Universidad Carlos III de Madrid Green Foodomics - Elena Ibanez, Foodomics Lab, CIAL, CSIC, Madrid, Spain Food safety and Foodomics - Djuro Josic, Professor Medicine (Research) Warren Alpert Medical School, Brown University, Providence, RI, USA & Sandra Kraljevic Pavelic, University of Rijeka, Department of Biotechnology, Rijeka, Croatia Food Quality, Traceability and Foodomics - Daniel Cozzolino, Centre for Nutrition and Food Sciences, The University of Queensland, Queensland, Australia Food Bioactivity, Health and Foodomics - Miguel Herrero, Department of Bioactivity and Food Analysis, Foodomics Lab, CIAL, CSIC, Madrid, Spain Brings all relevant foodomics information together in one place, offering readers a ‘one-stop,’ comprehensive resource for access to a wealth of information Includes articles written by academics and practitioners from various fields and regions Provides an ideal resource for students, researchers and professionals who need to find relevant information quickly and easily Includes content from high quality authors from across the globe
Water
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Author : Hidenao Fukuyama
language : en
Publisher: Pan Stanford Publishing
Release Date : 2010-11-30
Water written by Hidenao Fukuyama and has been published by Pan Stanford Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-30 with Medical categories.
The main objective of this book is to bring together multidisciplinary contributions from leading authorities on the properties and roles of water in cell systems which are otherwise dispersed in the literature and difficult to gather. The authors are drawn from areas of physics, chemistry, biology and physiology, where water plays a central role. The book focuses on current research and developments in the theoretical and experimental studies of water in biological systems and compounds, such as interaction with hydrophobic or hydrophilic structures, protein and membrane surfaces. It provides insights into the importance of water in cellular processes and physiology and, ultimately, in life, brain function, and health.
Encyclopedia Of Cell Biology
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-08-07
Encyclopedia Of Cell Biology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-07 with Science categories.
The Encyclopedia of Cell Biology, Four Volume Set offers a broad overview of cell biology, offering reputable, foundational content for researchers and students across the biological and medical sciences. This important work includes 285 articles from domain experts covering every aspect of cell biology, with fully annotated figures, abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, the Encyclopedia of Cell Biology provides a fully cross-referenced, one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences. Fully annotated color images and videos for full comprehension of concepts, with layered content for readers from different levels of experience Includes information on cytokinesis, cell biology, cell mechanics, cytoskeleton dynamics, stem cells, prokaryotic cell biology, RNA biology, aging, cell growth, cell Injury, and more In-depth linking to Academic Press/Elsevier content and additional links to outside websites and resources for further reading A one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences
Physics Of Bio Molecules And Cells
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Author : Henrik Flyvbjerg
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-07-01
Physics Of Bio Molecules And Cells written by Henrik Flyvbjerg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-07-01 with Science categories.
Aimed at those working to enter this rapidly developing field, this volume on biological physics is written in a pedagogical style by leading scientists giving explanations that take their starting point where any physicist can follow and end at the frontier of research in biological physics. These lectures describe the state-of-the-art physics of biomolecules and cells. In biological systems ranging from single biomolecules to entire cells and larger biological systems, it focuses on aspects that require concepts and methods from physics for their analysis and understanding, such as the mechanics of motor proteins; how the genetic code is physically read and managed; the machinery of protein--DNA interactions; force spectroscopy of biomolecules' velopes, cytoskeletons, and cytoplasms; polymerization forces; listeria propulsion; cell motility; lab-on-a-chip nanotechnology for single-molecule analysis of biomolecules; bioinformatics; and coding and computational strategies of the brain.