Molybdenum Cofactors And Their Role In The Evolution Of Metabolic Pathways
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Molybdenum Cofactors And Their Role In The Evolution Of Metabolic Pathways
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Author : Luana Presta
language : en
Publisher: Springer
Release Date : 2015-05-07
Molybdenum Cofactors And Their Role In The Evolution Of Metabolic Pathways written by Luana Presta and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-07 with Science categories.
In this brief, the authors explore and review the current knowledge regarding the role of molybdenum in the evolution of biological systems and their interaction with biogeochemical cycles. Special emphasis is placed on biological nitrogen fixation and the nitrogen element cycle. The origin and evolution of molybdenum cofactor biosynthetic pathways as well as the evolutionary significance of molybdenum containing enzymes appearance is analyzed. Original data regarding nitrogen fixation pathways and related enzymes molecular evolution processes is presented. The trace element molybdenum is essential for nearly all organisms and forms the catalytic center of a large variety of enzymes such as nitrogenase, nitrate reductases, sulphite oxidase and xanthine oxidoreductases.
Molybdenum Enzymes
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Author : Thomas G. Spiro
language : en
Publisher: Wiley-Interscience
Release Date : 1985-11-14
Molybdenum Enzymes written by Thomas G. Spiro and has been published by Wiley-Interscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985-11-14 with Science categories.
Volume 7 in the Metal Ions in Biology Series, divided into two parts, covers the nitrogenase enzyme complex and the molybdenum redox enzymes. Part one covers the chemistry of Mo-Fe-S clusters and their relationship to nitrogenase, cofactor chemistry and biochemistry of nitrogenase, spectroscopic and electrochemical studies of the Fe-Mo cofactor and Fe-S clusters, and more. Part Two surveys oxo-molybdenum chemistry, discusses the nature of the molybdo-pterin complex, and describes the characteristics of several of the Mo redox enzymes.
Redox Biochemistry
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Author : Ruma Banerjee
language : en
Publisher: John Wiley & Sons
Release Date : 2007-12-04
Redox Biochemistry written by Ruma Banerjee and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-04 with Science categories.
This is the premier, single-source reference on redox biochemistry, a rapidly emerging field. This reference presents the basic principles and includes detailed chapters focusing on various aspects of five primary areas of redox biochemistry: antioxidant molecules and redox cofactors; antioxidant enzymes; redox regulation of physiological processes; pathological processes related to redox; and specialized methods. This is a go-to resource for professionals in pharmaceuticals, medicine, immunology, nutrition, and environmental fields and an excellent text for upper-level students.
Mitochondria And Anaerobic Energy Metabolism In Eukaryotes
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Author : William F. Martin
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2020-12-07
Mitochondria And Anaerobic Energy Metabolism In Eukaryotes written by William F. Martin and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-07 with Science categories.
Mitochondria are sometimes called the powerhouses of eukaryotic cells, because mitochondria are the site of ATP synthesis in the cell. ATP is the universal energy currency, it provides the power that runs all other life processes. Humans need oxygen to survive because of ATP synthesis in mitochondria. The sugars from our diet are converted to carbon dioxide in mitochondria in a process that requires oxygen. Just like a fire needs oxygen to burn, our mitochondria need oxygen to make ATP. From textbooks and popular literature one can easily get the impression that all mitochondria require oxygen. But that is not the case. There are many groups of organismsm known that make ATP in mitochondria without the help of oxygen. They have preserved biochemical relicts from the early evolution of eukaryotic cells, which took place during times in Earth history when there was hardly any oxygen avaiable, certainly not enough to breathe. How the anaerobic forms of mitochondria work, in which organisms they occur, and how the eukaryotic anaerobes that possess them fit into the larger picture of rising atmospheric oxygen during Earth history are the topic of this book.
Recent Advances In Trace Elements
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Author : Katarzyna Chojnacka
language : en
Publisher: John Wiley & Sons
Release Date : 2018-02-23
Recent Advances In Trace Elements written by Katarzyna Chojnacka and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-23 with Science categories.
Comprehensive and multidisciplinary presentation of the current trends in trace elements for human, animals, plants, and the environment This reference provides the latest research into the presence, characterization, and applications of trace elements and their role in humans, animals, and plants as well as their use in developing novel, functional feeds, foods, and fertilizers. It takes an interdisciplinary approach to the subject, describing the biological and industrial applications of trace elements. It covers various topics, such as the occurrence, role, and monitoring of trace elements and their characterization, as well as applications from the preliminary research to laboratory trials. Recent Advances in Trace Elements focuses on the introduction and prospects of trace elements; tackles environmental aspects such as sources of emission, methods of monitoring, and treatment/remediation processes; goes over the biological role of trace elements in plants, animals, and human organisms; and discusses the relevance of biomedical applications and commercialization. A compendium of recent knowledge in interdisciplinary trace element research Uniquely covers production and characterization of trace elements, as well as the industrial and biomedical aspects of their use Paves the way for the development of innovative products in diverse fields, including pharmaceuticals, food, environment, and materials science Edited by well-known experts in the field of trace elements with contributions from international specialists from a wide range of areas Unique in presenting comprehensive and multidisciplinary information of the key aspects of trace elements research in a digestible form, this book is essential reading for the novice and expert in the fields of environmental science, analytical chemistry, biochemistry, materials science, pharmaceutical science, nutraceutical, and pharmaceutical sciences. It is also valuable for companies that implement new products incorporating trace elements to the market.
Biomarkers In Inborn Errors Of Metabolism
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Author : Uttam Garg
language : en
Publisher: Elsevier
Release Date : 2017-06-07
Biomarkers In Inborn Errors Of Metabolism written by Uttam Garg and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-07 with Medical categories.
Biomarkers of Inborn Errors in Metabolism: Clinical Aspects and Laboratory Determination is structured around the new reality that laboratory testing and biomarkers are an integral part in the diagnosis and treatment of inherited metabolic diseases. The book covers currently used biomarkers as well as markers that are in development. Because biomarkers used in the initial diagnosis of disease may be different than the follow-up markers, the book also covers biomarkers used in both the prognosis and treatment of inherited metabolic disorders. With the introduction of expanded new-born screening for inborn metabolic diseases, an increasing numbers of laboratories are involved in follow-up confirmatory testing. The book provides guidance on laboratory test selection and interpreting results in patients with suspected inherited metabolic diseases. The book provides comprehensive guidance on patient diagnosis and follow-up through its illustrative material on metabolic pathways, genetics and pathogenesis, treatment and prognosis of inherited metabolic diseases, along with essential information on clinical presentation. Each chapter is organized with a uniform, easy-to-follow format: a brief description of the disorder and pathway; a description of treatment; biomarkers for diagnosis; biomarkers followed for treatment efficacy; biomarkers followed for disease progression; confounding conditions that can either: affect biomarker expression or mimic IEMs; other biomarkers: less established, future. Provides comprehensive information on the tests/biomarkers selection in newborn screening and follow-up of newborn screens Categorizes biomarkers into diagnostic markers, disease follow-up markers, and prognostic biomarkers Covers confounding factors that can alter biomarkers in the absence of inborn errors of metabolism Offers guidance on how to distinguish acquired causes from inborn errors of metabolism
Prokaryotic Metabolism And Physiology
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Author : Byung Hong Kim
language : en
Publisher: Cambridge University Press
Release Date : 2019-05-16
Prokaryotic Metabolism And Physiology written by Byung Hong Kim and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-16 with Medical categories.
Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.
Physician S Guide To The Diagnosis Treatment And Follow Up Of Inherited Metabolic Diseases
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Author : Nenad Blau
language : en
Publisher: Springer
Release Date : 2014-07-08
Physician S Guide To The Diagnosis Treatment And Follow Up Of Inherited Metabolic Diseases written by Nenad Blau and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-08 with Medical categories.
This book, combining and updating two previous editions, is a unique source of information on the diagnosis, treatment, and follow-up of metabolic diseases. The clinical and laboratory data characteristic of rare metabolic conditions can be bewildering for both clinicians and laboratory personnel. Reference laboratory data are scattered, and clinical descriptions may be obscure. The Physician’s Guide documents the features of more than five hundred conditions, grouped according to type of disorder, organ system affected (e.g. liver, kidney, etc) or phenotype (e.g. neurological, hepatic, etc). Relevant clinical findings are provided and pathological values for diagnostic metabolites highlighted. Guidance on appropriate biochemical genetic testing is provided. Established experimental therapeutic protocols are described, with recommendations on follow-up and monitoring. The authors are acknowledged experts, and the book will be a valuable desk reference for all who deal with inherited metabolic diseases.
Enzymes For Solving Humankind S Problems
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Author : José J. G. Moura
language : en
Publisher: Springer Nature
Release Date : 2020-12-01
Enzymes For Solving Humankind S Problems written by José J. G. Moura and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-01 with Science categories.
This book presents specific key natural and artificial systems that are promising biocatalysts in the areas of health, agriculture, environment and energy. It provides a comprehensive account of the state of the art of these systems and outlines the significant progress made in the last decade using these systems to develop innovative, sustainable and environmentally friendly solutions. Chapters from expert contributors explore how natural enzymes and artificial systems tackle specific targets such as: climate change, carbon footprint and economy and carbon dioxide utilisation; nitrogen footprint and fixation and nitrous oxide mitigation; hydrogen production, fuel cells and energy from bacteria; biomass transformation and production of added-value compounds, as well as biosensors development. This book provides an important and inspiring account for the designing of new natural and artificial systems with enhanced properties, and it appeals not only to students and researchers working in the fields of energy, health, food and environment, but also to a wider audience of educated readers that are interested in these up-to-date and exciting subjects. Chapter “Carbon Dioxide Utilisation—The Formate Route” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Progressive Brain Disorders In Childhood
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Author : Juan M. Pascual
language : en
Publisher: Cambridge University Press
Release Date : 2017-04-20
Progressive Brain Disorders In Childhood written by Juan M. Pascual and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-20 with Medical categories.
A review of childhood neurodegenerative and other progressive but non-degenerative disorders to guide their diagnosis and management.