Moving From Covid 19 Mathematical Models To Vaccine Design Theory Practice And Experiences

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Moving From Covid 19 Mathematical Models To Vaccine Design Theory Practice And Experiences
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Author : Andrés Fraguela-Collar
language : en
Publisher: Bentham Science Publishers
Release Date : 2022-09-05
Moving From Covid 19 Mathematical Models To Vaccine Design Theory Practice And Experiences written by Andrés Fraguela-Collar and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-05 with Medical categories.
This compendium represents a set of guides to understanding the challenging scientific, epidemiological, clinical, social, and economic phenomenon that is represented by the COVID-19 pandemic. The book explains the mathematical modeling of COVID-19 infection, with emphasis on traditional epidemiological principles. It represents a rigorous, comprehensive and multidisciplinary approach to a complex phenomenon. The chapters take into account the knowledge arising from different disciplines (epidemiology, pathophysiology, immunology, medicine, biology, vaccine development, etc.). It also covers COVID-19 data analysis, giving the reader a perspective of statistics and data science, and includes a discussion about social and economic issues of the pandemic. Each chapter is devoted to a specific topic, and is contributed by experts in epidemiology. Because of its multidisciplinary nature, this book is intended as a reference on mathematical models and basic immunotherapy for COVID-19 for a broad community of readers, from scholars who have scientific training, to general readers who have an interest in the disease.
Mathematical Epidemiology
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Author : Fred Brauer
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-04-30
Mathematical Epidemiology written by Fred Brauer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-30 with Medical categories.
Based on lecture notes of two summer schools with a mixed audience from mathematical sciences, epidemiology and public health, this volume offers a comprehensive introduction to basic ideas and techniques in modeling infectious diseases, for the comparison of strategies to plan for an anticipated epidemic or pandemic, and to deal with a disease outbreak in real time. It covers detailed case studies for diseases including pandemic influenza, West Nile virus, and childhood diseases. Models for other diseases including Severe Acute Respiratory Syndrome, fox rabies, and sexually transmitted infections are included as applications. Its chapters are coherent and complementary independent units. In order to accustom students to look at the current literature and to experience different perspectives, no attempt has been made to achieve united writing style or unified notation. Notes on some mathematical background (calculus, matrix algebra, differential equations, and probability) have been prepared and may be downloaded at the web site of the Centre for Disease Modeling (www.cdm.yorku.ca).
Primary Mathematics
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Author : Penelope Serow
language : en
Publisher: Cambridge University Press
Release Date : 2014-01-20
Primary Mathematics written by Penelope Serow and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-20 with Education categories.
Primary Mathematics provides a comprehensive introduction to teaching and learning mathematics in today's classrooms. Drawing links to the Australian Curriculum, this book covers the core learning areas of measurement, space and geometry, early number concepts, data and statistics, chance and probability, and patterns and algebra. At the centre of this book is the belief that ICT can be a powerful tool for enhancing student learning. Although many classrooms have been resourced with computers, interactive whiteboards and mobile technology, teachers need to be able to transform these technological tools into meaningful teaching and learning experiences. This book explores the ways in which technology can be integrated into the mathematics classroom. The book also explores issues around student diversity, assessment 'for', 'of' and 'as' learning, and teaching in rural and remote areas. Primary Mathematics is an indispensable resource for pre- and in-service teachers alike.
The Rules Of Contagion
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Author : Adam Kucharski
language : en
Publisher: Basic Books
Release Date : 2020-07-07
The Rules Of Contagion written by Adam Kucharski and has been published by Basic Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-07 with Business & Economics categories.
One of the Best Books of 2020 — Financial Times One of the "Most 2020 Books of 2020" — Washington Post One of the Best Science Books of 2020 — The Times of London One of the Best Science Books of 2020 — The Guardian From ideas and infections to financial crises and fake news, an "utterly timely" look at why the science of outbreaks is the science of modern life These days, whenever anything spreads, whether it's a YouTube fad or a political rumor, we say it went viral. But how does virality actually work? In The Rules of Contagion, epidemiologist Adam Kucharski explores topics including gun violence, online manipulation, and, of course, outbreaks of disease to show how much we get wrong about contagion, and how astonishing the real science is. Why did the president retweet a Mussolini quote as his own? Why do financial bubbles take off so quickly? Why are disinformation campaigns so effective? And what makes the emergence of new illnesses -- such as MERS, SARS, or the coronavirus disease COVID-19 -- so challenging? By uncovering the crucial factors driving outbreaks, we can see how things really spread -- and what we can do about it. Whether you are an author seeking an audience, a defender of truth, or simply someone interested in human social behavior, The Rules of Contagion is an essential guide to modern life.
An Introduction To Infectious Disease Modelling
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Author : Emilia Vynnycky
language : en
Publisher: Oxford University Press, USA
Release Date : 2010-05-13
An Introduction To Infectious Disease Modelling written by Emilia Vynnycky and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-13 with Language Arts & Disciplines categories.
Mathematical models are increasingly used to guide public health policy decisions and explore questions in infectious disease control. Written for readers without advanced mathematical skills, this book provides an introduction to this area.
Epidemic Models
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Author : Denis Mollison
language : en
Publisher: Cambridge University Press
Release Date : 1995-07-13
Epidemic Models written by Denis Mollison and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-07-13 with Mathematics categories.
Surveys the state of epidemic modelling, resulting from the NATO Advanced Workshop at the Newton Institute in 1993.
Modeling Infectious Diseases In Humans And Animals
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Author : Matt J. Keeling
language : en
Publisher: Princeton University Press
Release Date : 2011-09-19
Modeling Infectious Diseases In Humans And Animals written by Matt J. Keeling and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-19 with Science categories.
For epidemiologists, evolutionary biologists, and health-care professionals, real-time and predictive modeling of infectious disease is of growing importance. This book provides a timely and comprehensive introduction to the modeling of infectious diseases in humans and animals, focusing on recent developments as well as more traditional approaches. Matt Keeling and Pejman Rohani move from modeling with simple differential equations to more recent, complex models, where spatial structure, seasonal "forcing," or stochasticity influence the dynamics, and where computer simulation needs to be used to generate theory. In each of the eight chapters, they deal with a specific modeling approach or set of techniques designed to capture a particular biological factor. They illustrate the methodology used with examples from recent research literature on human and infectious disease modeling, showing how such techniques can be used in practice. Diseases considered include BSE, foot-and-mouth, HIV, measles, rubella, smallpox, and West Nile virus, among others. Particular attention is given throughout the book to the development of practical models, useful both as predictive tools and as a means to understand fundamental epidemiological processes. To emphasize this approach, the last chapter is dedicated to modeling and understanding the control of diseases through vaccination, quarantine, or culling. Comprehensive, practical introduction to infectious disease modeling Builds from simple to complex predictive models Models and methodology fully supported by examples drawn from research literature Practical models aid students' understanding of fundamental epidemiological processes For many of the models presented, the authors provide accompanying programs written in Java, C, Fortran, and MATLAB In-depth treatment of role of modeling in understanding disease control
Reinforcement Learning And Optimal Control
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Author : Dimitri Bertsekas
language : en
Publisher: Athena Scientific
Release Date : 2019-07-01
Reinforcement Learning And Optimal Control written by Dimitri Bertsekas and has been published by Athena Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-01 with Computers categories.
This book considers large and challenging multistage decision problems, which can be solved in principle by dynamic programming (DP), but their exact solution is computationally intractable. We discuss solution methods that rely on approximations to produce suboptimal policies with adequate performance. These methods are collectively known by several essentially equivalent names: reinforcement learning, approximate dynamic programming, neuro-dynamic programming. They have been at the forefront of research for the last 25 years, and they underlie, among others, the recent impressive successes of self-learning in the context of games such as chess and Go. Our subject has benefited greatly from the interplay of ideas from optimal control and from artificial intelligence, as it relates to reinforcement learning and simulation-based neural network methods. One of the aims of the book is to explore the common boundary between these two fields and to form a bridge that is accessible by workers with background in either field. Another aim is to organize coherently the broad mosaic of methods that have proved successful in practice while having a solid theoretical and/or logical foundation. This may help researchers and practitioners to find their way through the maze of competing ideas that constitute the current state of the art. This book relates to several of our other books: Neuro-Dynamic Programming (Athena Scientific, 1996), Dynamic Programming and Optimal Control (4th edition, Athena Scientific, 2017), Abstract Dynamic Programming (2nd edition, Athena Scientific, 2018), and Nonlinear Programming (Athena Scientific, 2016). However, the mathematical style of this book is somewhat different. While we provide a rigorous, albeit short, mathematical account of the theory of finite and infinite horizon dynamic programming, and some fundamental approximation methods, we rely more on intuitive explanations and less on proof-based insights. Moreover, our mathematical requirements are quite modest: calculus, a minimal use of matrix-vector algebra, and elementary probability (mathematically complicated arguments involving laws of large numbers and stochastic convergence are bypassed in favor of intuitive explanations). The book illustrates the methodology with many examples and illustrations, and uses a gradual expository approach, which proceeds along four directions: (a) From exact DP to approximate DP: We first discuss exact DP algorithms, explain why they may be difficult to implement, and then use them as the basis for approximations. (b) From finite horizon to infinite horizon problems: We first discuss finite horizon exact and approximate DP methodologies, which are intuitive and mathematically simple, and then progress to infinite horizon problems. (c) From deterministic to stochastic models: We often discuss separately deterministic and stochastic problems, since deterministic problems are simpler and offer special advantages for some of our methods. (d) From model-based to model-free implementations: We first discuss model-based implementations, and then we identify schemes that can be appropriately modified to work with a simulator. The book is related and supplemented by the companion research monograph Rollout, Policy Iteration, and Distributed Reinforcement Learning (Athena Scientific, 2020), which focuses more closely on several topics related to rollout, approximate policy iteration, multiagent problems, discrete and Bayesian optimization, and distributed computation, which are either discussed in less detail or not covered at all in the present book. The author's website contains class notes, and a series of videolectures and slides from a 2021 course at ASU, which address a selection of topics from both books.
An Introduction To Inverse Problems With Applications
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Author : Francisco Duarte Moura Neto
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-09-14
An Introduction To Inverse Problems With Applications written by Francisco Duarte Moura Neto and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-14 with Mathematics categories.
Computational engineering/science uses a blend of applications, mathematical models and computations. Mathematical models require accurate approximations of their parameters, which are often viewed as solutions to inverse problems. Thus, the study of inverse problems is an integral part of computational engineering/science. This book presents several aspects of inverse problems along with needed prerequisite topics in numerical analysis and matrix algebra. If the reader has previously studied these prerequisites, then one can rapidly move to the inverse problems in chapters 4-8 on image restoration, thermal radiation, thermal characterization and heat transfer. “This text does provide a comprehensive introduction to inverse problems and fills a void in the literature”. Robert E White, Professor of Mathematics, North Carolina State University
Design And Analysis Of Vaccine Studies
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Author : M. Elizabeth Halloran
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-10-27
Design And Analysis Of Vaccine Studies written by M. Elizabeth Halloran and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-27 with Medical categories.
As well as being a reference for the design, analysis, and interpretation of vaccine studies, the text covers all design and analysis stages, from vaccine development to post-licensure surveillance, presenting likelihood, frequentists, and Bayesian approaches.