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Mr Linac Radiotherapy


Mr Linac Radiotherapy
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A Practical Guide To Mr Linac


A Practical Guide To Mr Linac
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Author : Indra J. Das
language : en
Publisher: Springer Nature
Release Date :

A Practical Guide To Mr Linac written by Indra J. Das and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.




Mr Linac Radiotherapy


Mr Linac Radiotherapy
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Author : Sara L. Hackett
language : en
Publisher: Academic Press
Release Date : 2022-12-01

Mr Linac Radiotherapy written by Sara L. Hackett and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-01 with Science categories.


MR Linac Radiotherapy: A New Personalized Treatment Approach comprises both clinical and physical aspects of this new technology. The book covers treatment planning, workflow and technical issues about MR-Linac. Specially, the clinical use of MR-Linac according to different cancer types is presented by experienced physicians. This is a unique guide for medical physicists, RTTs, dosimetrists and physicians, as well as radiation oncologists and their teams. The MR Linac combines two technologies - a magnetic resonance imaging scanner and a linear accelerator - to precisely locate tumors, tailor the shape of radiation beams in real-time, and precisely deliver doses of radiation, even to moving tumors. This highly innovative technology is very new, and the number of newly installed MR-Linac machines will gradually increase worldwide. However, as there is no published book as a guideline, this book will help new MR-Linac users and centers planning to have MR-Linac. Presents the first book on MR Linac Radiotherapy Comprises both clinical and physical aspects of this new technology Written by leading editors and authors in the field



Online Adaptive Mr Guided Radiotherapy


Online Adaptive Mr Guided Radiotherapy
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Author : Linda G. W. Kerkmeijer
language : en
Publisher: Frontiers Media SA
Release Date : 2021-10-18

Online Adaptive Mr Guided Radiotherapy written by Linda G. W. Kerkmeijer and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-18 with Medical categories.




Radiation Therapy Using Mri Linac The Right Way To Start A Guide For Physicians And Physicists


Radiation Therapy Using Mri Linac The Right Way To Start A Guide For Physicians And Physicists
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Author : Merav Ben-David
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-02

Radiation Therapy Using Mri Linac The Right Way To Start A Guide For Physicians And Physicists written by Merav Ben-David and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-02 with Medical categories.




Mri For Radiotherapy


Mri For Radiotherapy
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Author : Gary Liney
language : en
Publisher: Springer
Release Date : 2019-06-20

Mri For Radiotherapy written by Gary Liney and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-20 with Medical categories.


This book provides, for the first time, a unified approach to the application of MRI in radiotherapy that incorporates both a physics and a clinical perspective. Readers will find detailed information and guidance on the role of MRI in all aspects of treatment, from dose planning, with or without CT, through to response assessment. Extensive coverage is devoted to the latest technological developments and emerging options. These include hybrid MRI treatment systems, such as MRI-Linac and proton-guided systems, which are ushering in an era of real-time MRI guidance. The past decade has witnessed an unprecedented rise in the use of MRI in the radiation treatment of cancer. The development of highly conformal dose delivery techniques has led to a growing need to harness advanced imaging for patient treatment. With its flexible soft tissue contrast and ability to acquire functional information, MRI offers advantages at all stages of treatment. In documenting the state of the art in the field, this book will be of value to a wide range of professionals. The authors are international experts drawn from the scientific committee of the 2017 MR in RT symposium and the faculty of the ESTRO teaching course on imaging for physicists.



Establishing Clinical Cancer Treatments With Mr Guided Adaptive Radiotherapy


Establishing Clinical Cancer Treatments With Mr Guided Adaptive Radiotherapy
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Author : Marcel Nachbar
language : en
Publisher:
Release Date : 2022

Establishing Clinical Cancer Treatments With Mr Guided Adaptive Radiotherapy written by Marcel Nachbar and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.


The advances in image guided radiotherapy (IGRT) lead to an significant increase in treatment quality of cancer patients. However the guidance of radiotherapy based on X-Ray shows limitations and never translated into online adaptive radiotherapy. Therefore the new concept of MR-guided radiotherapy (MRgRT) was introduced, combining an linear accelerator with a magnetic resonance imaging (MRI). In this hybrid MR-linac system the higher soft tissue contrast of the MRI in combination with an optimization on the anatomy of the day promises increased treatment quality and new standard of practice. However, a MRI has before only supplied additional offline information for the annotation of tumor tissue and an online adaptive workflow was not part of clinical treatments. Therefore the challenges in regard to the magnetic field effect on dose distributions, algorithms and measurement devices as well as the problems due to the online adaptive workflow have not been investigated. In this work, the medical physics basis of MR-guided radiotherapy (MRgRT) was researched and concluded in safe clinical treatments of patients. In a first step the technical drawbacks were researched in a simulation study comparing the possible dose distribution for esophageal cancer between the MR-linac system and a modern state of the art linear accelerator. This simulation study showed the dosimetric drawbacks of the MR-linac system due to loss of conformality and size limitations. In addition we showed, that greater focus has to be put on mid- and low-dose areas and that the corresponding OARs must be included into optimization. However, we showed as well that by adaptation of the optimization, the clinical parameters can be fulfilled leading to feasibility of treatment plans. In a second step the only existing algorithm for calculation of dose distributions at the 1.5 T MR-Linac was compared to a detailed research Monte Carlo (MC) system, due to possible approximations on behalf of the magnetic field and attenuating layers of the MRI. In this investigation the detailed MC-simulation was designed to incorporate the material specific information of the accelerator and MRI and their corresponding cross sections for an exact dose calculation. With an iterative comparison to experimental data the linac specific free parameters were derived and the independent accelerator head model finalized for a validation of patient treatments. This validation showed, with gamma criterion of 3 mm and 3% a passing rate of 99.83 % and therefore validated that the approximations do not correspond to a significant change in dose distribution. In a third step new quality assurances were developed to allow treatment of patients on the MR-linac system. For an experimental measurement of dose deposition a novel workflow was developed and integrated, as the conventional systems showed high influences by the static magnetic field. Based on the characterization, a 2D ionization chamber inside a hexagonal phantom can accurately measure the applied dose and, by comparison with the respective simulation, assure correct machine calibration. For an comprehensive check of online adaptive plans within a treatment workflow an independent secondary dose calculation was established. Based on an independent build Monte Carlo accelerator head and a 3D comparison of dose distributions this secondary dose calculation can verify clinical plans in a median time of 1:23 min. In this comparison of dose distributions a gamma criterion validates the machine parameters and assures correct dose over the full patient anatomy. In the final step the acquired knowledge from the previous studies and developed quality assurances allowed first treatments of patients with online adaptive MRguided radiotherapy. In this dissertation the first worldwide MR-guided treatment of partial breast stands representative to the multitude of different tumor entities initiated at the MR-linac system. Equivalent to the investigations on ERE, ESE and geometric distortion in partial breast, further tumor specific magnetic field effects were evaluated for an assessment of potential risks. With this work the basis for a safe treatment with MR-guided radiotherapy (MRgRT) was developed. Therefore, as methods and respective handling of magnetic field effects are now established, new clinical concepts are being developed starting the next phase of MRgRT improving patient treatments in radiotherapy by deviating from current clinical practice.



Three Dimensional Dose Verification Of Adaptive Radiotherapy At An Mr Linac


Three Dimensional Dose Verification Of Adaptive Radiotherapy At An Mr Linac
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Author : Filipa Costa
language : en
Publisher:
Release Date : 2020

Three Dimensional Dose Verification Of Adaptive Radiotherapy At An Mr Linac written by Filipa Costa and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.




Adaptive Radiation Therapy


Adaptive Radiation Therapy
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Author : X. Allen Li
language : en
Publisher: CRC Press
Release Date : 2011-01-27

Adaptive Radiation Therapy written by X. Allen Li and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-27 with Medical categories.


Modern medical imaging and radiation therapy technologies are so complex and computer driven that it is difficult for physicians and technologists to know exactly what is happening at the point-of-care. Medical physicists responsible for filling this gap in knowledge must stay abreast of the latest advances at the intersection of medical imaging an



Image Guided High Precision Radiotherapy


Image Guided High Precision Radiotherapy
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Author : Esther G. C. Troost
language : en
Publisher: Springer Nature
Release Date : 2022-10-11

Image Guided High Precision Radiotherapy written by Esther G. C. Troost and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-11 with Medical categories.


This book equips readers with detailed knowledge on the current status of image-guided radiotherapy with photons and particles and highlights issues that need to be addressed in order to further improve treatment outcomes. The opening chapters cover clinical and technical aspects of target volume definition using anatomic (computed tomography and magnetic resonance imaging; MRI) as well as functional (MRI and positron emission tomography) imaging. Up-to-date information is then provided on the full range of image-guided high-precision radiotherapy techniques, including IMRT/VMAT, stereotactic body radiation therapy, MR-guided linear accelerators, MR-guided brachytherapy, and particle therapy. The role of ultrasonography in image-guided radiotherapy is discussed, as are the available means for target volume demarcation and stabilization and adaptive radiation therapy. Finally, outcome evaluation is explored in depth, with a particular focus on the role of multimodality imaging in predicting tumor control and normal tissue toxicity. The authors are experts in different specialties and the book will be of high value for radiation oncologists, medical physicists, radiologists, nuclear medicine physicians, and radiation technicians.



4d Mri For Thoracic Radiotherapy Treatment Planning And Guidance On An Mr Linac


4d Mri For Thoracic Radiotherapy Treatment Planning And Guidance On An Mr Linac
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Author : Joshua Freedman
language : en
Publisher:
Release Date : 2019

4d Mri For Thoracic Radiotherapy Treatment Planning And Guidance On An Mr Linac written by Joshua Freedman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.