Mrna Vaccine
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Mrna Vaccine
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Author : Fouad Sabry
language : en
Publisher: One Billion Knowledgeable
Release Date : 2022-10-05
Mrna Vaccine written by Fouad Sabry and has been published by One Billion Knowledgeable this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-05 with Medical categories.
What Is mRNA Vaccine The immunological response that is induced by a vaccination known as an mRNA vaccine is brought about by the administration of a replica of a molecule known as messenger RNA (mRNA). The vaccine inserts molecules of mRNA that encode antigens into immune cells. The immune cells then utilize the engineered mRNA as a template to construct a foreign protein similar to one that would typically be generated by a cancer cell or a disease. These protein molecules activate an adaptive immune response, which educates the body to detect and eliminate the matching cancer cells or pathogens. Adaptive immune responses have been shown to be more effective than traditional immune responses. The delivery of the mRNA is accomplished by the use of a co-formulation that consists of the RNA being encased in lipid nanoparticles. These nanoparticles serve to preserve the RNA strands and assist in their uptake into the cells. How You Will Benefit (I) Insights, and validations about the following topics: Chapter 1: mRNA vaccine Chapter 2: Vaccine Chapter 3: PEGylation Chapter 4: Solid lipid nanoparticle Chapter 5: Moderna Chapter 6: COVID-19 vaccine Chapter 7: Moderna COVID-19 vaccine Chapter 8: Jason McLellan Chapter 9: BioNTech Chapter 10: RNA therapeutics Chapter 11: Pfizer-BioNTech COVID-19 vaccine Chapter 12: Özlem Türeci Chapter 13: Nucleoside-modified messenger RNA Chapter 14: ALC-0315 Chapter 15: Distearoylphosphatidylcholine Chapter 16: SM-102 Chapter 17: Deployment of COVID-19 vaccines Chapter 18: History of COVID-19 vaccine development Chapter 19: CureVac COVID-19 vaccine Chapter 20: N1-Methylpseudouridine Chapter 21: COVID-19 vaccine clinical research (II) Answering the public top questions about mRNA vaccine. (III) Real world examples for the usage of mRNA vaccine in many fields. (IV) 17 appendices to explain, briefly, 266 emerging technologies in each industry to have 360-degree full understanding of mRNA vaccine' technologies. Who This Book Is For Professionals, undergraduate and graduate students, enthusiasts, hobbyists, and those who want to go beyond basic knowledge or information for any kind of mRNA vaccine.
Mrna Vaccines
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Author : Dong Yu
language : en
Publisher: Springer Nature
Release Date : 2023-01-03
Mrna Vaccines written by Dong Yu and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-03 with Medical categories.
The formulation and the technological advancements in RNA biology, chemistry, stability, and encapsulated delivery systems that have enabled the development of fully synthetic mRNA vaccines are discussed in this volume. The applications of the mRNA technology is covered, focusing on infectious diseases but also touching on other indications, such as immunotherapies and molecular therapies. Potent and long-lasting immune responses observed in animal models, encouraging data from early human clinical studies, together with the success of two mRNA-based COVID-19 vaccines support the use of mRNA-based vaccination as an attractive alternative to conventional vaccine approaches. Consequently, the development progress of the technology, particularly on production, capabilities, and clinical development is reviewed. Topics on safety, regulatory issues, and possible challenges to the mRNA vaccination approach round off this book. Thanks to their high potency, the prospect for generic, low-cost manufacturing processes, and entirely synthetic nature, the future for mRNA vaccines is highly promising. Importantly, mRNA vaccines have the potential to minimize the time between pathogen identification and vaccine release with a huge impact on public health. As the mRNA-based vaccination technology has been progressing rapidly, the book is intended to be an end-to-end review series, covering everything from basic RNA biology and preclinical studies to the manufacturing strategy, clinical development and regulatory approval. It provides established RNA researchers and developers with updates on the latest advancements in the field and allows for a quick but comprehensive overview of this transformative technology, its application, and future potential.
Mrna Covid 19 Vaccine The Human Gm Frontier
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Author : Mikolaj Kuca
language : en
Publisher:
Release Date : 2020-12-29
Mrna Covid 19 Vaccine The Human Gm Frontier written by Mikolaj Kuca and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-29 with categories.
There is great concern and uncertainty about the new type of vaccines. Mainly, the COVID-19 vaccine, as this is the first one so broadly tested and used. Previously, there were attempts to create mRNA vaccines for flu and rabies. Those tests were continuing since 2013. Due to the unprecedented situation, there is a world-wide acceptance of the need to use all available tools in the fight against COVID-19, and the greatest hope is for the mRNA vaccine. There is also another great genetics technology on the table: CRISPR. Both will reshape the world as we know it in the near future - nearer than we could possibly expect. Marvel stories might turn into reality quite unexpectedly. When I started my work with mRNA technology over 20 years ago, I did not expect such major advancements to happen so quickly. In this book the new mRNA technology will be explained in closer detail, yet in as simple language as possible. The concerns, hopes, and the future of this technique will be addressed, in order to make more people aware of the change that they will soon see.
Mrna Therapeutics
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Author : Sarfaraz K. Niazi
language : en
Publisher: CRC Press
Release Date : 2022-12-06
Mrna Therapeutics written by Sarfaraz K. Niazi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-06 with Medical categories.
This book is the most comprehensive and complete treatise on nucleic acid therapeutic products, including mRNA vaccines, their manufacturing, formulations, and testing for safety and efficacy. Details include cGMP-compliant manufacturing and regulatory filing steps. A new concept of “biosimilar” mRNA vaccine is presented to secure fast approval of copies of mRNA vaccines. Projections of financial plans to establish RNA manufacturing facilities are provided, along with details of supply chain management. Finally, the future of nucleic acid products in gene therapy and other newer applications is presented, along with a perspective that all new vaccines will be the nucleic acid type that will further provide first-time prevention of autoimmune disorders. It is projected that both big pharma and start-ups will enter this field, and we can expect significant additions to our drug armamentarium soon.
The Marathon Of The Messenger
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Author : Jérôme Lemonnier
language : en
Publisher: Springer Nature
Release Date : 2023-12-03
The Marathon Of The Messenger written by Jérôme Lemonnier and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-03 with Medical categories.
The Covid-19 pandemic changed the world. Indeed a real race took place worldwide between SARS-CoV-2 on the one hand and researchers on the other – especially those specializing in messenger RNA vaccines. Four years after its emergence, the pandemic is not over, but some decisive battles have been won, thanks to the great success of mRNA vaccines. The Marathon of The Messenger presents the history of these mRNA vaccines, combining a scientific background with historical and economic perspectives. It appears that an important page in the history of these new vaccines was written in Europe, thanks to the crucial work of German and French scientists; this effort began in 1993 and continues to this day. In the face of a prevailing single-mindedness, these researchers pushed through a new therapeutic concept and defined the biotechnological keys that would open the way to the production of therapeutic messenger RNA in the fight against cancer and viral infections. Written for a broad audience and accompanied by humorous cartoons, this book will appeal to anyone looking for scientific and historical answers about mRNA vaccines. Readers will discover not only the technical and scientific knowledge of how these vaccines work, but also the economic levers that were necessary to create this technology. This book has been written in collaboration with Dr. Steve Pascolo, former director of CureVac, and the RNA messenger expert Professor Chantal Pichon. It also features a preface by Dr. Pierre Meulien, former director of the European Union public-private partnership Innovative Medicines Initiative (IMI).
Mrna Therapeutics
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Author : Sarfaraz Niazi
language : en
Publisher: CRC Press
Release Date : 2023
Mrna Therapeutics written by Sarfaraz Niazi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with categories.
"This book is the most comprehensive and complete treatise on nucleic acid therapeutic products, including mRNA vaccines, their manufacturing, formulations, and testing for safety and efficacy testing. Details include cGMP-compliant manufacturing and regulatory filing steps. A new concept of "biosimilar" mRNA vaccine is presented to secure fast approval of copies of mRNA vaccines. Projections of financial plans to establish RNA manufacturing facilities are provided, along with details of supply chain management. Finally, the future of nucleic acid products in gene therapy and other newer applications is presented, along with a perspective that all new vaccines will be the nucleic acid type that will further provide first-time prevention of autoimmune disorders. It is projected that both big pharma and startups will enter this field, and we can expect significant additions to our drug armamentarium soon"--
Potential Benefits And Limitations Of Mrna Technology For Vaccine Research And Development For Infectious Diseases And Virus Induced Cancers
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2023-12-13
Potential Benefits And Limitations Of Mrna Technology For Vaccine Research And Development For Infectious Diseases And Virus Induced Cancers written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-13 with Medical categories.
Breakthrough
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Author : Stephanie Sammartino McPherson
language : en
Publisher: Twenty-First Century Books (Tm)
Release Date : 2023
Breakthrough written by Stephanie Sammartino McPherson and has been published by Twenty-First Century Books (Tm) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with Young Adult Nonfiction categories.
"Breakthrough chronicles the life, hard work, and accomplishments of Katalin Karikó, one of the pioneering mRNA researchers whose work led to COVID-19 vaccines, depicting her as an inspirational figure for readers interested in science"--
Challenges And Opportunities Of Mrna Vaccines Against Sars Cov 2
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Author : Siguna Mueller
language : en
Publisher: Springer Nature
Release Date : 2023-01-04
Challenges And Opportunities Of Mrna Vaccines Against Sars Cov 2 written by Siguna Mueller and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-04 with Medical categories.
This book offers an analytical look at the much debated risks and benefits of the newly developed COVID-19 mRNA-vaccines. As such, it is one of the first books to give a comprehensive overview of mRNA vaccines against COVID-19 and the only one that addresses this topic from a broad multidisciplinary background. It brings together insights from various underlying disciplines on the challenges of developing and evaluating the most suitable vaccines for mass vaccination programs enrolled throughout the world - focusing on safety and efficacy. This book should not be missing on the shelf of any biomedical researcher, epidemiologist, public health professional or clinical researcher interested in SARS-CoV2 or virology and vaccine development in general.
The Marathon Of The Messenger
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Author : Jérôme Lemonnier
language : en
Publisher: Springer
Release Date : 2023-11-09
The Marathon Of The Messenger written by Jérôme Lemonnier and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-09 with Medical categories.
The Covid-19 pandemic changed the world. Indeed a real race took place worldwide between SARS-CoV-2 on the one hand and researchers on the other – especially those specializing in messenger RNA vaccines. Four years after its emergence, the pandemic is not over, but some decisive battles have been won, thanks to the great success of mRNA vaccines. The Marathon of The Messenger presents the history of these mRNA vaccines, combining a scientific background with historical and economic perspectives. It appears that an important page in the history of these new vaccines was written in Europe, thanks to the crucial work of German and French scientists; this effort began in 1993 and continues to this day. In the face of a prevailing single-mindedness, these researchers pushed through a new therapeutic concept and defined the biotechnological keys that would open the way to the production of therapeutic messenger RNA in the fight against cancer and viral infections. Written for a broad audience and accompanied by humorous cartoons, this book will appeal to anyone looking for scientific and historical answers about mRNA vaccines. Readers will discover not only the technical and scientific knowledge of how these vaccines work, but also the economic levers that were necessary to create this technology. This book has been written in collaboration with Dr. Steve Pascolo, former director of CureVac, and the RNA messenger expert Professor Chantal Pichon. It also features a preface by Dr. Pierre Meulien, former director of the European Union public-private partnership Innovative Medicines Initiative (IMI).