Multi Omics Strategies For Detecting Gene Environment Interactions
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Multi Omics Strategies For Detecting Gene Environment Interactions
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Author : Patrick Deelen
language : en
Publisher: Patrick Deelen
Release Date : 2019-05-06
Multi Omics Strategies For Detecting Gene Environment Interactions written by Patrick Deelen and has been published by Patrick Deelen this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-06 with Science categories.
Our DNA, 3 billion letters long, is the blueprint of life. People differ from each other in around 1% of these letters. However, it is largely unknown which of these differences cause disease, nor how exactly changes in DNA ultimately lead to disease. In my PhD research I contributed to the detection of these genetic risk factors and studied how these DNA changes actually disrupt the correct functioning of cells. Using the "Genome of the Netherlands" project results, in which the BBMRI-NL consortium fully mapped the DNA of 250 Dutch families, I was able to improve genetic research in other groups of people and thereby better detect genetic risk factors. I then looked at how these DNA changes disrupt individual cells in a large number of people participating in various Dutch bio-banks such as Lifelines. By looking at DNA, RNA, epigenetics and proteins at the same time, I was able to discover many genetic risk factors, which biological processes they disrupt, and which ones offer starting points for the development of new medicines that can repair these disrupted processes. In addition, through the large-scale re-use of RNA data, I was able to map how many genes relate together and to disease. With these big data analyses, I subsequently developed a new algorithm that is now being used to make a diagnosis more quickly in people with a serious illness. With my PhD research, I contributed to the immediate improvement of patient care and collected new knowledge that could help in the longer term with the development of new medicines.
Applications Of Multi Omics
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Author : Richard Skiba
language : en
Publisher: After Midnight Publishing
Release Date : 2025-02-19
Applications Of Multi Omics written by Richard Skiba and has been published by After Midnight Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-19 with Medical categories.
In the era of big data and personalized medicine, Applications of Multi-Omics serves as a comprehensive guide to integrating biological data across genomics, transcriptomics, proteomics, metabolomics, and epigenomics. This book explores how multi-omics technologies provide a holistic view of biological systems, transforming our understanding of human health, disease mechanisms, drug development, and environmental science. Written for researchers, healthcare professionals, and students in life sciences, this book breaks down complex concepts into accessible insights, covering key methodologies, computational approaches, and real-world applications. From precision medicine and biomarker discovery to AI-driven data integration and ethical considerations, Applications of Multi-Omics provides a deep dive into how multi-layered biological data is revolutionizing biomedical research and healthcare. Whether you are an academic researcher seeking to integrate multi-omics in your studies, a clinician exploring omics-driven diagnostics, or a data scientist working at the intersection of AI and life sciences, this book is an essential resource. It highlights emerging trends, challenges, and future directions in multi-omics, paving the way for groundbreaking discoveries in personalized medicine, biotechnology, and agricultural research. Join the multi-omics revolution and uncover the intricate biological networks shaping the future of science and medicine.
Genetics And Biotechnology In Animal Breeding
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Author : Sameer Sabri Kadim
language : en
Publisher: RK Publication
Release Date : 2025-03-10
Genetics And Biotechnology In Animal Breeding written by Sameer Sabri Kadim and has been published by RK Publication this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-10 with Medical categories.
Genetics and Biotechnology in Animal Breeding the principles of genetic inheritance and the application of modern biotechnological tools in improving livestock productivity and sustainability. Topics such as selective breeding, genetic engineering, molecular markers, and reproductive technologies, this book provides a comprehensive understanding of how genetics and biotechnology shape animal breeding programs. It examines ethical considerations, advancements in genome editing, and the impact of biotechnology on food security and conservation. Ideal for students, researchers, and professionals in animal science, this bridges traditional breeding techniques with cutting-edge innovations for the future of livestock improvement.
Neuroscientific Methods In Practice
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Author : K. Jayasankara Reddy
language : en
Publisher: Taylor & Francis
Release Date : 2025-08-08
Neuroscientific Methods In Practice written by K. Jayasankara Reddy and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-08-08 with Psychology categories.
This book presents an in-depth exploration of the convergence of neuroscience with clinical psychology, clinical neuropsychology, and forensic psychology, examining advanced methodologies, practical applications, and real-world case studies. K. Jayasankara Reddy provides a thorough examination of state-of-the-art neuroscientific methods and the revolutionary effects on both diagnosis and forensic inquiry. Reddy highlights the transformative impact of neuroimaging, neurophysiology, neuroelectrophysiology, and genetic analysis on our comprehension of brain function and behavior, using compelling case examples and empirical evidence. This book not only discusses methods but also critically examines ethical difficulties, merits, and challenges of the techniques, as well as the legal ramifications that may arise from the use of neuroscientific evidence in clinical and forensic settings. This book also highlights the need for a sophisticated comprehension of privacy issues, patient self-governance, and the use of neurobiological information within legal structures. Overall, it provides readers with the tools to negotiate complicated ethical landscapes while responsibly utilizing neuroscientific discoveries, advocating for a balanced approach that combines scientific rigor and ethical responsibility. This volume is an important resource for students, researchers, and practitioners of clinical neuropsychology, forensic psychology, and neuroscience.
Multi Omics In Biomedical Sciences And Environmental Sustainability
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Author : Minu Kesheri
language : en
Publisher: Springer Nature
Release Date : 2025-06-25
Multi Omics In Biomedical Sciences And Environmental Sustainability written by Minu Kesheri and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-25 with Medical categories.
This book offers a comprehensive exploration of the cutting-edge multi-omics technologies that are revolutionizing research across biomedical sciences and environmental sustainability. It addresses the urgent need for interdisciplinary research by integrating multi-omics approaches with bioinformatics and artificial intelligence. The book explores evolution of traditional omics technologies into comprehensive multi-omics strategies that synergize data output through advanced computational tools. It covers diverse topics such as health and disease mechanisms, drug discovery innovations, COVID-19 responses, cancer treatment personalization, neuroscience insights into brain disorders, cyanobacterial natural compounds' potential for biofuel production, lichen symbiosis studies, and more. This volume integrates genomics, proteomics, metabolomics, and more with bioinformatics, machine learning, and artificial intelligence to address complex challenges in health and the environment. With contributions from renowned scholars worldwide, this book illuminates recent advances through illustrative figures and case studies that enhance understanding of complex pathways while bioinformatics strategies streamline research outcomes. This book is a must-read for researchers, academics, and professionals in life sciences, biomedical fields, and environmental studies, interested in advancing their knowledge of multi-omics applications. It is also beneficial for scientists involved in drug design or biotechnological innovations related to environmental sustainability.
Microbial Bioremediation And Multiomics Technologies For Sustainable Development
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Author : Fuad Ameen
language : en
Publisher: Royal Society of Chemistry
Release Date : 2024-08-02
Microbial Bioremediation And Multiomics Technologies For Sustainable Development written by Fuad Ameen and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-02 with Science categories.
The steadily increasing presence of both natural and anthropogenic pollutants in our environment poses a considerable challenge, given the recalcitrance of many of these pollutants. Microbial bioremediation presents a promising and sustainable strategy that harnesses a diverse array of microorganisms, operating either concurrently or sequentially, to eliminate or mitigate the presence of pollutants within the environment. Recent years have witnessed the application of multiomics techniques to the study of biodegradation and bioremediation, yielding an abundance of novel data that enrich our comprehension of pivotal pathways and offer fresh perspectives on the adaptability of organisms amidst shifting environmental conditions. This book brings together recent progress in microbial bioremediation, emphasizing the emerging field of multiomics technologies. It serves as a valuable reference for microbiologists exploring multiomics applications and environmental scientists seeking innovative remediation solutions.
Principles Of Gender Specific Medicine
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Author : Marianne Legato J
language : en
Publisher: Academic Press
Release Date : 2023-04-03
Principles Of Gender Specific Medicine written by Marianne Legato J and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-03 with Technology & Engineering categories.
Awarded with the 2018 Prose Award in Clinical Medicine, the third edition of Principles of Gender-Specific Medicine explored and described exciting new areas in biomedicine that integrated technology into the treatment of disease and the augmentation of human function. Novel topics such as the sex-specific aspects of space medicine, the development and the use of genderized robots and a discussion of cyborgs were included in the third edition, providing a preview of the expanding world of sex-specific physiology and therapeutics. This Fourth Edition is a continuation of the mission to trace the relevance of biological sex to normal function and to the experience of disease in humans.We are now twenty years into the postgenomic era. The investigation of how the genome produces the phenome has led to fascinating insights as well as yet unanswered questions. Principles of Gender-Specific Medicine, Fourth Edition, has a central theme: discuss advances in understanding the role of epigenetics in regulating gene expression in a dynamic, sex-specific way during human life. It explores the protean role of epigenetics in human physiology, the relevance of environmental experience to human function, the therapeutic promise of cutting-edge methodologies like gene manipulation, the preparation of humans for space travel, the use of artificial intelligence in detection and therapeutic decisions concerning disease states, the possibilities for technological support of not only compromised individuals but of the augmentation of human function, and an analysis of the benefits, limitations and issues that surround our current expectations of personalized medicine. - Covers the most important developments in biomedical research in the past decade, with a thoughtful analysis of how they impact patient care - Discusses the feasibility and usefulness of personalized medicine, the limits and promise of genetic editing, the basis for variation in sexual identity and how artificial intelligence and technology will affect basic human function as well as correcting disability - Promotes and facilitates discussions about the ethics and governance issues that surround much of what science is now able to do at the most basic levels of human's physiology
Toxicology For The Health And Pharmaceutical Sciences
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Author : Antonio Peña-Fernández
language : en
Publisher: CRC Press
Release Date : 2021-12-21
Toxicology For The Health And Pharmaceutical Sciences written by Antonio Peña-Fernández and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-21 with Medical categories.
There is an increasing need for knowledge of toxicology to safeguard the use of chemicals in industry and in the public and private sectors. The study of toxicology is becoming increasingly relevant in human health sciences, as future health and clinical professionals will be pivotal in addressing and managing emerging chemical threats and hazards related to modern anthropogenic activities and technological development. Comprising a series of chapters from leading toxicology, pharmacy and public health academics and experts across Europe, the United States and beyond, Toxicology for the Health and Pharmaceutical Sciences provides a concise yet comprehensive volume that can be used as a relevant textbook on toxicology for the clinical, healthcare, educational and professional sectors. Key Features: Includes cutting edge information regarding the very lastest environmental threats to public health Provides a detailed case study based on a real-world scenario that allows the reader to practice human health risk assessment Describes innovative guidance and tools to respond to chemical incidents and attacks, which enables the reader to tailor an effective protection and remediation response This book covers the fundamentals and recent developments in toxicology, to respond to local and global chemical, pharmaceutical and environmental threats. Thus, this volume has chapters specifically designed to support the understanding of the most current toxicology-related subjects for any undergraduate/postgraduate health programs as well as aid the delivery of continuing professional development training on up-to-date topics in toxicology for current practicing health professionals wishing to improve their background knowledge in toxicology. The book is also vital reading and reference for policy makers and others that influence and set regulations that have an impact on the environment and human health.
Statistical Approaches In Omics Data Association Studies
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Author : Qi Yan
language : en
Publisher: Frontiers Media SA
Release Date : 2022-06-07
Statistical Approaches In Omics Data Association Studies written by Qi Yan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-07 with Science categories.
Applied Genetics And Biotechnology In Environmental Engineering Challenges And Opportunities In Coastal Regions
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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date :
Applied Genetics And Biotechnology In Environmental Engineering Challenges And Opportunities In Coastal Regions written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on with Science categories.
The integration of genetics and biotechnology into environmental engineering heralds a new era of precision and sustainability in addressing the multifaceted challenges of coastal regions. These zones, characterized by dynamic ecological interfaces, present unique environmental pressures exacerbated by human activity and climate change. Harnessing molecular and biotechnological innovations offers unprecedented avenues for restoring ecosystem functions, enhancing resource management, and mitigating anthropogenic impacts. This work seeks to elucidate the state-of-the-art technologies and scientific principles underlying the application of genetic tools and biotechnological systems within coastal environmental engineering frameworks. By bridging foundational genetics with applied environmental strategies, it provides a comprehensive resource for researchers, practitioners, and policy-makers navigating the complex nexus of biology, technology, and ecosystem management. The text emphasizes advanced methodologies such as genome editing, synthetic biology, microbial consortia engineering, and omics-driven ecological analysis, underscoring their transformative potential for bioremediation, sustainable aquaculture, and renewable energy generation. It also examines how these approaches can be tailored to the intricate biogeochemical and hydrodynamic conditions unique to coastal ecosystems. A recurring theme throughout is the integration of multidisciplinary perspectives — combining molecular biology, environmental engineering, ecological modeling, and socio-technical considerations. This holistic approach is essential for designing interventions that are not only scientifically robust but also socially responsible and environmentally ethical. Moreover, the work acknowledges the challenges posed by genetic risk assessment, public perception, regulatory frameworks, and the need for stakeholder engagement. These socio-ecological dimensions are critical to the responsible advancement and deployment of biotechnology in sensitive coastal environments. Ultimately, this text aspires to catalyze innovation and informed discourse by equipping the scientific and engineering community with the knowledge required to harness genetics and biotechnology for resilient, adaptive, and sustainable coastal management solutions.