Multicomponent Synthesis
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Multicomponent Reactions In Organic Synthesis
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Author : Jieping Zhu
language : en
Publisher: John Wiley & Sons
Release Date : 2015-02-09
Multicomponent Reactions In Organic Synthesis written by Jieping Zhu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-09 with Science categories.
Comprehensive and up-to-date, this book focuses on the latest advances in the field, such as newly developed techniques, more environmentally benign processes, broadened scopes, and completely novel MCRs. In addition to carbene-promoted MCRs and frequently applied metal-catalyzed MCRs, it also covers recently developed catalytic enantioselective variants as well as MCR in drug discovery and for the synthesis of heterocyclic molecules and macrocycles. Edited by the leading experts and with a list of authors reading like a "who's who" in multicomponent reaction chemistry, this is definitely a must-have for every synthetic organic chemist as well as medicinal chemists working in academia and pharmaceutical companies.
Multicomponent Synthesis
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Author : Basudeb Basu
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2023-12-31
Multicomponent Synthesis written by Basudeb Basu and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-31 with Science categories.
Multicomponent Reactions
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Author : Raquel P. Herrera
language : en
Publisher: John Wiley & Sons
Release Date : 2015-04-01
Multicomponent Reactions written by Raquel P. Herrera and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-01 with Science categories.
Addressing a dynamic aspect of organic chemistry, this bookdescribes synthetic strategies and applications for multicomponentreactions – including key routes for synthesizing complexmolecules. • Illustrates the crucial role and theimportant utility of multicomponent reactions (MCRs) to organicsyntheses • Compiles novel and efficient syntheticmulticomponent procedures to give readers a complete picture ofthis class of organic reactions • Helps readers to design efficient andpractical transformations using multicomponent reactionstrategies • Describes reaction background,applications to synthesize complex molecules and drugs, andreaction mechanisms
Synthesis Of Heterocycles Via Multicomponent Reactions I
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Author : Romano V. A. Orru
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-05-12
Synthesis Of Heterocycles Via Multicomponent Reactions I written by Romano V. A. Orru and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-12 with Science categories.
Contents: L. Banfi ∙ A. Basso ∙ R. Riva: Synthesis of Heterocycles Through Classical Ugi and Passerini Reactions Followed by Secondary Transformations Involving One or Two Additional Functional Groups.- V.A. Chebanov ∙ K. A. Gura ∙ S.M. Desenko: Aminoazoles as Key Reagents in Multicomponent Heterocyclizations.- Y. Huang ∙ K. Khoury ∙ A. Dömling: Piperazine Scaffolds by Multicomponent 3 Reactions: The Piperazine Space 4 in MCR Chemistry 5 Deep MCR Piperazine Space.- N. Elders ∙ E. Ruijter ∙ V.G. Nenajdenko ∙ R.V.A. Orru: α-Acidic Isocyanides in Multicomponent Chemistry.- A. Cukalovic ∙ J.-C.M.R. Monbaliu ∙ C.V. Stevens: Microreactor Technology as an Efficient Tool for Multicomponent Reactions.- L.A. Wessjohann ∙ C.R.B. Rhoden ∙ D.G. Rivera ∙ O. Eichler Vercillo: Cyclic Peptidomimetics and Pseudopeptides from Multicomponent Reactions.- M. del Mar Sanchez Duque ∙ C. Allais ∙ N. Isambert ∙ T. Constantieux ∙ J. Rodriguez: ß-Diketo Building Blocks for MCRs-Based Syntheses of Heterocycles
Synthesis Of Heterocycles Via Multicomponent Reactions Ii
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Author : Romano V. A. Orru
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-05
Synthesis Of Heterocycles Via Multicomponent Reactions Ii written by Romano V. A. Orru and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-05 with Science categories.
Géraldine Masson, Luc Neuville ∙ Carine Bughin ∙ Aude Fayol ∙ Jieping Zhu Multicomponent Syntheses of Macrocycles Thomas J.J. Müller Palladium-Copper Catalyzed Alkyne Activation as an Entry to Multicomponent Syntheses of Heterocycles Rachel Scheffelaar ∙ Eelco Ruijter ∙ Romano V.A. Orru Multicomponent Reaction Design Strategies: Towards Scaffold and Stereochemical Diversity Nicola Kielland ∙ Rodolfo Lavilla Recent Developments in Reissert-Type Multicomponent Reactions Jitender B. Bariwal ∙ Jalpa C. Trivedi ∙ Erik V. Van der Eycken Microwave Irradiation and Multicomponent Reactions Irini Akritopoulou-Zanze ∙ Stevan W. Djuric Applications of MCR-Derived Heterocycles in Drug Discovery
Multicomponent Reactions
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Author : Jieping Zhu
language : en
Publisher: John Wiley & Sons
Release Date : 2006-03-06
Multicomponent Reactions written by Jieping Zhu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Science categories.
In the very first book on this hot topic, the expert editors andauthors present a comprehensive overview of these elegantreactions. From the contents: Organoboron compounds Free-radical mediated multicomponent coupling reactions Applications in drug discovery Metal catalyzed reactions Total synthesis of natural products Asymmetric isocyanide-based reactions The Biginelli reaction Asymmetric isocyanide-based reactions The Domino-Knoevenagel-Hetero-Diels-Alder Reaction and relatedtransformations Catalytic asymmetric reactions Algorithm based methods for discovering novel reactions Post-condensation modifications of the Passerini and Ugireactions An essential reference for organic and catalytic chemists, andthose working in organometallics both in academia and industry.
Multicomponent Reactions Towards Heterocycles
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Author : Erik Van der Eycken
language : en
Publisher: John Wiley & Sons
Release Date : 2022-03-21
Multicomponent Reactions Towards Heterocycles written by Erik Van der Eycken and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-21 with Science categories.
Presents a wide-ranging overview of essential topics and recent advances in MCR chemistry Heterocycles are a central component in natural product chemistry, pharmaceuticals, agrochemicals, and material science. New synthetic methodologies integrating the sequencing of multicomponent reactions (MCRs) are today being used for the rapid synthesis of diversified heterocycles in just one step. Multicomponent Reactions towards Heterocycles presents an up-to-date summary MCR chemistry with a focus on the conjugation between modern synthetic methodologies and MCRs. Featuring contributions by leaders in the field, this comprehensive resource highlights applications of MCRs in natural products and intermediate synthesis, discusses current trends and future prospects in MCR chemistry, outlines novel multicomponent procedures, and more. The authors provide the practical information required for designing new reaction strategies and mechanisms, covering topics including MCR-based green synthetic methods, cyclization and cycloaddition reactions, heterocycle multicomponent syntheses in a continuous flow, catalytic alkynoyl generation, MCR synthesis of saturated heterocycles, and C–H functionalization and multicomponent reactions. Provides a thorough overview of heterocycles as input in multicomponent reactions Discusses recent advances in the field of MCR chemistry and progress in the synthesis and functionalization of heterocycles Demonstrates the use of MCRs to simplify synthetic design and achieve complexity and diversity in novel bioactive molecules Highlights examples of multicomponent polymerizations, target-oriented synthesis, and applications of MCR in medicinal chemistry Explains the methodology of using on-resin MCRs to produce heterocycle compounds Illustrating the key role of MCRs towards heterocycles in natural product synthesis, drug discovery, organic synthesis, and other applications, Multicomponent Reactions towards Heterocycles is required reading for synthetic chemists in academia and industry alike.
Multicomponent Reactions
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Author : K.L. Ameta, Ph.D.
language : en
Publisher: CRC Press
Release Date : 2017-09-20
Multicomponent Reactions written by K.L. Ameta, Ph.D. and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-20 with Medical categories.
This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.
Synthesis Of Heterocycles Via Multicomponent Reactions Ii
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Author :
language : en
Publisher:
Release Date : 2010
Synthesis Of Heterocycles Via Multicomponent Reactions Ii written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Chemical reactions categories.
Géraldine Masson, Luc Neuville ∙ Carine Bughin ∙ Aude Fayol ∙ Jieping Zhu Multicomponent Syntheses of Macrocycles Thomas J.J. Müller Palladium-Copper Catalyzed Alkyne Activation as an Entry to Multicomponent Syntheses of Heterocycles Rachel Scheffelaar ∙ Eelco Ruijter ∙ Romano V.A. Orru Multicomponent Reaction Design Strategies: Towards Scaffold and Stereochemical Diversity Nicola Kielland ∙ Rodolfo Lavilla Recent Developments in Reissert-Type Multicomponent Reactions Jitender B. Bariwal ∙ Jalpa C. Trivedi ∙ Erik V. Van der Eycken Microwave Irradiation and Multicomponent Reactions Irini Akritopoulou-Zanze ∙ Stevan W. Djuric Applications of MCR-Derived Heterocycles in Drug Discovery.
Pot Atom And Step Economy Pase Synthesis
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Author : Wei Zhang
language : en
Publisher: Springer
Release Date : 2019-08-01
Pot Atom And Step Economy Pase Synthesis written by Wei Zhang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-01 with Science categories.
This book emphasizes the atom economy aspect of multicomponent reactions. It describes how this methodology has been applied to several named reactions. Among the “twelve principles of green chemistry”, atom economy addresses ‘synthetic efficiency’. A multicomponent reaction can be defined as an energy, cost, and time efficient method for organic synthesis. Instead of making one or two bonds in a chemical transformation, multicomponent reactions generate several chemical bonds in a single operation. This book presents a series of detailed reaction mechanisms that beautifully illustrate this principle. Multicomponent reactions are widely applied to the preparation of complex and diverse molecular structures in academic and industrial research laboratories. As such, this book is targeted at researchers involved in green organic chemistry.