Multimodal Optical Diagnostics Of Cancer
DOWNLOAD
Download Multimodal Optical Diagnostics Of Cancer PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Multimodal Optical Diagnostics Of Cancer book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Multimodal Optical Diagnostics Of Cancer
DOWNLOAD
Author : Valery V. Tuchin
language : en
Publisher: Springer Nature
Release Date : 2020-10-23
Multimodal Optical Diagnostics Of Cancer written by Valery V. Tuchin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-23 with Medical categories.
This book provides an in-depth description and discussion of different multi-modal diagnostic techniques for cancer detection and treatment using exact optical methods, their comparison, and combination. Coverage includes detailed descriptions of modern state of design for novel methods of optical non-invasive cancer diagnostics; multi-modal methods for earlier cancer diagnostic enhancing the probability of effective cancer treatment; modern clinical trials with novel methods of clinical cancer diagnostics; medical and technical aspects of clinical cancer diagnostics, and long-term monitoring. Biomedical engineers, cancer researchers, and scientists will find the book to be an invaluable resource. Introduces optical imaging strategies; Focuses on multimodal optical diagnostics as a fundamental approach; Discusses novel methods of optical non-invasive cancer diagnostics.
Optical Spectroscopy And Imaging For Cancer Diagnostics Fundamentals Progress And Challenges
DOWNLOAD
Author : Noureddine Melikechi
language : en
Publisher: World Scientific
Release Date : 2023-01-06
Optical Spectroscopy And Imaging For Cancer Diagnostics Fundamentals Progress And Challenges written by Noureddine Melikechi and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-06 with Technology & Engineering categories.
This is an interdisciplinary book that presents the applications of novel laser spectroscopy and imaging techniques for the detection of cancers recently developed by some of the world's most renown researchers. The book consists of three parts and a total of 16 chapters. Each chapter is written by leading experts who are actively seeking to develop novel spectroscopic and analytical methods for cancer detection and diagnosis.In Part I, the authors present fundamentals on optics, atoms and molecules, biophysics, cancer and machine learning. These chapters are intended for those who are not experts in the field but wish to learn about fundamentals' aspects of some of the key topics that are addressed in this book. Particular attention has been given to providing key references for those who wish to go further into the fundamental aspects of atoms and molecules, light-matter interaction, optical instrumentation, machine learning and cancer.In Part II, the authors present key applications of various laser spectroscopic methods in cancer diagnosis. They have provided recent progress in cancer diagnostics obtained by combining laser spectroscopy and machine learning for the analysis of the spectra acquired from biomedical tissues and biofluids.In Part III, the authors present chapters that discuss key developments in the applications of various laser imaging techniques for cancer detection.This is one of the few books that addresses cancer detection and diagnosis using laser spectroscopic and imaging tools with an eye on providing the reader the scientific tools, including machine learning ones.
Optical Detection Of Cancer
DOWNLOAD
Author : Arlen D. Meyers
language : en
Publisher: World Scientific
Release Date : 2012
Optical Detection Of Cancer written by Arlen D. Meyers and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
Ch. 1. The optical detection of cancer: an introduction / Toby Steele and Arlen Meyers -- ch. 2. Optical coherence tomography in oral cancer / Shahareh Sabet and Petra Wilder-Smith -- ch. 3. Optical coherence tomography in laryngeal cancer / Marcel Kraft and Christoph Arens -- ch. 4. Fluorescence imaging of the upper aerodigestive tract / Christian Stephan Betz, Andreas Leunig and Christoph Arens -- ch. 5. Photodynamic diagnosis and photodynamic therapy techniques / Zheng Huang -- ch. 6. OCT detection of lung cancer / S. Murgu and M. Brenner -- ch. 7. Diffuse optical spectroscopy and imaging in breast cancer / Albert E. Cerussi and Bruce J. Tromberg -- ch. 8. OCT for skin cancer / Gordon McKenzie and Adam Meekings
Multimodal Multispectral Optical Endoscopic Imaging For Biomedical Applications
DOWNLOAD
Author :
language : en
Publisher:
Release Date : 2011
Multimodal Multispectral Optical Endoscopic Imaging For Biomedical Applications written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.
Optical Coherence Tomography And Targeted Multi Modal Protein Microspheres For Cancer Imaging
DOWNLOAD
Author :
language : en
Publisher:
Release Date : 2015
Optical Coherence Tomography And Targeted Multi Modal Protein Microspheres For Cancer Imaging written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
Evaluation And Development Of Non Linear Multimodal Imaging Towards Routine Clinical Cancer Diagnostics
DOWNLOAD
Author :
language : de
Publisher:
Release Date : 2015
Evaluation And Development Of Non Linear Multimodal Imaging Towards Routine Clinical Cancer Diagnostics written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
A Multimodal Breast Cancer Imaging System Using Coregistered Dynamic Diffuse Optical Tomography And Digital Breast Tomosynthesis
DOWNLOAD
Author : Bernhard B. Zimmermann
language : en
Publisher:
Release Date : 2017
A Multimodal Breast Cancer Imaging System Using Coregistered Dynamic Diffuse Optical Tomography And Digital Breast Tomosynthesis written by Bernhard B. Zimmermann and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
Diffuse optical tomography (DOT) is an emerging noninvasive functional imaging method for breast cancer diagnosis and neoadjuvant chemotherapy monitoring. In particular, the multimodal approach of combining DOT with x-ray digital breast tomosynthesis (DBT) is especially synergistic as DBT prior information can be used to enhance the DOT reconstruction. DOT, in turn, provides a functional information overlay onto the mammographic images, increasing sensitivity and specificity to cancer pathology. We describe a dynamic DOT apparatus designed for tight integration with commercial DBT scanners and providing a fast (1 Hz+) image acquisition rate to enable tracking of hemodynamic changes induced by the mammographic breast compression. The most significant advance enabling fast acquisition was the design and construction of a direct analog-to-digital conversion frequency-domain near-infrared spectroscopy (FD-NIRS) component. It achieves simultaneous dual wavelength operation at 685 nm and 830 nm by concurrent 67.5 MHz and 75 MHz frequency modulation of each laser source, respectively, followed by digitization using a high-speed analog to digital converter and real-time hybrid FPGA-assisted demodulation by discrete Fourier transform (DFT). The overall DOT system integrates 96 CW-NIRS and 24 FD-NIRS source locations, as well as 32 CW-NIRS and 20 FD-NIRS detection locations into low-profile plates that mate to the DBT compression paddle and x-ray detector cover, respectively. The plates and the embedded optical fibers are made of plastic to minimize x-ray absorption and thus allow true simultaneous acquisition of the DBT image. We first characterize each major system component individually, and then demonstrate overall performance using static and dynamic tissue-like phantoms, as well as in vivo images acquired from the pool of patients recalled for breast biopsies at the Massachusetts General Hospital Breast Imaging Division.
Morpho Molecular Ex Vivo Detection And Grading Of Non Muscle Invasive Bladder Cancer Using Forward Imaging Probe Based Multimodal Optical Coherence Tomography And Raman Spectroscopy
DOWNLOAD
Author : Fabian Placzek
language : en
Publisher:
Release Date : 2020
Morpho Molecular Ex Vivo Detection And Grading Of Non Muscle Invasive Bladder Cancer Using Forward Imaging Probe Based Multimodal Optical Coherence Tomography And Raman Spectroscopy written by Fabian Placzek and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
Abstract: Non-muscle-invasive bladder cancer affects millions of people worldwide, resulting in significant discomfort to the patient and potential death. Today, cystoscopy is the gold standard for bladder cancer assessment, using white light endoscopy to detect tumor suspected lesion areas, followed by resection of these areas and subsequent histopathological evaluation. Not only does the pathological examination take days, but due to the invasive nature, the performed biopsy can result in significant harm to the patient. Nowadays, optical modalities, such as optical coherence tomography (OCT) and Raman spectroscopy (RS), have proven to detect cancer in real time and can provide more detailed clinical information of a lesion, e.g. its penetration depth (stage) and the differentiation of the cells (grade). In this paper, we present an ex vivo study performed with a combined piezoelectric tube-based OCT-probe and fiber optic RS-probe imaging system that allows large field-of-view imaging of bladder biopsies, using both modalities and co-registered visualization, detection and grading of cancerous bladder lesions. In the present study, 119 examined biopsies were characterized, showing that fiber-optic based OCT provides a sensitivity of 78% and a specificity of 69% for the detection of non-muscle-invasive bladder cancer, while RS, on the other hand, provides a sensitivity of 81% and a specificity of 61% for the grading of low- and high-grade tissues. Moreover, the study shows that a piezoelectric tube-based OCT probe can have significant endurance, suitable for future long-lasting in vivo applications. These results also indicate that combined OCT and RS fiber probe-based characterization offers an exciting possibility for label-free and morpho-chemical optical biopsies for bladder cancer diagnostics
Cancer Diagnostics Using Dynamic Near Infrared Optical Imaging And Fluorescent Contrast Agents
DOWNLOAD
Author : Mikhail Gurfinkel
language : en
Publisher:
Release Date : 2006
Cancer Diagnostics Using Dynamic Near Infrared Optical Imaging And Fluorescent Contrast Agents written by Mikhail Gurfinkel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.
A new optical imaging modality has been developed for small animal in vivo imaging of near-infrared fluorescence resulting from fluorescent contrast agents specifically targeted to molecular markers of cancer. The imaging system is comprised of an intensified charge-coupled device (ICCD) for the detection of ultra-low levels of re-emitted fluorescence following the delivery of an expanded beam of excitation light. The design of the ICCD detection system allows for both continuous wave (CW) and frequency-domain modes of operation. Since the accurate acquisition of frequency-domain photon migration (FDPM) data is important for tomographic imaging, the imaging system was also validated using experimentally obtained FDPM measurements of homogenous turbid media and diffusion theory to obtain estimates of the optical properties characteristic of the media. The experiments demonstrated that the absorption and reduced scattering coefficients are determined least accurately when relative measurements of average light intensity I rel [over] DC are employed either alone or in a combination with relative modulation amplitude data I rel [over] AC and/or relative phase shift data [theta] [superscript]rel. However, when FDPM measurements of [theta] [superscript]rel are employed either alone or in combination with I rel [over] AC data, the absorption and reduced scattering coefficients may be found accurate to within 15% and 11%, respectively, of the values obtained from standard single-pixel measurements; a result that suggests that FDPM data obtained from an ICCD detection system may in fact be useful in tomographic imaging. Furthermore, intensified-detection allows for sub-second exposure times, permitting the acquisition of dynamic fluorescence images immediately following administration of the contrast agent. Experimental results demonstrate that when coupled with a suitable pharmacokinetic model describing targeted dye distribution throughout the body, dynamic fluorescence imaging may be used to discriminate spontaneous canine adenocarcinoma from normal mammary tissue. A separate experiment demonstrates that pharmacokinetic analysis of dynamic fluorescence images enables one to estimate the rate constant governing Kaposi's sarcoma tumor uptake of an [alpha subscriptV beta]3 integrin-targeted dye and integrin receptor turnover rate. The rate constant for uptake was calculated to be 0.16-sec−1 while the turnover rate of the integrin receptor was estimated to occur within 24-hours.
Polarization Based Optical Imaging With The Application To Cancer Diagnostics
DOWNLOAD
Author : Gang L. Liu
language : en
Publisher:
Release Date : 2002
Polarization Based Optical Imaging With The Application To Cancer Diagnostics written by Gang L. Liu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Melanoma categories.