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Multiple Isoforms Of Transcription Factor Ap 2 Expressed During Mouse Embryogenesis


Multiple Isoforms Of Transcription Factor Ap 2 Expressed During Mouse Embryogenesis
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Multiple Isoforms Of Transcription Factor Ap 2 Expressed During Mouse Embryogenesis


Multiple Isoforms Of Transcription Factor Ap 2 Expressed During Mouse Embryogenesis
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Author : Pascal Meier
language : en
Publisher:
Release Date : 1996

Multiple Isoforms Of Transcription Factor Ap 2 Expressed During Mouse Embryogenesis written by Pascal Meier and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with categories.


Zsfassung in dt. Sprache.



Multiple Isoform Of Transcription Factor Ap 2 Expressed During Mouse Embryogenesis


Multiple Isoform Of Transcription Factor Ap 2 Expressed During Mouse Embryogenesis
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Author : Pascal Meier
language : en
Publisher:
Release Date : 1996

Multiple Isoform Of Transcription Factor Ap 2 Expressed During Mouse Embryogenesis written by Pascal Meier and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with categories.




Transcriptional Control Of Neural Crest Development


Transcriptional Control Of Neural Crest Development
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Author : Brian Nelms
language : en
Publisher: Biota Publishing
Release Date : 2010-02-01

Transcriptional Control Of Neural Crest Development written by Brian Nelms and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-02-01 with Science categories.


The neural crest is a remarkable embryonic population of cells found only in vertebrates and has the potential to give rise to many different cell types contributing throughout the body. These derivatives range from the mesenchymal bone and cartilage comprising the facial skeleton, to neuronal derivatives of the peripheral sensory and autonomic nervous systems, to melanocytes throughout the body, and to smooth muscle of the great arteries of the heart. For these cells to correctly progress from an unspecifi ed, nonmigratory population to a wide array of dynamic, differentiated cell types—some of which retain stem cell characteristics presumably to replenish these derivatives—requires a complex network of molecular switches to control the gene programs giving these cells their defi ning structural, enzymatic, migratory, and signaling capacities. This review will bring together current knowledge of neural crest-specifi c transcription factors governing these progressions throughout the course of development. A more thorough understanding of the mechanisms of transcriptional control in differentiation will aid in strategies designed to push undifferentiated cells toward a particular lineage, and unraveling these processes will help toward reprogramming cells from a differentiated to a more naive state. Table of Contents: Introduction / AP Genes / bHLH Genes / ETS Genes / Fox Genes / Homeobox Genes / Hox Genes / Lim Genes / Pax Genes / POU Domain Genes / RAR/RXR Genes / Smad Genes / Sox Genes / Zinc Finger Genes / Other Miscellaneous Genes / References / Author Biographies



Biology Of The Mammary Gland


Biology Of The Mammary Gland
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Author : John A. Mol
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11

Biology Of The Mammary Gland written by John A. Mol and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Science categories.


Proceedings of the European Cooperation in the Field of Scientific and Technical Research (COST 825) Symposium on Mammary Gland Biology, held September 16-18, 1999, in Tours, France. It is difficult to overstate the evolutionary and functional significance of mammary tissue in biology. Substantial progress has been made by researchers in various disciplines, particularly over the last fifteen years, towards realizing the potential of this tissue to yield powerful experimental models for morphogenesis and tissue development; for cellular differentiation; for the biosynthesis and secretion of proteins, lipids, small molecules and inorganic salts; and for the coordination and regulation of these processes. More recently, the possibility of exploiting the secretory epithelial cells of mammary tissue as `cell factories' has become a reality and the recombinant production by lactating animals of an increasing number of proteins, valuable both in the pharmaceutical and `nutraceutical' fields, is in progress or under development. Also in this sphere of agricultural production, genetic as well as nutritional technologies are under investigation and exploitation to optimize milk composition for various end-uses - for instance in food process and manufacture. The possibilities of deriving health benefit from the bioactive properties of some of the minor constituents of milk are emerging to counter the highly-publicized negative health impact of excessive consumption of saturated animal fats. In human nutrition and medicine, the mammary gland is both a source of nutrition to the neonate and a potential health threat to the adult female - breast cancer remains the major single cause of female mortality in most developed countries. This volume provides a unique glimpse into our understanding, at the cutting edge of a variety of disciplines, of this versatile and extraordinary tissue, at the birth of the twenty-first century.



Epigenetics And Metabolomics


Epigenetics And Metabolomics
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Author : Paban K. Agrawala
language : en
Publisher: Elsevier
Release Date : 2021-08-25

Epigenetics And Metabolomics written by Paban K. Agrawala and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-25 with Medical categories.


Epigenetics and Metabolomics, a new volume in the Translational Epigenetics series, offers a synthesized discussion of epigenetic control of metabolic activity, and systems-based approaches for better understanding these mechanisms. Over a dozen chapter authors provide an overview of epigenetics in translational medicine and metabolomics techniques, followed by analyses of epigenetic and metabolomic linkage mechanisms likely to result in effective identification of disease biomarkers, as well as new therapies targeting the removal of the inappropriate epigenetic alterations. Epigenetic interventions in cancer, brain damage, and neuroendocrine disease, among other disorders, are discussed in-depth, with an emphasis on exploring next steps for clinical translation and personalized healthcare. Offers a synthesized discussion of epigenetic regulation of metabolic activity and systems-based approaches to power new research Discusses epigenetic control of metabolic pathways and possible therapeutic targets for cancer, neurodegenerative, and neuroendocrine diseases, among others Provides guidance in epigenomics and metabolomic research methodology



The Pigmentary System


The Pigmentary System
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Author : James J. Nordlund
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15

The Pigmentary System written by James J. Nordlund and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Medical categories.


The most comprehensive and integrated book on pigmentation The Pigmentary System, Second Edition, gathers into one convenient, all-inclusive volume a wealth of information about the science of pigmentation and all the common and rare clinical disorders that affect skin color. The two parts, physiology (science) and pathophysiology (clinical disorders), are complementary and annotated so that those reading one part can easily refer to relevant sections in the other. For the clinician interested in common or rare pigment disorders or the principles of teaching about such disorders, this book provides an immediate and complete resource on the biologic bases for these disorders. For the scientist studying the biology of melanocyte function, the book provides a list of disorders that are related to basic biological functions of melanocytes. New features of this Second Edition include: Completely new section on the basic science of pigmentation – explaining the integration of melanocyte functions with other epidermal cells and with various organ systems like the immune system New chapters on pigmentary disorders related to intestinal diseases, the malignant melanocyte, benign proliferations of melanocytes (nevi) and phototherapy with narrow band UV All clinical chapters include the latest genetic findings and advances in therapy More than 400 color images of virtually all clinical disorders The book is ideal for all dermatologists and especially those interested in disorders of pigmentation. It is of particular use for pediatric dermatologists and medical geneticists caring for patients with congenital and genetic pigmentary disorders. This authoritative volume will fill the gap for dermatology training programs that do not have local experts on pigmentation. Basic and cosmetic scientists studying pigmentation and melanocytes will find the science and clinical correlations very useful in showing human significance and relevance to the results of their studies.



Untranslated Gene Regions And Other Non Coding Elements


Untranslated Gene Regions And Other Non Coding Elements
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Author : Lucy W. Barrett
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-26

Untranslated Gene Regions And Other Non Coding Elements written by Lucy W. Barrett and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-26 with Science categories.


There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.​



New Topics In Cancer Research


New Topics In Cancer Research
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Author : Fredrick G. Drabell
language : en
Publisher: Nova Publishers
Release Date : 2006

New Topics In Cancer Research written by Fredrick G. Drabell and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Cancer categories.


Cancer is a group of different diseases (more than 100) characterised by uncontrolled growth and spread of abnormal cells. Cancer can arise in many sites and behave differently depending on its organ of origin. If a cancer spreads (metastasizes), the new tumour bears the same name as the original (primary) tumour. Significant progress has been made in recent years in the battle against cancer and in understanding its underlying biological mechanisms. This research progress has resulted in many experimental treatments and cures which establish hope for wide-spread cures. This book brings together important research from around the world in this frontal field.



Research On Melanoma


Research On Melanoma
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Author : Mandi Murph
language : en
Publisher: BoD – Books on Demand
Release Date : 2011-09-12

Research On Melanoma written by Mandi Murph and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-12 with Medical categories.


The book Research on Melanoma: A Glimpse into Current Directions and Future Trends, is divided into sections to represent the most cutting-edge topics in melanoma from around the world. The emerging epigenetics of disease, novel therapeutics under development and the molecular signaling aberrations are explained in detail. Since there are a number of areas in which unknowns exist surrounding the complex development of melanoma and its response to therapy, this book illuminates and comprehensively discusses such aspects. It is relevant for teaching the novice researcher who wants to initiate projects in melanoma and the more senior researcher seeking to polish their existing knowledge in this area. Many chapters include visuals and illustrations designed to easily guide the reader through the ideas presented.



Trends In Chemotherapy Research


Trends In Chemotherapy Research
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Author : Margaret D. Weber
language : en
Publisher: Nova Publishers
Release Date : 2005

Trends In Chemotherapy Research written by Margaret D. Weber and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Cancer categories.


Cancer is a word that rightly strikes fear into the collective heart of humanity. It is a brutally indiscriminate killer and incurable (to date) disease. Able to infest any part of the body, from the brain to the bones to the lungs and liver, cancer seemingly mocks the inability to eliminate it. Treatment for cancer varies depending on the severity and type of neoplasm the patient has. The most well-known of these responses is chemotherapy, which involves the use of chemicals. In order to stem the spread of a patient's cancer, chemotherapy has the patient undergo a series of doses aimed at killing the cancerous cells. Unfortunately, the chemicals can also destroy healthy cells, particularly those that divide quickly. This action leads to side effects such as hair loss, fatigue, nausea, and anaemia. Even though the treatments may be of an overall benefit in eliminating or slowing cancer, the period of treatment is often an arduous one for the patient. Modern research has led to a virtual new era in chemotherapy with target drugs. This book brings together the latest research results in the fast moving field.