Transcriptional Control Of Neural Crest Development
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Transcriptional Control Of Neural Crest Development
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Author : Brian Nelms
language : en
Publisher: Biota Publishing
Release Date : 2010-02-01
Transcriptional Control Of Neural Crest Development written by Brian Nelms and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-02-01 with Science categories.
The neural crest is a remarkable embryonic population of cells found only in vertebrates and has the potential to give rise to many different cell types contributing throughout the body. These derivatives range from the mesenchymal bone and cartilage comprising the facial skeleton, to neuronal derivatives of the peripheral sensory and autonomic nervous systems, to melanocytes throughout the body, and to smooth muscle of the great arteries of the heart. For these cells to correctly progress from an unspecifi ed, nonmigratory population to a wide array of dynamic, differentiated cell types—some of which retain stem cell characteristics presumably to replenish these derivatives—requires a complex network of molecular switches to control the gene programs giving these cells their defi ning structural, enzymatic, migratory, and signaling capacities. This review will bring together current knowledge of neural crest-specifi c transcription factors governing these progressions throughout the course of development. A more thorough understanding of the mechanisms of transcriptional control in differentiation will aid in strategies designed to push undifferentiated cells toward a particular lineage, and unraveling these processes will help toward reprogramming cells from a differentiated to a more naive state. Table of Contents: Introduction / AP Genes / bHLH Genes / ETS Genes / Fox Genes / Homeobox Genes / Hox Genes / Lim Genes / Pax Genes / POU Domain Genes / RAR/RXR Genes / Smad Genes / Sox Genes / Zinc Finger Genes / Other Miscellaneous Genes / References / Author Biographies
Transcriptional Control Of Neural Crest Development
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Author : Brian L. Nelms
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2010
Transcriptional Control Of Neural Crest Development written by Brian L. Nelms and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Science categories.
The neural crest is a remarkable embryonic population of cells found only in vertebrates and has the potential to give rise to many different cell types contributing throughout the body. These derivatives range from the mesenchymal bone and cartilage comprising the facial skeleton, to neuronal derivatives of the peripheral sensory and autonomic nervous systems, to melanocytes throughout the body, and to smooth muscle of the great arteries of the heart. For these cells to correctly progress from an unspecifi ed, nonmigratory population to a wide array of dynamic, differentiated cell types-some of which retain stem cell characteristics presumably to replenish these derivatives-requires a complex network of molecular switches to control the gene programs giving these cells their defi ning structural, enzymatic, migratory, and signaling capacities. This review will bring together current knowledge of neural crest-specifi c transcription factors governing these progressions throughout the course of development. A more thorough understanding of the mechanisms of transcriptional control in differentiation will aid in strategies designed to push undifferentiated cells toward a particular lineage, and unraveling these processes will help toward reprogramming cells from a differentiated to a more naive state. Table of Contents: Introduction / AP Genes / bHLH Genes / ETS Genes / Fox Genes / Homeobox Genes / Hox Genes / Lim Genes / Pax Genes / POU Domain Genes / RAR/RXR Genes / Smad Genes / Sox Genes / Zinc Finger Genes / Other Miscellaneous Genes / References / Author Biographies
The Neural Crest
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Author : Nicole Le Douarin
language : en
Publisher: Cambridge University Press
Release Date : 1999-11-28
The Neural Crest written by Nicole Le Douarin and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-11-28 with Medical categories.
This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.
Neural Crest Stem Cells
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Author : Maya Sieber-Blum
language : en
Publisher: World Scientific
Release Date : 2012
Neural Crest Stem Cells written by Maya Sieber-Blum and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
Offers readers an understanding of the development of neural crest cells, which is crucial as many birth defects and tumours are of neural crest origin. Delving into stem cells from different locations of the body, this book explores the best possible source of such cells for the use in medical applications.
The Neural Crest In Development And Evolution
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Author : Brian K. Hall
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-14
The Neural Crest In Development And Evolution written by Brian K. Hall and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Science categories.
Knowledge of the development and evolution of the neural crest sheds light on many of the oldest unanswered questions in developmental biology. What is the role of germ layers in early embryogenesis? How does the nervous system develop? How does the vertebrate head arise developmentally and how did it arise evolutionarily? How do growth factors and Hox genes direct cell differenti ation and embryonic patterning? What goes wrong when development is misdi rected by mutations or by exposure of embryos to exogenous agents such as drugs, alcohol, or excess vitamin A? In 1988, I was instrumental in organizing the publication of a facsimile reprint of the classic monograph by Sven Horstadius, The Neural Crest: Its properties and derivatives in the light of experimental research, which was originally pub lished in 1950. Included with the reprint was my analysis of more recent studies of the neural crest and its derivatives. The explosion of interest in and knowledge of the neural crest over the past decade, however, has prompted me to produce this new treatment. Here, as in my 1988 overview, I take a broad approach to the neural crest, dealing with its discovery, its embryological and evolutionary ori gins, its cellular derivatives-in both agnathan and jawed vertebrates or gnathos tomes-and the broad topics of migration and differentiation in normal development. Cells from the neural crest are also associated with many develop mental abnormalities.
Murine Homeobox Gene Control Of Embryonic Patterning And Organogenesis
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Author : Thomas Lufkin
language : en
Publisher: Elsevier
Release Date : 2003-12-03
Murine Homeobox Gene Control Of Embryonic Patterning And Organogenesis written by Thomas Lufkin and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-03 with Science categories.
The first homeobox gene was molecular cloned nearly two decades ago, and since that time tremendous progress has been made in our understanding of the distribution of homeobox genes in the genomes of many animal species and the common functional role the encoded homeodomains play in cell-type specification, morphogenesis and development.The amino acid sequence of the homeodomain, as well as the presence of other conserved protein domains, has allowed the classification of homeodomain-containing proteins (homeoproteins) into over thirty separate families (e.g. Hox, Dlx, Msx, Otx, Hmx, Cdx etc.). In many cases a single gene has been shown to fully direct the morphogenesis and development of a complex tissue, organ or even an entire body segment. Yet how this "master" regulatory ability of homeoproteins functions at the molecular level to a large degree still remains a mystery, in part owing to our limited understanding of the nature of both homeoprotein transcriptional cofactors and even more elusively, the downstream targets of homeoprotein function. In the reviews presented here it is limited primarily to what has been learned in vertebrate systems, principally focusing on the mouse, owing to the strengths of the technical approaches currently existing in murine developmental genetics that are not yet available to the same degree in other vertebrate species. Despite this mammalian predilection, a common thread to each of these reviews is the underlying importance of what has been learned about homeoprotein function in other animal species, particularly arthropods like Drosophila.
Craniofacial Development
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Author : Peter Thorogood
language : en
Publisher:
Release Date : 1988
Craniofacial Development written by Peter Thorogood and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Bones categories.
Biomedical Index To Phs Supported Research
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Author :
language : en
Publisher:
Release Date : 1990
Biomedical Index To Phs Supported Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medicine categories.
Gene Control
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Author : David S. Latchman
language : en
Publisher: Taylor & Francis
Release Date : 2025-02-26
Gene Control written by David S. Latchman and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-26 with Science categories.
The new edition of Gene Control, for the first time, provides extensive coverage on prokaryotic gene regulation, which makes it the only textbook offering a complete and detailed account of gene control for both prokaryotic and eukaryotic organisms. The core objective of this edition is to educate students about the fundamental principles and mechanisms governing gene expression, regulation, and function. To reinforce these ideas, each chapter now includes discussion questions to promote critical thinking. There are also multiple choice questions and animations for students, and a large question bank and figure slides for instructors. The textbook also emphasizes the vital role of scientific experiments and evidence in shaping our current understanding of gene control and provides comprehensive coverage of essential gene expression techniques and methodologies throughout the book. This extensively updated edition of the renowned textbook Gene Control will remain a valuable resource for students, instructors, researchers, and medical professionals exploring various aspects of gene control, ranging from the regulation of genes in infectious diseases to embryonic development across different organisms, from bacteria to humans.