Multiple Sclerosis 2
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Multiple Sclerosis 2
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Author : W. Ian McDonald
language : en
Publisher: Butterworth-Heinemann
Release Date : 2003
Multiple Sclerosis 2 written by W. Ian McDonald and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Medical categories.
"This practical resource encompasses the newest essential information on multiple sclerosis-focusing on those areas where progress has been made in research, bringing about new concepts of patient management"--Back cover.
Multiple Sclerosis
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2001-08-10
Multiple Sclerosis written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-08-10 with Medical categories.
Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.
Primary Progressive Multiple Sclerosis
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Author : Nancy J. Holland
language : en
Publisher: Diamedica
Release Date : 2009-12
Primary Progressive Multiple Sclerosis written by Nancy J. Holland and has been published by Diamedica this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12 with Multiple sclerosis categories.
Primary progressive multiple sclerosis (PPMS) affects approximately 10% of the MS population, and is characterized by a steady decline in function, without relapses. This book is geared to the wide variety of physical and emotional issues of people with PPMS and their families. It explains the nature and characteristics of the disease, as well as comprehensive multidisciplinary management.
Primary Progressive Multiple Sclerosis
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Author : M. Filippi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Primary Progressive Multiple Sclerosis written by M. Filippi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
"Why are there no effective treatments for my condition? Why do researchers exclude patients with primary progressive multiple sclerosis from enrolling in clinical trials? Please let me know if you hear of studies that I might be allowed to enter or treatments that I could try for my condition. " Thus, in recent years, the sad lament of the patient with primary progressive MS (PPMS). This variant, often in the guise of a chronic progressive myelopathy or, less commonly, progressive cerebellar or bulbar dysfunction, usually responds poorly to corticosteroids and rarely seems to benefit to a significant degree from intensive immunosuppressive treatments. In recent years, most randomized clin ical trials have excluded PPMS patients on two counts. Clinical worsening devel ops slowly in PPMS and may not be recognized during the course of a 2-or 3-year trial even in untreated control patients. This factor alone adds to the potential for a type 2 error or, at the very least, inflates the sample size and duration of the trial. In addition, there is mounting evidence that progressive axonal degeneration and neuronal loss (rather than active, recurrent inflammation) may be important components of the pathology in this form of the disease. Although contemporary trials are evaluating whether PPMS patients may benefit from treatment with the ~-interferons and glatiramer acetate, preliminary, uncontrolled clinical experi ence suggests that the results may not be dramatic.
Multiple Sclerosis From Both Sides Of The Desk
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Author : Vincent F. Macaluso, MD
language : en
Publisher: iUniverse
Release Date : 2015-06-02
Multiple Sclerosis From Both Sides Of The Desk written by Vincent F. Macaluso, MD and has been published by iUniverse this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-02 with Medical categories.
“Dr. Macaluso has written the Iliad and the Odyssey of multiple sclerosis while playing the part of Odysseus. Amazing!” Carlo Tornatore, MD, Vice Chairman, Department of Neurology Georgetown University Hospital, Washington, DC Vincent F. Macaluso was in medical school when he got the news: he had multiple sclerosis. He soon learned that almost a half million people in the United States have multiple sclerosis—and millions more worldwide. Many have obvious symptoms, such as trouble with walking, balance, and coordination, but the most insidious aspect of the disease is how it affects the mind. Macaluso shares insights from his vantage point as a doctor and an MS patient, helping his peers understand symptoms they may not grasp and offering wisdom for those who live with the disease. Learn how to • anticipate and overcome problems concentrating; • manage swirling emotions; • understand MS from a neurological standpoint; • preserve and continue to enjoy an active sex life; and • prevent the disease from ruining family life. Laced with humor and filled with diagrams and the author’s own recollections about how he’s kept MS from controlling his life, this account is essential reading for doctors, patients, and anyone who has an MSer in his or her life.
Multiple Sclerosis
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Author : Víctor M. Rivera
language : en
Publisher:
Release Date : 2022
Multiple Sclerosis written by Víctor M. Rivera and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.
The book “Multiple Sclerosis: Diagnosis and Treatment” provides a collection of selected articles published in Biomedicines as part of Volume II addressing current issues on this major inflammatory demyelinating neurological disorder. The articles describe recent advances and discoveries in the molecular and cell microenvironment contributing to neuro-inflammation in the brain and spinal cord. The role of the neurofilaments light chain as a serological biomarker of axonal and neuronal degeneration of the CNS is presented not just as a sensitive diagnostic tool, but also as an indicator of treatment responses. The new generation of therapeutic molecules belonging to the sphingosine-1-phosphate class are discussed, and their potential as disease-modifying treatment is considered. Investigations into the intimate molecular mechanisms of highly active MS, disclosed clinically and by MRI, are discussed by researchers proposing that the expression of RNAs in peripheral blood cells is a biomarker of highly active disease. The book also addresses important clinical and epidemiological aspects of pediatric MS and that in multi-ethnic cohorts.
Multiple Sclerosis
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Author : Ian S. Zagon
language : en
Publisher:
Release Date : 2017
Multiple Sclerosis written by Ian S. Zagon and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
The Molecular And Clinical Pathology Of Neurodegenerative Disease
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Author : Patrick A. Lewis
language : en
Publisher: Academic Press
Release Date : 2018-11-16
The Molecular And Clinical Pathology Of Neurodegenerative Disease written by Patrick A. Lewis and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-16 with Science categories.
The Molecular and Clinical Pathology of Neurodegenerative Disease brings together in one volume our current understanding of the molecular basis of neurodegeneration in humans, targeted at neuroscientists and graduate students in neuroscience, and the biomedical and biological sciences. Bringing together up-to-date molecular biology data with clinical evidence, this book sheds a light on common molecular mechanisms that underlie many different neurodegenerative diseases and addresses the molecular pathologies in each. The combined research and clinical background of the authors provides a unique perspective in relating clinical experiences with the molecular understanding needed to examine these diseases and is a must-read for anyone who wants to learn more about neurodegeneration. Provides an up-to-date summary of neurodegeneration at a molecular, cellular, and tissue level for the most common human disorders Describes the clinical background and underlying molecular processes for Alzheimer’s disease, Parkinson’s, Prion, Motor Neuron, Huntington’s, and Multiple Sclerosis Highlights the state-of-the-art treatment options for each disorder Details examples of relevant cutting edge experimental systems, including genome editing and human pluripotent stem cell-derived neuronal models
Neuroimmune Diseases
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Author : Hiroshi Mitoma
language : en
Publisher: Springer
Release Date : 2019-08-13
Neuroimmune Diseases written by Hiroshi Mitoma and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-13 with Medical categories.
A translational overview of neuroimmune diseases for neuroscientists and clinicians that clarifies the pathological mechanisms underlying neuroimmune diseases and builds a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The book will be invaluable for use in clinical practice of neuroimmune diseases
Understanding Multiple Sclerosis
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Author : Melissa Stauffer
language : en
Publisher: Univ. Press of Mississippi
Release Date : 2009-09-18
Understanding Multiple Sclerosis written by Melissa Stauffer and has been published by Univ. Press of Mississippi this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-18 with Health & Fitness categories.
Two-and-a-half million people world-wide and 400,000 Americans suffer from the chronic disease multiple sclerosis. Understanding Multiple Sclerosis presents both general information about MS and valuable, specific advice. Who gets MS? What are its symptoms? What are its effects on the bodies and minds of people afflicted? How does one plan for the future after a diagnosis? From basic biology to new advances in treatment, Understanding Multiple Sclerosis covers the topics most relevant to people with MS and to their families and friends. Chapters provide an introduction to genetic, demographic, and geographic factors; basic biology of MS, with descriptions of both the central nervous system and the immune system; characteristic symptoms of MS; diagnostic criteria and different types of MS treatments, over-the-counter medications, and alternative medicines; lifestyle adjustments and coping strategies, along with advice on long-term health insurance and financial planning; and current and ongoing MS research and advances.