Multiscale Modeling Of Cardiac Electrophysiology Adaptation To Atrial And Ventricular Rhythm Disorders And Pharmacological Treatment
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Multiscale Modeling Of Cardiac Electrophysiology Adaptation To Atrial And Ventricular Rhythm Disorders And Pharmacological Treatment
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Author : Mathias Wilhelms
language : en
Publisher: KIT Scientific Publishing
Release Date : 2014-05-22
Multiscale Modeling Of Cardiac Electrophysiology Adaptation To Atrial And Ventricular Rhythm Disorders And Pharmacological Treatment written by Mathias Wilhelms and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-22 with Technology & Engineering categories.
Multiscale modeling of cardiac electrophysiology helps to better understand the underlying mechanisms of atrial fibrillation, acute cardiac ischemia and pharmacological treatment. For this purpose, measurement data reflecting these conditions have to be integrated into models of cardiac electrophysiology. Several methods for this model adaptation are introduced in this thesis. The resulting effects are investigated in multiscale simulations ranging from the ion channel up to the body surface.AbstractEnglisch = Multiscale modeling of cardiac electrophysiology helps to better understand the underlying mechanisms of atrial fibrillation, acute cardiac ischemia and pharmacological treatment. For this purpose, measurement data reflecting these conditions have to be integrated into models of cardiac electrophysiology. Several methods for this model adaptation are introduced in this thesis. The resulting effects are investigated in multiscale simulations ranging from the ion channel up to the body surface.
European Distribution And Supply Chain Logistics
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Author : Ad R. Van Goor
language : en
Publisher: Routledge
Release Date : 2019-11-11
European Distribution And Supply Chain Logistics written by Ad R. Van Goor and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-11 with Business & Economics categories.
A broad vision of supply chain management is necessary to implement European distribution successfully. European Distribution and Supply Chain Logistics focuses on logistics in the European region. This book discusses proven concepts and do's & don'ts for European distribution, as well as for supply chain logistics across three clusters: Distribution and supply chain management Fundamentals of European distribution logistics Demand and supply chain management Each chapter starts with an awareness case and ends with fifteen questions for discussion, a real life case and five reflecting questions. Based on this formula the book is well-suited for students and practitioners in the area of logistics and supply chain management.
Multiscale Cohort Modeling Of Atrial Electrophysiology Risk Stratification For Atrial Fibrillation Through Machine Learning On Electrocardiograms
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Author : Nagel, Claudia
language : en
Publisher: KIT Scientific Publishing
Release Date : 2023-04-24
Multiscale Cohort Modeling Of Atrial Electrophysiology Risk Stratification For Atrial Fibrillation Through Machine Learning On Electrocardiograms written by Nagel, Claudia and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-24 with categories.
An early detection and diagnosis of atrial fibrillation sets the course for timely intervention to prevent potentially occurring comorbidities. Electrocardiogram data resulting from electrophysiological cohort modeling and simulation can be a valuable data resource for improving automated atrial fibrillation risk stratification with machine learning techniques and thus, reduces the risk of stroke in affected patients.
Modeling Human Atrial Patho Electrophysiology From Ion Channels To Ecg Substrates Pharmacology Vulnerability And P Waves
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Author : Loewe, Axel
language : en
Publisher: KIT Scientific Publishing
Release Date : 2016-08-03
Modeling Human Atrial Patho Electrophysiology From Ion Channels To Ecg Substrates Pharmacology Vulnerability And P Waves written by Loewe, Axel and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-03 with Technology (General) categories.
Half of the patients suffering from atrial fibrillation (AF) cannot be treated adequately, today. This book presents multi-scale computational methods to advance our understanding of patho-mechanisms, to improve the diagnosis of patients harboring an arrhythmogenic substrate, and to tailor therapy. The modeling pipeline ranges from ion channels on the subcellular level up to the ECG on the body surface. The tailored therapeutic approaches carry the potential to reduce the burden of AF.
A Multiscale In Silico Study To Characterize The Atrial Electrical Activity Of Patients With Atrial Fibrillation A Translational Study To Guide Ablation Therapy
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Author : Sánchez Arciniegas, Jorge Patricio
language : en
Publisher: KIT Scientific Publishing
Release Date : 2022-05-30
A Multiscale In Silico Study To Characterize The Atrial Electrical Activity Of Patients With Atrial Fibrillation A Translational Study To Guide Ablation Therapy written by Sánchez Arciniegas, Jorge Patricio and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-30 with Medical categories.
The atrial substrate undergoes electrical and structural remodeling during atrial fibrillation. Detailed multiscale models were used to study the effect of structural remodeling induced at the cellular and tissue levels. Simulated electrograms were used to train a machine-learning algorithm to characterize the substrate. Also, wave propagation direction was tracked from unannotated electrograms. In conclusion, in silico experiments provide insight into electrograms' information of the substrate.
Characterizing Cardiac Electrophysiology During Radiofrequency Ablation An Integrative Ex Vivo In Silico And In Vivo Approach
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Author : Pollnow, Stefan
language : en
Publisher: KIT Scientific Publishing
Release Date : 2019-04-23
Characterizing Cardiac Electrophysiology During Radiofrequency Ablation An Integrative Ex Vivo In Silico And In Vivo Approach written by Pollnow, Stefan and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-23 with Technology (General) categories.
Catheter ablation is a major treatment for atrial tachycardias. Hereby, the precise monitoring of the lesion formation is an important success factor. This book presents computational, wet-lab, and clinical studies with the aim of evaluating the signal characteristics of the intracardiac electrograms (IEGMs) recorded around ablation lesions from different perspectives. The detailed analysis of the IEGMs can optimize the description of durable and complex lesions during the ablation procedure.
Formation Of Intracardiac Electrograms Under Physiological And Pathological Conditions
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Author : Keller, Matthias
language : en
Publisher: KIT Scientific Publishing
Release Date : 2014-09-09
Formation Of Intracardiac Electrograms Under Physiological And Pathological Conditions written by Keller, Matthias and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-09 with Technology & Engineering categories.
This work presents methods to advance electrophysiological simulations of intracardiac electrograms (IEGM). An experimental setup is introduced, which combines electrical measurements of extracellular potentials with a method for optical acquisition of the transmembrane voltage in-vitro. Thereby, intracardiac electrograms can be recorded under defined conditions. Using experimental and clinical signals, detailed simulations of IEGMs are parametrized, which can support clinical diagnosis.
Ecg Imaging Of Ventricular Activity In Clinical Applications
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Author : Schulze, Walther H. W.
language : en
Publisher: KIT Scientific Publishing
Release Date : 2015-08-12
Ecg Imaging Of Ventricular Activity In Clinical Applications written by Schulze, Walther H. W. and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-12 with Technology (General) categories.
ECG imaging was performed in humans to reconstruct ventricular activation patterns and localize their excitation origins. The precision of the non-invasive reconstructions was evaluated against invasive measurements and found to be in line with the state-of-the-art literature. Statistics were produced for various excitation origins and reveal the beat-to-beat robustness of the imaging method.
Development And Evaluation Of Coded Aperture Reconstruction Methods For Intraoperative Gamma Cameras
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Author : Meißner, Tobias
language : en
Publisher: KIT Scientific Publishing
Release Date : 2025-01-20
Development And Evaluation Of Coded Aperture Reconstruction Methods For Intraoperative Gamma Cameras written by Meißner, Tobias and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-20 with categories.
Intraoperative Gamma Cameras are becoming increasingly common for radio-guided surgery. Coded Aperture Imaging has been proposed as a collimation technique, because it offers a better trade-off between sensitivity and spatial resolution, but requires image reconstruction. Therefore, a Convolutional Encoder-Decoder Network was developed and quantitatively compared with analytical methods. Furthermore, 3D-localization of point-like sources was investigated.
Cardiac Electrophysiology From Cell To Bedside E Book
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Author : Douglas P. Zipes
language : en
Publisher: Elsevier Health Sciences
Release Date : 2017-05-13
Cardiac Electrophysiology From Cell To Bedside E Book written by Douglas P. Zipes and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-13 with Medical categories.
Rapid advancements in cardiac electrophysiology require today’s health care scientists and practitioners to stay up to date with new information both at the bench and at the bedside. The fully revised 7th Edition of Cardiac Electrophysiology: From Cell to Bedside, by Drs. Douglas Zipes, Jose Jalife, and William Stevenson, provides the comprehensive, multidisciplinary coverage you need, including the underlying basic science and the latest clinical advances in the field. An attractive full-color design features color photos, tables, flow charts, ECGs, and more. All chapters have been significantly revised and updated by global leaders in the field, including 19 new chapters covering both basic and clinical topics. New topics include advances in basic science as well as recent clinical technology, such as leadless pacemakers; catheter ablation as a new class I recommendation for atrial fibrillation after failed medical therapy; current cardiac drugs and techniques; and a new video library covering topics that range from basic mapping (for the researcher) to clinical use (implantations). Each chapter is packed with the latest information necessary for optimal basic research as well as patient care, and additional figures, tables, and videos are readily available online. New editor William G. Stevenson, highly regarded in the EP community, brings a fresh perspective to this award-winning text.