Multiscale Modeling Of Cardiac Electrophysiology Adaptation To Atrial And Ventricular Rhythm Disorders And Pharmacological Treatment


Multiscale Modeling Of Cardiac Electrophysiology Adaptation To Atrial And Ventricular Rhythm Disorders And Pharmacological Treatment
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Multiscale Modeling Of Cardiac Electrophysiology Adaptation To Atrial And Ventricular Rhythm Disorders And Pharmacological Treatment


Multiscale Modeling Of Cardiac Electrophysiology Adaptation To Atrial And Ventricular Rhythm Disorders And Pharmacological Treatment
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Author : Mathias Wilhelms
language : en
Publisher: KIT Scientific Publishing
Release Date : 2014-05-22

Multiscale Modeling Of Cardiac Electrophysiology Adaptation To Atrial And Ventricular Rhythm Disorders And Pharmacological Treatment written by Mathias Wilhelms and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-22 with Technology & Engineering categories.


Multiscale modeling of cardiac electrophysiology helps to better understand the underlying mechanisms of atrial fibrillation, acute cardiac ischemia and pharmacological treatment. For this purpose, measurement data reflecting these conditions have to be integrated into models of cardiac electrophysiology. Several methods for this model adaptation are introduced in this thesis. The resulting effects are investigated in multiscale simulations ranging from the ion channel up to the body surface.AbstractEnglisch = Multiscale modeling of cardiac electrophysiology helps to better understand the underlying mechanisms of atrial fibrillation, acute cardiac ischemia and pharmacological treatment. For this purpose, measurement data reflecting these conditions have to be integrated into models of cardiac electrophysiology. Several methods for this model adaptation are introduced in this thesis. The resulting effects are investigated in multiscale simulations ranging from the ion channel up to the body surface.



Multiscale Cohort Modeling Of Atrial Electrophysiology Risk Stratification For Atrial Fibrillation Through Machine Learning On Electrocardiograms


Multiscale Cohort Modeling Of Atrial Electrophysiology Risk Stratification For Atrial Fibrillation Through Machine Learning On Electrocardiograms
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Author : Nagel, Claudia
language : en
Publisher: KIT Scientific Publishing
Release Date : 2023-04-24

Multiscale Cohort Modeling Of Atrial Electrophysiology Risk Stratification For Atrial Fibrillation Through Machine Learning On Electrocardiograms written by Nagel, Claudia and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-24 with categories.


An early detection and diagnosis of atrial fibrillation sets the course for timely intervention to prevent potentially occurring comorbidities. Electrocardiogram data resulting from electrophysiological cohort modeling and simulation can be a valuable data resource for improving automated atrial fibrillation risk stratification with machine learning techniques and thus, reduces the risk of stroke in affected patients.



Modeling Human Atrial Patho Electrophysiology From Ion Channels To Ecg Substrates Pharmacology Vulnerability And P Waves


Modeling Human Atrial Patho Electrophysiology From Ion Channels To Ecg Substrates Pharmacology Vulnerability And P Waves
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Author : Loewe, Axel
language : en
Publisher: KIT Scientific Publishing
Release Date : 2016-08-03

Modeling Human Atrial Patho Electrophysiology From Ion Channels To Ecg Substrates Pharmacology Vulnerability And P Waves written by Loewe, Axel and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-03 with categories.




A Multiscale In Silico Study To Characterize The Atrial Electrical Activity Of Patients With Atrial Fibrillation A Translational Study To Guide Ablation Therapy


A Multiscale In Silico Study To Characterize The Atrial Electrical Activity Of Patients With Atrial Fibrillation A Translational Study To Guide Ablation Therapy
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Author : Sánchez Arciniegas, Jorge Patricio
language : en
Publisher: KIT Scientific Publishing
Release Date : 2022-05-30

A Multiscale In Silico Study To Characterize The Atrial Electrical Activity Of Patients With Atrial Fibrillation A Translational Study To Guide Ablation Therapy written by Sánchez Arciniegas, Jorge Patricio and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-30 with Medical categories.


The atrial substrate undergoes electrical and structural remodeling during atrial fibrillation. Detailed multiscale models were used to study the effect of structural remodeling induced at the cellular and tissue levels. Simulated electrograms were used to train a machine-learning algorithm to characterize the substrate. Also, wave propagation direction was tracked from unannotated electrograms. In conclusion, in silico experiments provide insight into electrograms' information of the substrate.



Characterizing Cardiac Electrophysiology During Radiofrequency Ablation An Integrative Ex Vivo In Silico And In Vivo Approach


Characterizing Cardiac Electrophysiology During Radiofrequency Ablation An Integrative Ex Vivo In Silico And In Vivo Approach
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Author : Pollnow, Stefan
language : en
Publisher: KIT Scientific Publishing
Release Date : 2019-04-23

Characterizing Cardiac Electrophysiology During Radiofrequency Ablation An Integrative Ex Vivo In Silico And In Vivo Approach written by Pollnow, Stefan and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-23 with categories.




Formation Of Intracardiac Electrograms Under Physiological And Pathological Conditions


Formation Of Intracardiac Electrograms Under Physiological And Pathological Conditions
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Author : Keller, Matthias
language : en
Publisher: KIT Scientific Publishing
Release Date : 2014-09-09

Formation Of Intracardiac Electrograms Under Physiological And Pathological Conditions written by Keller, Matthias and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-09 with Technology & Engineering categories.


This work presents methods to advance electrophysiological simulations of intracardiac electrograms (IEGM). An experimental setup is introduced, which combines electrical measurements of extracellular potentials with a method for optical acquisition of the transmembrane voltage in-vitro. Thereby, intracardiac electrograms can be recorded under defined conditions. Using experimental and clinical signals, detailed simulations of IEGMs are parametrized, which can support clinical diagnosis.



Ecg Imaging Of Ventricular Activity In Clinical Applications


Ecg Imaging Of Ventricular Activity In Clinical Applications
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Author : Schulze, Walther H. W.
language : en
Publisher: KIT Scientific Publishing
Release Date : 2015-08-12

Ecg Imaging Of Ventricular Activity In Clinical Applications written by Schulze, Walther H. W. and has been published by KIT Scientific Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-12 with Technology (General) categories.


ECG imaging was performed in humans to reconstruct ventricular activation patterns and localize their excitation origins. The precision of the non-invasive reconstructions was evaluated against invasive measurements and found to be in line with the state-of-the-art literature. Statistics were produced for various excitation origins and reveal the beat-to-beat robustness of the imaging method.



Cardiac Electrophysiology From Cell To Bedside E Book


Cardiac Electrophysiology From Cell To Bedside E Book
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Author : Douglas P. Zipes
language : en
Publisher: Elsevier Health Sciences
Release Date : 2017-05-13

Cardiac Electrophysiology From Cell To Bedside E Book written by Douglas P. Zipes and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-13 with Medical categories.


Rapid advancements in cardiac electrophysiology require today’s health care scientists and practitioners to stay up to date with new information both at the bench and at the bedside. The fully revised 7th Edition of Cardiac Electrophysiology: From Cell to Bedside, by Drs. Douglas Zipes, Jose Jalife, and William Stevenson, provides the comprehensive, multidisciplinary coverage you need, including the underlying basic science and the latest clinical advances in the field. An attractive full-color design features color photos, tables, flow charts, ECGs, and more. All chapters have been significantly revised and updated by global leaders in the field, including 19 new chapters covering both basic and clinical topics. New topics include advances in basic science as well as recent clinical technology, such as leadless pacemakers; catheter ablation as a new class I recommendation for atrial fibrillation after failed medical therapy; current cardiac drugs and techniques; and a new video library covering topics that range from basic mapping (for the researcher) to clinical use (implantations). Each chapter is packed with the latest information necessary for optimal basic research as well as patient care, and additional figures, tables, and videos are readily available online. New editor William G. Stevenson, highly regarded in the EP community, brings a fresh perspective to this award-winning text. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos (including video updates), glossary, and references from the book on a variety of devices.



Encyclopedia Of Cell Biology


Encyclopedia Of Cell Biology
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-08-07

Encyclopedia Of Cell Biology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-07 with Science categories.


The Encyclopedia of Cell Biology, Four Volume Set offers a broad overview of cell biology, offering reputable, foundational content for researchers and students across the biological and medical sciences. This important work includes 285 articles from domain experts covering every aspect of cell biology, with fully annotated figures, abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, the Encyclopedia of Cell Biology provides a fully cross-referenced, one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences. Fully annotated color images and videos for full comprehension of concepts, with layered content for readers from different levels of experience Includes information on cytokinesis, cell biology, cell mechanics, cytoskeleton dynamics, stem cells, prokaryotic cell biology, RNA biology, aging, cell growth, cell Injury, and more In-depth linking to Academic Press/Elsevier content and additional links to outside websites and resources for further reading A one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences



Multiscale Modelling And Simulation


Multiscale Modelling And Simulation
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Author : Sabine Attinger
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-07-12

Multiscale Modelling And Simulation written by Sabine Attinger and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-07-12 with Mathematics categories.


In August 2003, ETHZ Computational Laboratory (CoLab), together with the Swiss Center for Scientific Computing in Manno and the Università della Svizzera Italiana (USI), organized the Summer School in "Multiscale Modelling and Simulation" in Lugano, Switzerland. This summer school brought together experts in different disciplines to exchange ideas on how to link methodologies on different scales. Relevant examples of practical interest include: structural analysis of materials, flow through porous media, turbulent transport in high Reynolds number flows, large-scale molecular dynamic simulations, ab-initio physics and chemistry, and a multitude of others. Though multiple scale models are not new, the topic has recently taken on a new sense of urgency. A number of hybrid approaches are now created in which ideas coming from distinct disciplines or modelling approaches are unified to produce new and computationally efficient techniques.