Muse Cells
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Muse Cells
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Author : Mari Dezawa
language : en
Publisher: Springer
Release Date : 2018-11-27
Muse Cells written by Mari Dezawa and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-27 with Medical categories.
This book provides the first comprehensive account of multilineage-differentiating stress-enduring (Muse) cells, a pluripotent and non-tumorigenic subpopulation of mesenchymal stem cells (MSCs) that have the ability to detect damage signals, migrate to damaged sites, and spontaneously differentiate into cells compatible with the affected tissue, thereby enabling repair of all tissue types. The coverage encompasses everything from the basic properties of Muse cells to their tissue repair effects and potential clinical applications—for example, in acute myocardial infarction, stroke, skin injuries and ulcers, renal failure, and liver disease. An important technical chapter provides a practical and precise protocol for the isolation of Muse cells, which will enable readers to use Muse cells in their own research. In offering fascinating insights into the strategic organization of the body’s reparative function and explaining how full utilization of Muse cells may significantly enhance the effectiveness of MSC treatment, the book will be of high value for Ph.D. students, postdocs, basic researchers, clinical doctors, and industrial developers.
Cell Biology And Translational Medicine Volume 11
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Author : Kursad Turksen
language : en
Publisher: Springer Nature
Release Date : 2021-07-20
Cell Biology And Translational Medicine Volume 11 written by Kursad Turksen and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-20 with Science categories.
Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the tenth volume of a continuing series.
Cell Engineering And Regeneration
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Author : Heinz Redl
language : en
Publisher: Springer
Release Date : 2017-02-16
Cell Engineering And Regeneration written by Heinz Redl and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-16 with Technology & Engineering categories.
This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.
Stem Cell Therapy
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Author : Fouad Sabry
language : en
Publisher: One Billion Knowledgeable
Release Date : 2022-10-05
Stem Cell Therapy written by Fouad Sabry and has been published by One Billion Knowledgeable this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-05 with Medical categories.
What Is Stem Cell Therapy The use of a patient's own stem cells, either to cure or prevent a disease or condition, is the practice known as stem-cell therapy. As of the year 2016, hematopoietic stem cell transplantation is the only treatment that has been shown to be effective employing stem cells. The transplantation of bone marrow is the most common method used for this procedure; however, the cells may also be extracted from umbilical cord blood. Research is now being conducted to establish diverse sources for stem cells and to use stem-cell therapies for neurodegenerative disorders and ailments such as diabetes and heart disease. Additionally, research is being conducted to generate new stem cell sources. How You Will Benefit (I) Insights, and validations about the following topics: Chapter 1: Stem-cell therapy Chapter 2: Stem cell Chapter 3: Bone marrow Chapter 4: Hematopoietic stem cell transplantation Chapter 5: Embryonic stem cell Chapter 6: Regenerative medicine Chapter 7: Cell therapy Chapter 8: Cord blood Chapter 9: Adult stem cell Chapter 10: Stem-cell line Chapter 11: Knee cartilage replacement therapy Chapter 12: Cardiomyoplasty Chapter 13: Stem cell transplantation for articular cartilage repair Chapter 14: Mesenchymal stem cell Chapter 15: Clinical uses of mesenchymal stem cells Chapter 16: Muse cell Chapter 17: Guo Mei Chapter 18: Spinal cord injury research Chapter 19: Stem cell secretome Chapter 20: Shimon Slavin Chapter 21: Stem cell fat grafting (II) Answering the public top questions about stem cell therapy. (III) Real world examples for the usage of stem cell therapy in many fields. (IV) 17 appendices to explain, briefly, 266 emerging technologies in each industry to have 360-degree full understanding of stem cell therapy' technologies. Who This Book Is For Professionals, undergraduate and graduate students, enthusiasts, hobbyists, and those who want to go beyond basic knowledge or information for any kind of stem cell therapy.
Scientific Principles Of Adipose Stem Cells
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Author : Lauren Kokai
language : en
Publisher: Academic Press
Release Date : 2021-08-19
Scientific Principles Of Adipose Stem Cells written by Lauren Kokai and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-19 with Science categories.
Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype. A section devoted to ASC biology, ASCs for stem cell therapy and regenerative medicine, and ASCs in tissue engineering applications are also included. The book is written for scientists and clinicians who are broadly familiar with stem cells and basic cell biology principles and those seeking advanced information on adipose stem cells. Coverage of basic adipose stem cell developmental biology (maturation process during embryogenesis) and mechanisms of regulating self-renewal and activation in the stem cell niche Includes important methods for isolation and characterizing ASCs, as well as known data any impact of human demographics (age, sex, BMI) on ASC phenotype An entire section dedicated to ASC biology, additional sections will be devoted to ASCs for stem cell therapy and regenerative medicine, as well as ASCs in tissue engineering applications
Cell Sources For Ipscs
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Author : Alexander Birbrair
language : en
Publisher: Academic Press
Release Date : 2021-05-09
Cell Sources For Ipscs written by Alexander Birbrair and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-09 with Science categories.
The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. Cell Sources for iPSCs, Volume 7 teaches readers about current advances in the field. It shares up-to-date comprehensive overviews of current advances in the field. This book describes the derivation of iPSCs from different sources in vitro, enabling us to study the cellular and molecular mechanisms involved in different pathologies. Further insights into these mechanisms will have important implications for our understanding of disease appearance, development, and progression. The authors focus on the modern state-of-art methodologies and the leading-edge concepts in the field of stem cell biology. In recent years, remarkable progress has been made in the obtention of iPSCs and their differentiation into several cell types, tissues, and organs using state-of-art techniques. These advantages facilitated identification of key targets and definition of the molecular basis of several disorders. Thus, this book is an attempt to describe the most recent developments in iPSCs biology, which is one of the rising hot topics in the field of molecular and cellular biology today. Here, we present a selected collection of detailed chapters on how we derive iPSCs from distinct sources. Ten chapters written by experts in the field summarize the present knowledge about different cell sources for iPSCs. This volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine, and organ transplantation and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine, and therapeutics Covers the following: myoblast-derived iPSCs, lymphoblastoid-derived iPSCs, amniotic fluid stem cell–derived iPSCs, spermatogonial stem cell–derived iPSCs, iPSCs derived from postmortem tissue, and more Contributed by world-renowned experts in the field
Cell Biology And Translational Medicine Volume 6
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Author : Kursad Turksen
language : en
Publisher: Springer Nature
Release Date : 2020-01-09
Cell Biology And Translational Medicine Volume 6 written by Kursad Turksen and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-09 with Science categories.
Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the sixth volume of a continuing series.
Vitiligo
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Author : Mauro Picardo
language : en
Publisher: Springer
Release Date : 2019-07-23
Vitiligo written by Mauro Picardo and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-23 with Medical categories.
Since the first edition of this book was published, new knowledge has been gained on Vitiligo. This widely revised and updated second edition, written by worldwide experts in the field, fully reflects this progress. The apparently, simple and poorly symptomatic presentation of the disease has been a strong disadvantage to its study, as compared to other common chronic skin disorders such as psoriasis and atopic dermatitis. A good skin-based angle of attack is also lacking because generalized Vitiligo is clearly epitomizing the view of skin diseases as simple targets of a systemic unknown dysregulation (diathesis). This view has mostly restricted Vitiligo to the manifestation of an auto-immune diathesis and skin events, which are easily detected using skin biopsies in most other situations, have not been precisely recorded, with the argument that a clinical diagnosis was sufficient for the management of the patient with Vitiligo. This richly illustrated second edition reflects the constant international effort to share the information gathered about this disorder at the clinical, pathophysiological and therapeutic levels. Its aim still being to bridge current knowledge at the clinical and investigative level, to point to the many unsolved issues, and to delineate future priorities for research.
Innovative Medicine
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Author : Kazuwa Nakao
language : en
Publisher: Springer
Release Date : 2015-10-13
Innovative Medicine written by Kazuwa Nakao and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-13 with Science categories.
This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.
Cardioprotection Against Acute Myocardial Infarction
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Author : Shinya Minatoguchi
language : en
Publisher: Springer Nature
Release Date : 2019-11-16
Cardioprotection Against Acute Myocardial Infarction written by Shinya Minatoguchi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-16 with Science categories.
This book will provide readers with a detailed understanding of the ischemic damage to the myocardium after myocardial infarction, as well as essential tools for the treatment of damaged heart after myocardial infarction. It discusses various methods such as pharmacological pre- and post-conditioning, cytokine therapy, and cell therapy especially using Muse cells.The coverage of Muse cell therapy, which includes the latest work done by the author and his collaborators, is a unique feature of the book. Muse cells have self-renewability and have ability to differentiate into cells with the characteristics of all three germ layers from a single cell, while they are non-tumorigenic. It is the first book to feature the Muse cell therapy, which may offer the new promising therapeutic strategy for acute myocardial infarction.