Myb Transcription Factors
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Myb Transcription Factors Their Role In Growth Differentiation And Disease
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Author : Jon Frampton
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-13
Myb Transcription Factors Their Role In Growth Differentiation And Disease written by Jon Frampton and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-13 with Medical categories.
This volume represents the first collection of articles contributed by research leaders working on the Myb family of transcriptional regulatory proteins. In more than twenty chapters the authors discuss the range of biological processes and diverse cell types in which Myb proteins operate. Although concentrating on the three vertebrate Myb family members, homologues from lower species are also discussed because of the light they are able to shed on the evolution and function of these proteins. Individual chapters describe the involvement of Myb proteins, in particular c-Myb, in normal and diseased development and function of many tissues including haemopoietic cells, blood vessels, the gastrointestinal tract and the brain. Several chapters explore the mechanistic details of the action of Myb proteins, especially structural features, their interaction with DNA and other regulatory proteins, and the variety of genes that are regulatory targets for this group of transcription factors. This work will be of interest to those working directly in the field and also to the wider research community investigating the transcriptional regulation of development, differentiation and growth. The therapeutic potential of manipulating Myb function is also discussed making the book appealing to clinician scientists in several fields including haematology, oncology and cardiology.
Myb Transcription Factors
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Author : Jon Frampton
language : en
Publisher:
Release Date : 2014-09-01
Myb Transcription Factors written by Jon Frampton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-01 with categories.
Functional Evolution Of R2r3 Myb Transcription Factors In The Grasses
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Author : Anusha P. Dias
language : en
Publisher:
Release Date : 2004
Functional Evolution Of R2r3 Myb Transcription Factors In The Grasses written by Anusha P. Dias and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Grasses categories.
Abstract: Transcription factors are emerging as key players in the origin of evolutionary novelties and as powerful tools to manipulating plant metabolism. The number of R2R3 Myb genes have amplified dramatically in the plants, where they are involved in the regulation of plant form and metabolic diversity. However, the function of most plant R2R3 Myb genes remains to be determined, primarily due to the lack of phenotypes of loss-of-function mutants. Here, we have investigated the evolutionary origins of R2R3 Myb genes and started to establish the functions of recently duplicated R2R3 Myb genes in maize through a gain-of-function approach. We have identified discrete evolutionary steps involved in the formation of plant specific R2R3 Myb genes from widely distribute R1R2R3 Myb genes. We have used the Black Mexican Sweet (BMS) maize cell culture system to investigate the consequences on the accumulation of metabolites of expressing the novel R2R3 MYB transcription factor ZmMYB-IF35. We demonstrate that, despite the high amino acid identity in the MYB domain with the P1 regulator of 3-deoxy-flavonoid biosynthesis, ZmMyb-IF35 does not induce the accumulation of flavonoids. However, similar to P1, ZmMyb-IF35 induces the accumulation of ferulic and chlorogenic acids, as well as several other compounds not found in the control BMS lines or in P1-expressing lines, suggesting a promising role of ZmMyb-IF35 for engineering the accumulation of various phenolic compounds. Together, our studies indicate that despite their recent common evolutionary origins, ZmMyb-IF35 and P1 have functionally diverged. Theses studies also suggest a possible correlation between phylogeny and function. Whether this is a general characteristic common to all regulatory genes remains to be determined.
The Evolution Of Myb Transcription Factors In Gossypium
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Author : Maria Louise Cedroni
language : en
Publisher:
Release Date : 2001
The Evolution Of Myb Transcription Factors In Gossypium written by Maria Louise Cedroni and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.
The genus Gossypium produces an important crop plant, cotton. Cotton fibers are single-celled trichomes that develop on the maturing ovule. The commercial quality of these fibers varies greatly within the genus. Such morphological variation may be due to differential expression of the genes responsible for fiber development. It has been proposed that these morphological differences could be related to the evolution of transcription factors and their expression. Six myb transcription factors are expressed during fiber initiation in Gossypium hirsutum. Moreover, some members of the myb transcription factor family have been implicated in trichome development in other plants. The molecular evolution of these six fiber-expressed genes was investigated in three members of the genus Gossypium, as well as the evolution of expression in both diploid and allotetraploid cotton.
Interplay Between Unusual Myb Transcription Factors And Their Role In Cell Size Regulation In Plants
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Author : Katja Marlene Machemer-Noonan
language : en
Publisher:
Release Date : 2014
Interplay Between Unusual Myb Transcription Factors And Their Role In Cell Size Regulation In Plants written by Katja Marlene Machemer-Noonan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Additionally, as modification of lignocellulosic biomass is becoming progressively more imperative in the generation of cost-efficient biofuels, the control of phenylpropanoid biosynthesis plays an important role in the achievement of this goal. We identified two R2R3-MYB transcription factors, ZmMYB40 and ZmMYB95, which potentially present a way of fine-tuning lignin composition in maize cell walls, in combinatorial gene expression control with two negative regulators of the phenylpropanoid pathway, ZmMYB31 and ZmMYB42. Maize plants harboring RNAi constructs against ZmMYB40 display statistically lower expression for a number of pathway genes, further supporting this hypothesis. Further, RNA-Seq of rice plants over-expressing the rice homolog of ZmMYB31 elucidates its transcriptional effect beyond those targets already identified in maize, expanding its possible impact.
Functional Characterization Of Two Myb Transcription Factors Myb95 And Myb47 In Arabidopsis Thaliana
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Author : Ke Xu
language : en
Publisher:
Release Date : 2016
Functional Characterization Of Two Myb Transcription Factors Myb95 And Myb47 In Arabidopsis Thaliana written by Ke Xu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
Genetics Of R2r3 Myb Transcription Factors In Erythronium
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Author : Sophie Klingborg
language : en
Publisher:
Release Date : 2022
Genetics Of R2r3 Myb Transcription Factors In Erythronium written by Sophie Klingborg and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.
Structural And Functional Evolution Of R2r3 Myb Transcription Factors
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Author :
language : en
Publisher:
Release Date : 2018
Structural And Functional Evolution Of R2r3 Myb Transcription Factors written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
The Role Of Myb Transcription Factors In The Regulation Of Bone Marrow Derived Mesenchymal Cells
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Author : Ana Isabel Salvador Camelo
language : en
Publisher:
Release Date : 2008
The Role Of Myb Transcription Factors In The Regulation Of Bone Marrow Derived Mesenchymal Cells written by Ana Isabel Salvador Camelo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.
Myb Transcription Factors And The Control Of Secondary Metabolism In Tomato
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Author : Rachel Holford
language : en
Publisher:
Release Date : 1999
Myb Transcription Factors And The Control Of Secondary Metabolism In Tomato written by Rachel Holford and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.