Mycobacterium Tuberculosis
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Mycobacterium Tuberculosis Protocols
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Author : Tanya Parish
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-01
Mycobacterium Tuberculosis Protocols written by Tanya Parish and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-01 with Medical categories.
The aim of this book is to provide detailed protocols for studying the molecular biology of the pathogen Mycobacterium tuberculosis, and its int- actions with host cells. As established mycobacterial laboratories move - wards exploiting the genome, and laboratories with expertise in other fields apply them to mycobacteria, both traditional and novel methodologies need to be reviewed. Thus the chapters in Mycobacterium tuberculosis Protocols range from perspectives on storage of strains and safety issues to the application of the latest functional genomics technologies. The last few years have been remarkable ones for research into M. tuber- losis. The most important landmark by far has been the completion of the genome sequence of the widely studied H37Rv strain (1). We can now predict every protein and RNA molecule made by the pathogen. This information is or will soon be enriched by the addition of genome sequences of other strains from the M. tuberculosis complex: a second strain of M. tuberculosis, My- bacterium bovis, and the vaccine strain, M. bovis BCG. Valuable comparative data will also be provided by the genome sequences of Mycobacterium leprae, Mycobacterium avium, and Streptomyces coelicolor. Another recent milestone for M. tuberculosis has been the development of efficient mutagenesis me- odologies, the lack of which has been a major handicap in functional studies.
Mycobacterium Tuberculosis Pathogenesis Infection Prevention And Treatment
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Author : Davide Maria Ferraris
language : en
Publisher:
Release Date : 2020
Mycobacterium Tuberculosis Pathogenesis Infection Prevention And Treatment written by Davide Maria Ferraris and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global Tuberculosis Report (2019) edited by the World Health Organization (WHO), TB is considered the ninth cause of death worldwide and the leading cause of mortality by a single infectious agent, with the highest rate of infections and death toll rate mostly concentrated in developing and low-income countries. We present here the editorial section to the Special Issue entitled “Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment” that includes 7 research articles and a review. The scientific contributions included in the Special Issue mainly focus on the characterization of MTB strains emerging in TB endemic countries as well as on multiple mechanisms adopted by the bacteria to resist and to adapt to antitubercular therapies.
Mycobacterium Tuberculosis Molecular Infection Biology Pathogenesis Diagnostics And New Interventions
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Author : Seyed Ehtesham Hasnain
language : en
Publisher: Springer Nature
Release Date : 2019-11-30
Mycobacterium Tuberculosis Molecular Infection Biology Pathogenesis Diagnostics And New Interventions written by Seyed Ehtesham Hasnain and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-30 with Medical categories.
This book reviews recent advances in the molecular and infection biology, pathology, and molecular epidemiology of Mycobacterium tuberculosis, as well as the identification and validation of novel molecular drug targets for the treatment of this mycobacterial disease. Despite being completely curable, tuberculosis is still one of the leading global causes of death. M. tuberculosis, the causative organism – one of the smartest pathogens known – adopts highly intelligent strategies for survival and pathogenesis. Presenting a wealth of information on the molecular infection biology of M. tuberculosis, as well as nontuberculous mycobacteria (NTM), the book provides an overview of the functional role of the PE/PPE group of proteins, which is exclusive to the genus Mycobacteria, of host-pathogen interactions, and virulence. It also explores the pathogenesis of the infection, pathology, epidemiology, and diagnosis of NTM. Finally it discusses current and novel approaches in vaccine development against tuberculosis, including the role of nanotechnology. With state-of-the-art contributions from experts in the respective domains, this book is an informative resource for practitioners as well as medical postgraduate students and researchers.
Tuberculosis And Nontuberculous Mycobacterial Infections
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Author : David L. Schlossberg
language : en
Publisher: John Wiley & Sons
Release Date : 2020-07-10
Tuberculosis And Nontuberculous Mycobacterial Infections written by David L. Schlossberg and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-10 with Medical categories.
For Tuberculosis and Nontuberculous Mycobacterial Infections, Dr. Schlossberg assembled an international team of experts to write about nearly every facet of the prevention, diagnosis, and treatment of tuberculosis and nontuberculous mycobacterial infections. In addition to presenting the latest clinical data, epidemiological findings, and policy and strategy recommendations of the World Health Organization, four new chapters cover topics of critical importance: The role of therapeutic drug monitoring in mycobacterial infections The public health issues of refugees and migrants, and their exposure and transmission of tuberculosis resulting from humanitarian crises Diabetes mellitus as a significant risk factor for tuberculosis The increased risk of tuberculosis reactivation in people taking tumor necrosis factor alpha inhibitors and other biopharmaceuticals Other chapters provide detailed information on the clinical, public health, and policy aspects of tracking and treating tuberculosis, including: The many presentations of tuberculosis, from pulmonary to ocular and cardiovascular to urogenital The complications that tuberculosis and antituberculosis therapy cause to the hematologic and endocrine systems Tuberculosis during pregnancy and in infants and children Treatment of multidrug-resistant tuberculosis and extensively drugresistant tuberculosis Development of new vaccines Nontuberculous infections caused by mycobacteria found throughout our environment The seventh edition of Tuberculosis and Nontuberculous Mycobacterial Infections is an essential resource for anyone working to prevent and treat tuberculosis and associated infections, from infectious disease specialists to scientists, policymakers, and epidemiologists.
Mycobacterium Tuberculosis
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Author : Mauro Bendinelli
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Mycobacterium Tuberculosis written by Mauro Bendinelli and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Tuberculosis once again occupies a special position in the areas of infec tious diseases and microbiology. This disease has been important to mankind since even before biblical times. Tuberculosis has been a major cause of morbidity and mortality in humans, especially in highly ur banized Europe, until a few decades ago. Indeed, this disease became a center of many novels, plays, and operas, since it appeared to be quite popular to have the heroine dying of "consumption. " Most importantly, tuberculosis also became the focus of attention for many investigations during the 19th and even the 20th centuries. Major advances were made in the areas of isolation and identification of M. tuberculosis and related microorganisms. The discovery, by Robert Koch, that tuberculosis was caused by an infectious agent revolutionized our thinking about dis eases. Koch's postulates were developed with tuberculosis in mind and became a focal point for many advances in microbiology and medicine. Studies with mycobacteria as a central focus have also led to revolu tionary new concepts about immunology in general. Koch himself showed that those exposed to M. tuberculosis develop a skin hypersen sitivity or allergy to the microorganism's antigens, an observation which was the starting point for many important developments. Indeed, imme diate-type hypersensitivity and atopic or IgE-mediated allergy were de fined in relation to the delayed-type cutaneous hypersensitivity evi denced with the tubercle bacillus.
Pathogenesis Of Mycobacterium Tuberculosis And Its Interaction With The Host Organism
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Author : Jean Pieters
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-09
Pathogenesis Of Mycobacterium Tuberculosis And Its Interaction With The Host Organism written by Jean Pieters and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-09 with Medical categories.
Mycobacterium tuberculosis is one of the most notorious pathogens on earth, causing the death of approximately 1.5 million people annually. A major problem in the fight against tuberculosis is the emergence of strains that have acquired resistance to all available antibiotics. One key to the success of M. tuberculosis as a pathogen is its ability to circumvent host immune responses at different levels. This is not only a result of the special makeup of M. tuberculosis in terms of genetic diversity and DNA metabolism and its possession of specialized secretion systems, but also of its ability to hijack the host’s innate immune defence mechanisms. In this volume, researchers from different disciplines provide a topical overview of the diverse mechanisms that contribute to the virulence of M. tuberculosis, ranging from their genetic, metabolic and molecular makeup, as well as the complex strategies these bacteria utilize to escape immune destruction within infected hosts.
Case Studies In Infectious Disease Mycobacterium Tuberculosis
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Author : Peter Lydyard
language : en
Publisher: Garland Science
Release Date : 2009-12
Case Studies In Infectious Disease Mycobacterium Tuberculosis written by Peter Lydyard and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12 with Medical categories.
Case Studies in Infectious Disease: Mycobacterium tuberculosis presents the natural history of this infection from point of entry of the pathogen through pathogenesis, clinical presentation, diagnosis, and treatment. A set of core questions explores the nature, causation, host response, manifestations, and management of this infectious process. This case also includes summary bullet points, questions and answers, and references.
Understanding Tuberculosis
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Author : Pere-Joan Cardona
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-02-24
Understanding Tuberculosis written by Pere-Joan Cardona and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-24 with Medical categories.
Mycobacterium tuberculosis in an attempt to understand the extent to which the bacilli has adapted itself to the host and to its final target. On the other hand, there is a section in which other specialists discuss how to manipulate this immune response to obtain innovative prophylactic and therapeutic approaches to truncate the intimal co-evolution between Mycobacterium tuberculosis and the Homo sapiens.
Isolation And Identification Of Mycobacterium Tuberculosis
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Author : Bobby E. Strong
language : en
Publisher:
Release Date : 1981
Isolation And Identification Of Mycobacterium Tuberculosis written by Bobby E. Strong and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Mycobacterium tuberculosis categories.
Atlas Of Mycobacterium Tuberculosis
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Author : Ali Akbar Velayati
language : en
Publisher: Academic Press
Release Date : 2016-09-30
Atlas Of Mycobacterium Tuberculosis written by Ali Akbar Velayati and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-30 with Medical categories.
Atlas of Mycobacterium Tuberculosis reveals in-depth information about mycobacterium tuberculosis which has never before been reported. Using atomic force microscopy (AFM), the in-depth phenotypic interaction that occurs in different stages of the tuberculosis lifecycle is illustrated, including resting, exponential, and dormant states. Coverage also includes the macroscopic and microscopic anatomy of mycobacterium, including pigmentation, morphology of colonies, size and shape, and the phenotypic changes from susceptible to resistant, all shown with images from electronic and atomic force microscopes. This book will open a new window into the results of molecular changes at the cellular level, guiding researchers and scientists to think in new ways about the area of cell wall and the reproductive and drug resistance phenomena surrounding tuberculosis. Identifies the different stages and morphological aspects of mycobacterium tuberculosis with the use of new microscopy techniques Includes never-before-seen photographs from the personal collection and scientific achievement of the authors Outlines the nature of the lifecycle of mycobacterium tuberculosis in relation to adaptation in humans