Myogenesis
DOWNLOAD
FREE 30 Days
Download Myogenesis PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Myogenesis book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Myogenesis
DOWNLOAD
FREE 30 Days
Author :
language : en
Publisher: Academic Press
Release Date : 2011-07-22
Myogenesis written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-22 with Science categories.
Myogenesis is the formation of muscular tissue, in particular during embryonic development. This new volume in the "Current topics in Developmental Biology" series covers chapters on such topics as Control of nuclear import during myogenesis, Pathways contributing to fibrosis in skeletal muscle, and Ferlin family members in myogenesis. With an international team of authors, this volume is a must-have addition for researchers and students alike. This new volume in the "Current topics in Developmental Biology" series covers chapters on such topics as Control of nuclear import during myogenesis, Pathways contributing to fibrosis in skeletal muscle, and Ferlin family members in myogenesis With an international team of authors, this volume is a must-have addition for researchers and students alike
Myogenesis In Development And Disease
DOWNLOAD
FREE 30 Days
Author :
language : en
Publisher: Academic Press
Release Date : 2018-01-03
Myogenesis In Development And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-03 with Science categories.
Myogenesis in Development and Disease, Volume 126, the latest volume in the Current Topics in Developmental Biology series, covers major topics of research in myogenesis, with a particular emphasis on regeneration and muscle disease. It includes contributions from an international board of authors, providing a comprehensive set of reviews. Covers major topics of research in myogenesis Contains invaluable contributions from an international board of authors Provides a comprehensive set of reviews
Myogenesis
DOWNLOAD
FREE 30 Days
Author : Joseph X. Dimario
language : en
Publisher: Humana Press
Release Date : 2016-05-01
Myogenesis written by Joseph X. Dimario and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-01 with Science categories.
This volume in the Methods in Molecular Biology series presents detailed, step-by-step methods for protocols used in the study of the molecular and cellular biology of skeletal muscle cells. Includes lists of materials and reagents, tips and pitfalls."
Stem Cells And Cell Signalling In Skeletal Myogenesis
DOWNLOAD
FREE 30 Days
Author : D.A. Sassoon
language : en
Publisher: Elsevier
Release Date : 2002-02-08
Stem Cells And Cell Signalling In Skeletal Myogenesis written by D.A. Sassoon and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-02-08 with Science categories.
Skeletal muscle development is perhaps one of the best understood processes at the molecular, cellular and organismal level due in large part to the fact that primary myogenic cells (myoblasts) will grow and subsequently differentiate into myotubes in culture. With the advent of reverse mouse genetics, many of the observations gained through the study of myogenic cells in vitro have been directly tested in vivo. What has emerged is a complex but cohesive story of how myogenic cells are initially specified in the vertebrate embryo and how muscle fibers ultimately achieve their respective identities (i.e. fast versus slow) to perform their function. This collection of chapters is focused on these developments. The book discusses old and new directions for the skeletal muscle field and points out directions where the field may eventually progress.
Vertebrate Myogenesis
DOWNLOAD
FREE 30 Days
Author : Beate Brand-Saberi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-03
Vertebrate Myogenesis written by Beate Brand-Saberi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-03 with Science categories.
The development of vertebrate muscle has long been a major area of research in developmental biology. During the last decade, novel technical approaches have allowed us to unravel to a large extent the mechanisms underlying muscle formation, and myogenesis has become one of the best-understood paradigms for cellular differentiation. This book concisely summarizes our current knowledge about muscle development in vertebrates, from the determination of muscle precursors to terminal differentiation. Each chapter has been written by an expert in the field, and particular emphasis has been placed on the different developmental and molecular pathways followed by the three types of vertebrate musculature - skeletal, heart and smooth muscle.
Vertebrate Myogenesis
DOWNLOAD
FREE 30 Days
Author : Beate Brand-Saberi
language : en
Publisher: Springer
Release Date : 2014-10-25
Vertebrate Myogenesis written by Beate Brand-Saberi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-25 with Science categories.
This book addresses the differentiation control of skeletal muscle in different locations of the vertebrate body Particular attention is paid to novel regulatory molecules and signals as well as the heterogeneity of origin that have revealed a developmental overlap between skeletal and cardiac muscle. Different functional muscle groups are the product of the evolution of the vertebrate classes, making a phylogenetic comparison worthwhile for understanding the role of muscle stem cells and precursors in myogenesis. New insights into the hierarchy of transcription factors, particularly in the context of these different muscle groups have been gained from detailed investigations of the spatio-temporal and regulatory relationships derived from mouse and zebrafish genetics and avian microsurgery. Importantly, epigenetic mechanisms that have surfaced recently, in particular the role of MyomiRs, are also surveyed. With an eye to the human patient, encouraging results have been generated that identify parallels between embryonic myogenesis and regenerating myofibers due to common regulatory molecules. On the other hand, both processes differ considerably in quality and complexity of the processes employed. Interestingly, the heterogeneity in embryonic sources from which skeletal muscle groups in the vertebrate including the human body take origin is paralleled by differences in their susceptibility to particular muscle dystrophies as well as by the characteristics of the satellite cells involved in regeneration. The progress that has been made in the field of muscle stem cell biology, with special focus on the satellite cells, is outlined in this book by experts in the field. The authors review recent insights of the heterogeneous nature of these satellite cells regarding their gene signatures and regeneration potential. Furthermore, an improved understanding of muscle stem cells seems only possible when we study the impact of the cell environment on efficient stem cell replacement therapies for muscular dystrophies, putting embryological findings from different vertebrate classes and stem cell approaches into context.
Myogenesis
DOWNLOAD
FREE 30 Days
Author : Sissel Beate Rønning
language : en
Publisher:
Release Date : 2019
Myogenesis written by Sissel Beate Rønning and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Cytology categories.
Skeletal Muscle Development
DOWNLOAD
FREE 30 Days
Author : James G. Ryall
language : en
Publisher: Methods in Molecular Biology
Release Date : 2018-06-25
Skeletal Muscle Development written by James G. Ryall and has been published by Methods in Molecular Biology this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-25 with Science categories.
Role Of Membrane Fluctuations And Tension In Cell Fusion During Myogenesis
DOWNLOAD
FREE 30 Days
Author : Madhura Chakraborty
language : en
Publisher: Mohammed Abdul Sattar
Release Date : 2023-12-23
Role Of Membrane Fluctuations And Tension In Cell Fusion During Myogenesis written by Madhura Chakraborty and has been published by Mohammed Abdul Sattar this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-23 with Medical categories.
Myogenesis is the formation of adult skeletal muscle from muscle precursor cells. Muscle tissues make up the largest body tissues in an organism. Skeletal muscle is essential for locomotion, and movement and is voluntarily controlled by the organism, unlike cardiac and smooth muscle. It has a highly organized cytoskeletal system. One of the distinct characteristics of skeletal muscle is the striation contributed by the repeating unit of actin and myosin, together they form a single myofiber. This repeating unit of actin and myosin, known as sarcomere, establishes the skeletal muscle unit. If we investigate the developmental origin of skeletal muscle, it starts from the paraxial mesoderm. Paraxial mesoderm is a tissue formed in blastopore or primitive streak during the process of gastrulation. During embryo axis elongation, at the posterior tip of the embryo paraxial mesoderm forms presomitic mesoderm. The anterior part of the transient presomitic mesoderm structure is committed to form somite. It is the somite from where myogenesis starts. Initiated with skeletal myoblast cells, myogenesis involves proliferation and differentiation which ultimately leads to the formation of multinucleated myofibers by the fusion of mononucleated myoblasts and myocytes. A vast number of transcription factors control the process of myogenesis. These factors are known as myogenic regulatory factors (MRFs) and are member of basic helix loop helix family transcription factors. Activation of these MRFs is the hallmark of the initiation of myogenesis. Here we discussed different factors that contributed to the various stages of myogenesis starting from the embryonic stage to tissue formation. In general, muscle development has two major phases, one is embryonic developmental phase from where skeletal muscle tissue develops and another is muscle regeneration which is more prominent in adult muscle tissue after facing injury. Both development and regeneration need regulation by MRFs. The analysis of cell fusion and the mechanism behind it started long back in different systems. Starting from the embryonic stages we have found cell fusion as a normal physiological phenomenon in neural cell, yeast reproduction, exocytosis, macrophage, and muscle cells. Here, we addressed the fusion of mouse myoblasts where two or more myoblast cells fused to form multinucleated myotubes. Apart from the vertebrate system, mechanism of myoblast fusion has also been established in Drosophila and zebrafish systems. Despite the differences in gene expression, the fundamental mechanism of muscle fusion remains the same across systems.
Regulation Of Commitment And Differentiation During Skeletal Myogenesis Microform
DOWNLOAD
FREE 30 Days
Author : Helen Petropoulos
language : en
Publisher: National Library of Canada = Bibliothèque nationale du Canada
Release Date : 2002
Regulation Of Commitment And Differentiation During Skeletal Myogenesis Microform written by Helen Petropoulos and has been published by National Library of Canada = Bibliothèque nationale du Canada this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.
The multi-step process of skeletal muscle development begins with the specification and commitment of precursor cells to the muscle program. Committed cells express the myogenic regulatory transcription factors that control skeletal muscle differentiation. Utilizing the P19 cell system, I have examined the mechanisms by which various factors regulate the expression and activity of the myogenic factors during commitment and differentiation of skeletal muscle. I have shown that the signaling molecule, Wnt3a, acts via nuclear beta-catenin to activate the expression of somite transcription factors including Gli2, Pax3, Six1 and Mox1. beta-catenin was shown to be sufficient and essential for the expression of these somite factors and skeletal muscle development during P19 cell differentiation. Furthermore, I have shown that Gli2 expression induces the expression of Pax4, Mox1 and the myogenic factors leading to skeletal myogenesis. Expression of a dominant negative form of Gli2 indicates that Gli2 activity is necessary for skeletal muscle development. The observation that Pax3 expression could not compensate for the loss of functional Gli2 suggests that the activity of Gli2 and Pax3 during skeletal myogenesis may be interdependent. I also examined the mechanism by which E type binding partners may inhibit activity of the myogenic regulatory factors. Full length forms of E12/E47, as well as ITF-2B, were found to inhibit MyoD activity on exogenous but not endogenous promoters. Therefore, the ability of the E type factors to negatively regulate MyoD activity is contingent on the context of the E box site. In conclusion, these studies further elucidate the mechanisms by which various factors regulate the myogenic regulatory factors during the processes of commitment and differentiation during skeletal muscle development.